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1. 发明授权

US08290247B2 Method and system for segmentation of tubular structures in 3D images 有权
标题翻译： 3D图像中管状结构分割的方法和系统
公开(公告)号：US08290247B2
公开(公告)日：2012-10-16
申请号：US12150817
申请日：2008-05-01
申请人： Gregory G. Slabaugh , Gozde Unal , Tong Fang , Brian Whited , Jaroslaw Rossignac
发明人： Gregory G. Slabaugh , Gozde Unal , Tong Fang , Brian Whited , Jaroslaw Rossignac
IPC分类号： G06K9/00
CPC分类号： G06K9/342 , G06T7/11 , G06T2200/04 , G06T2207/10072 , G06T2207/20101 , G06T2207/30101
摘要： A method and system for segmenting tubular structures in 3D images is disclosed. User inputs identifying a first region on the image inside of a tubular structure and a second region of the image outside of the tubular structure are received. Based on this information, an ordered series of pearls are generated along the tubular structure. Pearls are spheres, each having a center location and a radius determined based on the center locations and radii of previous pearls and on local voxel intensities in the image. A continuous model of the tubular structure can be generated by interpolating the center locations and radii of the ordered series of pearls. The ordered series of pearls can be displayed and easily edited in response to user input, thus providing an efficient and flexible method for interactive segmentation of a potion of interest in a tubular structure.
摘要翻译：公开了一种用于在3D图像中分割管状结构的方法和系统。接收识别管状结构内部的图像上的第一区域和管状结构外部的图像的第二区域的用户输入。基于该信息，沿着管状结构产生有序的珍珠系列。珍珠是球体，每个球体具有基于中心位置和先前珍珠的半径确定的中心位置和半径以及图像中的局部体素强度。可以通过内插有序系列珍珠的中心位置和半径来生成管状结构的连续模型。可以根据用户输入显示和容易地编辑有序的珍珠系列，从而为管状结构中感兴趣的药水进行交互式分割提供了一种有效和灵活的方法。

2. 发明申请

US20090016588A1 Method and system for segmentation of tubular structures in 3D images 有权
标题翻译： 3D图像中管状结构分割的方法和系统
公开(公告)号：US20090016588A1
公开(公告)日：2009-01-15
申请号：US12150817
申请日：2008-05-01
申请人： Gregory G. Slabaugh , Gozde Unal , Tong Fang , Brian Whited , Jaroslaw Rossignac
发明人： Gregory G. Slabaugh , Gozde Unal , Tong Fang , Brian Whited , Jaroslaw Rossignac
IPC分类号： G06K9/34
CPC分类号： G06K9/342 , G06T7/11 , G06T2200/04 , G06T2207/10072 , G06T2207/20101 , G06T2207/30101
摘要： A method and system for segmenting tubular structures in 3D images is disclosed. User inputs identifying a first region on the image inside of a tubular structure and a second region of the image outside of the tubular structure are received. Based on this information, an ordered series of pearls are generated along the tubular structure. Pearls are spheres, each having a center location and a radius determined based on the center locations and radii of previous pearls and on local voxel intensities in the image. A continuous model of the tubular structure can be generated by interpolating the center locations and radii of the ordered series of pearls. The ordered series of pearls can be displayed and easily edited in response to user input, thus providing an efficient and flexible method for interactive segmentation of a potion of interest in a tubular structure.
摘要翻译：公开了一种用于在3D图像中分割管状结构的方法和系统。接收识别管状结构内部的图像上的第一区域和管状结构外部的图像的第二区域的用户输入。基于该信息，沿管状结构产生有序的珍珠系列。珍珠是球体，每个球体具有基于中心位置和先前珍珠的半径确定的中心位置和半径以及图像中的局部体素强度。可以通过内插有序系列珍珠的中心位置和半径来生成管状结构的连续模型。可以根据用户输入显示和容易地编辑有序的珍珠系列，从而为管状结构中感兴趣的药水进行交互式分割提供了一种有效和灵活的方法。

