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1. 发明申请

US20120071538A1 PHARMACEUTICAL FORMULATONS 有权
标题翻译：药用配方
公开(公告)号：US20120071538A1
公开(公告)日：2012-03-22
申请号：US13110619
申请日：2011-05-18
申请人： Anders Nilsson , Hans Lindner , JØRGEN Wittendorff
发明人： Anders Nilsson , Hans Lindner , JØRGEN Wittendorff
IPC分类号： A61K31/40 , A61P3/10 , A61P13/00
CPC分类号： A61K38/11 , A61K9/0056 , A61K9/2013 , A61K9/2018 , A61K9/2063 , A61K9/2095 , A61K38/08 , A61K38/12 , A61K47/12 , A61K47/26 , A61K47/42
摘要： Good bioavailability of desmopressin can be obtained by means of an orodispersible pharmaceutical dosage form. Preferred dosage forms comprise desmopressin and an open matrix network which is an inert water-soluble or water-dispersible carrier material. Desmopressin formulated in this way is useful for voiding postponement, or the treatment or prevention of incontinence, primary noctural enuresis (PNE), nocturia or central diabetes insipidus. Peptides other than desmopressin can also be formulated in this way.
摘要翻译：去氨加压素的良好生物利用度可以通过可分散的药物剂型获得。优选的剂型包括去氨加压素和作为惰性水溶性或水分散性载体材料的开放性基质网络。以这种方式配制的去氨加压素可用于排尿延迟或治疗或预防失禁，原发性眼睑遗尿症（PNE），夜尿症或中枢性尿崩症。除了去氨加压素之外的肽也可以以这种方式配制。

2. 发明授权

US07947654B2 Pharmaceutical formulations 有权
标题翻译：药物制剂
公开(公告)号：US07947654B2
公开(公告)日：2011-05-24
申请号：US12487116
申请日：2009-06-18
申请人： Anders Nilsson , Hans Lindner , Jørgen Wittendorff
发明人： Anders Nilsson , Hans Lindner , Jørgen Wittendorff
IPC分类号： A61K38/12
CPC分类号： A61K38/11 , A61K9/0056 , A61K9/2013 , A61K9/2018 , A61K9/2063 , A61K9/2095 , A61K38/08 , A61K38/12 , A61K47/12 , A61K47/26 , A61K47/42
摘要： Good bioavailability of desmopressin can be obtained by means of an orodispersible pharmaceutical dosage form. Preferred dosage forms comprise desmopressin and an open matrix network which is an inert water-soluble or water-dispersible carrier material. Desmopressin formulated in this way is useful for voiding postponement, or the treatment or prevention of incontinence, primary noctural enuresis (PNE), nocturia or central diabetes insipidus. Peptides other than desmopressin can also be formulated in this way.
摘要翻译：去氨加压素的良好生物利用度可以通过可分散的药物剂型获得。优选的剂型包括去氨加压素和作为惰性水溶性或水分散性载体材料的开放性基质网络。以这种方式配制的去氨加压素可用于排尿延迟或治疗或预防失禁，原发性眼睑遗尿症（PNE），夜尿症或中枢性尿崩症。除了去氨加压素之外的肽也可以以这种方式配制。

3. 发明授权

US08802624B2 Methods of treatment using orodispersible desmopressin pharmaceutical formulations 有权
标题翻译：使用分散性去氨加压素药物制剂的治疗方法
公开(公告)号：US08802624B2
公开(公告)日：2014-08-12
申请号：US13110619
申请日：2011-05-18
申请人： Anders Nilsson , Hans Lindner , Jørgen Wittendorff
发明人： Anders Nilsson , Hans Lindner , Jørgen Wittendorff
IPC分类号： A61K9/20 , A61K38/08
CPC分类号： A61K38/11 , A61K9/0056 , A61K9/2013 , A61K9/2018 , A61K9/2063 , A61K9/2095 , A61K38/08 , A61K38/12 , A61K47/12 , A61K47/26 , A61K47/42
摘要： Described herein are methods of treating diseases or conditions such as incontinence, primary nocturnal enuresis (PNE), nocturia, and central diabetes insipidus, by administering desmopressin acetate in an orodispersiblc solid dosage form that disintegrates in the mouth within 10 seconds and includes an amount of desmopressin acetate, measured as the free base, of from 10 to 600 μg.
摘要翻译：本文描述的是通过在10秒内通过在口腔中分解的直径为分散的固体剂型施用醋酸去氨加压素来治疗疾病或病症如尿失禁，原发性夜间遗尿（PNE），夜尿症和中枢性尿崩症的方法，并且包括以游离碱计，醋酸去氨加压素为10至600μg。

