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1. 发明申请

US20160300359A1 Determination of Enhancing Structures in an Anatomical Body Part 有权
标题翻译：解剖体部分增强结构的确定
公开(公告)号：US20160300359A1
公开(公告)日：2016-10-13
申请号：US15034485
申请日：2013-11-05
申请人： Brainlab AG
发明人： Rainer Lachner , Rowena Thomson , Christina Sladky
IPC分类号： G06T7/00 , G06T5/20 , G06T7/60 , G06T5/00
CPC分类号： G16H30/40 , G06T5/002 , G06T5/20 , G06T7/001 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/174 , G06T7/187 , G06T7/60 , G06T2207/10096 , G06T2207/20128 , G06T2207/20156 , G06T2207/20224 , G06T2207/30016 , G06T2207/30096
摘要： A data processing method for determining an enhancing structure of interest within an anatomical body part, wherein the structure of interest exhibits an enhanced signal in an image of the anatomical body part generated by a medical imaging method using a contrast agent, said method being designed to be performed by a computer and comprising a region growing algorithm.
摘要翻译：一种用于确定解剖体部分内感兴趣的增强结构的数据处理方法，其中感兴趣的结构在通过使用造影剂的医学成像方法产生的解剖体部分的图像中显示增强的信号，所述方法被设计为由计算机执行并且包括区域增长算法。

2. 发明授权

US10056158B2 Determination of enhancing structures in an anatomical body part 有权
公开(公告)号：US10056158B2
公开(公告)日：2018-08-21
申请号：US15819995
申请日：2017-11-21
申请人： Brainlab AG
发明人： Rainer Lachner , Rowena Thomson , Christina von Freyberg
IPC分类号： G06T7/187 , G06T7/11 , G16H30/40 , G06T7/136 , G06T5/00 , G06T5/20 , G06T7/00 , G06T7/60 , G06T7/174
CPC分类号： G16H30/40 , G06T5/002 , G06T5/20 , G06T7/001 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/174 , G06T7/187 , G06T7/60 , G06T2207/10096 , G06T2207/20128 , G06T2207/20156 , G06T2207/20224 , G06T2207/30016 , G06T2207/30096
摘要： A data processing method for determining an enhancing structure of interest within an anatomical body part, wherein the structure of interest exhibits an enhanced signal in an image of the anatomical body part generated by a medical imaging method using a contrast agent, said method being designed to be performed by a computer and comprising a region growing algorithm.

3. 发明授权

US09858674B2 Determination of enhancing structures in an anatomical body part 有权
公开(公告)号：US09858674B2
公开(公告)日：2018-01-02
申请号：US15034485
申请日：2013-11-05
申请人： Brainlab AG
发明人： Rainer Lachner , Rowena Thomson , Christina Sladky
IPC分类号： G06T7/187 , G06T7/11 , G06T7/00 , G06T5/00 , G06T5/20 , G06T7/60 , G06T7/174 , G06T7/136
CPC分类号： G16H30/40 , G06T5/002 , G06T5/20 , G06T7/001 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/174 , G06T7/187 , G06T7/60 , G06T2207/10096 , G06T2207/20128 , G06T2207/20156 , G06T2207/20224 , G06T2207/30016 , G06T2207/30096
摘要： A data processing method for determining an enhancing structure of interest within an anatomical body part, wherein the structure of interest exhibits an enhanced signal in an image of the anatomical body part generated by a medical imaging method using a contrast agent, said method being designed to be performed by a computer and comprising a region growing algorithm.