3. 发明授权

US08218910B2 3D ball skinning using partial differential equations for generation of smooth tubular surfaces 有权
标题翻译：使用偏微分方程的3D球剥皮生成光滑的管状表面
公开(公告)号：US08218910B2
公开(公告)日：2012-07-10
申请号：US12413913
申请日：2009-03-30
申请人： Gregory G. Slabaugh , Jaroslaw Rossignac , Brian Whited , Tong Fang , Gozde Unal
发明人： Gregory G. Slabaugh , Jaroslaw Rossignac , Brian Whited , Tong Fang , Gozde Unal
IPC分类号： G06K9/32
CPC分类号： G06T17/10
摘要： A method of computing a continuous interpolation of a discrete set of three-dimensional (3D) balls, including generating an initial skin, wherein the initial skin is a surface comprised of splines and wherein the splines touch each ball along a circle that is tangent to the ball, solving a first differential equation to minimize the initial skin's surface area or solving a second differential equation to minimize a squared mean curvature of the initial skin's surface, wherein the result of solving the first or second differential equations is an updated skin; and repeating the steps of solving the first or second differential equations for the updated skin, and then, repeating the steps of solving the first or second differential equations for each subsequently updated skin until a desired skin is realized.
摘要翻译：一种计算三维（3D）球的离散组的连续插值的方法，包括生成初始皮肤，其中所述初始皮肤是由样条线组成的表面，并且其中所述花键沿着与所述三维球，解决第一微分方程以最小化初始皮肤的表面积或求解第二微分方程以最小化初始皮肤表面的平均平均曲率，其中求解第一或第二微分方程的结果是更新的皮肤; 并且重复解决用于更新的皮肤的第一或第二微分方程的步骤，然后重复以下步骤：为每个随后更新的皮肤求解第一或第二微分方程，直到实现期望的皮肤。

4. 发明申请

US20100045671A1 3D BALL SKINNING USING PARTIAL DIFFERENTIAL EQUATIONS FOR GENERATION OF SMOOTH TUBULAR SURFACES 有权
标题翻译：使用部分微分方程式生成平滑管状表面的3D球状皮肤
公开(公告)号：US20100045671A1
公开(公告)日：2010-02-25
申请号：US12413913
申请日：2009-03-30
申请人： Gregory G. Slabaugh , Jaroslaw Rossignac , Brian Whited , Tong Fang , Gozde Unal
发明人： Gregory G. Slabaugh , Jaroslaw Rossignac , Brian Whited , Tong Fang , Gozde Unal
IPC分类号： G06T17/00
CPC分类号： G06T17/10
摘要： A method of computing a continuous interpolation of a discrete set of three-dimensional (3D) balls, including generating an initial skin, wherein the initial skin is a surface comprised of splines and wherein the splines touch each ball along a circle that is tangent to the ball, solving a first differential equation to minimize the initial skin's surface area or solving a second differential equation to minimize a squared mean curvature of the initial skin's surface, wherein the result of solving the first or second differential equations is an updated skin; and repeating the steps of solving the first or second differential equations for the updated skin, and then, repeating the steps of solving the first or second differential equations for each subsequently updated skin until a desired skin is realized.
摘要翻译：一种计算三维（3D）球的离散组的连续插值的方法，包括生成初始皮肤，其中所述初始皮肤是由样条线组成的表面，并且其中所述花键沿着与所述三维所述球解决第一微分方程以最小化初始皮肤的表面积或求解第二微分方程以最小化初始皮肤表面的平均平均曲率，其中求解第一或第二微分方程的结果是更新的皮肤; 并且重复解决用于更新的皮肤的第一或第二微分方程的步骤，然后重复以下步骤：为每个随后更新的皮肤求解第一或第二微分方程，直到实现期望的皮肤。

5. 发明授权

US08280125B2 Method and system for segmentation of tubular structures using pearl strings 有权
标题翻译：使用珍珠串分割管状结构的方法和系统
公开(公告)号：US08280125B2
公开(公告)日：2012-10-02
申请号：US12012385
申请日：2008-02-01
申请人： Gregory G. Slabaugh , Gozde Unal , Tong Fang , Brian Whited , Jarek Rossignac
发明人： Gregory G. Slabaugh , Gozde Unal , Tong Fang , Brian Whited , Jarek Rossignac
IPC分类号： G06K9/00
CPC分类号： G06T7/149 , G06T7/11 , G06T2207/30101
摘要： A method and system for segmenting tubular or stroke-like structures in 2D images is disclosed. Examples of such structures include, but are not limited to, blood vessels, bones, roads, rivers, electrical wirings, and brush-strokes. User inputs identifying a first region on the image inside of a tubular structure and a second region of the image outside of the tubular structure are received. Based on this information, an ordered series of pearls are generated along the tubular structure. Pearls are 2D disks, each having a center location and a radius determined based on local pixel intensities in the image. A continuous model of the tubular structure is generated by interpolating the center locations and radii of the ordered series of pearls.
摘要翻译：公开了一种用于在2D图像中分割管状或笔触状结构的方法和系统。这种结构的实例包括但不限于血管，骨骼，道路，河流，电气布线和笔触。接收识别管状结构内部的图像上的第一区域和管状结构外部的图像的第二区域的用户输入。基于该信息，沿管状结构产生有序的珍珠系列。珍珠是2D盘，每个盘具有基于图像中的局部像素强度确定的中心位置和半径。通过内插有序系列珍珠的中心位置和半径来产生管状结构的连续模型。

