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    • 1. 发明申请
    • THROMBUS REMOVAL SYSTEM AND PROCESS
    • THROMBUS移除系统和过程
    • US20110230909A1
    • 2011-09-22
    • US13152004
    • 2011-06-02
    • John KucharczykStephanos Finitsis
    • John KucharczykStephanos Finitsis
    • A61F2/01
    • A61F2/01A61B17/12022A61B17/12145A61B17/1215A61B17/1219A61B17/221A61B17/32056A61B2017/22034A61B2017/2212A61F2002/016A61F2230/0078A61F2230/0091
    • A device capable of capturing and facilitating the removal of a thrombus in blood vessels (or stones in biliary or urinary ducts, or foreign bodies) uses a soft coil mesh with the aid of a pull wire or string to engage the surface of a thrombus, and remove the captured thrombus. The soft coil mesh is formed by an elongated microcoil element that forms the helical elements of a macrocoil element. The microcoil element provides a relatively elastic effect to the helical elements forming the macrocoil and allows for control of gripping forces on the thrombus while reducing non-rigid contact of the device with arterial walls. The use of multiple coil mesh elements, delivered through a single lumen or multiple lumens, preferably with separate control of at least one end of each coil, provides a firm grasp on a distal side of a thrombus, assisting in non-disruptive or minimally disrupted removal of the thrombus upon withdrawal of the device.
    • 能够捕获和促进血管(或胆管或泌尿道或异物中的石块)的去除的装置使用软线圈网,借助于拉丝或绳子来接合血栓的表面, 并取出捕获的血栓。 软线圈网由形成大量线圈元件的螺旋元件的细长的微线圈元件形成。 微线圈元件对形成大螺线管的螺旋元件提供相对弹性的效果,并且允许控制血栓上的夹持力,同时减少装置与动脉壁的非刚性接触。 使用通过单个腔或多个流明递送的多个线圈网状元件,优选地具有每个线圈的至少一个端部的单独控制,在血栓的远端侧提供牢固的抓握,辅助非破坏性或最小程度的破坏 取出装置时取出血栓。
    • 2. 发明授权
    • Thrombus removal system and process
    • 血栓清除系统和过程
    • US07955345B2
    • 2011-06-07
    • US11356321
    • 2006-02-16
    • John KucharczykStephanos Finitsis
    • John KucharczykStephanos Finitsis
    • A61B17/22
    • A61F2/01A61B17/12022A61B17/12145A61B17/1215A61B17/1219A61B17/221A61B17/32056A61B2017/22034A61B2017/2212A61F2002/016A61F2230/0078A61F2230/0091
    • A device capable of capturing and facilitating the removal of a thrombus in blood vessels (or stones in biliary or urinary ducts, or foreign bodies) uses a soft coil mesh with the aid of a pull wire or string to engage the surface of a thrombus, and remove the captured thrombus. The soft coil mesh is formed by an elongated microcoil element that forms the helical elements of a macrocoil element. The microcoil element provides a relatively elastic effect to the helical elements forming the macrocoil and allows for control of gripping forces on the thrombus while reducing non-rigid contact of the device with arterial walls. The use of multiple coil mesh elements, delivered through a single lumen or multiple lumens, preferably with separate control of at least one end of each coil, provides a firm grasp on a distal side of a thrombus, assisting in non-disruptive or minimally disrupted removal of the thrombus upon withdrawal of the device.
    • 能够捕获和促进血管(或胆管或泌尿道或异物中的石块)的去除的装置使用软线圈网,借助于拉丝或绳子来接合血栓的表面, 并取出捕获的血栓。 软线圈网由形成大量线圈元件的螺旋元件的细长的微线圈元件形成。 微线圈元件对形成大螺线管的螺旋元件提供相对弹性的效果,并且允许控制血栓上的夹持力,同时减少装置与动脉壁的非刚性接触。 使用通过单个腔或多个流明递送的多个线圈网状元件,优选地具有每个线圈的至少一个端部的单独控制,在血栓的远端侧提供牢固的抓握,辅助非破坏性或最小程度的破坏 取出装置时取出血栓。
    • 4. 发明授权
    • Thrombus removal system and process
    • 血栓清除系统和过程
    • US08603122B2
    • 2013-12-10
    • US11974490
    • 2007-10-12
    • James L. PokorneyStephanos FinitsisJohn Kucharczyk
    • James L. PokorneyStephanos FinitsisJohn Kucharczyk
    • A61B17/22
    • A61B17/221A61B2017/22034
    • A device capable of capturing and facilitating the removal of a thrombus in blood vessels (or stones in biliary or urinary ducts, or foreign bodies) uses a soft coil mesh with the aid of a pull wire or string to engage the surface of a thrombus, and remove the captured thrombus. The soft coil mesh is formed by an elongated microcoil element that forms the helical elements of a macrocoil element. The microcoil element provides a relatively elastic effect to the helical elements forming the macrocoil and allows for control of gripping forces on the thrombus while reducing non-rigid contact of the device with arterial walls. The use of multiple coil mesh elements, delivered through a single lumen or multiple lumens, preferably with separate control of at least one end of each coil, provides a firm grasp on a distal side of a thrombus, assisting in non-disruptive or minimally disrupted removal of the thrombus upon withdrawal of the device.
