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1. 发明申请

US20110295111A1 SYSTEM FOR DETERMINING THE ORIENTATION OF A CATHETER 有权
标题翻译：用于确定导管的方向的系统
公开(公告)号：US20110295111A1
公开(公告)日：2011-12-01
申请号：US13148092
申请日：2010-02-04
申请人： Eberhard Sebastian Hansis , Michael Grass
发明人： Eberhard Sebastian Hansis , Michael Grass
IPC分类号： A61B5/05
CPC分类号： A61B19/54 , A61B90/39 , A61B2034/102 , A61B2090/376 , A61F2002/30619 , A61F2250/0097 , A61F2250/0098 , A61M25/0108
摘要： The present invention relates to a system for determining the orientation of a catheter (2). The system comprises a catheter (2), an asymmetric marker (11) attached to the catheter (2), and an imaging unit (25) for generating a projection image of the asymmetric marker (11), wherein the imaging unit (25) comprises a radiation source for generating radiation for projecting the asymmetric marker (11) in a projection plane and a detection unit for generating the projection image of the asymmetric marker (11) projected in the projection plane. The system comprises further an orientation determination unit for determining the orientation of the asymmetric marker (11) from the projection image of the asymmetric marker (11) and for determining the orientation of the catheter (2) from the determined orientation of the asymmetric marker (11). The asymmetric marker (11) is adapted such that the orientation of the asymmetric marker (11) is determinable from the projection image of the asymmetric marker (11) alone.
摘要翻译：本发明涉及一种用于确定导管（2）的取向的系统。该系统包括导管（2），附接到导管（2）的不对称标记（11）和用于产生不对称标记（11）的投影图像的成像单元（25），其中成像单元（25）包括用于产生用于在投影平面中投影非对称标记（11）的辐射的辐射源和用于产生投射在投影平面中的不对称标记（11）的投影图像的检测单元。该系统还包括一个取向确定单元，用于从不对称标记物（11）的投影图像中确定不对称标记物（11）的取向，并确定导管（2）从不对称标记物的确定取向 11）。不对称标记（11）适于使得非对称标记（11）的取向可以从单独的不对称标记（11）的投影图像确定。

2. 发明授权

US08983577B2 System for determining the orientation of a catheter 有权
标题翻译：用于确定导管取向的系统
公开(公告)号：US08983577B2
公开(公告)日：2015-03-17
申请号：US13148092
申请日：2010-02-04
申请人： Eberhard Sebastian Hansis , Michael Grass
发明人： Eberhard Sebastian Hansis , Michael Grass
IPC分类号： A61B5/00 , A61B19/00 , G03B42/02 , A61F2/30 , A61M25/01
CPC分类号： A61B19/54 , A61B90/39 , A61B2034/102 , A61B2090/376 , A61F2002/30619 , A61F2250/0097 , A61F2250/0098 , A61M25/0108
摘要： The present invention relates to a system for determining the orientation of a catheter (2). The system comprises a catheter (2), an asymmetric marker (11) attached to the catheter (2), and an imaging unit (25) for generating a projection image of the asymmetric marker (11), wherein the imaging unit (25) comprises a radiation source for generating radiation for projecting the asymmetric marker (11) in a projection plane and a detection unit for generating the projection image of the asymmetric marker (11) projected in the projection plane. The system comprises further an orientation determination unit for determining the orientation of the asymmetric marker (11) from the projection image of the asymmetric marker (11) and for determining the orientation of the catheter (2) from the determined orientation of the asymmetric marker (11). The asymmetric marker (11) is adapted such that the orientation of the asymmetric marker (11) is determinable from the projection image of the asymmetric marker (11) alone.
摘要翻译：本发明涉及一种用于确定导管（2）的取向的系统。该系统包括导管（2），附接到导管（2）的不对称标记（11）和用于产生不对称标记（11）的投影图像的成像单元（25），其中成像单元（25）包括用于产生用于在投影平面中投影非对称标记（11）的辐射的辐射源和用于产生投射在投影平面中的不对称标记（11）的投影图像的检测单元。该系统还包括一个取向确定单元，用于从不对称标记物（11）的投影图像中确定不对称标记物（11）的取向，并确定导管（2）从不对称标记物的确定取向 11）。不对称标记（11）适于使得非对称标记（11）的取向可以从单独的不对称标记（11）的投影图像确定。

