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1. 发明授权

US08332024B2 Low-power analog architecture for brain-machine interfaces 有权
标题翻译：用于脑机接口的低功耗模拟架构
公开(公告)号：US08332024B2
公开(公告)日：2012-12-11
申请号：US12127497
申请日：2008-05-27
申请人： Benjamin I. Rapoport , Rahul Sarpeshkar , Woradorn Wattanapanitch , Soumyajit Mandal , Scott Arfin
发明人： Benjamin I. Rapoport , Rahul Sarpeshkar , Woradorn Wattanapanitch , Soumyajit Mandal , Scott Arfin
IPC分类号： A61B5/04 , H03F3/45
CPC分类号： G06F1/32 , A61B5/0031 , A61B5/04001 , A61B5/7232 , A61F2/72 , A61N1/3605 , A61N1/3727 , A61N1/37276 , G06F3/015 , H03F3/2176 , H03F3/45192
摘要： An ultra-low-power circuit for wireless neural recording and stimulation is provided. The circuit includes a neural amplifier with adaptive power biasing for use in multi-electrode arrays and a decoding and/or learning architecture. An impedance-modulation telemetry system provides low-power data telemetry. Also, the circuit includes a wireless link for efficient power transfer, and at least one circuit for wireless stimulation of neurons.
摘要翻译：提供了一种用于无线神经记录和刺激的超低功率电路。该电路包括具有用于多电极阵列的自适应功率偏置的神经放大器以及解码和/或学习架构。阻抗调制遥测系统提供低功耗数据遥测。此外，电路包括用于有效功率传输的无线链路，以及用于神经元的无线刺激的至少一个电路。

2. 发明申请

US20080294062A1 LOW-POWER ANALOG ARCHITECTURE FOR BRAIN-MACHINE INTERFACES 有权
标题翻译：用于脑机接口的低功耗模拟架构
公开(公告)号：US20080294062A1
公开(公告)日：2008-11-27
申请号：US12127497
申请日：2008-05-27
申请人： Benjamin I. Rapoport , Rahul Sarpeshkar , Woradorn Wattanapanitch , Soumyajit Mandal , Scott Arfin
发明人： Benjamin I. Rapoport , Rahul Sarpeshkar , Woradorn Wattanapanitch , Soumyajit Mandal , Scott Arfin
IPC分类号： A61B5/0478 , A61B18/14
CPC分类号： G06F1/32 , A61B5/0031 , A61B5/04001 , A61B5/7232 , A61F2/72 , A61N1/3605 , A61N1/3727 , A61N1/37276 , G06F3/015 , H03F3/2176 , H03F3/45192
摘要： An ultra-low-power circuit for wireless neural recording and stimulation is provided. The circuit includes a neural amplifier with adaptive power biasing for use in multi-electrode arrays and a decoding and/or learning architecture. An impedance-modulation telemetry system provides low-power data telemetry. Also, the circuit includes a wireless link for efficient power transfer, and at least one circuit for wireless stimulation of neurons.
摘要翻译：提供了一种用于无线神经记录和刺激的超低功率电路。该电路包括具有用于多电极阵列的自适应功率偏置的神经放大器以及解码和/或学习架构。阻抗调制遥测系统提供低功耗数据遥测。此外，电路包括用于有效功率传输的无线链路，以及用于神经元的无线刺激的至少一个电路。

3. 发明授权

US08352385B2 Low-power analog-circuit architecture for decoding neural signals 有权
标题翻译：用于解码神经信号的低功耗模拟电路架构
公开(公告)号：US08352385B2
公开(公告)日：2013-01-08
申请号：US12127380
申请日：2008-05-27
申请人： Benjamin I. Rapoport , Rahul Sarpeshkar , Woradorn Wattanapanitch
发明人： Benjamin I. Rapoport , Rahul Sarpeshkar , Woradorn Wattanapanitch
IPC分类号： G06F15/18
CPC分类号： A61B5/04001 , G06F3/015 , G06K9/00536
摘要： A microchip for performing a neural decoding algorithm is provided. The microchip is implemented using ultra-low power electronics. Also, the microchip includes a tunable neural decodable filter implemented using a plurality of amplifiers, a plurality of parameter learning filters, a multiplier, a gain and time-constant biasing circuits; and analog memory. The microchip, in a training mode, learns to perform an optimized translation of a raw neural signal received from a population of cortical neurons into motor control parameters. The optimization being based on a modified gradient descent least square algorithm wherein update for a given parameter in a filter is proportional to an averaged product of an error in the final output that the filter affects and a filtered version of its input. The microchip, in an operational mode, issues commands to controlling a device using learned mappings.
摘要翻译：提供了一种用于执行神经解码算法的微芯片。微芯片采用超低功耗电子器件实现。此外，微芯片包括使用多个放大器实现的可调谐神经可解码滤波器，多个参数学习滤波器，乘法器，增益和时间常数偏置电路; 和模拟记忆。在训练模式下，微芯片学习了将从皮质神经元群体接收的原始神经信号转化为电动机控制参数的优化翻译。该优化基于修正的梯度下降最小二乘算法，其中过滤器中的给定参数的更新与滤波器影响的最终输出中的误差和其输入的滤波版本的平均乘积成比例。在操作模式下，微芯片发出使用学习映射控制设备的命令。

