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1. 发明授权

US08961112B2 Torque frame bushing arrangement for gas turbine engine fan drive gear system 有权
标题翻译：用于燃气涡轮发动机风扇驱动齿轮系的扭矩框架衬套布置
公开(公告)号：US08961112B2
公开(公告)日：2015-02-24
申请号：US13429671
申请日：2012-03-26
申请人： James B. Coffin , Richard E. Domonkos , Sunil Sharma
发明人： James B. Coffin , Richard E. Domonkos , Sunil Sharma
IPC分类号： F16H1/28
CPC分类号： F16H57/082 , F02C7/36 , F05D2260/40311 , Y10T29/49464
摘要： A fan drive gear system for a gas turbine engine includes a carrier that supports circumferentially arranged gears. A torque frame has circumferentially arranged fingers with each finger including a bore having a bore axis. A bushing is arranged in each bore and provides an aperture. At least one bushing has a bushing axis offset from the bore axis. A pin is disposed in the aperture and secures the carrier to the torque frame.
摘要翻译：用于燃气涡轮发动机的风扇驱动齿轮系统包括支撑周向布置的齿轮的载体。扭矩框架具有周向布置的指状物，每个指状物包括具有孔轴线的孔。每个孔中布置一个衬套，并提供孔。至少一个衬套具有从孔轴线偏移的衬套轴线。销设置在孔中并将载体固定到扭矩框架上。

2. 发明申请

US20140094445A1 SUBSTITUTED (E)-N'-(1-PHENYLETHYLIDENE)BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIBITORS 有权
标题翻译：取代（E）-N' - （1-苯基乙基）苯甲酰化酶类似物作为HISTONE DEMETHYLASE抑制剂
公开(公告)号：US20140094445A1
公开(公告)日：2014-04-03
申请号：US13586603
申请日：2012-08-15
申请人： Hariprasad Vakayalapati , Venkataswamy Soma , Steven L. Warner , Bret Stephens , David J. Bearss , Sunil Sharma
发明人： Hariprasad Vakayalapati , Venkataswamy Soma , Steven L. Warner , Bret Stephens , David J. Bearss , Sunil Sharma
IPC分类号： C07D295/26 , C07D295/155 , C07D205/04 , C07C311/46
CPC分类号： A61K31/4453 , A61K31/18 , A61K31/397 , A61K31/40 , A61K31/495 , A61K31/5375 , A61K31/5377 , C07C311/16 , C07C311/46 , C07D205/04 , C07D295/155 , C07D295/26
摘要： In one aspect, the invention relates to substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及可用作赖氨酸特异性组蛋白脱甲基酶（包括LSD1）的抑制剂的取代的（E）-N' - （1-苯基亚乙基）苯甲酰肼类似物，其衍生物和相关化合物。制备化合物的合成方法; 包含该化合物的药物组合物; 以及使用化合物和组合物治疗与LSD1功能障碍相关的疾病的方法。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

3. 发明授权

US08703767B2 Substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase BTK inhibitors 有权
标题翻译：取代的N-（3-（嘧啶-4-基）苯基）丙烯酰胺类似物作为酪氨酸受体激酶BTK抑制剂
公开(公告)号：US08703767B2
公开(公告)日：2014-04-22
申请号：US13436963
申请日：2012-04-01
申请人： David J. Bearss , Hariprasad Vankayalapati , Venkataswamy Sorna , Steven L. Warner , Sunil Sharma
发明人： David J. Bearss , Hariprasad Vankayalapati , Venkataswamy Sorna , Steven L. Warner , Sunil Sharma
IPC分类号： A61K31/5377 , A61K31/496 , A61K31/505 , C07D413/02 , C07D239/20 , C07D403/02
CPC分类号： C07D239/48 , C07D239/30 , C07D239/42 , C07D471/04 , C07D487/04
摘要： In one aspect, the invention relates to substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the BTK kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the BTK kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
摘要翻译：一方面，本发明涉及可用作BTK激酶抑制剂的取代的N-（3-（嘧啶-4-基）苯基）丙烯酰胺类似物，其衍生物和相关化合物。制备化合物的合成方法; 包含该化合物的药物组合物; 以及使用该化合物和组合物来治疗与BTK激酶功能障碍相关的疾病的方法。该摘要旨在作为用于在特定技术中进行搜索的扫描工具，而不意在限制本发明。

4. 发明申请

US20130251511A1 TORQUE FRAME BUSHING ARRANGEMENT FOR GAS TURBINE ENGINE FAN DRIVE GEAR SYSTEM 有权
标题翻译：用于气体涡轮发动机风扇驱动齿轮系统的扭矩框架布置布置
公开(公告)号：US20130251511A1
公开(公告)日：2013-09-26
申请号：US13429671
申请日：2012-03-26
申请人： James B. Coffin , Richard E. Domonkos , Sunil Sharma
发明人： James B. Coffin , Richard E. Domonkos , Sunil Sharma
IPC分类号： F02C3/04 , B23P11/00 , F16H57/08
CPC分类号： F16H57/082 , F02C7/36 , F05D2260/40311 , Y10T29/49464
摘要： A fan drive gear system for a gas turbine engine includes a carrier that supports circumferentially arranged gears. A torque frame has circumferentially arranged fingers with each finger including a bore having a bore axis. A bushing is arranged in each bore and provides an aperture. At least one bushing has a bushing axis offset from the bore axis. A pin is disposed in the aperture and secures the carrier to the torque frame.
摘要翻译：用于燃气涡轮发动机的风扇驱动齿轮系统包括支撑周向布置的齿轮的载体。扭矩框架具有周向布置的指状物，每个指状物包括具有孔轴线的孔。每个孔中布置一个衬套，并提供孔。至少一个衬套具有从孔轴线偏移的衬套轴线。销设置在孔中并将载体固定到扭矩框架上。