    • 能够捕获和促进血管(或胆管或泌尿道或异物中的石块)的去除的装置使用软线圈网,借助于拉丝或绳子来接合血栓的表面, 并取出捕获的血栓。 软线圈网由形成大量线圈元件的螺旋元件的细长的微线圈元件形成。 微线圈元件对形成大螺线管的螺旋元件提供相对弹性的效果,并且允许控制血栓上的夹持力,同时减少装置与动脉壁的非刚性接触。 使用通过单个腔或多个流明递送的多个线圈网状元件,优选地具有每个线圈的至少一个端部的单独控制,在血栓的远端侧提供牢固的抓握,辅助非破坏性或最小程度的破坏 取出装置时取出血栓。
    • 5. 发明申请
    • Thrombus removal system and process
    • 血栓清除系统和过程
    • US20080091223A1
    • 2008-04-17
    • US11974490
    • 2007-10-12
    • James PokorneyStephanos FinitsisJohn Kucharczyk
    • James PokorneyStephanos FinitsisJohn Kucharczyk
    • A61B17/22
    • A61B17/221A61B2017/22034
    • A device capable of capturing and facilitating the removal of a thrombus in blood vessels (or stones in biliary or urinary ducts, or foreign bodies) uses a soft coil mesh with the aid of a pull wire or string to engage the surface of a thrombus, and remove the captured thrombus. The soft coil mesh is formed by an elongated microcoil element that forms the helical elements of a macrocoil element. The microcoil element provides a relatively elastic effect to the helical elements forming the macrocoil and allows for control of gripping forces on the thrombus while reducing non-rigid contact of the device with arterial walls. The use of multiple coil mesh elements, delivered through a single lumen or multiple lumens, preferably with separate control of at least one end of each coil, provides a firm grasp on a distal side of a thrombus, assisting in non-disruptive or minimally disrupted removal of the thrombus upon withdrawal of the device.
    • 能够捕获和促进血管(或胆管或泌尿道或异物中的石块)的去除的装置使用软线圈网,借助于拉丝或绳子来接合血栓的表面, 并取出捕获的血栓。 软线圈网由形成大量线圈元件的螺旋元件的细长的微线圈元件形成。 微线圈元件对形成大螺线管的螺旋元件提供相对弹性的效果,并且允许控制血栓上的夹持力,同时减少装置与动脉壁的非刚性接触。 使用通过单个腔或多个流明递送的多个线圈网状元件,优选地具有每个线圈的至少一个端部的单独控制,在血栓的远端侧提供牢固的抓握,辅助非破坏性或最小程度的破坏 取出装置时取出血栓。
    • 10. 发明授权
    • Device and method for the endovascular treatment of aneurysms
    • 动脉瘤血管内治疗的装置和方法
    • US06463317B1
    • 2002-10-08
    • US09081319
    • 1998-05-19
    • John KucharczykRichard Latchaw
    • John KucharczykRichard Latchaw
    • A61B5055
    • A61F2/958A61B5/02014A61B5/055A61B5/411A61B5/4839A61B17/12022A61B17/12113A61B17/12136A61B17/1214A61B17/1219A61B2090/374
    • This invention provides a method and a device for treating hemodynamically significant aneurysms especially in the intracranial and extracranial circulation regions using either X-ray fluoroscopy or real-time magnetic resonance (MR) imaging guidance. An MR-visible parachute-shaped occlusion device, e.g., containing multiple elongated filamentary loops made of a memory metal, elastomeric hydrogel or other expansile material, is deployed into the aneurysm by radial expansion of the expansile material outwardly into contact with the interior aneurysm surface. The device is firmly positioned against the interior aneurysm surface using a coating which adheres to that interior aneurysm surface. The device may be filled with a hardenable polymer for permanent and complete aneurysm occlusion. Wide-neck aneurysms may be treated with the same device, with the addition of a temporary balloon expanded in the parent vessel to allow expansion of the occluding device within the aneurysm, instillation of the polymer into the device, and detachment of the device from the transporting catheter. Detachment of the aneurysm occlusion device from a transport catheter is achieved by mechanical, electrical and/or chemical decoupling. A coating applied to the surface of the parachute device may induce thrombotic occlusion of the aneurysm by timed delivery of biologic modifier drugs which promote collagen formation, fibroblast growth, and endothelial ingrowth within the aneurysm. The catheter systems may have attached microcoils or may be impregnated with MR-visible agents to permit visualization in MR imaging systems.
    • 本发明提供一种用于使用X射线荧光透视或实时磁共振(MR)成像指导,特别是在颅内和颅外循环区域中治疗血液动力学显着的动脉瘤的方法和装置。 MR记录的降落伞形闭塞装置,例如包含由记忆金属,弹性体水凝胶或其它可膨胀材料制成的多个细长丝状环,通过向外膨胀膨胀材料径向膨胀而与内部动脉瘤表面接触而部署到动脉瘤中 。 该装置使用粘附于内部动脉瘤表面的涂层牢固地抵靠内部动脉瘤表面定位。 该装置可以填充用于永久和完全动脉瘤闭塞的可硬化聚合物。 可以使用相同的装置处理宽颈动脉瘤,同时在母体血管中添加临时囊扩张,以允许阻塞装置在动脉瘤内膨胀,将聚合物滴入装置中,并将装置从 运输导管。 通过机械,电和/或化学去耦实现动脉瘤闭塞装置从运输导管的分离。 施加到降落伞装置的表面上的涂层可以通过定时递送促进胶原形成,成纤维细胞生长和动脉内皮内向内生长的生物修饰剂药物来引起动脉瘤的血栓闭塞。 导管系统可以具有附接的微线圈或可以用MR-可见剂浸渍以允许MR成像系统中的可视化。