4. 发明申请

US20080294579A1 LOW-POWER ANALOG-CIRCUIT ARCHITECTURE FOR DECODING NEURAL SIGNALS 有权
标题翻译：用于解码神经信号的低功耗模拟电路架构
公开(公告)号：US20080294579A1
公开(公告)日：2008-11-27
申请号：US12127380
申请日：2008-05-27
申请人： Benjamin I. Rapoport , Rahul Sarpeshkar , Woradorn Wattanapanitch
发明人： Benjamin I. Rapoport , Rahul Sarpeshkar , Woradorn Wattanapanitch
IPC分类号： G06F15/18
CPC分类号： A61B5/04001 , G06F3/015 , G06K9/00536
摘要： A microchip for performing a neural decoding algorithm is provided. The microchip is implemented using ultra-low power electronics. Also, the microchip includes a tunable neural decodable filter implemented using a plurality of amplifiers, a plurality of parameter learning filters, a multiplier, a gain and time-constant biasing circuits; and analog memory. The microchip, in a training mode, learns to perform an optimized translation of a raw neural signal received from a population of cortical neurons into motor control parameters. The optimization being based on a modified gradient descent least square algorithm wherein update for a given parameter in a filter is proportional to an averaged product of an error in the final output that the filter affects and a filtered version of its input. The microchip, in an operational mode, issues commands to controlling a device using learned mappings.
摘要翻译：提供了一种用于执行神经解码算法的微芯片。微芯片采用超低功耗电子器件实现。此外，微芯片包括使用多个放大器实现的可调谐神经可解码滤波器，多个参数学习滤波器，乘法器，增益和时间常数偏置电路; 和模拟记忆。在训练模式下，微芯片学习了将从皮质神经元群体接收的原始神经信号转化为电动机控制参数的优化翻译。该优化基于修正的梯度下降最小二乘算法，其中过滤器中给定参数的更新与滤波器影响的最终输出中的误差和其输入的滤波版本的平均乘积成比例。在操作模式下，微芯片发出使用学习映射控制设备的命令。

5. 发明授权

US08200325B2 Micropower neural amplifier with adaptive input-referred noise 有权
标题翻译：具有自适应输入参考噪声的微功率神经放大器
公开(公告)号：US08200325B2
公开(公告)日：2012-06-12
申请号：US12127475
申请日：2008-05-27
申请人： Rahul Sarpeshkar , Benjamin I. Rapoport , Woradorn Wattanapanitch
发明人： Rahul Sarpeshkar , Benjamin I. Rapoport , Woradorn Wattanapanitch
IPC分类号： A61B5/04 , H03F3/45
CPC分类号： H03F1/0266 , H03F1/26 , H03F3/45192
摘要： A micropower neural amplifier with adaptive power biasing for use in multi-electrode arrays is provided. The micropower neural amplifier includes a low noise gain stage. The low noise gain stage is implemented using an amplifier and pseudoresistor elements.
摘要翻译：提供了一种用于多电极阵列的具有自适应功率偏置的微功率神经放大器。微功率神经放大器包括低噪声增益级。低噪声增益级使用放大器和伪电阻元件实现。

6. 发明申请

US20080290944A1 MICROPOWER NEURAL AMPLIFIER WITH ADAPTIVE INPUT-REFERRED NOISE 有权
标题翻译：具有自适应输入提示噪声的麦克风神经放大器
公开(公告)号：US20080290944A1
公开(公告)日：2008-11-27
申请号：US12127475
申请日：2008-05-27
申请人： Rahul Sarpeshkar , Benjamin I. Rapoport , Woradorn Wattanapanitch
发明人： Rahul Sarpeshkar , Benjamin I. Rapoport , Woradorn Wattanapanitch
IPC分类号： H03F3/45
CPC分类号： H03F1/0266 , H03F1/26 , H03F3/45192
摘要： A micropower neural amplifier with adaptive power biasing for use in multi-electrode arrays is provided. The micropower neural amplifier includes a low noise gain stage. The low noise gain stage is implemented using an amplifier and pseudoresistor elements.
摘要翻译：提供了一种用于多电极阵列的具有自适应功率偏置的微功率神经放大器。微功率神经放大器包括低噪声增益级。低噪声增益级使用放大器和伪电阻元件实现。