4. 发明授权

US07560429B2 Orodispersible dosage forms of desmopressin acetate 有权
标题翻译：醋酸去氨加压素的分散剂剂型
公开(公告)号：US07560429B2
公开(公告)日：2009-07-14
申请号：US10513437
申请日：2003-05-07
申请人： Anders Nilsson , Hans Lindner , Jørgen Wittendorff
发明人： Anders Nilsson , Hans Lindner , Jørgen Wittendorff
IPC分类号： A61K38/12
CPC分类号： A61K38/11 , A61K9/0056 , A61K9/2013 , A61K9/2018 , A61K9/2063 , A61K9/2095 , A61K38/08 , A61K38/12 , A61K47/12 , A61K47/26 , A61K47/42
摘要： Good bioavailability of desmopressin can be obtained by means of an orodispersible pharmaceutical dosage form. Preferred dosage forms comprise desmopressin and an open matrix network which is an inert water-soluble or water-dispersible carrier material. Desmopressin formulated in this way is useful for voiding postponement, or the treatment or prevention of incontinence, primary nocturnal enuresis (PNE), nocturia or central diabetes insipidus. Peptides other than desmopressin can also be formulated in this way.
摘要翻译：去氨加压素的良好生物利用度可以通过可分散的药物剂型获得。优选的剂型包括去氨加压素和作为惰性水溶性或水分散性载体材料的开放性基质网络。以这种方式配制的去氨加压素可用于排尿延迟，治疗或预防失禁，原发性夜间遗尿症（PNE），夜尿症或中枢性尿崩症。除了去氨加压素之外的肽也可以以这种方式配制。

5. 发明申请

US20090318665A1 PHARMACEUTICAL FORMULATIONS 有权
标题翻译：药物制剂
公开(公告)号：US20090318665A1
公开(公告)日：2009-12-24
申请号：US12487116
申请日：2009-06-18
申请人： Anders Nilsson , Hans Lindner , Jorgen Wittendorff
发明人： Anders Nilsson , Hans Lindner , Jorgen Wittendorff
IPC分类号： C07K7/16
CPC分类号： A61K38/11 , A61K9/0056 , A61K9/2013 , A61K9/2018 , A61K9/2063 , A61K9/2095 , A61K38/08 , A61K38/12 , A61K47/12 , A61K47/26 , A61K47/42
摘要： Good bioavailability of desmopressin can be obtained by means of an orodispersible pharmaceutical dosage form. Preferred dosage forms comprise desmopressin and an open matrix network which is an inert water-soluble or water-dispersible carrier material. Desmopressin formulated in this way is useful for voiding postponement, or the treatment or prevention of incontinence, primary noctural enuresis (PNE), nocturia or central diabetes insipidus. Peptides other than desmopressin can also be formulated in this way.
摘要翻译：去氨加压素的良好生物利用度可以通过可分散的药物剂型获得。优选的剂型包括去氨加压素和作为惰性水溶性或水分散性载体材料的开放性基质网络。以这种方式配制的去氨加压素可用于排尿延迟或治疗或预防失禁，原发性眼睑遗尿症（PNE），夜尿症或中枢性尿崩症。除了去氨加压素之外的肽也可以以这种方式配制。