4. 发明申请

US20150302166A1 METHOD FOR INVERSE TRAJECTORY PLANNING 审中-公开
标题翻译：反向规划方法
公开(公告)号：US20150302166A1
公开(公告)日：2015-10-22
申请号：US14417929
申请日：2013-01-29
申请人： Brainlab AG
发明人： Rowena Thomson , Stephan Mittermeyer
IPC分类号： G06F19/00 , G06F17/10
CPC分类号： G06F17/10 , G06F19/321 , G06F19/3481 , G16H50/50
摘要： The present invention relates to a data processing method of determining a trajectory of a medical instrument to be inserted into a patient's body for treatment of a target region in the patient's body, the method being executed by a computer and comprising the following steps: a) acquiring medical image data comprising medical image information describing an image of an anatomical body part; b) acquiring target region extent data comprising target region extent information describing a spatial extent of the target region in the medical image information; c) determining, based on the target region extent data, whether the spatial extent of the target region in the medical image information comprises more than one image particle; d) if it is determined that the target region comprises more than a predetermined number of image particles, determining, based on the medical image data, image particle weight data comprising image particle weight information describing a weight describing a tissue type component of the target region assigned to each target region image particle in the target region, which component is represented at least partly by the image particle, and determining, based on the image particle weight data and the medical image data, instrument trajectory data comprising instrument trajectory information describing a trajectory of the medical instrument along which the instrument is to be inserted into the patient's body.
摘要翻译：本发明涉及一种数据处理方法，该方法用于确定插入病人体内的医疗器具的轨迹，以便对患者身体中的目标区域进行处理，所述方法由计算机执行，包括以下步骤：a）获取包括描述解剖体部分的图像的医学图像信息的医学图像数据; b）获取包括描述医学图像信息中的目标区域的空间范围的目标区域范围信息的目标区域范围数据; c）基于目标区域范围数据确定医学图像信息中的目标区域的空间范围是否包括多于一个图像粒子; d）如果确定所述目标区域包含多于预定数量的图像粒子，则基于所述医学图像数据确定包括描述描述所述目标区域的组织类型分量的权重的图像粒子量信息的图像粒子数量数据分配给目标区域中的每个目标区域图像粒子，该分量至少部分地由图像粒子表示，并且基于图像粒子重量数据和医学图像数据确定包括描述轨迹的仪器轨迹信息的仪器轨迹数据的仪器沿着仪器插入患者身体。

5. 发明申请

US20140058747A1 METHOD FOR OPTIMISING LOCAL DRUG DELIVERY 有权
标题翻译：用于优化局部药物递送的方法
公开(公告)号：US20140058747A1
公开(公告)日：2014-02-27
申请号：US14113308
申请日：2011-05-11
申请人： Brainlab AG
发明人： Rowena Thomson , Stephan Mittermeyer
IPC分类号： G06F19/00
CPC分类号： G06F19/3468 , G06F19/00 , G16H50/20
摘要： The present invention relates to a data processing method for determining an infusion location in an anatomical region of interest of a patient's body for infusing a medical substance, the method being executed by a computer and comprising steps of: a) acquiring permeability data comprising information about the permeability of anatomical vessels in the body; b) acquiring body vessels set data comprising information about a body vessel set, wherein the body vessel set represents a set of at least one anatomical body vessel in the patient's body and wherein the body vessel set data comprises information about the spatial structure of the at least one body vessel; c) acquiring coverage condition data comprising information about a predetermined coverage of a target region with the medical substance; d) determining, for a plurality of candidate infusion locations, candidate coverage data comprising information about a candidate coverage of a target region with the medical substance based on the permeability data, the body vessel set data and the coverage condition data; e) determining infusion location data comprising information about the infusion location based on the permeability data, the body vessel set data and the coverage condition data.
摘要翻译：本发明涉及一种数据处理方法，用于确定患者身体感兴趣的解剖学区域中用于注射医疗物质的输注位置，该方法由计算机执行，该方法包括以下步骤：a）获取包含关于解剖血管在体内的渗透性; b）获取身体容器设置包括关于身体血管集合的信息的数据，其中所述体容器组表示患者身体中的一组至少一个解剖体体血管，并且其中所述身体血管设置数据包括关于所述患者的空间结构的信息至少一个身体血管; c）获取覆盖条件数据，所述覆盖条件数据包括关于所述医疗物质的目标区域的预定覆盖范围的信息; d）针对多个候选输注位置，基于所述渗透率数据，所述身体血管集合数据和所述覆盖条件数据，确定包括关于所述医疗物质的目标区域的候选覆盖度的信息的候选覆盖数据; e）基于渗透性数据，身体血管集数据和覆盖条件数据确定包括关于输注位置的信息的输注位置数据。

