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    • 3. 发明申请
    • COMPOSITIONS AND METHODS FOR MODULATION OF RORGAMMAT FUNCTIONS
    • 组合物和方法用于调制罗格玛函数
    • US20150218563A1
    • 2015-08-06
    • US14589336
    • 2015-01-05
    • Dan LittmanGerard EberlLiang ZhouIvaylo Ivanov
    • Dan LittmanGerard EberlLiang ZhouIvaylo Ivanov
    • C12N15/113
    • C12N15/1138A61K39/0011A61K39/39A61K2039/55522C07K16/2803C12N2310/14C12N2310/531
    • The present invention relates to expression of RORγt in cells and tissues and the effect of expression of this gene on proliferation of specific immune cells and in promotion of immune cell aggregates and in induction of IL17 producing cells. Furthermore, the invention relates to methods and agents that may decrease function of the gene product (the protein) or expression of this gene in individuals experiencing an inflammatory condition, an autoimmune disease or a food allergy, or any other condition whereby it is desirable to inhibit an immune response. In addition, methods and agents useful for enhancing the function of RORγt with agonists or expression of this gene are also considered for use whereby it is desirable to increase immunity to a pathogen or tumor cell, for example, for use in conjunction with a vaccine. Screening methods for identifying novel modulators (antagonists and agonists) of RORγt are also disclosed.
    • 本发明涉及细胞和组织中RORγt的表达以及该基因表达对特异性免疫细胞增殖和促进免疫细胞聚集和诱导IL17产生细胞的作用。 此外,本发明涉及可以减少经历炎症状况,自身免疫疾病或食物过敏的个体的基因产物(蛋白质)或该基因的表达或其他任何其它条件的功能的方法和试剂, 抑制免疫反应。 此外,还考虑用于增强RORγt与激动剂或该基因表达的功能的方法和试剂,因此期望提高对病原体或肿瘤细胞的免疫力,例如与疫苗结合使用。 还公开了用于鉴定RORγt的新型调节剂(拮抗剂和激动剂)的筛选方法。
    • 4. 发明授权
    • Wireless communication system, device and method
    • 无线通信系统,设备和方法
    • US08737510B2
    • 2014-05-27
    • US13160723
    • 2011-06-15
    • Liang Zhou
    • Liang Zhou
    • H04B7/02
    • H04B7/0691H04B1/71072H04B7/0413
    • A wireless communication system includes an inverse matrix calculating unit which uses an inverse matrix of a channel matrix of a first combination of L antennas (where L is an integer, 1≦L≦N) selected from the N antennas, so as to calculate an inverse matrix of a channel matrix of a second combination of L antennas selected from the N antennas through an arithmetic operation, and an antenna selecting unit which selects a combination of L antennas from the N antennas as L antennas to be used for communication, the selected combination determining a reference value for antenna selection related to the inverse matrix calculated by the inverse matrix calculating unit so that the reference value for antenna selection fits a successive interference cancellation process carried out for a signal transmitted from the L antennas of the selected combination.
    • 无线通信系统包括逆矩阵计算单元,该逆矩阵计算单元使用从N个天线中选择的L个天线(其中L是整数,1≦̸ L≦̸ N)的第一组合的信道矩阵的逆矩阵,以计算 通过算术运算从N个天线选择的L个天线的第二组合的信道矩阵的逆矩阵,以及天线选择单元,其从N个天线中选择L个天线的组合作为用于通信的L个天线,所选择的 组合确定与由逆矩阵计算单元计算的逆矩阵相关的天线选择的参考值,使得用于天线选择的参考值适合对从所选择的组合的L个天线发射的信号执行的连续干扰消除处理。
    • 5. 发明授权
    • MIMO-OFDM communication system and communication method of same
    • MIMO-OFDM通信系统及其通信方法相同
    • US08351524B2
    • 2013-01-08
    • US12470249
    • 2009-05-21
    • Liang Zhou
    • Liang Zhou
    • H04K1/10H04L27/28
    • H04B7/0417H04B7/0854H04L25/03343H04L27/2608H04L2025/03414
    • A MIMO-OFDM communication method for transmitting and receiving data using MIMO-OFDM communication has, on the transmitting side, a step of performing precoding processing of transmission data using a prescribed precoding method, and a step of performing OFDM modulation of the precoding-processed data and transmitting the data from a plurality of transmission antennas, and has, on the receiving side, a step of performing MIMO decoding processing of reception signals received by a plurality of reception antennas according to a ZF decoding algorithm or an MMSE decoding algorithm, and outputting the data as a transmission data stream, a step of calculating weighting coefficients according to the precoding method, and a step of performing weighted decoding processing of the transmission data obtained by the MIMO decoding processing, by multiplying path metric of the decoding processing by the weighting coefficients.
