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1. 发明授权

US11365375B2 Alpha-amylase variants and polynucleotides encoding same 有权
公开(公告)号：US11365375B2
公开(公告)日：2022-06-21
申请号：US16394265
申请日：2019-04-25
申请人： NOVOZYMES A/S
发明人： Carsten Andersen , Vivek Srivastava , Padmavathi Balumuri , Partha Pratim Chakrabarti , Sohel Dalal
IPC分类号： C11D3/386 , C12N9/28
摘要： The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

2. 发明申请

US20210130743A1 Mannanase Variants and Polynucleotides Encoding Same 有权
公开(公告)号：US20210130743A1
公开(公告)日：2021-05-06
申请号：US16605091
申请日：2018-04-26
申请人： Novozymes A/S
发明人： Vivek Srivastava , Markus Klinger , Rakhi Saikia , Vijaya Shankar Nataraj , Sohel Dalal , Jens Erik Nielsen
IPC分类号： C11D3/386 , C11D11/00 , C12N9/24
摘要： The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

3. 发明申请

US20180298456A1 GLUCOAMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
公开(公告)号：US20180298456A1
公开(公告)日：2018-10-18
申请号：US15767551
申请日：2016-10-12
申请人： NOVOZYMES A/S
发明人： Shikha Gupta , Allan Svendsen , Vivek Srivastava , Marco Malten , Thomas Agersten Poulsen , Preethi Ramaiya , Beth Nelson , Vasudeva P. Rao , Padmavathi Balumuri
IPC分类号： C12P19/02 , C12P19/20 , C12N9/34 , C12P19/14
摘要： The present invention relates to glucoamylase variants having an increase in specific activity and/or an increase in melting temperature measured by TSA of at least 0.5 degrees Celsius, and further wherein the variants have at least at least 85%, at least 90%, at least 95% identity, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100%, sequence identity to the amino acid sequence of SEQ ID NO: 3. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

4. 发明授权

US11492605B2 Mannanase variants and polynucleotides encoding same 有权
公开(公告)号：US11492605B2
公开(公告)日：2022-11-08
申请号：US16605086
申请日：2018-04-26
申请人： Novozymes A/S
发明人： Vivek Srivastava , Markus Klinger , Rakhi Saikia , Vijaya Shankar Nataraj , Sohel Dalal , Jens Erik Nielsen , Rajendra Kulothungan Sainathan
IPC分类号： C12N9/42 , C11D3/386
摘要： The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

5. 发明授权

US11326153B2 Alpha-amylase variants and polynucleotides encoding same 有权
公开(公告)号：US11326153B2
公开(公告)日：2022-05-10
申请号：US16770797
申请日：2018-12-07
申请人： NOVOZYMES A/S
发明人： Carsten Andersen , Vasudeva Prahlada Rao , Rakhi Saikia , Vivek Srivastava , Kendra Darlene Stallings
IPC分类号： C12N9/28 , C12P19/02 , C12P19/14 , C13K1/06
摘要： The present invention relates to alpha-amylase variants comprising a substitution at a position corresponding to position 188 and at least one further substitution at a position corresponding to position 242 or 279 or 275 of SEQ ID NO: 1, in particular one or more combinations of substitutions selected from the group consisting of E188P+S242Y, E188P+S242F, E188P+S242H, E188P+S242W, E188P+S242P, E188P+S242I, E188P+S242T, E188P+S242L, E188P+K279W, E188P+K279Y, E188P+K279F, E188P+K279H, E188P+K279I, E188P+K279L, E188P+K279D, E188P+K279M, E188P+K279S, E188P+K279T E188P+K279N, E188P+K279Q, E188P+K279V, E188P+K279A, E188P+N275F, E188P+N275Y, E188P+N275W, and E188P+N275H, wherein the variant has at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100% sequence identity to a parent alpha amylase selected from the group consisting of: SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, and SEQ ID NO: 27. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

