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1. 发明授权

US07291129B2 Apparatus and methods for treating female urinary incontinence 失效
标题翻译：女性尿失禁治疗的装置及方法
公开(公告)号：US07291129B2
公开(公告)日：2007-11-06
申请号：US10207689
申请日：2002-07-25
申请人： Hong Li , Peter S Edelstein , John T To , Simon W. H. Thomas , Benjamin T Nordell
发明人： Hong Li , Peter S Edelstein , John T To , Simon W. H. Thomas , Benjamin T Nordell
IPC分类号： A61M5/178
CPC分类号： A61B18/1477 , A61B18/1485 , A61B2018/00029 , A61B2018/00285 , A61B2018/00523 , A61B2018/00553 , A61B2018/00916 , A61B2218/007 , A61N1/06
摘要： Apparatus and methods are provided for treating female urinary incontinence by injecting a bulking agent at the interface between the mucosal and submucosal layers of the urethral wall. The remodeling device comprises an elongated shaft preferably having means for forming a localized inward protrusion of the urethral wall, and a needle, movable between retracted and deployed positions, for delivering a bulking agent into the urethral wall in the vicinity of the localized inward protrusion to thereby reduce or eliminate symptoms associated with urinary incontinence.
摘要翻译：提供了通过在尿道壁的粘膜和粘膜下层之间的界面处注射填充剂来治疗女性尿失禁的装置和方法。重塑装置包括细长轴，优选地具有用于形成尿道壁的局部向内突出的装置，以及可在缩回和展开位置之间移动的针，用于将填充剂输送到局部向内突出部附近的尿道壁中，从而减少或消除与尿失禁相关的症状。

2. 发明授权

US08465482B2 Apparatus and methods for treating female urinary incontinence 有权
公开(公告)号：US08465482B2
公开(公告)日：2013-06-18
申请号：US13443713
申请日：2012-04-10
申请人： Simon W. H. Thomas , Peter S. Edelstein , John T. To , Benjamin T. Nordell , Stuart D. Edwards
发明人： Simon W. H. Thomas , Peter S. Edelstein , John T. To , Benjamin T. Nordell , Stuart D. Edwards
IPC分类号： A61B18/18
CPC分类号： A61B18/00 , A61B17/0625 , A61B18/02 , A61B18/14 , A61B18/1477 , A61B18/1485 , A61B2017/00805 , A61B2017/00867 , A61B2018/00029 , A61B2018/00035 , A61B2018/00178 , A61B2018/00285 , A61B2018/00523 , A61B2018/00553 , A61B2018/00559 , A61B2018/00916 , A61B2018/1425 , A61B2018/143 , A61B2218/007 , A61N1/06 , A61N7/022 , C08L2201/12
摘要： Apparatus and methods are provided for treating female urinary incontinence by applying a form of energy to tissue in the vicinity of the urethra and/or bladder outlet to change tissue compliance without substantially narrowing the urethral and/or bladder outlet lumen. The apparatus comprises an elongated shaft having a means for treating urethral tissue and an expandable member deployable distal of the means for treating. The expandable member is configured to be anchored against the bladder outlet to dispose the means for treating at a desired treatment site in the urethra using only tactile feedback. The means for treating may include a needleless RF electrode, an ultrasound transducer, or a cryogenic probe configured to be advanced through a hollow needle, each of which are designed to reduce or eliminate symptoms associated with urinary incontinence.

