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1. 发明申请

US20120290110A1 Evaluating Composite Applications Through Graphical Modeling 审中-公开
标题翻译：通过图形建模评估复合应用
公开(公告)号：US20120290110A1
公开(公告)日：2012-11-15
申请号：US13107233
申请日：2011-05-13
申请人： Eitan Hadar , Donald F. Ferguson , Vincent R. Re , John P. Kane , Brian J. Hughes
发明人： Eitan Hadar , Donald F. Ferguson , Vincent R. Re , John P. Kane , Brian J. Hughes
IPC分类号： G06F19/00
CPC分类号： G06Q10/10
摘要： According to one embodiment of the present disclosure, a method for evaluating composite applications through graphical modeling may be provided. The method may include displaying one or more characteristic objects that are graphically associated with a first entity object. An indication of a score calculation methodology of the first entity object and an indication of a score calculation methodology of each characteristic object may be received. A score of each characteristic object may be determined. Each score may be based on at least one or more measurements of a measured object that is graphically associated with the first entity object and the score calculation methodology of the respective characteristic object. A score of the first entity object may be determined and displayed, the determination based on at least each score of the one or more characteristic objects and the score calculation methodology of the first entity object.
摘要翻译：根据本公开的一个实施例，可以提供通过图形建模来评估复合应用的方法。该方法可以包括显示与第一实体对象以图形方式相关联的一个或多个特征对象。可以接收第一实体对象的分数计算方法的指示和每个特征对象的得分计算方法的指示。可以确定每个特征对象的得分。每个分数可以基于与第一实体对象图形关联的测量对象和各个特征对象的分数计算方法的至少一个或多个测量。可以基于至少一个或多个特征对象的每个分数和第一实体对象的分数计算方法来确定和显示第一实体对象的分数。

2. 发明授权

US08578374B2 System and method for managing virtual machines 有权
标题翻译：用于管理虚拟机的系统和方法
公开(公告)号：US08578374B2
公开(公告)日：2013-11-05
申请号：US12504297
申请日：2009-07-16
申请人： John P. Kane
发明人： John P. Kane
IPC分类号： G06F9/455 , G06F9/46 , G06F7/04
CPC分类号： G06F9/45558 , G06F2009/45575 , G06F2009/45587
摘要： In some embodiments, a method for virtual machine management includes receiving a request for a first virtual machine from a virtual host. The method also includes comparing the request for the first virtual machine to a policy. The policy includes rules that govern access to a plurality of virtual machines. In addition, the method includes providing the virtual host access to a second virtual machine in response to comparing the request for the first virtual machine to the policy.
摘要翻译：在一些实施例中，用于虚拟机管理的方法包括从虚拟主机接收对第一虚拟机的请求。该方法还包括将第一虚拟机的请求与策略进行比较。该策略包括管理对多个虚拟机的访问的规则。此外，该方法包括提供对第二虚拟机的虚拟主机访问以响应于将第一虚拟机的请求与策略进行比较。

3. 发明授权

US08147608B2 Modified pigments and methods for making and using the same 有权
标题翻译：改性颜料及其制备和使用方法
公开(公告)号：US08147608B2
公开(公告)日：2012-04-03
申请号：US13042803
申请日：2011-03-08
申请人： Puthalath K. Sujeeth , Mark Ulrich , Gabe Srouji , John P. Kane , Daniel A. Ouellette
发明人： Puthalath K. Sujeeth , Mark Ulrich , Gabe Srouji , John P. Kane , Daniel A. Ouellette
IPC分类号： C09B67/00 , C09B67/10 , C09B67/14 , C09B67/16 , C09B67/20
CPC分类号： C09C1/56 , B82Y30/00 , C01P2002/70 , C01P2002/88 , C01P2004/03 , C01P2004/64 , C01P2006/12 , C01P2006/22 , C08K3/013 , C08K3/04 , C08K9/02 , C08K9/04 , C09C1/565 , C09D7/41 , C09D7/62 , C09D11/322
摘要： A method of producing a modified pigment by sulfonating a pigment and subsequently oxidizing the pigment. The modified pigment may have sulfonic acid and carboxyl surface modifying groups attached to the surface of the pigment. Charge balancing counterions such as alkali metals, alkaline earth metals and NR1R2R3H+, where R1, R2 and R3 are independently H or C1-C5 alkyl groups, may be associated with the surface modifying groups. The modified pigment is combined with water to produce a dispersion that can be used in such applications as coatings, paints, papers, adhesives, latexes, toners, textiles, fibers, plastics and inks.
摘要翻译：通过磺化颜料并随后氧化颜料来生产改性颜料的方法。改性颜料可以具有连接到颜料表面的磺酸和羧基表面改性基团。电荷平衡抗衡离子如碱金属，碱土金属和NR1R2R3H +，其中R1，R2和R3独立地为H或C1-C5烷基，可与表面改性基团相关联。将改性颜料与水结合以产生可用于涂料，涂料，纸，粘合剂，胶乳，调色剂，纺织品，纤维，塑料和油墨等分散体。