6. 发明授权

US09260480B2 Process for the manufacture of Degarelix and its intermediates 有权
标题翻译： Degarelix及其中间体的制造方法
公开(公告)号：US09260480B2
公开(公告)日：2016-02-16
申请号：US13881751
申请日：2011-10-26
申请人： Dipak Kalita , Mohosin Layek , Atmakuri Venkata Dhanunjaya Rao , Venkat Aravinda Potula , Vikas Gajare , Kesavan Balakumaran , Anders Nilsson , Guangcheng Jiang
发明人： Dipak Kalita , Mohosin Layek , Atmakuri Venkata Dhanunjaya Rao , Venkat Aravinda Potula , Vikas Gajare , Kesavan Balakumaran , Anders Nilsson , Guangcheng Jiang
IPC分类号： C07K7/02 , C07K7/06 , C07K7/23 , C07K7/00 , C07K7/04 , C07K1/02 , C07K1/06 , C07K1/10 , A61K38/00 , A61K38/09 , A61K38/08 , A61K38/04 , C07K5/08
CPC分类号： C07K7/06 , A61K38/00 , A61K38/04 , A61K38/08 , A61K38/09 , C07K1/02 , C07K1/026 , C07K1/06 , C07K1/10 , C07K5/08 , C07K7/00 , C07K7/04 , C07K7/23 , Y02P20/55
摘要： The present invention relates to a liquid (or solution)-phase manufacturing process for preparing the decapeptide Degareiix, its amino-protected precursor, and other useful intermediates. The invention further relates to polypeptides useful in the solution-phase manufacturing process and to the purification of Degareiix itself. The manufacturing process comprises the step of cleaving the ε-amino protecting group Pε from a Degareiix precursor according to formula {P4)(Pε)Ac-AA1-AA10-NH2 in an organic solvent comprising the precursor and a cleaving agent dissolved therein: wherein P4 is a hydroxyl-protecting group or hydrogen, preferably hydrogen.
摘要翻译：本发明涉及用于制备十肽Degareiix，其氨基保护的前体和其它有用的中间体的液体（或溶液）相制备方法。本发明进一步涉及可用于溶液相制备方法中的多肽和Degareiix本身的纯化。制备方法包括裂解“酰氨基保护基”的步骤。由含有前体的有机溶剂中的根据式{P4）（P＆amp; Ac）AA-AA10-NH 2的去角闪ix前体衍生自其中P4是羟基保护基或氢，优选氢。

7. 发明申请

US20140351555A1 DIGITAL SIGNAL PROCESSOR AND METHOD FOR ADDRESSING A MEMORY IN A DIGITAL SIGNAL PROCESSOR 有权
标题翻译：数字信号处理器和用于寻址数字信号处理器中的存储器的方法
公开(公告)号：US20140351555A1
公开(公告)日：2014-11-27
申请号：US14364619
申请日：2012-11-28
申请人： Anders Nilsson , Eric Tell , Erik Alfredsson
发明人： Anders Nilsson , Eric Tell , Erik Alfredsson
IPC分类号： G06F9/30 , G06F9/35 , G06F12/06
CPC分类号： G06F9/30036 , G06F9/35 , G06F12/06 , G06F15/8061
摘要： In a digital signal processor comprising at least one vector execution unit and at least a first memory unit a third unit is arranged to provide addressing data in the form of an address vector to be used for addressing the first memory unit said third unit being connectable to the first memory unit through the on-chip network, in such a way that data provided from the third unit can be used to control the reading from and/or the writing to the first memory unit. This enables fast reading from and writing to a memory unit of data in any desired order.
摘要翻译：在包括至少一个向量执行单元和至少第一存储器单元的数字信号处理器中，第三单元被布置为提供地址向量形式的寻址数据，以用于寻址第一存储器单元，所述第三单元可连接到通过片上网络的第一存储器单元，使得从第三单元提供的数据可以用于控制对第一存储器单元的读取和/或写入。这使得能够以任何所需的顺序快速读取和写入数据的存储单元。

8. 发明授权

US08874968B1 Method and system for testing a processor designed by a configurator 有权
标题翻译：用于测试由配置器设计的处理器的方法和系统
公开(公告)号：US08874968B1
公开(公告)日：2014-10-28
申请号：US13458918
申请日：2012-04-27
申请人： Anders Nilsson , Eric Tell , Olof Kraigher
发明人： Anders Nilsson , Eric Tell , Olof Kraigher
IPC分类号： G06F11/00
CPC分类号： G06F11/3672
摘要： The present invention provides a system and method that includes a library module including a plurality of programmable components and at least one corresponding test case for each programmable component. The system also includes the configurator module coupled to the library module and accessing at least one of the plurality of programmable components and the at least one corresponding test case. The configurator module further outputs a code describing a processor for running a software-defined digital signal processor and includes the accessed programmable component and a plurality of interconnections linking the accessed programmable component. The system further includes a test case generator coupled to the configurator to output a test suite including the at least one corresponding test case for each accessed programmable component and a plurality of interconnect tests to test the plurality of interconnections linking the accessed programmable component.
摘要翻译：本发明提供一种系统和方法，该系统和方法包括一个库模块，该库模块包括多个可编程组件和至少一个对应的每个可编程组件的测试用例。该系统还包括耦合到库模块的配置器模块并且访问多个可编程组件和至少一个相应测试用例中的至少一个。配置器模块还输出描述用于运行软件定义的数字信号处理器的处理器的代码，并且包括所访问的可编程组件和链接所访问的可编程组件的多个互连。所述系统还包括耦合到所述配置器的测试用例发生器，以输出测试套件，所述测试套件包括用于每个可访问的可编程组件的所述至少一个相应的测试用例以及用于测试所述多个互连链接所访问的可编程组件的多个互连测试。

