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1. 发明申请

US20090252391A1 Method for assisting in diagnosis of cerebral diseases and apparatus thereof 有权
标题翻译：协助诊断脑疾病的方法及其装置
公开(公告)号：US20090252391A1
公开(公告)日：2009-10-08
申请号：US11990687
申请日：2005-08-22
申请人： Hiroshi Matsuda , Tetsutaro Ono , Seiji Matsuba
发明人： Hiroshi Matsuda , Tetsutaro Ono , Seiji Matsuba
IPC分类号： G06K9/00
CPC分类号： A61B5/055 , A61B5/4088 , G06F19/00 , G06F19/321 , G06T7/0012 , G06T2207/10072 , G06T2207/30016 , G16H50/20
摘要： Input MRI brain images are positioned so as to correct a spatial deviation, gray matter tissues are extracted from these images to effect a first image smoothing, the thus-obtained images are subjected to anatomical standardization, a second image smoothing is effected, the gray level is corrected, brain images after correction are statistically compared with MRI brain images of normal cases, thereby providing the diagnosis result. In this instance, the brain images are automatically checked for input images regarding the resolution dot density and the like, the result of gray matter tissue extraction and the result of anatomical standardization, by which specifications of input images and the like can be confirmed objectively and automatically to make a diagnosis automatically by image processing. Further, an ROI-based analysis is made to provide the analysis result as the diagnosis result.
摘要翻译：定位输入MRI脑图像以校正空间偏差，从这些图像中提取灰质组织以进行第一图像平滑处理，由此获得的图像进行解剖标准化，实现第二图像平滑化，灰度级校正后的脑图像与正常病例的MRI脑图像进行统计学比较，从而提供诊断结果。在这种情况下，自动检查大脑图像关于分辨率点密度等的输入图像，灰质组织提取的结果和解剖标准化的结果，由此可以客观地确认输入图像等的规格，自动通过图像处理自动进行诊断。此外，进行基于ROI的分析以提供分析结果作为诊断结果。

2. 发明申请

US20120195485A1 MEDICAL IMAGE DISPLAY PROCESSING METHOD, DEVICE, AND PROGRAM 有权
标题翻译：医学图像显示处理方法，设备和程序
公开(公告)号：US20120195485A1
公开(公告)日：2012-08-02
申请号：US13497447
申请日：2010-09-17
申请人： Seiji Matsuba , Tetsutaro Ono , Tomoaki Goto , Kunihiko Kasahara , Hiroshi Matsuda
发明人： Seiji Matsuba , Tetsutaro Ono , Tomoaki Goto , Kunihiko Kasahara , Hiroshi Matsuda
IPC分类号： G06K9/46
CPC分类号： A61B5/0263 , A61B5/055 , A61B5/4064 , G01R33/4838 , G01R33/5608 , G01R33/56366 , G06T7/0014 , G06T7/11 , G06T2207/10088 , G06T2207/20221 , G06T2207/30016 , G06T2207/30104
摘要： When brain images are inputted through MRI (Magnetic Resonance Imaging) and subjected to image processing to assist the diagnosis of brain diseases, functional and morphological images in an ASL coordinate system are inputted from the head of a subject by an ASL (Arterial Spin Labeling) imaging method using an MRI device. The inputted functional images are subjected to mask processing to extract only the region of cerebral parenchyma, and functional images of only the extracted region of the cerebral parenchyma are thereby produced and displayed to be overlaid on the morphological images. In this manner, a functional image such as a perfusion weighted image of only the region of the cerebral parenchyma can be extracted and displayed overlaid on a morphological image.
摘要翻译：当通过MRI（磁共振成像）输入脑图像并进行图像处理以辅助脑疾病的诊断时，ASL坐标系中的功能和形态图像通过ASL（动脉自旋标记）从受试者的头部输入，使用MRI装置的成像方法。输入的功能图像进行掩模处理以仅提取脑实质区域，由此产生并显示仅提取的脑实质区域的功能图像以覆盖在形态图像上。以这种方式，可以提取并显示覆盖在形态学图像上的功能图像，例如仅仅脑实质区域的灌注加权图像。

