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1. 发明授权

US09773307B2 Quantification and imaging methods and system of the echo texture feature 有权
公开(公告)号：US09773307B2
公开(公告)日：2017-09-26
申请号：US14558298
申请日：2014-12-02
申请人： AmCad BioMed Corporation
发明人： King-Jen Chang , Argon Chen , Chiung-Nein Chen , Kuen Yuan Chen , Yu-Hsin Wang , Kuo-Chen Huang
IPC分类号： G06T7/40 , G06T7/00 , G06T7/41
CPC分类号： G06T7/0012 , G06T7/41 , G06T2207/10132 , G06T2207/20104 , G06T2207/30096
摘要： The present invention provides quantification and imaging methods and a system of the echo-texture feature, comprising: obtaining an ultrasonic image; calculating all the pixel values in a selected ROI of the ultrasonic image to obtain a regional standard deviation; excluding pixels with a pixel value smaller than a multiple of the regional standard deviation in the selected ROI; counting a set of pixels centered around a Nth pixel to gather a Nth local mean, a Nth local variance and a Nth local coefficient of variance corresponding the set of pixel values, wherein N is from 1 to the number of the pixels remaining in the selected ROI; and obtaining an echo-texture index according to the local means, the local variances, or the local coefficient of variances. The imaging of echo texture which shows the echo texture distribution of the selected ROI with a color scale changing continuously from red to blue is also included. A parameter is provided to adjust the visualization enhancement of the echo texture.

2. 发明申请

US20150086094A1 ECHOGENICITY QUANTIFICATION METHOD AND CALIBRATION METHOD FOR ULTRASONIC DEVICE USING ECHOGENICITY INDEX 审中-公开
标题翻译：使用生殖指数的超声波装置的生物量化方法和校准方法
公开(公告)号：US20150086094A1
公开(公告)日：2015-03-26
申请号：US14557013
申请日：2014-12-01
申请人： AmCad BioMed Corporation
发明人： King-Jen Chang , Chiung-Nein Chen , Ming-Hsun Wu , Argon Chen , Yu-Hsin Wang , Kuo-Chen Huang
IPC分类号： G06T7/40
CPC分类号： G06T7/0012 , G06T7/41 , G06T2207/10132 , G06T2207/20104 , G06T2207/30096
摘要： An echogenicity quantification method and a calibration method for ultrasonic device using echogenicity index are disclosed. The method includes: receiving an ultrasound image which comprises a plurality of grayscale pixels; choosing a region of interest (ROI); calculating the values of the grayscale pixels in ROI to obtain average value and standard deviation; excluding pixels in ROI with the grayscale value smaller than the sum of the minimum value in the grayscale image and the product of a first scaling factor and the standard deviation, and larger than the sum of the average value and the product of a second scaling factor and the standard deviation; averaging the values of the remaining grayscale pixels in ROI to obtain an average value of interest; choosing a reference region; averaging the values of the remaining grayscale pixels in the reference region to obtain an average value of reference; and calculating the difference between the average value of interest and the average value of reference to obtain an echogenicity index.
摘要翻译：公开了使用回波指数的超声波装置的回波定量方法和校准方法。该方法包括：接收包括多个灰度像素的超声图像; 选择感兴趣的区域（ROI）; 计算ROI中灰度像素的值以获得平均值和标准偏差; 排除ROI中的像素，灰度值小于灰度图像中的最小值和第一缩放因子与标准偏差的乘积之和，并且大于平均值与第二比例因子的乘积之和和标准差; 对ROI中的剩余灰度像素的值进行平均以获得感兴趣的平均值; 选择参考区域; 对参考区域中的剩余灰度像素的值进行平均以获得参考的平均值; 并计算感兴趣的平均值与参考的平均值之间的差以获得回波指数。

3. 发明授权

US10105123B2 Analysis methods of ultrasound echo signals based on statistics of scatterer distributions 有权
公开(公告)号：US10105123B2
公开(公告)日：2018-10-23
申请号：US14962844
申请日：2015-12-08
申请人： AmCad BioMed Corporation
发明人： Argon Chen , Yu-Hsin Wang , Kuo-Chen Huang , Jia-Jiun Chen
IPC分类号： A61B8/08 , A61B8/14 , A61B8/00
摘要： The invention provides an analysis method of ultrasound echo signals based on statistics of scatterer distributions. The beginning of steps, choosing an ultrasound echo signal as a center, and calculating the signal image values of all ultrasound echo signals within a window block in an ultrasound image data to obtain an ultrasound scatterer value. Then, choosing another ultrasound echo signal as the center to repeat the previous steps until all of ultrasound echo signals may be calculated. The interval between each of ultrasound echo signal is one point distance. Finally, to output an ultrasound scatterer mode image with all ultrasound scatterer values by utilizing color scale. The ultrasound scatterer mode image can assist doctor to confirm the relative region of lesion in a target organ.