5. 发明申请

US20050039157A1 Method for mapping a logic circuit to a programmable look up table (LUT) 失效
标题翻译：将逻辑电路映射到可编程查询表（LUT）的方法
公开(公告)号：US20050039157A1
公开(公告)日：2005-02-17
申请号：US10830862
申请日：2004-04-23
申请人： Sunil Sharma , Ajay Tomar , Dhabalendu Samanta
发明人： Sunil Sharma , Ajay Tomar , Dhabalendu Samanta
IPC分类号： G06F17/50 , H03K19/00
CPC分类号： G06F17/5054
摘要： The method for mapping a logic circuit to a plurality of interconnectable, programmable look up tables (LUT) elements includes forming logic element groups including individual logic elements and/or previously formed logic element groups that are capable of being accommodated within the fanin and/or fanout capacity of a target LUT. The method further includes mapping the formed logic element group to the target LUT, and repeating the process for forming logic element groups and mapping to target LUTs for the entire network in a manner such that at each stage only the unmapped logic element/elements and mapped logic element groups of the previous stage are considered for mapping.
摘要翻译：用于将逻辑电路映射到多个可互连的可编程查询表（LUT）元件的方法包括形成逻辑元件组，其包括单独的逻辑元件和/或先前形成的逻辑元件组，所述逻辑元件组能够被容纳在所述扇形元件内和/或目标LUT的扇出容量。该方法还包括将所形成的逻辑元件组映射到目标LUT，并且以这样的方式重复形成逻辑元件组并映射到目标LUT的处理，使得在每个阶段仅将未映射的逻辑元件/元素和映射考虑前一阶段的逻辑单元组进行映射。

6. 发明申请

US20140163017A1 SUBSTITUTED (E)-N'-(1-PHENYLETHYLIDENE)BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIBITORS 有权
公开(公告)号：US20140163017A1
公开(公告)日：2014-06-12
申请号：US13921895
申请日：2013-06-19
申请人： Hariprasad Vankayalapati , Venkataswamy Sorna , Steven L. Warner , Bret Stephens , David J. Bearss , Sunil Sharma
发明人： Hariprasad Vankayalapati , Venkataswamy Sorna , Steven L. Warner , Bret Stephens , David J. Bearss , Sunil Sharma
IPC分类号： C07D231/12 , C07D213/71 , C07D213/61 , C07D207/48 , C07C251/86 , C07C311/37
CPC分类号： A61K31/54 , A61K31/18 , A61K31/40 , A61K31/4453 , A61K31/495 , A61K31/5375 , A61K31/5377 , C07C251/86 , C07C311/16 , C07C311/37 , C07D207/48 , C07D213/53 , C07D213/61 , C07D213/71 , C07D213/81 , C07D231/12 , C07D295/26
摘要： In one aspect, the invention relates to substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

7. 发明授权

US5717911A Relational database system and method with high availability compliation of SQL programs 失效
标题翻译：关系型数据库系统与SQL程序高可用性并发方法
公开(公告)号：US5717911A
公开(公告)日：1998-02-10
申请号：US377287
申请日：1995-01-23
申请人： Louise M. Madrid , Richard A. Meier , Franco Putzolu , Sunil Sharma , Thomas J. O'Shea , James H. Troisi , Hansjorg Zeller , Gary M. Gilbert , Donald S. Maier , Elizabeth G. Davis , Pedro Celis
发明人： Louise M. Madrid , Richard A. Meier , Franco Putzolu , Sunil Sharma , Thomas J. O'Shea , James H. Troisi , Hansjorg Zeller , Gary M. Gilbert , Donald S. Maier , Elizabeth G. Davis , Pedro Celis
IPC分类号： G06F12/00 , G06F17/30
CPC分类号： G06F17/30433 , Y10S707/99932 , Y10S707/99942
摘要： An SQL program executor and an SOL compiler both include options for avoiding recompilations of execution plans whenever the runtime object and the compile time object referenced by an execution plan meet predefined schema similarity criteria. Thus, recompilation is sometimes avoided even though the compile time object has been altered or the run time object is not the same object as the compile time object. To enable late binding, schema information is stored in each execution plan for each object to be accessed by the execution plan. The stored schema information is a subset of the full object schema, and includes information about all the aspects of the objects to be accessed which must remain unchanged in order for the execution plan to be operable. While executing a compiled program, the SQL executor avoids recompilations of execution plans whenever the runtime object and the compile time object referenced by an execution plan meet predefined schema similarity criteria. When a recompilation of an SQL program is required, only the execution plans which do not meet the schema similarity criteria are recompiled if the compiled program has been assigned appropriate runtime parameters. The late binding features of the SQL executor also enable a compiled program to access objects distinct from the objects referenced by the program at compile time. Similarly, the SQL compiler includes the ability to recompile only those execution plans which do not meet the schema similarity criteria and thus are inoperable.
摘要翻译： SQL程序执行器和SOL编译器都包括用于在运行时对象和执行计划引用的编译时对象满足预定义的模式相似性标准时避免重新编译执行计划的选项。因此，即使编译时间对象已被更改或运行时间对象与编译时间对象不是相同的对象，有时也可避免重新编译。为了启用后期绑定，模式信息存储在执行计划要访问的每个对象的每个执行计划中。存储的模式信息是完整对象模式的一个子集，并且包括关于要访问的对象的所有方面的信息，这些信息必须保持不变，以便执行计划可操作。在执行编译程序时，只要执行计划引用的运行时对象和编译时对象都符合预定义的模式相似性标准，SQL执行程序就会避免重新编译执行计划。当需要重新编译SQL程序时，如果已编译的程序已分配适当的运行时参数，则仅重新编译不符合模式相似性标准的执行计划。 SQL执行程序的后期绑定功能还使得编译的程序能够在编译时访问与程序引用的对象不同的对象。类似地，SQL编译器包括仅重新编译那些不符合模式相似性标准因而无法操作的执行计划的能力。

