专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20220257696A1 Granular Pharmaceutical Composition 有权
公开(公告)号：US20220257696A1
公开(公告)日：2022-08-18
申请号：US17736243
申请日：2022-05-04
申请人： Astellas Pharma, Inc.
发明人： Mare Nishiura , Kenichi Ashihara , Kanehira Imai , Atsushi Muro , Tsukasa Nishikawahara
IPC分类号： A61K38/10 , A61K9/16 , A61K9/20 , A61K9/50 , A61K38/12
摘要： The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.

2. 发明申请

US20200206305A1 Granular Pharmaceutical Composition 审中-公开
公开(公告)号：US20200206305A1
公开(公告)日：2020-07-02
申请号：US16816576
申请日：2020-03-12
申请人： Astellas Pharma, Inc.
发明人： Mare Nishiura , Kenichi Ashihara , Kanehira Imai , Atsushi Muro , Tsukasa Nishikawahara
IPC分类号： A61K38/10 , A61K9/16 , A61K9/20 , A61K38/12 , A61K9/50
摘要： The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.

3. 发明申请

US20210161996A1 Granular Pharmaceutical Composition 有权
公开(公告)号：US20210161996A1
公开(公告)日：2021-06-03
申请号：US17080129
申请日：2020-10-26
申请人： Astellas Pharma, Inc.
发明人： Mare Nishiura , Kenichi Ashihara , Kanehira Imai , Atsushi Muro , Tsukasa Nishikawahara
IPC分类号： A61K38/10 , A61K9/16 , A61K38/12 , A61K9/20 , A61K9/50 , A61K9/48
摘要： The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.

4. 发明申请

US20190060395A1 Granular Pharmaceutical Composition 审中-公开
公开(公告)号：US20190060395A1
公开(公告)日：2019-02-28
申请号：US16171550
申请日：2018-10-26
申请人： Astellas Pharma, Inc.
发明人： Mare Nishiura , Kenichi Ashihara , Kanehira Imai , Atsushi Muro , Tsukasa Nishikawahara
IPC分类号： A61K38/10 , A61K38/12 , A61K9/50 , A61K9/16 , A61K9/20 , A61K9/48
摘要： The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.

5. 发明申请

US20220008501A1 Granular Pharmaceutical Composition 有权
公开(公告)号：US20220008501A1
公开(公告)日：2022-01-13
申请号：US17483378
申请日：2021-09-23
申请人： Astellas Pharma, Inc.
发明人： Mare Nishiura , Kenichi Ashihara , Kanehira Imai , Atsushi Muro , Tsukasa Nishikawahara
IPC分类号： A61K38/10 , A61K9/16 , A61K9/20 , A61K9/50 , A61K38/12
摘要： The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.

6. 发明申请

US20140242158A1 Granular Pharmaceutical Composition 审中-公开
标题翻译：颗粒药物成分
公开(公告)号：US20140242158A1
公开(公告)日：2014-08-28
申请号：US14348110
申请日：2012-09-28
申请人： Astellas Pharma, Inc.
发明人： Mare Nishiura , Kenichi Ashihara , Kanehira Imai , Atsushi Muro , Tsukasa Nishikawahara
IPC分类号： A61K9/16 , A61K9/20 , A61K9/48 , A61K38/10
CPC分类号： A61K38/10 , A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/167 , A61K9/1682 , A61K9/1694 , A61K9/2077 , A61K9/2081 , A61K9/4808 , A61K9/5026 , A61K9/5078 , A61K38/12
摘要： The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.
摘要翻译：本发明涉及一种通过以下方法包被细胞核获得的颗粒状药物组合物：（1）含有防潮功能的物质的层，和（2）含有利那洛肽，药学上可接受的盐或其水合物的药物层，（3）含有防潮功能的材料的层。另外，本发明涉及一种制造粒状药物组合物的方法，所述颗粒状药物组合物通过用（1）含有防潮功能的材料的层包被所述细胞核，（2）含有利那洛肽，药学上可接受的盐，或其水合物，和（3）含有具有防潮功能的材料的层。

7. 发明申请

US20230113303A1 Granular Pharmaceutical Composition 有权
公开(公告)号：US20230113303A1
公开(公告)日：2023-04-13
申请号：US18063216
申请日：2022-12-08
申请人： Astellas Pharma, Inc.
发明人： Mare Nishiura , Kenichi Ashihara , Kanehira Imai , Atsushi Muro , Tsukasa Nishikawahara
IPC分类号： A61K38/10 , A61K9/16 , A61K9/20 , A61K9/50 , A61K38/12
摘要： The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.

