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    • 2. 发明申请
    • OPTICAL CALIBRATION SYSTEM AND METHOD
    • 光学校准系统和方法
    • US20080144035A1
    • 2008-06-19
    • US11610059
    • 2006-12-13
    • Lloyd G. AllredMing Lai
    • Lloyd G. AllredMing Lai
    • G01N21/47
    • A61B3/1005A61B3/0025
    • An optical system calibration system and method particularly suited for calibrating the optical slit planes in an ophthalmic diagnostic instrument. The system includes an illumination source projector, an illumination image receiver, and a calibration component all having known relative positions, orientations and physical and optical characteristics. The calibration component includes at least two separated, diffusely reflecting surfaces. Images of an exemplary slit illumination pattern projected onto the calibration component and formed on the diffusely reflecting surfaces are detected by the image receiver such as a video camera. Based upon camera image coordinates and triangulation parameters of the projector, the receiver, and the calibration component, the slit image positions on the image detector plane can be calibrated to the axially displaced, diffusely reflecting calibration component surface positions.
    • 一种特别适用于校准眼科诊断仪器中的光学狭缝平面的光学系统校准系统和方法。 该系统包括具有已知的相对位置,取向和物理和光学特性的照明源投影仪,照明图像接收器和校准组件。 校准组件包括至少两个分开的漫反射表面。 通过诸如摄像机的图像接收器检测投影到校准部件上并形成在漫反射表面上的示例性狭缝照射图案的图像。 基于投影仪,接收器和校准组件的相机图像坐标和三角测量参数,可以将图像检测器平面上的狭缝图像位置校准为轴向移位的漫反射校准部件表面位置。
    • 4. 发明授权
    • Optical calibration system and method
    • 光学校准系统及方法
    • US07859677B2
    • 2010-12-28
    • US11610059
    • 2006-12-13
    • Ming LaiLloyd G. Allred
    • Ming LaiLloyd G. Allred
    • G01N21/47
    • A61B3/1005A61B3/0025
    • An optical system calibration system and method particularly suited for calibrating the optical slit planes in an ophthalmic diagnostic instrument. The system includes an illumination source projector, an illumination image receiver, and a calibration component all having known relative positions, orientations and physical and optical characteristics. The calibration component includes at least two separated, diffusely reflecting surfaces. Images of an exemplary slit illumination pattern projected onto the calibration component and formed on the diffusely reflecting surfaces are detected by the image receiver such as a video camera. Based upon camera image coordinates and triangulation parameters of the projector, the receiver, and the calibration component, the slit image positions on the image detector plane can be calibrated to the axially displaced, diffusely reflecting calibration component surface positions.
    • 一种特别适用于校准眼科诊断仪器中的光学狭缝平面的光学系统校准系统和方法。 该系统包括具有已知的相对位置,取向和物理和光学特性的照明源投影仪,照明图像接收器和校准组件。 校准组件包括至少两个分开的漫反射表面。 通过诸如摄像机的图像接收器检测投影到校准部件上并形成在漫反射表面上的示例性狭缝照射图案的图像。 基于投影仪,接收器和校准组件的相机图像坐标和三角测量参数,可以将图像检测器平面上的狭缝图像位置校准为轴向移位的漫反射校准部件表面位置。
    • 5. 发明申请
    • Ophthalmic Aberrometer Capable of Subjective Refraction
    • 具有主观折射能力的眼科测试仪
    • US20140176904A1
    • 2014-06-26
    • US14076276
    • 2013-11-11
    • Ming Lai
    • Ming Lai
    • A61B3/103
    • A61B3/1035
    • The present invention contemplates an ophthalmic aberrometer combining measurements of wavefront aberrations and subjective refraction into a single instrument and refers both measurements to the same corneal plane The present invention also contemplates an ophthalmic aberrometer employing an open field and subjective correction to overcome instrument myopia and to ensure accurate measurement of the best-corrected visual acuity in addition to measurement of wavefront aberrations. The present invention further contemplates an ophthalmic aberrometer implementing an optical relay with adjustable optical power compensation to eliminate the need for flipping plurality sets of trial lenses for defocus correction. The present invention also further contemplates an ophthalmic aberrometer making wavefront measurement along a viewing path of the subject eye and enabling accurate measurement of the residual wavefront aberrations after compensating for the subjective refraction.