4. 发明申请

US20100251932A1 SELF-DISPERSING PARTICLES AND METHODS FOR MAKING AND USING THE SAME 有权
标题翻译：自分散颗粒及其制备和使用方法
公开(公告)号：US20100251932A1
公开(公告)日：2010-10-07
申请号：US12756175
申请日：2010-04-07
申请人： Puthalath K. Sujeeth , John P. Kane , Martial Blanc , Pascal Gruffel , Gilles Dolivo , Marco Ribezzo , Daniel A. Ouellette , Carol D. Landi , Rahul A. Ranade , Mark Ulrich
发明人： Puthalath K. Sujeeth , John P. Kane , Martial Blanc , Pascal Gruffel , Gilles Dolivo , Marco Ribezzo , Daniel A. Ouellette , Carol D. Landi , Rahul A. Ranade , Mark Ulrich
IPC分类号： C09D11/02 , C09D5/00 , C07F7/28 , C07D251/48 , C07D251/42 , C07F3/06 , C07F15/02
CPC分类号： C09D11/037 , A61K8/445 , A61K2800/412 , A61K2800/622 , A61Q1/02 , C01P2002/85 , C01P2004/62 , C01P2006/22 , C01P2006/62 , C01P2006/63 , C01P2006/64 , C07D251/54 , C09B67/0002 , C09B67/0009 , C09B67/0086 , C09C1/24 , C09C1/3684 , C09C3/12 , C09D7/41 , C09D11/326 , C09D11/328 , C09D15/00 , G02B5/223
摘要： A method of modifying a particle that includes reacting a reactive compound having an X—[Y]n reactive group with a secondary compound N—S-ZM to form a substituted reactive intermediate [Y]a—X—(N—S-ZM)b, and reacting the particle with the substituted reactive intermediate [Y]a—X—(N—S-ZM)b to attach the substituted reactive intermediate to the surface of the particle to form a surface modified particle. The particle may comprise at least one of a dye particle, an inorganic pigment particle, an additive, or a combination thereof. X may be a sulfonyl, phosphoryl, or 1,3,5-triazinyl group. Y may be a halogen leaving group. N may be a nucleophilic group. S may be an organic group. ZM may be an ionizable end group. Also, n is an integer between 1 and 3, b is an integer between 1 and 3, and a=n−b. When n is equal to or greater than b, and wherein if b is 2 or 3, each N—S-ZM can be the same or different.
摘要翻译：一种改性颗粒的方法，包括使具有X- [Y] n反应性基团的反应性化合物与次级化合物N-S-ZM反应以形成取代的反应性中间体[Y] a-X-（N-S-ZM ）b，并使该颗粒与取代的反应性中间体[Y] a-X-（N-S-ZM）b反应以将取代的反应性中间体连接到颗粒的表面以形成表面改性颗粒。颗粒可以包括染料颗粒，无机颜料颗粒，添加剂或其组合中的至少一种。 X可以是磺酰基，磷酰基或1,3,5-三嗪基。 Y可以是卤素离去基团。 N可以是亲核基团。 S可能是一个有机组。 ZM可以是可离子化的端基。此外，n是1和3之间的整数，b是1和3之间的整数，a = n-b。当n等于或大于b时，并且其中如果b是2或3，则每个N-S-ZM可以相同或不同。

5. 发明授权

US07470659B2 Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM) 失效
标题翻译：增加视网膜色素上皮（RPE）和Bruch's膜（BM）中逆转胆固醇转运的方法
公开(公告)号：US07470659B2
公开(公告)日：2008-12-30
申请号：US10794198
申请日：2004-03-05
申请人： Daniel M. Schwartz , Keith G. Duncan , Kathy R. Bailey , John P. Kane , Brian Y. Ishida
发明人： Daniel M. Schwartz , Keith G. Duncan , Kathy R. Bailey , John P. Kane , Brian Y. Ishida
IPC分类号： A61K38/02 , A61K38/17 , A61K31/685
CPC分类号： A61K31/685 , A61K31/66 , A61K38/17 , A61K38/1709 , A61K2300/00
摘要： The present invention addresses the treatment of age-related macular degeneration using regulation of pathogenic mechanisms similar to atherosclerosis. In further specific embodiments, compositions that increase reverse cholesterol transport are utilized as therapeutic targets for age-related macular degeneration. In a specific embodiment, the lipid content of the retinal pigment epithelium, and/or Bruch's membrane is reduced by delivering Apolipoprotein A1, particularly a mimetic peptide.
摘要翻译：本发明通过调节与动脉粥样硬化相似的致病机制来解决年龄相关性黄斑变性的治疗。在另外的具体实施方案中，增加反向胆固醇转运的组合物被用作年龄相关性黄斑变性的治疗靶标。在一个具体的实施方案中，通过递送载脂蛋白A1，特别是模拟肽来减少视网膜色素上皮和/或Bruch's膜的脂质含量。

