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1. 发明申请

US20170082218A1 Waterproofing Water Combinations 有权
公开(公告)号：US20170082218A1
公开(公告)日：2017-03-23
申请号：US15364698
申请日：2016-11-30
申请人： Stephen JOHNSON
发明人： Stephen JOHNSON
IPC分类号： F16L5/02 , E04B1/66
CPC分类号： F16L5/02 , E03C1/02 , E03C1/04 , E04B1/66
摘要： The present invention relates generally to a system for waterproofing a wall 7 having a wall opening through which a water combination 6 extends. The system comprises a sleeve 1 including a collar 12 having a resiliently flexible portion adapted to expand to fit about the water combination 6. The waterproofing system also comprises a coupling element 3 separate from the sleeve 1. The coupling element 3 is arranged to seal to the sleeve 1 and the wall 7 or associated tiles 8 to which the water combination 6 is mounted.

2. 发明授权

US09183702B2 Gaming machine with mine feature 有权
标题翻译：具有矿山功能的游戏机
公开(公告)号：US09183702B2
公开(公告)日：2015-11-10
申请号：US10690852
申请日：2003-10-21
申请人： Christopher Stevens , Stephen Johnson
发明人： Christopher Stevens , Stephen Johnson
IPC分类号： G07F17/32
CPC分类号： G07F17/3262 , G07F17/32 , G07F17/3267
摘要： A gaming machine has a display and a game controller arranged to control images of symbols displayed on the display. The game controller is arranged to play a game wherein at least one random event is caused to be displayed on the display means and, if a predefined winning event occurs, the machine awards a prize. The gaming machine further comprises a game feature where, upon being awarded at least one prize in the feature, a player is offered a choice and, if the choice results in a successful outcome, the player has the option of continuing with the feature but, if the choice results in an unsuccessful outcome, the feature ends and a portion, but not all, of a total prize accumulated up to termination of the feature is forfeited.
摘要翻译：游戏机具有显示器和游戏控制器，被布置为控制显示在显示器上的符号的图像。游戏控制器被布置为玩游戏，其中至少一个随机事件被显示在显示装置上，并且如果发生预定义的胜利事件，则机器奖励奖品。游戏机还包括游戏特征，其中在被授予至少一个该特征的奖品时，向玩家提供选择，并且如果选择导致成功的结果，玩家可以选择继续该特征，如果选择导致不成功的结果，则特征结束，并且部分（但不是全部）累积到该特征的终止的总奖金被没收。

3. 发明申请

US20140165705A1 Sample Line Management In A Fluid Analyzer System 有权
标题翻译：流体分析仪系统中的样品管线管理
公开(公告)号：US20140165705A1
公开(公告)日：2014-06-19
申请号：US13714618
申请日：2012-12-14
申请人： Yonquan Li , Daniel E. Glenn , K. Stephen Johnson, JR. , Dieter Kita
发明人： Yonquan Li , Daniel E. Glenn , K. Stephen Johnson, JR. , Dieter Kita
IPC分类号： G01N33/00 , G01N1/44
CPC分类号： G01N1/44 , G01N1/2247 , G01N33/0009
摘要： In a first mode, a monitoring system inputs humidified gas through at least a portion of a conduit. At least a portion of the water in the humidified gas adheres to the inner surface of the conduit, inhibiting contaminants in the gas sample from adhering to the inner surface. The water in the humidified gas may also push any contaminants adhered to the surface of the sample line back out the sample line. In a second mode, after previously passing the humidified gas through the conduit, the monitoring system controls a flow of a gas sample including the contaminants through the conduit to a gas analyzer. The one or more layer of water on the inner surface of the conduit prevents or reduces a buildup of undesirable contaminants on an inner surface of a conduit that conveys gas samples.
摘要翻译：在第一模式中，监测系统通过导管的至少一部分输入加湿气体。加湿气体中的至少一部分水粘附到导管的内表面，从而抑制气体样品中的污染物粘附到内表面。加湿气体中的水也可能将附着在样品管线表面的任何污染物推回出样品管线。在第二模式中，在先前通过加湿气体通过导管之后，监测系统通过导管将含有污染物的气体样品的流量控制到气体分析器。导管内表面上的一层或多层水可防止或减少在输送气体样品的导管的内表面上积聚不需要的污染物。