    • 本发明考虑了将眼波像差和主观折射的测量结合到单个仪器中并将两个测量结合到同一角膜平面上的眼科像差仪。本发明还考虑采用开放场和主观矫正以克服仪器近视并确保 除了测量波前像差以外,精确测量最佳矫正视力。 本发明进一步考虑了一种实现具有可调光功率补偿的光学继电器的眼科畸变器,以消除对多组试镜进行离焦校正的翻转的需要。 本发明还进一步考虑了一种眼科像差仪,沿着被检眼的观察路线进行波前测量,并且能够在补偿主观折射之后准确测量残留波前像差。
    • 6. 发明授权
    • Apparatus and method for soft tissue ablation employing high power diode-pumped laser
    • 使用高功率二极管泵浦激光的软组织消融的装置和方法
    • US08137340B2
    • 2012-03-20
    • US11155079
    • 2005-06-17
    • Ming LaiLiyue MuKangze CaiWeiguo Luo
    • Ming LaiLiyue MuKangze CaiWeiguo Luo
    • A61B18/18
    • A61B18/22A61B2018/2272
    • The present invention discloses a high power diode-pumped laser for laser ablation of soft tissue. The present invention contemplates to operate the high power diode-pumped solid-state laser at a continuous Q-switching mode and at a big number of transverse modes. The present invention also contemplates to reduce beam divergence and beam spot size and thus to increase power density of the laser on target tissue to improve the speed of tissue ablation. The present invention further contemplates to minimize power consumption such that external water-cooling or secondary cooling loop can be eliminated. The present invention even further contemplates to implement combined mechanisms to protect intracavity optics from power damage. Finally, the present invention contemplates hospitals and surgeon offices to use the high power diode-pumped laser for soft tissue ablation with standard electrical wall-plug outlet and elimination of inconvenient external water-cooling or secondary cooling loop.
    • 本发明公开了一种用于软组织激光烧蚀的高功率二极管泵浦激光器。 本发明考虑以连续Q开关模式和大量横向模式操作高功率二极管泵浦固态激光器。 本发明还考虑减少光束发散和光斑尺寸,从而增加激光在靶组织上的功率密度,以提高组织消融的速度。 本发明进一步考虑到最小化功率消耗,使得可以消除外部水冷或二次冷却回路。 本发明甚至进一步设想实现组合机构以保护腔内光学器件免受功率损坏。 最后,本发明考虑到医院和外科医生办公室将高功率二极管泵浦激光器用于具有标准电壁插座出口的软组织消融,并消除了不方便的外部水冷或二次冷却回路。
    • 7. 发明申请
    • Corneal measurement apparatus and a method of using the same
    • 角膜测量装置及其使用方法
    • US20080212030A1
    • 2008-09-04
    • US11955001
    • 2007-12-12
    • Joseph R. BentleyMing Lai
    • Joseph R. BentleyMing Lai
    • A61B3/107
    • A61B3/107A61B3/1005A61B3/135
    • An apparatus for measuring a subject's cornea, comprising (A.) a slit projection subsystem comprising a light source, (B.) a mask subsystem disposed in a path of light from the light source, comprising a first slit mask defining a plurality of apertures, (C.) a movement apparatus adapted to move at least a portion of the slit projection subsystem, the movement apparatus configured and arranged such that, by moving the portion of the slit projection subsystem, portions of the light can be selectively transmitted through an aperture of the plurality of apertures toward the cornea, (D.) an imaging element configured and arranged to image at least one of the plurality of apertures onto the cornea, and (E.) an image capture subsystem arranged to capture images of the portions of light after the light impinges on the cornea.
    • 一种用于测量被检者的角膜的装置,包括(A.)狭缝投影子系统,包括光源,(B)设置在来自光源的光的路径中的掩模子系统,包括限定多个孔的第一狭缝掩模 ,(C)适于移动所述狭缝投影子系统的至少一部分的移动装置,所述移动装置被配置和布置成使得通过移动所述狭缝投影子系统的所述部分,所述光的一部分可以选择性地透过 (D)成像元件,其被配置和布置成将所述多个孔中的至少一个孔映射到所述角膜上,以及(E)被配置为捕获所述部分的图像的图像捕获子系统 在光线撞击角膜后的光线。
    • 10. 发明授权
    • Method and apparatus for measuring a corneal profile of an eye
    • 用于测量眼睛角膜轮廓的方法和装置
    • US06575573B2
    • 2003-06-10
    • US09981054
    • 2001-10-17
    • Ming LaiJing-Gang XieJay Wei
    • Ming LaiJing-Gang XieJay Wei
    • A61B310
    • A61B3/107
    • Embodiments of the present invention provide a method and apparatus for measurement of a corneal profile of an eye. In particular, one embodiment of the present invention is a corneal diagnostic instrument including: (a) a Placido ring illuminator disposed to project radiation onto a cornea to generate a Placido ring image; (b) multiple slit lamp projectors disposed to project slit light beam images onto the cornea to generate slit light beam images; (c) a camera system optically disposed to detect the Placido ring image and the slit light beam images; and (d) a controller, coupled to the slit lamp projectors, the Placido ring illuminator, and the camera system, to cause the slit light beam images and the Placido ring image to be generated and detected in a predetermined sequence, wherein the controller is responsive to the detected Placido ring image and the detected slit light beam images to determine a corneal thickness profile.
    • 本发明的实施例提供了一种用于测量眼睛角膜轮廓的方法和装置。 特别地,本发明的一个实施例是角膜诊断仪器,其包括:(a)布置的环形照明器,其布置成将辐射投射到角膜上以产生普拉西多环图像; (b)多个狭缝灯投影仪,其设置成将狭缝光束图像投射到角膜上以产生狭缝光束图像; (c)光学设置以检测普拉西多环图像和狭缝光束图像的照相机系统; 以及(d)控制器,其耦合到裂隙灯投影仪,普拉西多环照明器和相机系统,以使预定顺序产生和检测狭缝光束图像和普拉西多环形图像,其中控制器是 响应于检测到的Placido环图像和检测到的狭缝光束图像以确定角膜厚度分布。