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1. 发明申请

US20140369582A1 Method of Determining the Probabilities of Suspect Nodules Being Malignant 审中-公开
标题翻译：确定可疑结节恶性概率的方法
公开(公告)号：US20140369582A1
公开(公告)日：2014-12-18
申请号：US13918981
申请日：2013-06-16
申请人： Larry D. PARTAIN
发明人： Larry D. PARTAIN
IPC分类号： G06T7/00
CPC分类号： G06T7/0014 , G06T2207/10081 , G06T2207/20076 , G06T2207/30064
摘要： Methods of determining a probability of a suspect cancer nodule being malignant are provided. In one embodiment, the method begins with tabulating histogram data of malignant and benign nodules as a function of biomarker values for a specified patient population suspect of having a specific type of cancer. Next, the tabulated histogram data is separated into a plurality of biomarker bins where the bins are ranges of biomarker values, and malignancy probability fractions are calculated for each biomarker bin by dividing a number of true positives in each marker bin by a summed total of all true and false positives in each bin. Finally, a suspect nodule in a patient is scanned, a biomarker value for the suspect nodule determined, and a malignancy probability for the suspect nodule determined by reference to the tabulated histogram data and the malignancy probability fractions. Other embodiments are also disclosed.
摘要翻译：提供了确定可疑癌症结节恶性概率的方法。在一个实施方案中，该方法开始列出恶性和良性结节的直方图数据，作为具有特定类型癌症的特定患者群体的生物标志物值的函数。接下来，列表的直方图数据被分成多个生物标志物箱，其中箱是生物标记值的范围，并且通过将每个标记箱中的真阳性数除以总和的总数，计算每个生物标记箱的恶性概率分数每个垃圾箱中的真假。最后，扫描患者中的疑似结节，确定疑似结节的生物标记值，并通过参考列表直方图数据和恶性概率分数确定疑似结节的恶性概率。还公开了其他实施例。

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