4. 发明授权

US08517567B1 LED illumination source with improved visual characteristics 有权
公开(公告)号：US08517567B1
公开(公告)日：2013-08-27
申请号：US13686403
申请日：2012-11-27
申请人： James Leahy , Chris Hartswick , Stephen Johnson
发明人： James Leahy , Chris Hartswick , Stephen Johnson
IPC分类号： F21V33/00
摘要： An illumination source is disclosed that features, in one embodiment, an at least generally conical body extending outward along an axis of illumination, a socket supported with respect to the body having a pair of connector surfaces for receiving power and having an axis of insertion at least generally parallel to the axis of illumination, and one or more LED illumination elements supported with respect to the body such that at least a portion of their illumination axes are at least generally parallel to the axis of illumination of the source. A power supply has electrical inputs operatively connected to the socket and electrical outputs operatively connected to the LED illumination elements, and a front face is positioned opposite the socket along the illumination axis. An optical light-directing element is provided separate from any optical process or packaging surfaces built onto the LEDs, is disposed between the LED illumination elements and the front face, and has medial and distal ends, with the distal end being spaced away from the front face.

5. 发明授权

US08144411B2 Multimodal optical imaging 有权
公开(公告)号：US08144411B2
公开(公告)日：2012-03-27
申请号：US12263677
申请日：2008-11-03
申请人： Siavash Yazdanfar , Vernon Thomas Jensen , Stephen Johnson Lomnes
发明人： Siavash Yazdanfar , Vernon Thomas Jensen , Stephen Johnson Lomnes
IPC分类号： G02B5/22 , A61B1/06
CPC分类号： G02B26/008 , G02B7/006 , G02B21/16 , G02B21/361 , G02B23/2407
摘要： Multimodal optical imaging is disclosed. Possible devices include a filter assembly that is capable of rotary action during real time image acquisition. Systems are disclosed that include such filter assemblies, which are detachable or integrated in the systems. Various techniques for capturing image targets using multiple light sources such as white light and fluorescent light are also disclosed.

6. 发明申请

US20120046687A1 Vascular Occlusion Devices 有权
标题翻译：血管闭塞装置
公开(公告)号：US20120046687A1
公开(公告)日：2012-02-23
申请号：US13262546
申请日：2010-04-02
申请人： Julie Marie Trommeter , Michael B. Lyons , Jeffrey Paul Castleberry , Robin Shandas , James Fogelberg , Stephen Johnson
发明人： Julie Marie Trommeter , Michael B. Lyons , Jeffrey Paul Castleberry , Robin Shandas , James Fogelberg , Stephen Johnson
IPC分类号： A61F2/01
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B2017/00477 , A61B2017/00778 , A61B2017/00871 , A61B2017/00898 , A61B2017/12054 , A61L31/04 , A61L31/14 , A61L2400/16 , A61L2430/36
摘要： Shape memory materials (SMM) are formed as coil-shaped vascular occlusion devices upon deployment. Shape memory polymer (SMP) materials are tailored through formulation for specific mechanical behavior of the coils. Concurrent coil diameter changes enhance the relative change in stiffness along the length of the coil. Interconnecting structures (104a/b) are formed on ends of elongated members (102a) in the pre-deployment shape for multiple coil insertion capability within an introducer. Channels (206) are formed in pre-deployment shape, elongate members (202) that allow access for injection of imaging contrast agent or concurrent placement of instruments. A single SMM occlusive device (300) transforms into multiple, smaller diameter coils (302b) in the deployed state to generate a complex occlusive structure. A SMM occlusive device (400) has a collapsed fabric (404) component attached to and extending along a sidewall during storage and insertion, and then deploys as a coil (402b) to form a single- or multiple-layer occlusive fabric surface within a center of the coil (402b).
摘要翻译：形状记忆材料（SMM）在部署时形成为线圈状血管闭塞装置。形状记忆聚合物（SMP）材料通过配方为线圈的特定机械性能而定制。并联线圈直径变化增强沿着线圈长度的刚度的相对变化。互连结构（104a / b）形成在细长构件（102a）的端部中，用于在引导器内用于多个线圈插入能力的预展开形状。通道（206）以预先展开形状形成，细长构件（202）允许进入成像造影剂的注入或仪器的同时放置。单个SMM闭塞装置（300）在展开状态下变换成多个较小直径的线圈（302b），以产生复杂的闭塞结构。 SMM闭塞装置（400）具有在储存和插入期间附着并沿侧壁延伸的塌陷织物（404）部件，然后作为线圈（402b）展开以形成单层或多层闭塞织物表面线圈（402b）的中心。