6. 发明申请

US20170056617A1 AGENT DELIVERY CATHETER 有权
标题翻译：代理商送货上门
公开(公告)号：US20170056617A1
公开(公告)日：2017-03-02
申请号：US15120307
申请日：2014-02-20
申请人： Brainlab AG
发明人： Rowena Thomson , Martin Rube , Stephan Mittermeyer
IPC分类号： A61M25/00 , A61M25/04 , A61M25/01
CPC分类号： A61M25/008 , A61M25/002 , A61M25/0102 , A61M25/0108 , A61M25/0127 , A61M25/04 , A61M2025/0042 , A61M2205/0211 , A61M2210/0693
摘要： The invention relates to an agent delivery catheter, comprising a first hollow tube and a second hollow tube 2 which protrudes from a distal opening of the first hollow tube 1 and defines an agent delivery lumen 3 extending along the entire length of the catheter, wherein: the distal end of the first tube 1 is coupled to the second tube 2 to form an annular cavity 4 between the first tube 1 and the second tube 2, the annular cavity 4 being configured to accommodate a retractable stylet shaft 5; a ceramic member 6 which is disposed at the distal end of the first tube 1, in particular distally with respect to the distal opening of the first tube 1, encompasses the second tube 2 and couples the first tube 1 to the second tube 2, in particular via a third hollow tube 23 which encompasses the first tube 1 and the ceramic member 6; and a protective shrink-fit tube 7 is disposed radially on the outside of the ceramic member 6 and extends over at least the length of the ceramic member 6. Another aspect of the invention relates to an agent delivery system comprising such a catheter and a stylet which comprises a handle portion 15 and a ceramic shaft 5 which is configured to be accommodated within the annular cavity 4 of said catheter, wherein a shrink-fit tube 6 is disposed radially on the outside of the ceramic shaft 5 and in particular extends over at least the length of the ceramic shaft 5.
摘要翻译：本发明涉及一种药剂递送导管，其包括第一中空管和从第一中空管1的远侧开口突出的第二中空管2，并且限定沿导管的整个长度延伸的药剂输送腔3，其中：第一管1的远端联接到第二管2，以在第一管1和第二管2之间形成环形空腔4，环形空腔4构造成容纳可伸缩的探针轴5; 设置在第一管1的远端，特别是相对于第一管1的远端开口的远端的陶瓷构件6包围第二管2，并将第一管1连接到第二管2，以特别是通过包围第一管1和陶瓷构件6的第三中空管23; 并且保护性收缩配合管7径向设置在陶瓷构件6的外侧上，并延伸至陶瓷构件6的至少长度。本发明的另一方面涉及一种包括这种导管和探针其包括手柄部分15和陶瓷轴5，其被构造成容纳在所述导管的环形空腔4内，其中收缩配合管6径向设置在陶瓷轴5的外侧上，并且特别地延伸到至少陶瓷轴5的长度。

7. 发明授权

US10592581B2 Method for inverse trajectory planning 有权
公开(公告)号：US10592581B2
公开(公告)日：2020-03-17
申请号：US14417929
申请日：2013-01-29
申请人： Brainlab AG
发明人： Rowena Thomson , Stephan Mittermeyer
IPC分类号： G06F17/10 , G06F19/00 , G16H50/50
摘要： The present invention relates to a data processing method of determining a trajectory of a medical instrument to be inserted into a patient's body for treatment of a target region in the patient's body, the method being executed by a computer and comprising the following steps: a) acquiring medical image data comprising medical image information describing an image of an anatomical body part; b) acquiring target region extent data comprising target region extent information describing a spatial extent of the target region in the medical image information; c) determining, based on the target region extent data, whether the spatial extent of the target region in the medical image information comprises more than one image particle; d) if it is determined that the target region comprises more than a predetermined number of image particles, determining, based on the medical image data, image particle weight data comprising image particle weight information describing a weight describing a tissue type component of the target region assigned to each target region image particle in the target region, which component is represented at least partly by the image particle, and determining, based on the image particle weight data and the medical image data, instrument trajectory data comprising instrument trajectory information describing a trajectory of the medical instrument along which the instrument is to be inserted into the patient's body.