    • 用于使用MIMO-OFDM通信发送和接收数据的MIMO-OFDM通信方法在发送侧具有使用规定的预编码方法进行发送数据的预编码处理的步骤,以及执行预编码处理的OFDM调制的步骤 数据并从多个发送天线发送数据,并且在接收侧具有根据ZF解码算法或MMSE解码算法对由多个接收天线接收的接收信号进行MIMO解码处理的步骤,以及 输出作为传输数据流的数据,根据预编码方法计算加权系数的步骤,以及对通过MIMO解码处理获得的传输数据进行加权解码处理的步骤,通过将解码处理的路径度量乘以 加权系数。
    • 6. 发明授权
    • Radio communication method, transmitter, and receiver
    • 无线电通信方式,发射机和接收机
    • US07873113B2
    • 2011-01-18
    • US11889544
    • 2007-08-14
    • Takeshi TakanoLiang Zhou
    • Takeshi TakanoLiang Zhou
    • H04L1/02
    • H04B7/0691H04B7/0417H04B7/043H04B7/061H04B7/0634H04B7/0639H04B7/0689H04B7/0697H04B7/0874
    • Of the antenna group composed of multiple ones of the transmission antennas and multiple ones of the reception antennas, the present method selects an antenna group which satisfies a first criterion relating to communication quality. Out of combinations of transmission antennas and reception antennas included in the selected antenna group, combinations which satisfy a second criterion relating to communication quality are selected. Using a part of or all of the selected combinations of transmission antennas and reception antennas, the above-mentioned communication is performed. As a result, selection of optimal transmission antennas and reception antennas according to radio communication environment can be performed with high speed with a smaller amount of operation amount than the previous art.
    • 在由多个发送天线和多个接收天线组成的天线组中,本方法选择满足与通信质量有关的第一标准的天线组。 在所选择的天线组中包括的发送天线和接收天线的组合中,选择满足与通信质量有关的第二准则的组合。 使用所选择的发送天线和接收天线的组合的一部分或全部,执行上述通信。 结果,可以以比现有技术更少量的操作量以高速度执行根据无线电通信环境的最佳发送天线和接收天线的选择。
    • 8. 发明授权
    • Circuit for synchronizing symbols of OFDM signal
    • 用于同步OFDM信号符号的电路
    • US07720106B2
    • 2010-05-18
    • US10926035
    • 2004-08-26
    • Liang Zhou
    • Liang Zhou
    • H04J3/06H04L7/00
    • H04L27/2665H04L27/2662
    • A circuit for synchronizing symbols of a received OFDM signal includes a unit configured to detect cross-correlation of a received signal to generate a value of the cross-correlation, a unit configured to obtain synchronous summation of the value of the cross-correlation performed at predetermined intervals, a unit configured to obtain received electric power of the received signal, an autocorrelation electric power obtaining unit configured to obtain autocorrelation electric power of the received signal, a threshold obtaining unit configured to obtain a synchronous summation threshold responsive to the received electric power, and a symbol timing detecting unit configured to identify timing of a peak of the synchronous summation as symbol timing in response to detecting, at the timing of the peak, that the autocorrelation electric power is smaller than the received electric power multiplied by a predetermined factor and that the synchronous summation is larger than the synchronous summation threshold.
    • 用于同步接收的OFDM信号的符号的电路包括被配置为检测接收信号的互相关以产生互相关值的单元,被配置为获得在互相关执行的互相关的值的同步求和的单元 预定间隔,被配置为获得接收信号的接收电力的单元;被配置为获得接收信号的自相关电力的自相关电力获取单元;阈值获取单元,被配置为响应于所接收的电力获得同步求和阈值 以及符号定时检测单元,被配置为响应于在所述峰值的定时检测到所述自相关电力小于所接收的电力乘以预定因子的响应来识别所述同步求和的峰值的定时作为符号定时 并且同步求和大于同步和 配合阈值