6. 发明申请

US20190249119A1 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 审中-公开
公开(公告)号：US20190249119A1
公开(公告)日：2019-08-15
申请号：US16394265
申请日：2019-04-25
申请人： NOVOZYMES A/S
发明人： Carsten Andersen , Vivek Srivastava , Padmavathi Balumuri , Partha Pratim Chakrabarti , Sohel Dalal
IPC分类号： C11D3/386 , C12N9/28
CPC分类号： C11D3/38681 , C11D3/386 , C11D3/38627 , C11D3/38645 , C11D3/38654 , C11D3/38663 , C12N9/2417 , C12Y302/01001
摘要： The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

7. 发明授权

US10316275B2 Alpha-amylase variants and polynucleotides encoding same 有权
公开(公告)号：US10316275B2
公开(公告)日：2019-06-11
申请号：US15571193
申请日：2016-05-09
申请人： NOVOZYMES A/S
发明人： Carsten Andersen , Vivek Srivastava , Padmavathi Balumuri , Partha Pratim Chakrabarti , Sohel Dalal
IPC分类号： C11D3/386 , C12N9/28
摘要： The present invention relates to alpha-amylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

8. 发明授权

US11203790B2 Glucoamylase variants and polynucleotides encoding same 有权
公开(公告)号：US11203790B2
公开(公告)日：2021-12-21
申请号：US16656708
申请日：2019-10-18
申请人： NOVOZYMES A/S
发明人： Shikha Gupta , Allan Svendsen , Vivek Srivastava , Marco Malten , Thomas Agersten Poulsen , Preethi Ramaiya , Beth Nelson , Vasudeva Prahlada Rao , Padmavathi Balumuri
IPC分类号： C12P19/02 , C12P19/14 , C12P19/20 , C12N9/34
摘要： The present invention relates to glucoamylase variants, polynucleotides encoding the variants, methods of producing the variants, and methods of using the variants. Also described are the use of glucoamylases of the invention for starch conversion to produce fermentation products, such as ethanol, and syrups, such as glucose. The invention also relates to a composition comprising a glucoamylase variant of the invention.

9. 发明申请

US20210189364A1 ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME 有权
公开(公告)号：US20210189364A1
公开(公告)日：2021-06-24
申请号：US16770797
申请日：2018-12-07
申请人： NOVOZYMES A/S
发明人： Carsten Andersen , Vasudeva Prahlada Rao , Rakhi Saikia , Vivek Srivastava , Kendra Darlene Stallings
IPC分类号： C12N9/28 , C12P19/14 , C12P19/02 , C13K1/06
摘要： The present invention relates to alpha-amylase variants comprising a substitution at a position corresponding to position 188 and at least one further substitution at a position corresponding to position 242 or 279 or 275 of SEQ ID NO: 1, in particular one or more combinations of substitutions selected from the group consisting of E188P+S242Y, E188P+S242F, E188P+S242H, E188P+S242W, E188P+S242P, E188P+S242I, E188P+S242T, E188P+S242L, E188P+K279W, E188P+K279Y, E188P+K279F, E188P+K279H, E188P+K279I, E188P+K279L, E188P+K279D, E188P+K279M, E188P+K279S, E188P+K279T E188P+K279N, E188P+K279Q, E188P+K279V, E188P+K279A, E188P+N275F, E188P+N275Y, E188P+N275W, and E188P+N275H, wherein the variant has at least 60%, at least 65%, at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98%, or at least 99%, but less than 100% sequence identity to a parent alpha amylase selected from the group consisting of: SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 14, SEQ ID NO: 15, SEQ ID NO: 16, SEQ ID NO: 17, SEQ ID NO: 18, and SEQ ID NO: 27. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

10. 发明申请

US20210130801A1 Mannanase Variants and Polynucleotides Encoding Same 有权
公开(公告)号：US20210130801A1
公开(公告)日：2021-05-06
申请号：US16605086
申请日：2018-04-26
申请人： Novozymes A/S
发明人： Vivek Srivastava , Markus Klinger , Rakhi Saikia , Vijaya Shankar Nataraj , Sohel Dalal , Jens Erik Nielsen , Rajendra Kulothungan Sainathan
IPC分类号： C12N9/42 , C11D3/386
摘要： The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

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