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1. 发明申请

US20230125894A1 System and Method for Drug Detection in Exhaled Breath 有权
公开(公告)号：US20230125894A1
公开(公告)日：2023-04-27
申请号：US18088439
申请日：2022-12-23
申请人： Sensa Bues AB
发明人： Göran Palmskog , Olof Beck
IPC分类号： G01N21/65 , A61B5/08 , A61B5/00 , G01N33/497 , F01D1/08 , F01D5/04 , A61B5/097 , G01J3/44
摘要： A portable system is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit and a housing arranged to hold the sampling unit, the sampling unit is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing has at least one inlet for the subject to exhale into the housing to the sampling unit and at least one outlet for the exhaled breath to exit through.

2. 发明授权

US08705029B2 System and method for detection of analytes in exhaled breath 有权
标题翻译：用于检测呼气中分析物的系统和方法
公开(公告)号：US08705029B2
公开(公告)日：2014-04-22
申请号：US13739607
申请日：2013-01-11
申请人： Sensa Bues AB
发明人： Göran Palmskog , Olof Beck , Per Ola Andersson
IPC分类号： G01J3/44
CPC分类号： G01N21/658 , A61B5/082 , A61B5/412 , G01J3/44 , G01N33/497
摘要： A device, system, and methods are disclosed for detecting the presence or determining a quantitative amount of at least one drug substance from exhaled breath of a subject in-situ. A collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer that comprises at least one SERS-active material. The collecting surface is arranged as an outer surface of a waveguide for contact with exhaled breath, such that at least traces of said at least one drug substance in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum that is detected in-situ for said detecting the presence or determining the quantitative amount of said at least one drug substance from said exhaled breath.
摘要翻译：公开了一种装置，系统和方法，用于从现场呼出的呼吸气体中检测存在或确定至少一种药物的定量。收集表面具有包含至少一种SERS活性材料的表面增强拉曼光谱（SERS）活性层。收集表面被布置为用于与呼出气体接触的波导的外表面，使得所述呼出的呼吸中的至少一种药物物质的至少痕迹可接触所述SERS活性层以读出拉曼位移谱其被现场检测，用于从所述呼出的呼吸中检测存在或确定所述至少一种药物的定量。

3. 发明申请

US20130128260A1 System and Method for Detection of Analytes in Exhaled Breath 有权
标题翻译：用于检测呼气中分析物的系统和方法
公开(公告)号：US20130128260A1
公开(公告)日：2013-05-23
申请号：US13739607
申请日：2013-01-11
申请人： Sensa Bues AB
发明人： Göran Palmskog , Olof Beck , Per Ola Andersson
IPC分类号： G01J3/44
CPC分类号： G01N21/658 , A61B5/082 , A61B5/412 , G01J3/44 , G01N33/497
摘要： A device, system, and methods are disclosed for detecting the presence or determining a quantitative amount of at least one drug substance from exhaled breath of a subject in-situ. A collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer that comprises at least one SERS-active material. The collecting surface is arranged as an outer surface of a waveguide for contact with exhaled breath, such that at least traces of said at least one drug substance in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum that is detected in-situ for said detecting the presence or determining the quantitative amount of said at least one drug substance from said exhaled breath.
摘要翻译：公开了一种装置，系统和方法，用于从现场呼出的呼吸气体中检测存在或确定至少一种药物的定量。收集表面具有包含至少一种SERS活性材料的表面增强拉曼光谱（SERS）活性层。收集表面被布置为用于与呼出气体接触的波导的外表面，使得所述呼出的呼吸中的至少一种药物物质的至少痕迹可接触所述SERS活性层以读出拉曼位移谱其被现场检测，用于从所述呼出的呼吸中检测存在或确定所述至少一种药物的定量。

4. 发明授权

US11567011B2 System and method for drug detection in exhaled breath 有权
公开(公告)号：US11567011B2
公开(公告)日：2023-01-31
申请号：US16678761
申请日：2019-11-08
申请人： Sensa Bues AB
发明人： Göran Palmskog , Olof Beck
IPC分类号： A61B5/08 , A61B5/097 , G01N21/65 , A61B5/00 , G01N33/497 , F01D1/08 , F01D5/04 , G01J3/44
摘要： A portable system is disclosed for collecting a sample from exhaled breath of a subject. Drug substance in the exhaled breath are detected or determined. The sample is collected for further analysis using mass-spectroscopy. The system comprises a sampling unit and a housing arranged to hold the sampling unit, the sampling unit is adapted to collect non-volatile and volatile compounds of the at least one drug substance from the exhaled breath from the subject. The housing has at least one inlet for the subject to exhale into the housing to the sampling unit and at least one outlet for the exhaled breath to exit through.

5. 发明申请

US20140204374A1 System and Method for Detection of Analytes in Exhaled Breath 审中-公开
标题翻译：用于检测呼气中分析物的系统和方法
公开(公告)号：US20140204374A1
公开(公告)日：2014-07-24
申请号：US14222696
申请日：2014-03-24
申请人： Sensa Bues AB
发明人： Göran Palmskog , Olof Beck , Per Ola Andersson
IPC分类号： G01N21/65
CPC分类号： G01N21/658 , A61B5/082 , A61B5/412 , G01J3/44 , G01N33/497
摘要： A device, system, and methods are disclosed for detecting the presence or determining a quantitative amount of at least one drug substance from exhaled breath of a subject in-situ. A collecting surface has a Surface Enhanced Raman Spectroscopy (SERS)-active layer that comprises at least one SERS-active material. The collecting surface is arranged as an outer surface of a waveguide for contact with exhaled breath, such that at least traces of said at least one drug substance in said exhaled breath can contact said SERS-active layer for read-out of a Raman shift spectrum that is detected in-situ for said detecting the presence or determining the quantitative amount of said at least one drug substance from said exhaled breath.
摘要翻译：公开了一种装置，系统和方法，用于从现场呼出的呼吸气体中检测存在或确定至少一种药物的定量。收集表面具有包含至少一种SERS活性材料的表面增强拉曼光谱（SERS）活性层。收集表面被布置为用于与呼出气体接触的波导的外表面，使得所述呼出的呼吸中的至少一种药物物质的至少痕迹可接触所述SERS活性层以读出拉曼位移谱其被现场检测，用于从所述呼出的呼吸中检测存在或确定所述至少一种药物的定量。

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