3. 发明申请

US20120207373A1 THREE-DIMENSIONAL ANALYSIS OF LESIONS REPRESENTED BY IMAGE DATA 有权
标题翻译：图像数据表示的三维分析
公开(公告)号：US20120207373A1
公开(公告)日：2012-08-16
申请号：US13502475
申请日：2010-10-21
申请人： Michael Grass , Eberhard Sebastian Hansis , Thomas Buelow , Klaus Erhard
发明人： Michael Grass , Eberhard Sebastian Hansis , Thomas Buelow , Klaus Erhard
IPC分类号： G06K9/00
CPC分类号： A61B6/502 , A61B6/025 , A61B6/466 , G06K9/00208 , G06K9/6221 , G06T7/0012 , G06T2207/10072 , G06T2207/30068
摘要： A system for three-dimensional analysis of lesions in image data is disclosed. It comprises a lesion detection subsystem (1) for detecting individual lesions and three-dimensional positions of the individual lesions, based on e.g. breast image data (301). It comprises a cluster detection subsystem (2) for detecting a cluster of lesions (302), based on three-dimensional position information of lesions, and associating at least some of the individual lesions with the cluster of lesions (302), based on the three-dimensional positions of the individual lesions. The cluster detection subsystem (2) is arranged for detecting the cluster of lesions (302), based on the three-dimensional positions of the individual lesions. It comprises a cluster analysis subsystem (3) for analyzing the cluster of lesions (302).
摘要翻译：公开了一种用于图像数据中病变三维分析的系统。它包括病变检测子系统（1），用于根据例如病毒检测子系统（1）检测个体病变和个体病变的三维位置。乳房图像数据（301）。其包括用于基于损伤的三维位置信息来检测病变群集（302）的簇检测子系统（2），并且基于所述病变群集（302）将至少一些个体病变与所述病变簇（302）相关联个体病变的立体位置。群体检测子系统（2）被设置为基于个体病变的三维位置来检测病变簇（302）。它包括用于分析病变簇（302）的聚类分析子系统（3）。

4. 发明申请

US20120301003A1 RECONSTRUCTING AN OBJECT OF INTEREST 有权
标题翻译：重新建立利益对象
公开(公告)号：US20120301003A1
公开(公告)日：2012-11-29
申请号：US13515830
申请日：2010-12-10
申请人： Klaus Erhard , Michael Grass , Thomas Buelow , Eberhard Sebastian Hansis
发明人： Klaus Erhard , Michael Grass , Thomas Buelow , Eberhard Sebastian Hansis
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , G06T2211/436
摘要： A system for generating a reconstruction of an object of interest comprises a shape model generator (1) for generating a shape model representing a shape of the object in dependence on a plurality of projections of the object, and a reconstructor (2) for reconstructing the object, based on the projections, in dependence on the shape model to obtain the reconstruction of the object. The reconstructor (2) comprises a soft-tissue reconstructor (4) for generating a reconstruction favoring soft tissue, based on the plurality of projections, and a sparse reconstructor (5) for generating a reconstruction of sparse objects, based on the plurality of projections. The reconstructor (2) comprises a clipping subsystem (3) for clipping an outside of the object from the reconstruction, based on the shape model, or the reconstructor (2) is arranged for reconstructing only an inside and/or boundary of the object as defined by the shape model.
摘要翻译：用于生成感兴趣对象的重建的系统包括：形状模型生成器（1），用于根据对象的多个投影来生成表示对象的形状的形状模型;以及重建器（2），用于重建对象，根据投影，依靠形状模型获得物体的重建。重建器（2）包括用于基于多个投影产生有利于软组织的重建的软组织重建器（4），以及用于基于所述多个突起产生稀疏对象的重建的稀疏重建器（5）。重建器（2）包括用于基于形状模型从重构中剪除对象外部的剪辑子系统（3），或者重建器（2）被布置为仅重建对象的内部和/或边界，由形状模型定义。

5. 发明申请

US20120020462A1 VISUALIZATION OF THE CORONARY ARTERY TREE 有权
标题翻译：冠状动脉瘤的可视化
公开(公告)号：US20120020462A1
公开(公告)日：2012-01-26
申请号：US13131277
申请日：2009-11-20
申请人： Eberhard Sebastian Hansis , Michael Grass
发明人： Eberhard Sebastian Hansis , Michael Grass
IPC分类号： H05G1/10 , G06K9/60
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/541 , G06T11/006 , G06T2211/404
摘要： The present invention is related to a method for reconstruction of the coronary arteries and an examination apparatus for reconstruction of the coronary arteries. To provide improved coronary artery information, an apparatus and a method are provided where a gating signal is provided (32) and a first gated X-ray image sequence of one of the left or right branches of the coronary arteries is acquired (34) with injected contrast agent into the one of the left or right branches of the coronary arteries. Further, a second gated X-ray image sequence of the other branch of the coronary arteries is acquired (36) with injected contrast agent into said other branch. Then, a gated reconstructing (38) of the left and the right coronary artery is suggested and a volume data (40, 42) of the coronary arteries is generated. The volume data of the left and right coronary arteries is registered (44) in relation to time and space. Further; the registered volume data (48, 50) of the left and the right coronary arteries is combined and a combined coronary artery tree volume data set (52) is generated (54). Finally, the combined coronary tree volume data set is visualized (56).
摘要翻译：本发明涉及冠状动脉重建方法和冠状动脉重建检查装置。为了提供改善的冠状动脉信息，提供了一种装置和方法，其中提供门控信号（32），并且获取冠状动脉的左分支或右分支之一的第一选通X射线图像序列（34），其中将注射的造影剂注射到冠状动脉的左侧或右侧分支中。此外，冠状动脉的另一个分支的第二选通X射线图像序列（36）被注入造影剂获取到所述另一分支中。然后，建议左冠状动脉和右冠状动脉的门控重建（38），并且产生冠状动脉的体积数据（40,42）。左冠状动脉和右冠状动脉的体积数据相对于时间和空间被记录（44）。进一步; 组合左冠状动脉和右冠状动脉的记录体数据（48,50），并且生成组合的冠状动脉树体积数据组（52）（54）。最后，组合冠状动脉树体数据集可视化（56）。

