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    • 2. 发明授权
    • Method for estimating changes of cardiovascular indices using peripheal arterial blood pressure waveform
    • 使用周围动脉血压波形估算心血管指数变化的方法
    • US09560977B2
    • 2017-02-07
    • US14315741
    • 2014-06-26
    • Massachusetts Institute of Technology
    • Richard Jonathan CohenKichang LeeTatsuya Arai
    • A61B5/02A61B5/021A61B5/029
    • A61B5/021A61B5/02028A61B5/029
    • The systems and methods described herein enable reliable estimation of cardiovascular indices on real-time, non-invasive or minimally-invasive, and beat-to-beat basis. Cardiovascular indices which can be estimated include: stroke volume (SV), which being limited to, cardiac output (CO) and total peripheral resistance (TPR). In various embodiments, one or more of these indices are estimated continuously, on a beat-to-beat basis, using peripheral arterial blood pressure (ABP) waveforms and certain parameters derived from the peripheral ABP waveforms. The derived parameters are substantially insensitive to distortions of the ABP waveform arising from tapered arterial branches throughout the arterial tree. The methods describe herein can provide a more accurate and reliable estimate of hemodynamic parameters than existing techniques.
    • 本文所述的系统和方法能够可靠地估计心脏指数的实时,非侵入性或微创和基于搏动的基准。 可以估计的心血管指数包括:中风量(SV),其限于心输出量(CO)和总外周阻力(TPR)。 在各种实施例中,使用外周动脉血压(ABP)波形和从外围ABP波形导出的某些参数,以搏动为基础连续地估计这些指标中的一个或多个。 导出的参数对于通过整个动脉树的锥形动脉分支产生的ABP波形的变形基本上不敏感。 本文描述的方法可以提供比现有技术更准确和可靠的血液动力学参数估计。