7. 发明授权

US08093400B2 Compounds useful in therapy 失效
标题翻译：化合物可用于治疗
公开(公告)号：US08093400B2
公开(公告)日：2012-01-10
申请号：US12777522
申请日：2010-05-11
申请人： Justin Stephen Bryans , Patrick Stephen Johnson , Lee Richard Roberts , Thomas Ryckmans
发明人： Justin Stephen Bryans , Patrick Stephen Johnson , Lee Richard Roberts , Thomas Ryckmans
IPC分类号： C07D249/12 , C07D249/08 , C07D249/04 , A61K31/4196 , A61K31/4192
CPC分类号： C07D401/04 , C07D249/08 , C07D249/14 , C07D401/14 , C07D403/04 , C07D405/14 , C07D413/04 , C07D413/14 , C07D471/04
摘要： The present invention provides compounds of formula (I), or pharmaceutically acceptable derivatives thereof wherein the variables Z, Q, Ring A, V, X, Y and Y′ are as defined herein, and pharmaceutical compositions comprising these compounds. The compounds of formula (I) and pharmaceutical compositions comprising them are useful for treating a disorder for which a V1a antagonist is indicated, in particular, dysmenorrhoea.
摘要翻译：本发明提供式（I）化合物或其药学上可接受的衍生物，其中变量Z，Q，环A，V，X，Y和Y'如本文所定义，以及包含这些化合物的药物组合物。式（I）化合物和包含它们的药物组合物可用于治疗指示V1a拮抗剂，特别是痛经的病症。

8. 发明申请

US20110305635A9 MYELIN DETECTION USING BENZOFURAN DERIVATIVES 有权
标题翻译：使用苯唑嘌呤衍生物进行MYELIN检测
公开(公告)号：US20110305635A9
公开(公告)日：2011-12-15
申请号：US12211854
申请日：2008-09-17
申请人： Christina Abucay Tan Hehir , Stephen Johnson Lomnes , Kenneth Michael Fish , Tiberiu Mircea Siclovan , Michael Christopher Montalto , Tunchiao Hubert Lam
发明人： Christina Abucay Tan Hehir , Stephen Johnson Lomnes , Kenneth Michael Fish , Tiberiu Mircea Siclovan , Michael Christopher Montalto , Tunchiao Hubert Lam
IPC分类号： A61K51/04
CPC分类号： G01N33/60 , A61K49/10 , A61K51/0419 , G01N33/6896 , G01N2800/285 , Y10T436/14 , Y10T436/20 , Y10T436/200833
摘要： The present invention relates to methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using a benzofuran compound or its radioisotope derivatives. In one embodiment a method of myelin detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the benzofuran compound, or a derivative of the compound, and determining myelination in the subject by detecting binding in the sample. In one embodiment, the invention provides a method of imaging myelinated tissue in a surgical field of mammalian tissue comprising the steps of contacting the surgical site with the benzofuran compound or a radioisotope derivative of the compound, and detecting binding in the surgical site. In yet another embodiment, a method of imaging spinal cord and spinal nerve root tissue is provided comprising the steps of parenteral administration of a radioisotope derivative of the benzofuran compound and detecting the radioisotope derivative within the spinal canal and intervertebral foramen. Methods of quantification of binding of the benzofuran compound or its derivatives are also provided.
摘要翻译：本发明涉及使用苯并呋喃化合物或其放射性同位素衍生物检测髓磷脂的方法及其在样品中的局部浓度的定量测量。在一个实施方案中，髓鞘蛋白检测的方法包括鉴定患有髓磷脂相关神经病的风险或被诊断患有髓磷脂相关神经病的受试者，所述苯并呋喃化合物或所述化合物的衍生物肠胃外给药，以及通过检测受试者中的结合来确定受试者的髓鞘形成例子。在一个实施方案中，本发明提供了一种在哺乳动物组织的手术领域中成像有髓组织的方法，包括使手术部位与化合物的苯并呋喃化合物或放射性同位素衍生物接触并检测手术部位的结合的步骤。在另一个实施方案中，提供了一种脊髓和脊髓神经根组织成像方法，其包括非肠道给药苯并呋喃化合物的放射性同位素衍生物和检测椎管内的放射性同位素衍生物和椎间孔的步骤。还提供了定量苯并呋喃化合物或其衍生物的结合方法。