6. 发明申请

US20080187197A1 Method and system for segmentation of tubular structures using pearl strings 有权
标题翻译：使用珍珠串分割管状结构的方法和系统
公开(公告)号：US20080187197A1
公开(公告)日：2008-08-07
申请号：US12012385
申请日：2008-02-01
申请人： Gregory G. Slabaugh , Gozde Unal , Tong Fang , Brian Whited , Jarek Rossignnac
发明人： Gregory G. Slabaugh , Gozde Unal , Tong Fang , Brian Whited , Jarek Rossignnac
IPC分类号： G06K9/00
CPC分类号： G06T7/149 , G06T7/11 , G06T2207/30101
摘要： A method and system for segmenting tubular or stroke-like structures in 2D images is disclosed. Examples of such structures include, but are not limited to, blood vessels, bones, roads, rivers, electrical wirings, and brush-strokes. User inputs identifying a first region on the image inside of a tubular structure and a second region of the image outside of the tubular structure are received. Based on this information, an ordered series of pearls are generated along the tubular structure. Pearls are 2D disks, each having a center location and a radius determined based on local pixel intensities in the image. A continuous model of the tubular structure is generated by interpolating the center locations and radii of the ordered series of pearls.
摘要翻译：公开了一种用于在2D图像中分割管状或笔触状结构的方法和系统。这种结构的实例包括但不限于血管，骨骼，道路，河流，电气布线和笔触。接收用于识别管状结构内的图像上的第一区域和管状结构外部的图像的第二区域的用户输入。基于该信息，沿管状结构产生有序的珍珠系列。珍珠是2D盘，每个盘具有基于图像中的局部像素强度确定的中心位置和半径。通过内插有序系列珍珠的中心位置和半径来产生管状结构的连续模型。

7. 发明授权

US07957591B2 Method and apparatus for performing segmentation based on partial differential equations 有权
标题翻译：基于偏微分方程进行分割的方法和装置
公开(公告)号：US07957591B2
公开(公告)日：2011-06-07
申请号：US11538849
申请日：2006-10-05
申请人： Gozde Unal , Bertrand Peny , Gregory G. Slabaugh , Christopher Alvino , Tong Fang
发明人： Gozde Unal , Bertrand Peny , Gregory G. Slabaugh , Christopher Alvino , Tong Fang
IPC分类号： G06K9/34
CPC分类号： G06T7/11 , G06T2207/10072 , G06T2207/20104 , G06T2207/20156 , G06T2207/30096
摘要： Disclosed is a method and system for propagating information about an image to segment a target structure. An input to denote a region of interest of the image containing the target structure is received. A first seed is set outside of the target structure and a second seed is set inside the target structure. A first partial differential equation (PDE) associated with the first seed is solved and a second PDE associated with the second seed is solved to segment the image.
摘要翻译：公开了一种用于传播关于图像的信息以分割目标结构的方法和系统。接收用于表示包含目标结构的图像的感兴趣区域的输入。将第一种子设置在目标结构之外，并且将第二种子设置在目标结构内。解决与第一种子相关联的第一偏微分方程（PDE），并且解决与第二种子相关联的第二PDE以分割图像。

8. 发明授权

US07831078B2 System and method for statistical shape model based segmentation of intravascular ultrasound and optical coherence tomography images 有权
标题翻译：用于基于统计形态模型的血管内超声和光学相干断层扫描图像分割的系统和方法
公开(公告)号：US07831078B2
公开(公告)日：2010-11-09
申请号：US11779413
申请日：2007-07-18
申请人： Gozde Unal , Susann Bucher , Gregory G. Slabaugh , Tong Fang
发明人： Gozde Unal , Susann Bucher , Gregory G. Slabaugh , Tong Fang
IPC分类号： G06K9/00
CPC分类号： G06K9/621 , G06K2209/05 , G06T7/12 , G06T7/149 , G06T7/174 , G06T2207/10081 , G06T2207/10132 , G06T2207/30101 , Y10S128/922
摘要： A method for segmenting intravascular images includes acquiring a series of digitized images acquired from inside a vessel, each said image comprising a plurality of intensities corresponding to a 2-dimensional grid of pixels, providing a precomputed set of shapes for modeling contours of vessel wall boundaries, wherein a contour can be expressed as a sum of a mean shape and a inner product of shape modes and shape weights, initializing a boundary contour for one of said set of images, initializing said shape weights by projecting a contour into said shape modes, updating said shape weights from differential equations of said shape weights, and computing a contour by summing said mean shape and said inner product of shape modes and updated shape weights.
摘要翻译：用于分割血管内图像的方法包括获取从血管内获取的一系列数字化图像，每个所述图像包括对应于像素的二维网格的多个强度，提供用于建模血管壁边界的轮廓的预先计算的一组形状其中轮廓可以表示为平均形状和形状模式和形状权重的内积的和，初始化所述图像集合中的一个图像的边界轮廓，通过将轮廓投影到所述形状模式中来初始化所述形状权重，从所述形状权重的微分方程更新所述形状权重，以及通过将所述平均形状和形状模式的内积与更新的形状权重相加来计算轮廓。

