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    • 4. 发明申请
    • OPHTHALMIC DEVICES COMPRISING PHOTOCHROMIC MATERIALS WITH REACTIVE SUBSTITUENTS
    • 含有反应性替代物的光致变色材料的光学器件
    • US20150241601A1
    • 2015-08-27
    • US14705175
    • 2015-05-06
    • Johnson & Johnson Vision Care, Inc.
    • Wenjing XiaoBarry Van GemertShivkumar MahadevanFrank Molock
    • G02B1/04G02C7/04
    • G02B1/041G02B1/043G02B5/23G02C7/04G03C1/73Y10T428/31935
    • Various non-limiting embodiments of the present disclosure relate to ophthalmic devices comprising photochromic materials comprising a reactive substituent. For example, the present disclosure contemplates ophthalmic devices comprising photochromic materials, such as photochromic naphthopyrans and indeno-fused naphthopyrans having a reactive substituent comprising a reactive moiety linked to the photochromic naphthopyran by one or more linking groups. In certain non-limiting embodiments, the reactive moiety comprises a polymerizable moiety. In other non-limiting embodiments, the reactive moiety comprises a nucleophilic moiety. Other non-limiting embodiments of the present disclosure relate to methods of making the photochromic ophthalmic device, wherein the photochromic ophthalmic devices comprise the photochromic naphthopyrans described herein.
    • 本公开的各种非限制性实施方案涉及包含含有反应性取代基的光致变色材料的眼科装置。 例如,本公开涉及包含光致变色材料的光学装置,例如具有包含通过一个或多个连接基团与光致变色萘并吡喃连接的反应性部分的反应性取代基的光致变色萘并吡喃和茚并稠合萘并吡喃。 在某些非限制性实施方案中,反应性部分包含可聚合部分。 在其它非限制性实施方案中,反应性部分包含亲核部分。 本公开的其它非限制性实施方案涉及制备光致变色眼科装置的方法,其中光致变色眼科装置包含本文所述的光致变色萘并吡喃。