6. 发明授权

US5072765A Auxiliary tire bead depressor 失效
标题翻译：辅助轮胎胎压抑制器
公开(公告)号：US5072765A
公开(公告)日：1991-12-17
申请号：US605547
申请日：1990-10-30
申请人： John P. Kane , Francis H. Goodman
发明人： John P. Kane , Francis H. Goodman
IPC分类号： B60C25/12 , B60C25/14
CPC分类号： B60C25/145
摘要： An auxiliary tire bead depressor is provided for use with an apparatus for inflating a tubeless tire having sidewalls and upper and lower annular tire beads. The tire is mounted on a wheel having upper and lower wheel flanges against which the upper and lower tire beads seal, respectively. The apparatus has an inflation head and an annular tire seal ring extending outwardly therefrom for depressing the tire sidewall. The auxiliary tire bead depressor comprises a mechanism, spaced from the annular tire seal ring, for selectively depressing the upper tire bead away from the upper wheel flange. The tire bead depressing mechanism is moved from an advanced position wherein the depressing mechanism engages and depresses the tire, to a retracted position wherein the depressing mechanism is spaced from the tire. The auxiliary tire bead depressor is mounted to the inflation head.
摘要翻译：提供了一种辅助轮胎胎压抑制器，用于充气具有侧壁和上下环形轮胎胎圈的无内胎轮胎的装置。轮胎安装在具有上和下轮缘的车轮上，上轮胎胎圈和下轮胎胎圈分别与胎圈密封。该装置具有从其向外延伸的膨胀头和环形轮胎密封环，用于压下轮胎侧壁。辅助轮胎胎压抑制器包括与环形轮胎密封环间隔开的机构，用于选择性地将上轮胎胎圈远离上轮胎凸缘压下。轮胎胎压按压机构从其中下压机构接合并压下轮胎的前进位置移动到缩回位置，其中按压机构与轮胎间隔开。辅助轮胎胎压抑制器安装到充气头。

7. 发明授权

US5023271A Pharmaceutical microemulsions 失效
标题翻译：药物微乳
公开(公告)号：US5023271A
公开(公告)日：1991-06-11
申请号：US765359
申请日：1985-08-13
申请人： Jean-Louis Vigne , John P. Kane
发明人： Jean-Louis Vigne , John P. Kane
IPC分类号： A61K9/107
CPC分类号： A61K9/1075
摘要： A method for parenteral administration of fat-soluble pharmaceuticals and vitamins using microemulsions is disclosed. The microemulsions are comprised of a naturally occurring amphipatic substance and a hydrophobic lipid along with the active ingredient, are size selected for 300-1000 .ANG. pseudomicelles, and permit safe intravenous injection of the active ingredient. Levels of the active ingredient in the various lipoprotein fractions of serum appear to mimic the natural distribution of the administered drug if taken orally.
摘要翻译：公开了一种使用微乳液肠胃外给药脂溶性药物和维生素的方法。微乳液由天然存在的两亲物质和疏水性脂质以及活性成分组成，其尺寸选择为300-1000个ANGSTROM假胶束，并允许安全地静脉内注射活性成分。血清各种脂蛋白级分中活性成分的含量似乎模拟了口服给药的药物的天然分布。

8. 发明授权

US4752657A Proximity switch mounting apparatus 失效
标题翻译：接近开关安装装置
公开(公告)号：US4752657A
公开(公告)日：1988-06-21
申请号：US46793
申请日：1987-05-07
申请人： John P. Kane , Billy Davenport , Ray Sidelinker
发明人： John P. Kane , Billy Davenport , Ray Sidelinker
IPC分类号： F15B15/28 , H01H1/58 , H01H3/60 , H01H9/02 , H01H36/00 , H01H35/38
CPC分类号： F15B15/2892 , H01H36/0033 , H01H1/58 , H01H3/60 , H01H36/0046 , H01H9/0207
摘要： A mounting apparatus for a proximity switch for sensing the position of a piston within a fluid operated, expandable chamber cylinder. The mounting device comprises a block shaped member with at least a first depressed, arcuate surface, the degree of curvature of which is adapted to fit the surface of the cylinder. By first attaching the mounting apparatus to the proximity switch and then positioning the proximity switch with respect to the fluid cylinder, tightening down of fastening devices provided for the proximity switch will cause the arcuate surface to firmly engage the surface of the cylinder, thereby providing a secure, vibration resistant mounting of the proximity switch to the cylinder.
摘要翻译：一种用于接近开关的安装装置，用于感测活塞在流体操作的可膨胀腔室气缸内的位置。安装装置包括具有至少第一凹陷的弓形表面的块状构件，其曲率适合于装配气缸的表面。通过首先将安装装置附接到接近开关，然后将接近开关相对于流体缸定位，为靠近开关设置的紧固装置的紧固将使得弓形表面牢固地接合气缸的表面，由此提供将接近开关固定，防震安装到气缸。