3. 发明授权

US08218835B2 Method for assisting in diagnosis of cerebral diseases and apparatus thereof 有权
标题翻译：协助诊断脑疾病的方法及其装置
公开(公告)号：US08218835B2
公开(公告)日：2012-07-10
申请号：US11990687
申请日：2005-08-22
申请人： Hiroshi Matsuda , Tetsutaro Ono , Seiji Matsuba
发明人： Hiroshi Matsuda , Tetsutaro Ono , Seiji Matsuba
IPC分类号： G06K9/00 , G06K9/62 , G06K9/74
CPC分类号： A61B5/055 , A61B5/4088 , G06F19/00 , G06F19/321 , G06T7/0012 , G06T2207/10072 , G06T2207/30016 , G16H50/20
摘要： Input MRI brain images are positioned so as to correct a spatial deviation, gray matter tissues are extracted from these images to effect a first image smoothing, the thus-obtained images are subjected to anatomical standardization, a second image smoothing is effected, the gray level is corrected, brain images after correction are statistically compared with MRI brain images of normal cases, thereby providing the diagnosis result. In this instance, the brain images are automatically checked for input images regarding the resolution dot density and the like, the result of gray matter tissue extraction and the result of anatomical standardization, by which specifications of input images and the like can be confirmed objectively and automatically to make a diagnosis automatically by image processing. Further, an ROI-based analysis is made to provide the analysis result as the diagnosis result.
摘要翻译：定位输入MRI脑图像以校正空间偏差，从这些图像中提取灰质组织以进行第一图像平滑处理，由此获得的图像进行解剖标准化，实现第二图像平滑化，灰度级校正后的脑图像与正常病例的MRI脑图像进行统计学比较，从而提供诊断结果。在这种情况下，自动检查大脑图像关于分辨率点密度等的输入图像，灰质组织提取的结果和解剖标准化的结果，由此可以客观地确认输入图像等的规格，自动通过图像处理自动进行诊断。此外，进行基于ROI的分析以提供分析结果作为诊断结果。

4. 发明授权

US08750584B2 Medical image display processing method, device, and program 有权
标题翻译：医疗图像显示处理方法，设备和程序
公开(公告)号：US08750584B2
公开(公告)日：2014-06-10
申请号：US13497447
申请日：2010-09-17
申请人： Seiji Matsuba , Tetsutaro Ono , Tomoaki Goto , Kunihiko Kasahara , Hiroshi Matsuda
发明人： Seiji Matsuba , Tetsutaro Ono , Tomoaki Goto , Kunihiko Kasahara , Hiroshi Matsuda
IPC分类号： G06K9/00 , A61B5/05 , A61B5/04
CPC分类号： A61B5/0263 , A61B5/055 , A61B5/4064 , G01R33/4838 , G01R33/5608 , G01R33/56366 , G06T7/0014 , G06T7/11 , G06T2207/10088 , G06T2207/20221 , G06T2207/30016 , G06T2207/30104
摘要： When brain images are inputted through MRI (Magnetic Resonance Imaging) and subjected to image processing to assist the diagnosis of brain diseases, functional and morphological images in an ASL coordinate system are inputted from the head of a subject by an ASL (Arterial Spin Labeling) imaging method using an MRI device. The inputted functional images are subjected to mask processing to extract only the region of cerebral parenchyma, and functional images of only the extracted region of the cerebral parenchyma are thereby produced and displayed to be overlaid on the morphological images. In this manner, a functional image such as a perfusion weighted image of only the region of the cerebral parenchyma can be extracted and displayed overlaid on a morphological image.
摘要翻译：当通过MRI（磁共振成像）输入脑图像并进行图像处理以辅助脑疾病的诊断时，ASL坐标系中的功能和形态图像通过ASL（动脉自旋标记）从受试者的头部输入，使用MRI装置的成像方法。输入的功能图像进行掩模处理以仅提取脑实质区域，由此产生并显示仅提取的脑实质区域的功能图像以覆盖在形态图像上。以这种方式，可以提取并显示覆盖在形态学图像上的功能图像，例如仅仅脑实质区域的灌注加权图像。

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