9. 发明授权

US07960037B2 Carbon nanotube polymer composition and devices 有权
标题翻译：碳纳米管聚合物组成和装置
公开(公告)号：US07960037B2
公开(公告)日：2011-06-14
申请号：US11293681
申请日：2005-12-02
申请人： Gao Liu , Stephen Johnson , John B. Kerr , Andrew M. Minor , Samuel S. Mao
发明人： Gao Liu , Stephen Johnson , John B. Kerr , Andrew M. Minor , Samuel S. Mao
IPC分类号： H01L51/54
CPC分类号： H01L51/0049 , B82Y10/00 , H01L51/0067 , H01L51/5012 , Y02E10/549 , Y10S428/917
摘要： A thin film device and compound having an anode, a cathode, and at least one light emitting layer between the anode and cathode, the at least one light emitting layer having at least one carbon nanotube and a conductive polymer.
摘要翻译：一种在阳极和阴极之间具有阳极，阴极和至少一个发光层的薄膜器件和化合物，所述至少一个发光层具有至少一个碳纳米管和导电聚合物。

10. 发明授权

US07425569B2 1H-pyrazoles useful in therapy 失效
标题翻译：用于治疗的1H-吡唑
公开(公告)号：US07425569B2
公开(公告)日：2008-09-16
申请号：US11870451
申请日：2007-10-11
申请人： Paul Anthony Bradley , Kevin Neil Dack , Patrick Stephen Johnson , Sarah Elizabeth Skerratt
发明人： Paul Anthony Bradley , Kevin Neil Dack , Patrick Stephen Johnson , Sarah Elizabeth Skerratt
IPC分类号： A61K31/44
CPC分类号： C07D231/18 , C07D401/12
摘要： Compounds of formula (I), or a pharmaceutically acceptable derivative thereof, wherein R1 and R3 independently represent H, C1-6alkyl, C3-8cycloalkyl, or halogen; R2 represents C1-6alkyl, CF3 or aryl; a represents 1 or 2; R4, R5, R7 and R8 independently represent H, C1-6alkyl, C1-6alkyloxy, CN or halogen, or R4 and R5, or R7 and R8, together with the ring to which they are attached form an aryl or heterocyclic fused ring system; X represents C or N; Y represents CH2 or O; R6 represents H, CN or halo provided that, when X represents N, R6 is absent. The compounds are useful for treating endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis, primary and secondary dysmenorrhoea (including symptoms of dyspareunia, dyschexia and chronic pelvic pain), or chronic pelvic pain syndrome.
摘要翻译：式（I）化合物或其药学上可接受的衍生物，其中R 1和R 3独立代表H，C 1-6烷基 C 3-8环烷基或卤素; R 2表示C 1-6烷基，CF 3或芳基; a代表1或2; R 4，R 5，R 7和R 8独立地表示H，C 1-6 C 1-6烷基，C 1-6烷氧基，CN或卤素，或R 4和R 5或R 7 和它们所连接的环连接形成芳基或杂环稠环体系; X表示C或N; Y表示CH 2或O; R 6表示H，CN或卤素，条件是当X表示N时，R 6不存在。这些化合物可用于治疗子宫内膜异位症，子宫肌瘤（平滑肌瘤），月经过多，子宫腺肌症，原发性和继发性痛经（包括性交疼痛，dyschexia和慢性盆腔疼痛症状）或慢性盆腔疼痛综合征。

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