7. 发明授权

US08285523B2 Electronic system for modeling chemical reactions and biochemical processes 有权
标题翻译：用于化学反应和生化过程建模的电子系统
公开(公告)号：US08285523B2
公开(公告)日：2012-10-09
申请号：US12575291
申请日：2009-10-07
申请人： Soumyajit Mandal , Rahul Sarpeshkar
发明人： Soumyajit Mandal , Rahul Sarpeshkar
IPC分类号： G06F17/10 , G06G7/48
CPC分类号： G05B17/02 , G06F19/12 , G06F19/702 , G06G7/58
摘要： A system for modeling chemical reactions using analog or hybrid-analog-digital electronic circuits. The system exploits similarities between the kinetic rates of chemical reaction and the rates governing current flow in electronic devices such as bipolar junction transistors (BJTs) and metal oxide semiconductor field effect transistors (MOSFETs) operating at subthreshold conditions. These devices, which accurately model the stochastics of chemical processes, can be networked into large arrays to model chemical reaction networks, including biochemical reactions and genetic processes such as activation, induction, transcription, and translation.
摘要翻译：使用模拟或混合模拟数字电子电路建模化学反应的系统。该系统利用化学反应的动力学速率和控制电流器件（例如双极结型晶体管（BJT））和在亚阈值条件下工作的金属氧化物半导体场效应晶体管（MOSFET）的电流的速率之间的相似性。这些准确地模拟化学过程随机化的装置可以联网成大型阵列，以建立化学反应网络，包括生化反应和遗传过程，如激活，诱导，转录和翻译。

8. 发明申请

US20100211364A1 ELECTRONIC SYSTEM FOR MODELING CHEMICAL REACTIONS AND BIOCHEMICAL PROCESSES 有权
标题翻译：用于建立化学反应和生物化学过程的电子系统
公开(公告)号：US20100211364A1
公开(公告)日：2010-08-19
申请号：US12575291
申请日：2009-10-07
申请人： Soumyajit Mandal , Rahul Sarpeshkar
发明人： Soumyajit Mandal , Rahul Sarpeshkar
IPC分类号： G06G7/58 , G06F17/10
CPC分类号： G05B17/02 , G06F19/12 , G06F19/702 , G06G7/58
摘要： A system for modeling chemical reactions using analog or hybrid-analog-digital electronic circuits. The system exploits similarities between the kinetic rates of chemical reaction and the rates governing current flow in electronic devices such as bipolar junction transistors (BJTs) and metal oxide semiconductor field effect transistors (MOSFETs) operating at subthreshold conditions. These devices, which accurately model the stochastics of chemical processes, can networked into large array to model chemical reaction networks, including biochemical reactions and genetic processes such as activation, induction, transcription, and translation.
摘要翻译：使用模拟或混合模拟数字电子电路建模化学反应的系统。该系统利用化学反应的动力学速率和控制电流器件（例如双极结型晶体管（BJT））和在亚阈值条件下工作的金属氧化物半导体场效应晶体管（MOSFET）的电流的速率之间的相似性。这些准确地模拟化学工艺随机化的装置可以联网到大型阵列，以建立化学反应网络，包括生化反应和遗传过程如活化，诱导，转录和翻译。

9. 发明授权

US08708923B2 Wearable system for monitoring physiological signals 有权
标题翻译：用于监测生理信号的穿戴式系统
公开(公告)号：US08708923B2
公开(公告)日：2014-04-29
申请号：US12700214
申请日：2010-02-04
申请人： Lorenzo Turicchia , Soumyajit Mandal , Rahul Sarpeshkar
发明人： Lorenzo Turicchia , Soumyajit Mandal , Rahul Sarpeshkar
IPC分类号： A61B5/04
CPC分类号： A61B7/045
摘要： A wearable system for monitoring a plurality of physiological signals is provided. The wearable system includes at least one sensor producing the physiological signals associated with a patient. A processor unit receives the physiological signals from the at least one sensor. The processor unit analyzes the physiological signals to determine the occurrence of a triggered event and produces at least one output signal identifying the triggered event. A transmission unit receives the at least one output signal and prepares for transmission of the at least one output signal.
摘要翻译：提供了一种用于监测多个生理信号的可穿戴系统。可穿戴系统包括产生与患者相关联的生理信号的至少一个传感器。处理器单元接收来自至少一个传感器的生理信号。处理器单元分析生理信号以确定触发事件的发生，并产生识别触发事件的至少一个输出信号。传输单元接收所述至少一个输出信号并准备传输所述至少一个输出信号。

10. 发明申请

US20120114081A1 Architectures For Universal Or Software Radio 有权
标题翻译：通用或软件无线电架构
公开(公告)号：US20120114081A1
公开(公告)日：2012-05-10
申请号：US13352818
申请日：2012-01-18
申请人： Soumyajit Mandal , Serhii M. Zhak , Rahul Sarpeshkar
发明人： Soumyajit Mandal , Serhii M. Zhak , Rahul Sarpeshkar
IPC分类号： H04L27/06
CPC分类号： H04B1/1036 , G01R23/163
摘要： A system and technique for providing to flexible, programmable frequency estimators and spectrum analyzers that can operate over extremely large bandwidths and yet provide high spectral resolution are described. The acquisition time and hardware complexity of one technique scale as O(N), where N denotes the number of frequency bins acquired. Embodiments are disclosed in which architectures are implemented using exponentially-tapered transmission lines and filter cascades.
摘要翻译：描述了一种用于提供灵活的可编程频率估计器和频谱分析仪的系统和技术，其可以在极大的带宽上工作并且还提供高的光谱分辨率。一种技术尺度的采集时间和硬件复杂度为O（N），其中N表示获取的频率块的数量。公开了实施例，其中使用指数级锥形传输线和滤波器级联来实现架构。

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