8. 发明授权

US09266838B2 Substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs as histone demethylase inhibitors 有权
公开(公告)号：US09266838B2
公开(公告)日：2016-02-23
申请号：US13921895
申请日：2013-06-19
申请人： Hariprasad Vankayalapati , Venkataswamy Sorna , Steven L. Warner , Bret Stephens , David J. Bearss , Sunil Sharma
发明人： Hariprasad Vankayalapati , Venkataswamy Sorna , Steven L. Warner , Bret Stephens , David J. Bearss , Sunil Sharma
IPC分类号： C07D231/12 , C07C251/86 , C07C311/16 , C07C311/37 , C07D207/48 , C07D213/61 , C07D213/71 , C07D213/53 , C07D213/81 , C07D295/26
CPC分类号： A61K31/54 , A61K31/18 , A61K31/40 , A61K31/4453 , A61K31/495 , A61K31/5375 , A61K31/5377 , C07C251/86 , C07C311/16 , C07C311/37 , C07D207/48 , C07D213/53 , C07D213/61 , C07D213/71 , C07D213/81 , C07D231/12 , C07D295/26
摘要： In one aspect, the invention relates to substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

9. 发明申请

US20130059847A1 SUBSTITUTED N-(3-(PYRIMIDIN-4-YL)PHENYL)ACRYLAMIDE ANALOGS AS TYROSINE RECEPTOR KINASE BTK INHIBITORS 有权
公开(公告)号：US20130059847A1
公开(公告)日：2013-03-07
申请号：US13436963
申请日：2012-04-01
申请人： David J. Bearss , Hariprasad Vankayalapati , Venkataswamy Sorna , Steven L. Warner , Sunil Sharma
发明人： David J. Bearss , Hariprasad Vankayalapati , Venkataswamy Sorna , Steven L. Warner , Sunil Sharma
IPC分类号： C07D487/04 , A61K31/519 , C07D239/42 , C07D413/12 , C07D403/12 , A61P35/00 , A61P35/02 , A61P29/00 , A61P19/02 , A61K31/506 , A61K31/5377 , C07D239/30
CPC分类号： C07D239/48 , C07D239/30 , C07D239/42 , C07D471/04 , C07D487/04
摘要： In one aspect, the invention relates to substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the BTK kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the BTK kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

10. 发明授权

US08360714B2 Gas turbine engine front center body architecture 有权
标题翻译：燃气涡轮发动机前中心体结构
公开(公告)号：US08360714B2
公开(公告)日：2013-01-29
申请号：US13407916
申请日：2012-02-29
申请人： John R. Otto , Brian P. Cigal , Sunil Sharma
发明人： John R. Otto , Brian P. Cigal , Sunil Sharma
IPC分类号： F01D25/28
CPC分类号： F01D25/28 , F01D25/16 , F01D25/285 , F02C3/107 , F05D2230/70 , F05D2230/72 , F05D2230/80 , Y02T50/671 , Y10T29/49229
摘要： A gas turbine engine includes a central body support that provides an inner annular wall for a core flow path. The central body support includes first splines. A geared architecture interconnects a spool and a fan rotatable about an axis. A flex support interconnects the geared architecture to the central body support. The flex support includes second splines that intermesh with the first splines for transferring torque there between.
摘要翻译：燃气涡轮发动机包括中心主体支撑件，其提供用于芯流动路径的内部环形壁。中心体支架包括第一个花键。齿轮架构将线轴和绕轴旋转的风扇相互连接。柔性支撑将齿轮架构与中心体支撑相互连接。柔性支撑件包括与第一花键相互啮合的第二花键，用于在其间传递扭矩。

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