9. 发明授权

US10311171B2 Multi-component and mixed-reality simulation environments 有权
公开(公告)号：US10311171B2
公开(公告)日：2019-06-04
申请号：US14636134
申请日：2015-03-02
申请人： Steven L. Greenspan , Debra J. Danielson , James D. Reno , John P. Kane , Prashant Parikh
发明人： Steven L. Greenspan , Debra J. Danielson , James D. Reno , John P. Kane , Prashant Parikh
IPC分类号： H04W4/70 , G06F17/50
摘要： Systems and methods may include receiving real-time data about a real component operating in a real-world environment. The systems and methods may further include generating a virtual representation of the real component based on the real-time data about the real component and historical data associated with the real component. In addition, the systems and methods may include receiving injected data from a lab. The injected data may provide data about a lab component operating in the lab. The systems and methods may also include simulating, in a virtual environment, a real-time interaction in the real-world environment between the real component and the lab component using the virtual representation of the real component and the injected data. Moreover, the systems and methods may include determining a real-time performance characteristic of at least one of the lab component and the real component based on the simulated real-time interaction in the real-world environment.

10. 发明授权

US09221986B2 Self-dispersing particles and methods for making and using the same 有权
标题翻译：自分散颗粒及其制造和使用方法
公开(公告)号：US09221986B2
公开(公告)日：2015-12-29
申请号：US12756175
申请日：2010-04-07
申请人： Puthalath K. Sujeeth , John P. Kane , Daniel A. Ouellette , Mark Ulrich
发明人： Puthalath K. Sujeeth , John P. Kane , Daniel A. Ouellette , Mark Ulrich
IPC分类号： C09D11/00 , C09D11/037 , A61K8/44 , A61Q1/02 , C07D251/54 , C09B67/04 , C09B67/08 , C09B67/46 , C09C1/24 , C09C1/36 , C09C3/12 , C09D7/00 , C09D11/326 , C09D11/328 , C09D15/00 , G02B5/22
CPC分类号： C09D11/037 , A61K8/445 , A61K2800/412 , A61K2800/622 , A61Q1/02 , C01P2002/85 , C01P2004/62 , C01P2006/22 , C01P2006/62 , C01P2006/63 , C01P2006/64 , C07D251/54 , C09B67/0002 , C09B67/0009 , C09B67/0086 , C09C1/24 , C09C1/3684 , C09C3/12 , C09D7/41 , C09D11/326 , C09D11/328 , C09D15/00 , G02B5/223
摘要： A method of modifying a particle that includes reacting a reactive compound having an X—[Y]n reactive group with a secondary compound N—S-ZM to form a substituted reactive intermediate [Y]a—X—(N—S-ZM)b, and reacting the particle with the substituted reactive intermediate [Y]a—X—(N—S-ZM)b to attach the substituted reactive intermediate to the surface of the particle to form a surface modified particle. The particle may comprise at least one of a dye particle, an inorganic pigment particle, an additive, or a combination thereof. X may be a sulfonyl, phosphoryl, or 1,3,5-triazinyl group. Y may be a halogen leaving group. N may be a nucleophilic group. S may be an organic group. ZM may be an ionizable end group. Also, n is an integer between 1 and 3, b is an integer between 1 and 3, and a=n−b. When n is equal to or greater than b, and wherein if b is 2 or 3, each N—S-ZM can be the same or different.
摘要翻译：一种改性颗粒的方法，包括使具有X- [Y] n反应性基团的反应性化合物与次级化合物N-S-ZM反应以形成取代的反应性中间体[Y] a-X-（N-S-ZM ）b，并使该颗粒与取代的反应性中间体[Y] a-X-（N-S-ZM）b反应以将取代的反应性中间体连接到颗粒的表面以形成表面改性颗粒。颗粒可以包括染料颗粒，无机颜料颗粒，添加剂或其组合中的至少一种。 X可以是磺酰基，磷酰基或1,3,5-三嗪基。 Y可以是卤素离去基团。 N可以是亲核基团。 S可能是一个有机组。 ZM可以是可离子化的端基。此外，n是1和3之间的整数，b是1和3之间的整数，a = n-b。当n等于或大于b时，并且其中如果b是2或3，则每个N-S-ZM可以相同或不同。

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