3. 发明申请

US20100168733A1 TREATMENT OF TISSUE IN SPHINCTERS, SINUSES, AND ORIFICES 失效
标题翻译：治疗组织，细胞和组织中的组织
公开(公告)号：US20100168733A1
公开(公告)日：2010-07-01
申请号：US12648249
申请日：2009-12-28
申请人： STUART D. EDWARDS , SIMON W. H. THOMAS
发明人： STUART D. EDWARDS , SIMON W. H. THOMAS
IPC分类号： A61B18/18
CPC分类号： A61N1/0514 , A61B18/18 , A61B2018/0212 , A61N1/06 , A61N1/403
摘要： The invention comprises a method and apparatus for treatment of a body part. More particularly, a method and apparatus for heat treatment of tissue using a catheter inserted into a body part is described along with means for positioning the catheter and means for positioning a set of electrodes relative to a tissue sample for treatment. Still more particularly, radio frequency energy at about 400 to 500 kilohertz is used to provide heat for the tissue treatment.
摘要翻译：本发明包括一种用于治疗身体部位的方法和装置。更具体地，描述了使用插入到身体部分中的导管来热处理组织的方法和装置，以及用于定位导管的装置和用于相对于组织样本定位一组电极的装置用于治疗。更具体地，使用约400至500千赫兹的射频能量来为组织处理提供热量。

4. 发明申请

US20060058780A1 Treatment of tissue in sphincters, sinuses, and orifices 有权
公开(公告)号：US20060058780A1
公开(公告)日：2006-03-16
申请号：US11207677
申请日：2005-08-18
申请人： Stuart D. Edwards , Simon W. H. Thomas
发明人： Stuart D. Edwards , Simon W. H. Thomas
IPC分类号： A61F2/00
CPC分类号： A61N1/06 , A61N1/403
摘要： The invention comprises a method and apparatus for treatment of a body part. More particularly, a method and apparatus for heat treatment of tissue using a catheter inserted into a body part is described along with means for positioning the catheter and means for positioning a set of electrodes relative to a tissue sample for treatment. Still more particularly, radio frequency energy at about 400 to 500 kilohertz is used to provide heat for the tissue treatment.

5. 发明授权

US08412318B2 Treatment of tissue in sphincters, sinuses, and orifices 有权
公开(公告)号：US08412318B2
公开(公告)日：2013-04-02
申请号：US11207677
申请日：2005-08-18
申请人： Stuart D. Edwards , Simon W. H. Thomas
发明人： Stuart D. Edwards , Simon W. H. Thomas
IPC分类号： A61N1/30
CPC分类号： A61N1/06 , A61N1/403
摘要： The invention comprises a method and apparatus for treatment of a body part. More particularly, a method and apparatus for heat treatment of tissue using a catheter inserted into a body part is described along with means for positioning the catheter and means for positioning a set of electrodes relative to a tissue sample for treatment. Still more particularly, radio frequency energy at about 400 to 500 kilohertz is used to provide heat for the tissue treatment.

6. 发明授权

US08353908B2 Treatment of tissue in sphincters, sinuses, and orifices 失效
标题翻译：治疗括约肌，鼻窦和孔的组织
公开(公告)号：US08353908B2
公开(公告)日：2013-01-15
申请号：US12648249
申请日：2009-12-28
申请人： Stuart D. Edwards , Simon W. H. Thomas
发明人： Stuart D. Edwards , Simon W. H. Thomas
IPC分类号： A61B18/18
CPC分类号： A61N1/0514 , A61B18/18 , A61B2018/0212 , A61N1/06 , A61N1/403
摘要： The invention comprises a method and apparatus for treatment of a body part. More particularly, a method and apparatus for heat treatment of tissue using a catheter inserted into a body part is described along with means for positioning the catheter and means for positioning a set of electrodes relative to a tissue sample for treatment. Still more particularly, radio frequency energy at about 400 to 500 kilohertz is used to provide heat for the tissue treatment.
摘要翻译：本发明包括一种用于治疗身体部位的方法和装置。更具体地，描述了使用插入到身体部分中的导管来热处理组织的方法和装置，以及用于定位导管的装置和用于相对于组织样本定位一组电极的装置用于治疗。更具体地，使用约400至500千赫兹的射频能量来为组织处理提供热量。