4. 发明授权

US10249037B2 Echogenicity quantification method and calibration method for ultrasonic device using echogenicity index 有权
公开(公告)号：US10249037B2
公开(公告)日：2019-04-02
申请号：US14557013
申请日：2014-12-01
申请人： AmCad BioMed Corporation
发明人： King-Jen Chang , Chiung-Nein Chen , Ming-Hsun Wu , Argon Chen , Yu-Hsin Wang , Kuo-Chen Huang
IPC分类号： G06T7/00 , G06T7/41
摘要： An echogenicity quantification method and a calibration method for ultrasonic device using echogenicity index are disclosed. The method includes: receiving an ultrasound image which comprises a plurality of grayscale pixels; choosing a region of interest (ROI); calculating the values of the grayscale pixels in ROI to obtain average value and standard deviation; excluding pixels in ROI with the grayscale value smaller than the sum of the minimum value in the grayscale image and the product of a first scaling factor and the standard deviation, and larger than the sum of the average value and the product of a second scaling factor and the standard deviation; averaging the values of the remaining grayscale pixels in ROI to obtain an average value of interest; choosing a reference region; averaging the values of the remaining grayscale pixels in the reference region to obtain an average value of reference; and calculating the difference between the average value of interest and the average value of reference to obtain an echogenicity index.

5. 发明授权

US09412167B2 Acceleration and enhancement methods and system for ultrasound scatterer structure visualization 有权
标题翻译：超声散射体结构可视化的加速和增强方法与系统
公开(公告)号：US09412167B2
公开(公告)日：2016-08-09
申请号：US14704257
申请日：2015-05-05
申请人： AmCad BioMed Corporation
发明人： Po-Hsiang Tsui , Ming-Chih Ho , Chiung-Nein Chen , Argon Chen , Jia-Jiun Chen , Yu-Hsin Wang , Kuo-Chen Huang
IPC分类号： G06K9/00 , G06T7/00 , A61B8/14 , A61B8/00
CPC分类号： G06T7/0034 , A61B8/14 , A61B8/461 , G01S7/52047 , G01S15/8977 , G06T7/0014 , G06T2207/10132 , G06T2207/30024
摘要： The present invention provides an acceleration and enhancement methods for ultrasound scatterer structure visualization. The method includes: obtaining an ultrasonic image, calculating all values of the ultrasonic signal points in each mth window centered at a nth signal point to obtain a plurality of original statistical values anxm, obtaining a plurality of mth statistical values by averaging value of original statistical values in the same window, calculating a plurality of mth weighting values based on the statistical values by different weighting formulas, multiplying each weighting value with the original statistical values corresponding to the various size of windows, summing up to obtain an ultrasound structure scatterer value of the nth ultrasonic signal point, and generating an ultrasound scatterer structure image based on a matrix of the ultrasound scatterer values. The present invention further combined interpolation method can reduce the computation time and retain the 80% accuracy.
摘要翻译：本发明提供了一种用于超声散射体结构可视化的加速和增强方法。该方法包括：获得超声波图像，计算以第n个信号点为中心的第m个窗口中的超声信号点的所有值，以获得多个原始统计值焦虑，通过平均原始统计值获得多个第m个统计值在相同的窗口中，通过不同的加权公式基于统计值计算多个第m个加权值，将每个加权值与对应于各种尺寸的窗口的原始统计值相乘，求和获得超声波结构散射体值第n超声信号点，并且基于超声波散射体值的矩阵生成超声波散射体结构图像。本发明进一步组合插值方法可以减少计算时间并保持80％的精度。