6. 发明授权

US09087400B2 Reconstructing an object of interest 有权
标题翻译：重建感兴趣的对象
公开(公告)号：US09087400B2
公开(公告)日：2015-07-21
申请号：US13515830
申请日：2010-12-10
申请人： Klaus Erhard , Michael Grass , Thomas Buelow , Eberhard Sebastian Hansis
发明人： Klaus Erhard , Michael Grass , Thomas Buelow , Eberhard Sebastian Hansis
IPC分类号： G06K9/00 , G06T11/00
CPC分类号： G06T11/006 , G06T2211/436
摘要： A system for generating a reconstruction of an object of interest comprises a shape model generator (1) for generating a shape model representing a shape of the object in dependence on a plurality of projections of the object, and a reconstructor (2) for reconstructing the object, based on the projections, in dependence on the shape model to obtain the reconstruction of the object. The reconstructor (2) comprises a soft-tissue reconstructor (4) for generating a reconstruction favoring soft tissue, based on the plurality of projections, and a sparse reconstructor (5) for generating a reconstruction of sparse objects, based on the plurality of projections. The reconstructor (2) comprises a clipping subsystem (3) for clipping an outside of the object from the reconstruction, based on the shape model, or the reconstructor (2) is arranged for reconstructing only an inside and/or boundary of the object as defined by the shape model.
摘要翻译：用于生成感兴趣对象的重建的系统包括：形状模型生成器（1），用于根据对象的多个投影来生成表示对象的形状的形状模型;以及重建器（2），用于重建对象，根据投影，依靠形状模型获得物体的重建。重建器（2）包括一个软组织重构器（4），用于基于多个投影产生有利于软组织的重建，以及一个稀疏重建器（5），用于基于多个突起产生稀疏对象的重构。重建器（2）包括用于基于形状模型从重建中剪除对象外部的剪辑子系统（3），或者重建器（2）被布置为仅重构对象的内部和/或边界，由形状模型定义。

7. 发明授权

US08923474B2 Visualization of the coronary artery tree 有权
标题翻译：冠状动脉树的可视化
公开(公告)号：US08923474B2
公开(公告)日：2014-12-30
申请号：US13131277
申请日：2009-11-20
申请人： Eberhard Sebastian Hansis , Michael Grass
发明人： Eberhard Sebastian Hansis , Michael Grass
IPC分类号： G01N23/083 , A61B6/00 , G06T11/00
CPC分类号： A61B6/504 , A61B6/4441 , A61B6/466 , A61B6/481 , A61B6/541 , G06T11/006 , G06T2211/404
摘要： The present invention is related to a method for reconstruction of the coronary arteries and an examination apparatus for reconstruction of the coronary arteries. To provide improved coronary artery information, an apparatus and a method are provided where a gating signal is provided (32) and a first gated X-ray image sequence of one of the left or right branches of the coronary arteries is acquired (34) with injected contrast agent into the one of the left or right branches of the coronary arteries. Further, a second gated X-ray image sequence of the other branch of the coronary arteries is acquired (36) with injected contrast agent into said other branch. Then, a gated reconstructing (38) of the left and the right coronary artery is suggested and a volume data (40, 42) of the coronary arteries is generated. The volume data of the left and right coronary arteries is registered (44) in relation to time and space. Further; the registered volume data (48, 50) of the left and the right coronary arteries is combined and a combined coronary artery tree volume data set (52) is generated (54). Finally, the combined coronary tree volume data set is visualized (56).
摘要翻译：本发明涉及冠状动脉重建方法和冠状动脉重建检查装置。为了提供改善的冠状动脉信息，提供了一种装置和方法，其中提供门控信号（32），并且获取冠状动脉的左分支或右分支之一的第一选通X射线图像序列（34），其中将注射的造影剂注射到冠状动脉的左侧或右侧分支中。此外，冠状动脉的另一个分支的第二选通X射线图像序列（36）被注入造影剂获取到所述另一分支中。然后，建议左冠状动脉和右冠状动脉的门控重建（38），并且产生冠状动脉的体积数据（40,42）。左冠状动脉和右冠状动脉的体积数据相对于时间和空间被记录（44）。进一步; 组合左冠状动脉和右冠状动脉的记录体数据（48,50），并且生成组合的冠状动脉树体积数据组（52）（54）。最后，组合冠状动脉树体数据集可视化（56）。