9. 发明申请

US20090123324A1 Iron-Base Alloy Containing Chromium-Tungsten Carbide And a Method Of Producing It 审中-公开
标题翻译：含有碳化钨的铁基合金及其生产方法
公开(公告)号：US20090123324A1
公开(公告)日：2009-05-14
申请号：US12256290
申请日：2008-10-22
申请人： Carl-Hakan Andersson , Mikael Andersson , Henrik Andersson , Helena Andersson , Anders Nilsson , Jan-Eric Stahl
发明人： Carl-Hakan Andersson , Mikael Andersson , Henrik Andersson , Helena Andersson , Anders Nilsson , Jan-Eric Stahl
IPC分类号： C22C38/52 , C22C38/30 , B22D25/00 , C22C30/00
CPC分类号： C22C33/08 , C22C37/06
摘要： A method and cast wear resistant component made of an alloy that includes carbon, tungsten, chromium, and cobalt with the balance essentially iron and other alloying components made using waste, surplus or worn-out cemented carbide product, such as cemented carbide cutting tool inserts. In one method, the alloy further includes silicon, manganese, nickel, titanium, and molybdenum. In practicing the method, pieces of waste, surplus or worn-out cemented carbide product having tungsten carbide (WC) are added to a cast iron alloy melt. The melt includes enough chromium to control solubility of the WC. In one method, precipitated carbide structure having chromium and carbon is produced with tungsten in the melt being substitutionally dissolved. In one implementation, tungsten is substitutionally dissolved in a lattice of the precipitated carbide structure. Carbide can be added to the melt via super inoculation. The cast wear resistant component can be a cutting tool.
摘要翻译：由合金制成的方法和铸造耐磨部件，其包括碳，钨，铬和钴，余量基本上为铁和其他使用废料，过剩或磨损的硬质合金产品制成的合金元件，例如硬质合金刀具插入件。在一种方法中，合金还包括硅，锰，镍，钛和钼。在实施该方法中，将具有碳化钨（WC）的废弃物，剩余或磨损的硬质合金产品块加入到铸铁合金熔体中。熔体包含足够的铬以控制WC的溶解度。在一种方法中，在熔融物中用钨制造具有铬和碳的沉淀碳化物结构被取代溶解。在一个实施方案中，钨被代替地溶解在沉淀的碳化物结构的晶格中。可以通过超级接种将硬质合金加入到熔体中。铸造耐磨部件可以是切削工具。

10. 发明申请

US20090064551A1 INFORMATION CARRIER 审中-公开
标题翻译：信息载体
公开(公告)号：US20090064551A1
公开(公告)日：2009-03-12
申请号：US11718660
申请日：2005-11-07
申请人： Erik Schroder , Anders Nilsson
发明人： Erik Schroder , Anders Nilsson
IPC分类号： G09F7/00
CPC分类号： G09F7/16
摘要： The method facilitates for an individual to orientate himself in a building including the installation of at least an information carrier at a location selected with regard to a configuration of the building. The information carrier includes a visual representation of at least a section of a floor of the building and at least some information associated with the building. The visual representation is a perspective view of the section of the floor.
摘要翻译：该方法有助于个人在建筑物中定向自己，包括至少在关于建筑物的配置选择的位置处安装信息载体。信息载体包括建筑物的至少一部分的视觉表示以及与建筑物相关联的至少一些信息。视觉表示是地板部分的透视图。

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