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    • 3. 发明申请
    • Microwave-based examination using hypothesis testing
    • 基于微波检验的假设检验
    • US20060058606A1
    • 2006-03-16
    • US10942115
    • 2004-09-15
    • Shakti DavisSusan HagnessBarry Van Veen
    • Shakti DavisSusan HagnessBarry Van Veen
    • A61B5/05
    • A61B5/05A61B5/0507A61B6/502A61B2562/143
    • Microwave examination of individuals is carried out by transmitting microwave signals from multiple antenna locations into an individual and receiving the backscattered microwave signals at multiple antenna locations to provide received signals from the antennas. The received signals are processed to remove the skin interface reflection component of the signal and the corrected signal data are provided to a hypothesis testing process. In hypothesis testing for detecting tumors, image data are formed from the test statistic used to perform a binary hypothesis test at each voxel. The null hypothesis asserts that no tumor is present at a candidate voxel location. The voxel threshold is determined by specifying a false discovery rate to control the expected proportion of false positives in the image. When the test statistic value associated with a voxel is greater than the threshold, the null hypothesis is rejected and the test statistic is assigned to the voxel. For voxels where the test statistic falls below the threshold, the null hypothesis is accepted and the voxel value is set to zero. The resulting image indicates the locations or other characteristics of detected tumors.
    • 通过将来自多个天线位置的微波信号发射到个体中并且在多个天线位置处接收背向散射的微波信号以提供来自天线的接收信号来进行个体的微波检查。 处理接收到的信号以去除信号的皮肤界面反射分量,并将校正的信号数据提供给假设检验过程。 在用于检测肿瘤的假设检验中,从用于在每个体素执行二进制假设检验的检验统计量形成图像数据。 零假设声称在候选体素位置没有肿瘤存在。 通过指定虚拟发现速率来控制图像中的假阳性预期比例来确定体素阈值。 当与体素相关联的测试统计值大于阈值时,零假设被拒绝,并且测试统计量被分配给体素。 对于测试统计量低于阈值的体素,接受零假设,并将体素值设置为零。 所得到的图像指示检测到的肿瘤的位置或其他特征。
    • 6. 发明申请
    • Time domain inverse scattering techniques for use in microwave imaging
    • 用于微波成像的时域反散射技术
    • US20060241409A1
    • 2006-10-26
    • US11056342
    • 2005-02-11
    • David WintersBarry Van VeenSusan Hagness
    • David WintersBarry Van VeenSusan Hagness
    • A61B5/05
    • A61B5/05
    • A system and a method are provided for estimating the average dielectric properties of a plurality of regions in space. The application of this technique is illustrated for determining the average properties of breast tissue. The knowledge of average properties is important when UWB microwave radar signal processing algorithms are used for tumor detection and localization. The method is an extension of a time-domain inverse scattering algorithm based on the finite-difference time-domain method. A hybrid conjugate gradient optimization is used to minimize a cost function defined between a measured and a calculated total electromagnetic field at a series of antennas. The output of the method is an average set of electromagnetic material parameters that describe specific regions of interest in either a non-dispersive heterogeneous medium or a dispersive heterogeneous medium.
    • 提供一种用于估计空间中的多个区域的平均介电性质的系统和方法。 说明了该技术的应用以确定乳房组织的平均性质。 当UWB微波雷达信号处理算法用于肿瘤检测和定位时,平均属性的知识很重要。 该方法是基于有限差分时域法的时域逆散射算法的扩展。 使用混合共轭梯度优化来最小化在一系列天线处测量的和计算的总电磁场之间定义的成本函数。 该方法的输出是在非分散不均匀介质或分散异质介质中描述特定感兴趣区域的平均电磁材料参数集。