8. 发明授权

US09089307B2 Three-dimensional analysis of lesions represented by image data 有权
标题翻译：由图像数据表示的病变的三维分析
公开(公告)号：US09089307B2
公开(公告)日：2015-07-28
申请号：US13502475
申请日：2010-10-21
申请人： Michael Grass , Eberhard Sebastian Hansis , Thomas Buelow , Klaus Erhard
发明人： Michael Grass , Eberhard Sebastian Hansis , Thomas Buelow , Klaus Erhard
IPC分类号： G06K9/00 , A61B6/00 , A61B6/02 , G06T7/00 , G06K9/62
CPC分类号： A61B6/502 , A61B6/025 , A61B6/466 , G06K9/00208 , G06K9/6221 , G06T7/0012 , G06T2207/10072 , G06T2207/30068
摘要： A system for three-dimensional analysis of lesions in image data is disclosed. It comprises a lesion detection subsystem (1) for detecting individual lesions and three-dimensional positions of the individual lesions, based on e.g. breast image data (301). It comprises a cluster detection subsystem (2) for detecting a cluster of lesions (302), based on three-dimensional position information of lesions, and associating at least some of the individual lesions with the cluster of lesions (302), based on the three-dimensional positions of the individual lesions. The cluster detection subsystem (2) is arranged for detecting the cluster of lesions (302), based on the three-dimensional positions of the individual lesions. It comprises a cluster analysis subsystem (3) for analyzing the cluster of lesions (302).
摘要翻译：公开了一种用于图像数据中病变三维分析的系统。它包括病变检测子系统（1），用于根据例如病毒检测子系统（1）检测个体病变和个体病变的三维位置。乳房图像数据（301）。其包括用于基于损伤的三维位置信息来检测病变群集（302）的簇检测子系统（2），并且基于所述病变群集（302）将至少一些个体病变与所述病变簇（302）相关联个体病变的立体位置。群体检测子系统（2）被设置为基于个体病变的三维位置来检测病变簇（302）。它包括用于分析病变簇（302）的聚类分析子系统（3）。

9. 发明授权

US09848843B2 Dynamic perfusion imaging 有权
公开(公告)号：US09848843B2
公开(公告)日：2017-12-26
申请号：US14112047
申请日：2012-04-17
申请人： Michael Grass , Holger Schmitt
发明人： Michael Grass , Holger Schmitt
IPC分类号： A61B6/00
CPC分类号： A61B6/481 , A61B6/00 , A61B6/486 , A61B6/503 , A61B6/507 , A61B6/5217 , A61B6/542 , A61B6/545 , F04C2270/0421
摘要： A method includes scanning a region of interest, during a contrast agent based perfusion scan, at a predetermined temporal sampling rate during contrast agent uptake in the region of interest, and generating time frame data indicative of the scanned region of interest. The method further includes identifying a predetermined change in an amount of the contrast agent in the region of interest from the time frame data. The method further includes scanning the region of interest at a lower temporal sampling rate, which is lower than the temporal sampling rate during the contrast agent uptake, in response to identifying the predetermined change in the amount of the contrast agent in the region of interest.

10. 发明授权

US09597042B2 Perfusion imaging 有权
公开(公告)号：US09597042B2
公开(公告)日：2017-03-21
申请号：US13266556
申请日：2010-04-09
申请人： Roland Proksa , Michael Grass
发明人： Roland Proksa , Michael Grass
IPC分类号： G06K9/00 , A61B6/03 , A61B6/00
CPC分类号： A61B6/032 , A61B6/481 , A61B6/482 , A61B6/486 , A61B6/504 , A61B6/507
摘要： A method is disclosed that includes decomposing, with a decomposer, agent-based time series projection data for an object or a subject into at least an agent based component. A projection data decomposer includes a time series decomposer that determines agent-based projection data based on agent-based time series projection data based on at least two energy dependent components. A computer readable storage medium containing instructions which, when executed by a computer, cause the computer to perform the act of determining an agent-based component of agent-based time series projection data utilizing at least two components of the agent-based time series projection is provided.

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