8. 发明申请

US20180185437A1 Granular Pharmaceutical Composition 审中-公开
公开(公告)号：US20180185437A1
公开(公告)日：2018-07-05
申请号：US15906786
申请日：2018-02-27
申请人： Astellas Pharma, Inc.
发明人： Mare Nishiura , Kenichi Ashihara , Kanehira Imai , Atsushi Muro , Tsukasa Nishikawahara
IPC分类号： A61K38/10 , A61K9/16
CPC分类号： A61K38/10 , A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/167 , A61K9/1682 , A61K9/1694 , A61K9/2077 , A61K9/2081 , A61K9/4808 , A61K9/5026 , A61K9/5078 , A61K38/12
摘要： The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.

9. 发明申请

US20170087206A1 Granular Pharmaceutical Composition 审中-公开
公开(公告)号：US20170087206A1
公开(公告)日：2017-03-30
申请号：US15376932
申请日：2016-12-13
申请人： Astellas Pharma, Inc.
发明人： Mare Nishiura , Kenichi Ashihara , Kanehira Imai , Atsushi Muro , Tsukasa Nishikawahara
IPC分类号： A61K38/10 , A61K9/16
CPC分类号： A61K38/10 , A61K9/1611 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1652 , A61K9/167 , A61K9/1682 , A61K9/1694 , A61K9/2077 , A61K9/2081 , A61K9/4808 , A61K9/5026 , A61K9/5078 , A61K38/12
摘要： The present invention relates to a granular pharmaceutical composition obtained by coating a nucleus with: (1) a layer containing a material having a damp-proofing function, and (2) a drug layer containing linaclotide, a pharmaceutically acceptable salt, or a hydrate thereof, and (3) a layer containing a material having a damp-proofing function. Also, the present invention relates to a method for manufacturing the granular pharmaceutical composition obtained by coating the nucleus with (1) the layer containing the material having a damp-proofing function, (2) the drug layer containing the linaclotide, the pharmaceutically acceptable salt, or the hydrate thereof, and (3) the layer containing the material having a damp-proofing function.

10. 发明授权

US09408835B2 Pharmaceutical composition for oral administration 有权
标题翻译：用于口服给药的药物组合物
公开(公告)号：US09408835B2
公开(公告)日：2016-08-09
申请号：US14779328
申请日：2014-03-28
申请人： ASTELLAS PHARMA INC.
发明人： Seiji Takae , Hiroyuki Kojima , Atsushi Sakurai , Tetsuya Tamura , Hiroaki Tasaki , Atsushi Muro
IPC分类号： A61K31/437 , A61K9/20 , A61K9/28
CPC分类号： A61K31/437 , A61K9/2013 , A61K9/2018 , A61K9/2054 , A61K9/2095 , A61K9/2806
摘要： A pharmaceutical composition containing, as the active ingredient, 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, of which the solubility in an acidic pH region is different from that in a neutral pH region, with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance, is provided. The pharmaceutical composition for oral administration of the present invention contains 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide or a pharmaceutically acceptable salt thereof, and a hydrophilic lubricant, and is useful as a pharmaceutical composition for oral administration with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance.
摘要翻译：含有作为活性成分的4 - {[（1R，2s，3S，5s，7s）-5-羟基-2-金刚烷基]氨基} -1H-吡咯并[2,3-b]吡啶-5 甲酰胺，其在酸性pH区域中的溶解度与中性pH区域的溶解度不同，具有快速的崩解性能和快速的药物溶解性以及期望良好的药物剂量依从性。本发明的口服药物组合物含有4 - {[（1R，2s，3S，5s，7s）-5-羟基-2-金刚烷基]氨基} -1H-吡咯并[2,3-b] 5-甲酰胺或其药学上可接受的盐和亲水润滑剂，并且可用作口服给药的药物组合物，其具有快速的崩解性能和快速的药物溶解性以及期望良好的药物剂量依从性。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式