6. 发明申请

US20160133020A1 ACCELERATION AND ENHANCEMENT METHODS AND SYSTEM FOR ULTRASOUND SCATTERER STRUCTURE VISUALIZATION 有权
标题翻译：超声波扫描仪结构可视化的加速和增强方法与系统
公开(公告)号：US20160133020A1
公开(公告)日：2016-05-12
申请号：US14704257
申请日：2015-05-05
申请人： AmCad BioMed Corporation
发明人： Po-Hsiang Tsui , Ming-Chih Ho , Chiung-Nein Chen , Argon Chen , Jia-Jiun Chen , Yu-Hsin Wang , Kuo-Chen Huang
IPC分类号： G06T7/00 , A61B8/00 , A61B8/14
CPC分类号： G06T7/0034 , A61B8/14 , A61B8/461 , G01S7/52047 , G01S15/8977 , G06T7/0014 , G06T2207/10132 , G06T2207/30024
摘要： The present invention provides an acceleration and enhancement methods for ultrasound scatterer structure visualization. The method includes: obtaining an ultrasonic image, calculating all values of the ultrasonic signal points in each mth window centered at a nth signal point to obtain a plurality of original statistical values anxm, obtaining a plurality of mth statistical values by averaging value of original statistical values in the same window, calculating a plurality of mth weighting values based on the statistical values by different weighting formulas, multiplying each weighting value with the original statistical values corresponding to the various size of windows, summing up to obtain an ultrasound structure scatterer value of the nth ultrasonic signal point, and generating an ultrasound scatterer structure image based on a matrix of the ultrasound scatterer values. The present invention further combined interpolation method can reduce the computation time and retain the 80% accuracy.
摘要翻译：本发明提供了一种用于超声散射体结构可视化的加速和增强方法。该方法包括：获得超声波图像，计算以第n个信号点为中心的第m个窗口中的超声信号点的所有值，以获得多个原始统计值焦虑，通过平均原始统计值获得多个第m个统计值在相同的窗口中，通过不同的加权公式基于统计值计算多个第m个加权值，将每个加权值与对应于各种尺寸的窗口的原始统计值相乘，求和获得超声波结构散射体值第n超声信号点，并且基于超声波散射体值的矩阵生成超声波散射体结构图像。本发明进一步组合插值方法可以减少计算时间并保持80％的精度。

7. 发明申请

US20150086095A1 QUANTIFICATION AND IMAGING METHODS AND SYSTEM OF THE ECHO TEXTURE FEATURE 有权
标题翻译： ECHO纹理特征的量化和成像方法与系统
公开(公告)号：US20150086095A1
公开(公告)日：2015-03-26
申请号：US14558298
申请日：2014-12-02
申请人： AmCad BioMed Corporation
发明人： King-Jen Chang , Argon Chen , Chiung-Nein Chen , Kuen Yuan Chen , Yu-Hsin Wang , Kuo-Chen Huang
IPC分类号： G06T7/40
CPC分类号： G06T7/0012 , G06T7/41 , G06T2207/10132 , G06T2207/20104 , G06T2207/30096
摘要： The present invention provides quantification and imaging methods and a system of the echo-texture feature, comprising: obtaining an ultrasonic image; calculating all the pixel values in a selected ROI of the ultrasonic image to obtain a regional standard deviation; excluding pixels with a pixel value smaller than a multiple of the regional standard deviation in the selected ROI; counting a set of pixels centered around a Nth pixel to gather a Nth local mean, a Nth local variance and a Nth local coefficient of variance corresponding the set of pixel values, wherein N is from 1 to the number of the pixels remaining in the selected ROI; and obtaining an echo-texture index according to the local means, the local variances, or the local coefficient of variances. The imaging of echo texture which shows the echo texture distribution of the selected ROI with a color scale changing continuously from red to blue is also included. A parameter is provided to adjust the visualization enhancement of the echo texture.
摘要翻译：本发明提供了量化和成像方法以及回波纹理特征的系统，包括：获得超声波图像; 计算超声图像的所选ROI中的所有像素值以获得区域标准偏差; 排除像素值小于选择的ROI中的区域标准偏差的倍数的像素; 对以第n个像素为中心的一组像素进行计数，以收集第N个局部平均值，第N个局部方差和第N个局部方差系数对应于像素值集合，其中N为从所选择的像素剩余的像素数投资回报率并根据本地方法，局部方差或局部方差系数获得回波纹理索引。还包括回波纹理的成像，其显示所选择的ROI的回波纹理分布，其颜色标度连续地从红色变为蓝色。提供了一个参数来调整回波纹理的可视化增强。

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