7. 发明授权

US08177781B2 Apparatus and methods for treating female urinary incontinence 有权
标题翻译：女性尿失禁治疗的装置及方法
公开(公告)号：US08177781B2
公开(公告)日：2012-05-15
申请号：US11431213
申请日：2006-05-10
申请人： Simon W. H. Thomas , Peter S. Edelstein , John T. To , Benjamin T. Nordell , Stuart D. Edwards
发明人： Simon W. H. Thomas , Peter S. Edelstein , John T. To , Benjamin T. Nordell , Stuart D. Edwards
IPC分类号： A61B18/18
CPC分类号： A61B18/00 , A61B17/0625 , A61B18/02 , A61B18/14 , A61B18/1477 , A61B18/1485 , A61B2017/00805 , A61B2017/00867 , A61B2018/00029 , A61B2018/00035 , A61B2018/00178 , A61B2018/00285 , A61B2018/00523 , A61B2018/00553 , A61B2018/00559 , A61B2018/00916 , A61B2018/1425 , A61B2018/143 , A61B2218/007 , A61N1/06 , A61N7/022 , C08L2201/12
摘要： Apparatus and methods are provided for treating female urinary incontinence by applying a form of energy to tissue in the vicinity of the urethra and/or bladder outlet to change tissue compliance without substantially narrowing the urethral and/or bladder outlet lumen. The apparatus comprises an elongated shaft having a means for treating urethral tissue and an expandable member deployable distal of the means for treating. The expandable member is configured to be anchored against the bladder outlet to dispose the means for treating at a desired treatment site in the urethra using only tactile feedback. The means for treating may include a needleless RF electrode, an ultrasound transducer, or a cryogenic probe configured to be advanced through a hollow needle, each of which are designed to reduce or eliminate symptoms associated with urinary incontinence.
摘要翻译：提供了用于通过向尿道和/或膀胱出口附近的组织施加能量来改变组织依从性而不使尿道和/或膀胱出口腔基本上变窄来治疗女性尿失禁的装置和方法。该装置包括细长轴，其具有用于治疗尿道组织的装置和可展开装置的可扩展构件。可膨胀构件被构造成锚固在膀胱出口上，以仅使用触觉反馈来将用于治疗的装置设置在尿道中的期望的治疗部位。用于治疗的装置可以包括无针RF电极，超声换能器或构造成通过中空针前进的低温探针，每个都被设计为减少或消除与尿失禁相关的症状。

8. 发明授权

US5411024A Fetal pulse oximetry sensor 失效
标题翻译：胎儿脉搏血氧饱和度传感器
公开(公告)号：US5411024A
公开(公告)日：1995-05-02
申请号：US167334
申请日：1993-12-15
申请人： Simon W. H. Thomas , William R. Pruehsner
发明人： Simon W. H. Thomas , William R. Pruehsner
IPC分类号： A61B5/0245 , A61B5/00 , A61B5/0448 , A61B5/145 , A61B5/1455 , A61B5/1464
CPC分类号： A61B5/1464 , A61B5/0448 , A61B5/14542 , A61B5/4362 , A61B5/6882 , A61B2503/02
摘要： A fetal pulse oximetry sensor device containing a pulse oximetry sensor is disclosed. The device also includes a spiral for fetal attachment. One or both of the light emitting portion and light detecting portion of the pulse oximetry sensor is spring biased to be moveable with respect to the body of the device. Alternatively, the light emitting portion and light detecting portion may be mounted within the housing of the device, with the housing being spring biased towards the fetal skin. In this manner, the pulse oximetry sensor is maintained in intimate contact with the fetal tissue. This provides for accurate oximetry measurements since the errors due to the detection of unattenuated or non-absorbed light passing directly from the light emitter to the light detector, are significantly reduced. The fetal attachment spiral may also include a fetal EKG electrode, in which case the device may be used as both a fetal pulse oximeter and a fetal heart rate monitor.
摘要翻译：公开了一种含有脉搏血氧饱和度传感器的胎儿脉搏血氧饱和度传感器装置。该装置还包括用于胎儿附着的螺旋。脉搏血氧饱和度传感器的发光部分和光检测部分中的一个或两个被弹簧偏压以相对于装置的主体移动。或者，发光部分和光检测部分可以安装在装置的壳体内，其中壳体被弹性地朝向胎儿皮肤偏置。以这种方式，脉搏血氧饱和度传感器保持与胎儿组织紧密接触。这提供了精确的血氧定量测量，因为由于直接从光发射器到光检测器的非衰减或非吸收光的检测的误差显着降低。胎儿附着螺旋还可以包括胎儿EKG电极，在这种情况下，该装置可以用作胎儿脉搏血氧计和胎儿心率监测器。