9. 发明申请

US20080260221A1 System and Method for Lesion Segmentation in Whole Body Magnetic Resonance Images 有权
标题翻译：全身磁共振图像中病变分割的系统和方法
公开(公告)号：US20080260221A1
公开(公告)日：2008-10-23
申请号：US12045327
申请日：2008-03-10
申请人： Gozde Unal , Gregory G. Slabaugh , Tong Fang , Shawn Linkton , Valer Canda , Stefan Thesen , Shuping Qing
发明人： Gozde Unal , Gregory G. Slabaugh , Tong Fang , Shawn Linkton , Valer Canda , Stefan Thesen , Shuping Qing
IPC分类号： G06K9/00
CPC分类号： G06K9/6207 , G06F19/00 , G06K9/342 , G06K2009/366 , G06K2209/053 , G06T7/12 , G06T7/149 , G06T7/194 , G06T2200/04 , G06T2207/10088 , G06T2207/20104 , G06T2207/30096
摘要： A method for lesion segmentation in 3-dimensional (3D) digital images, includes selecting a 2D region of interest (ROI) from a 3D image, the ROI containing a suspected lesion, extending borders of the ROI to 3D forming a volume of interest (VOI), where voxels on the borders of the VOI are initialized as background voxels and voxels in an interior of the VOI are initialized as foreground voxels, propagating a foreground and background voxel competition where for each voxel in the VOI, having each neighbor voxel in a neighborhood of the voxel attack the voxel, and, if the attack is successful, updating a label and strength of the voxel with that of the successful attacking voxel, and evolving a surface between the foreground and background voxels in 3D until an energy functional associated with the surface converges in value, where the surface segments the suspected lesion from the image.
摘要翻译：一种用于三维（3D）数字图像中的病变分割的方法，包括从3D图像中选择感兴趣的2D区域（ROI），ROI包含疑似病变，将ROI的边界延伸到形成感兴趣体积的3D（ VOI），其中VOI边界上的体元被初始化为背景体元素，并且VOI内部的体素被初始化为前景体素，传播前景和背景体素竞争，其中对于VOI中的每个体素，具有每个相邻体素体素的邻域攻击体素，并且如果攻击成功，更新体素的标签和强度与成功的攻击体素的标记和强度，并且以3D形式在前景和背景体素之间演变出一个表面，直到能量功能相关其表面收敛于值，其中表面将图像中的可疑病变分割。

10. 发明授权

US08069022B2 Method and apparatus for the classification of surface features of an ear impression 有权
标题翻译：用于分类耳朵表面特征的方法和装置
公开(公告)号：US08069022B2
公开(公告)日：2011-11-29
申请号：US11465628
申请日：2006-08-18
申请人： Gregory G. Slabaugh , Gozde Unal , Tong Fang
发明人： Gregory G. Slabaugh , Gozde Unal , Tong Fang
IPC分类号： G06G17/50 , G06G7/48 , H04R25/00
CPC分类号： G06K9/6206 , H04R25/652 , H04R25/658 , H04R2225/77
摘要： A method and apparatus is disclosed whereby a point on an ear impression model to be labeled is selected and a shape context is determined for that point. This shape context is then compared to average shape contexts for different regions on a reference ear impression model, also referred to herein as an ear impression shape atlas. A cost function is used to determine the minimum cost between the shape context for the selected point and one of the average shape contexts. Once the minimized cost is determined, the region label corresponding to the average shape context having a minimized cost is assigned to that point. In this way, points on the surface of an ear impression are classified and labeled as being located in regions corresponding to the regions on the ear impression shape atlas.
摘要翻译：公开了一种方法和装置，由此选择要标记的耳朵印象模型上的点，并且为该点确定形状上下文。然后将该形状上下文与参考耳部印象模型上的不同区域的平均形状上下文进行比较，这里也称为耳朵印象形状图集。成本函数用于确定所选点的形状上下文与平均形状上下文之间的最小成本。一旦确定了最小化成本，则将具有最小化成本的平均形状上下文对应的区域标签分配给该点。以这种方式，将耳朵表面的点分类并标记为位于与耳朵印象形状图集上的区域对应的区域中。

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