8. 发明申请

US20180158547A1 Determination of Enhancing Structures in an Anatomical Body Part 审中-公开
公开(公告)号：US20180158547A1
公开(公告)日：2018-06-07
申请号：US15819995
申请日：2017-11-21
申请人： Brainlab AG
发明人： Rainer Lachner , Rowena Thomson , Christina von Freyberg
IPC分类号： G16H30/40 , G06T7/00 , G06T7/136 , G06T7/11 , G06T7/174 , G06T5/00 , G06T5/20 , G06T7/60 , G06T7/187
CPC分类号： G16H30/40 , G06T5/002 , G06T5/20 , G06T7/001 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T7/174 , G06T7/187 , G06T7/60 , G06T2207/10096 , G06T2207/20128 , G06T2207/20156 , G06T2207/20224 , G06T2207/30016 , G06T2207/30096
摘要： A data processing method for determining an enhancing structure of interest within an anatomical body part, wherein the structure of interest exhibits an enhanced signal in an image of the anatomical body part generated by a medical imaging method using a contrast agent, said method being designed to be performed by a computer and comprising a region growing algorithm.

9. 发明授权

US09849266B2 Agent delivery catheter 有权
公开(公告)号：US09849266B2
公开(公告)日：2017-12-26
申请号：US15120307
申请日：2014-02-20
申请人： Brainlab AG
发明人： Rowena Thomson , Martin Rube , Stephan Mittermeyer
IPC分类号： A61M5/32 , A61M25/00 , A61M25/01 , A61M25/04
CPC分类号： A61M25/008 , A61M25/002 , A61M25/0102 , A61M25/0108 , A61M25/0127 , A61M25/04 , A61M2025/0042 , A61M2205/0211 , A61M2210/0693
摘要： An agent delivery catheter including a first hollow tube and a second hollow tube that protrudes from a distal opening of the first hollow tube and defines an agent delivery lumen extending along the entire length of the catheter. The distal end of the first tube is coupled to the second tube to form an annular cavity between the first tube and the second tube, the annular cavity provided for accommodating a retractable stylet shaft. An adapting member is disposed on and coupled to a proximal end of a ceramic member and for receiving a distal end of the stylet shaft.

10. 发明申请

US20140228676A1 DETERMINATION OF A PHYSICALLY-VARYING ANATOMICAL STRUCTURE 有权
标题翻译：物理变化解剖结构的确定
公开(公告)号：US20140228676A1
公开(公告)日：2014-08-14
申请号：US14115997
申请日：2011-05-17
申请人： Brainlab AG
发明人： Rowena Thomson , Stephan Mittermeyer
IPC分类号： G06T7/00 , A61B5/06 , G06T5/50
CPC分类号： G06T7/0012 , A61B5/061 , G06T5/50 , G06T7/0016 , G06T7/215 , G06T7/97 , G06T2207/30016 , G06T2207/30096
摘要： The present invention relates to a data processing method for providing variation data which describe a physically-varying anatomical structure, in particular an indiscernible anatomical structure, in particular a non-enhancing tumour, comprising the steps of: providing second image data which describe a second image of a region of an anatomical body, wherein the region includes a second anatomical part which includes the physically-varying anatomical structure; providing first image data which represent a first image of the same region, wherein said same region includes a first anatomical part which does not include the physically-varying anatomical structure or which includes the physically-varying anatomical structure in a different physical state than in the second anatomical part; providing position change data which describe positional changes of corresponding image elements between the first image and the second image, on the basis of the first and second image data; and providing the variation data on the basis of the position change data.
摘要翻译：本发明涉及一种数据处理方法，用于提供描述物理变化的解剖结构，特别是不可辨认的解剖结构，特别是非增强肿瘤的变化数据，包括以下步骤：提供描述第二图像数据的第二图像数据解剖体的区域的图像，其中所述区域包括包括物理变化的解剖结构的第二解剖部分; 提供表示相同区域的第一图像的第一图像数据，其中所述相同区域包括不包括物理变化的解剖结构的第一解剖部分，或者包括物理上不同的物理状态的解剖结构，而不同于第二解剖部位; 提供基于第一和第二图像数据描述第一图像和第二图像之间的对应图像元素的位置变化的位置变化数据; 以及基于位置变化数据提供变化数据。

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