9. 发明授权

US07722338B2 Peristaltic pump providing simplified loading and improved tubing kink resistance 有权
标题翻译：蠕动泵提供简化的负载和改善的扭结线圈阻力
公开(公告)号：US07722338B2
公开(公告)日：2010-05-25
申请号：US11056086
申请日：2005-02-10
申请人： Benjamin T. Nordell , Peter S. Edelstein , Simon W. H. Thomas
发明人： Benjamin T. Nordell , Peter S. Edelstein , Simon W. H. Thomas
IPC分类号： F04B45/06 , F04B43/12 , F04B43/08
CPC分类号： F04B43/1253
摘要： A peristaltic pump is provided that simplifies the loading of tubing and automatically self-centers the tubing relative to the pump wheel, wherein the pump includes an elongated arm having slotted pinch forks for engaging the tubing. The pinch forks are arranged substantially tangential to the pump wheel to reduce tubing kinking. The pump further includes a spring-loaded clamp that moves the elongated arm between engaged and disengaged positions, the clamp optionally including a sensor element used to detect when the pump is ready for operation.
摘要翻译：提供了一种蠕动泵，其简化了管道的装载并且自动使管道相对于泵轮自中心，其中泵包括细长的臂，其具有用于接合管道的开槽的夹紧叉。夹紧叉布置成基本上与泵轮相切，以减少油管扭结。泵还包括弹簧加载的夹具，其将细长臂移动在接合位置和脱离位置之间，夹具可选地包括用于检测泵何时准备运行的传感器元件。

10. 发明授权

US07306591B2 Apparatus and methods for treating female urinary incontinence 有权
公开(公告)号：US07306591B2
公开(公告)日：2007-12-11
申请号：US10273900
申请日：2002-10-16
申请人： Simon W. H. Thomas , Peter S. Edelstein , John T. To , Benjamin T. Nordell
发明人： Simon W. H. Thomas , Peter S. Edelstein , John T. To , Benjamin T. Nordell
IPC分类号： A61B18/18
CPC分类号： A61B18/00 , A61B17/0625 , A61B18/02 , A61B18/14 , A61B18/1477 , A61B18/1485 , A61B2017/00805 , A61B2017/00867 , A61B2018/00029 , A61B2018/00035 , A61B2018/00178 , A61B2018/00285 , A61B2018/00523 , A61B2018/00553 , A61B2018/00559 , A61B2018/00916 , A61B2018/1425 , A61B2018/143 , A61B2218/007 , A61N1/06 , A61N7/022 , C08L2201/12
摘要： Apparatus and methods are provided for treating female urinary incontinence by applying a form of energy to tissue in the vicinity of the urethra and/or bladder outlet to change tissue compliance without substantially narrowing the urethral and/or bladder outlet lumen. The apparatus comprises an elongated shaft having a means for treating urethral tissue and an expandable member deployable distal of the means for treating. The expandable member is configured to be anchored against the bladder outlet to dispose the means for treating at a desired treatment site in the urethra using only tactile feedback. The means for treating may include a needleless RF electrode, an ultrasound transducer, or a cryogenic probe configured to be advanced through a hollow needle, each of which are designed to reduce or eliminate symptoms associated with urinary incontinence.

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