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1. 发明授权

US08839384B2 Propagating user privacy preferences across multiple applications 有权
标题翻译：跨多个应用程序传播用户隐私偏好
公开(公告)号：US08839384B2
公开(公告)日：2014-09-16
申请号：US12873394
申请日：2010-09-01
申请人： Siddhartha Roy , Sijian Zhang , Michael Elizarov , Shaoyu Zhou , Fei Cao
发明人： Siddhartha Roy , Sijian Zhang , Michael Elizarov , Shaoyu Zhou , Fei Cao
IPC分类号： G06F7/04 , G06F21/62 , G06F21/60 , H04L29/06
CPC分类号： G06F21/6245 , G06F21/604 , G06F21/6209 , H04L63/102
摘要： Methods and systems for maintaining user privacy preferences based on one or more user identifications across a plurality of applications are provided. Two or more user identifications are received with associated user privacy preferences. The received user identification is compared against other user identifications to determine if the user identifications relate to the same user. It may be determined that two user identifications are related if they have at least one browser property in common. A consolidated data stream of the user privacy preferences for the related user identifications is created. The consolidated data stream is communicated to one or more applications and propagated to maintain the user privacy preferences across the applications relating to the user identification.
摘要翻译：提供了用于基于多个应用程序中的一个或多个用户标识来维护用户隐私偏好的方法和系统。接收到具有相关联的用户隐私偏好的两个或多个用户标识。将接收的用户标识与其他用户标识进行比较，以确定用户标识是否与同一用户相关。如果它们具有至少一个共同的浏览器属性，则可以确定两个用户标识相关。创建用于相关用户标识的用户隐私偏好的统一数据流。整合的数据流被传送到一个或多个应用，并被传播以保持与用户标识有关的应用的用户隐私偏好。

2. 发明授权

US08572239B2 Node clustering 有权
标题翻译：节点集群
公开(公告)号：US08572239B2
公开(公告)日：2013-10-29
申请号：US12885897
申请日：2010-09-20
申请人： Fei Cao , Shaoyu Zhou , Zhuoqing Wu, Jr. , Sijian Zhang , Siddhartha Roy , Michael A. Elizarov
发明人： Fei Cao , Shaoyu Zhou , Zhuoqing Wu, Jr. , Sijian Zhang , Siddhartha Roy , Michael A. Elizarov
IPC分类号： G06F15/177 , G06F15/16
CPC分类号： G06Q30/02 , G06Q30/0201
摘要： Large sets of unorganized data may provide little value in identifying useful observations from such data. For example, an online merchant may maintain a database of millions of user IDs (e.g., a cookie ID, a login ID, a device ID, a network ID, etc.) along with content viewed and/or actions taken with the user IDs, where minimal associations are known between user IDs. It may be advantageous to link together user IDs of respective users to capture a comprehensive view of respective users' activities. Accordingly, one or more systems and/or techniques for identifying a cluster of nodes based upon transforming a set of node pairings (e.g., pairings of related nodes) one or more times are disclosed herein. Iterative transformations may be performed until respective nodes are paired with merely their smallest neighboring node and are paired with no other node. In this way, node clusters may be identifiable.
摘要翻译：大量无组织数据可能无法从这些数据中识别有用的观察结果。例如，在线商家可以维护数百万用户ID的数据库（例如，Cookie ID，登录ID，设备ID，网络ID等）以及与用户ID一起观看的内容和/或所采取的动作其中用户ID之间的最小关联是已知的。链接各个用户的用户ID可能是有利的，以捕获各个用户的活动的综合视图。因此，本文公开了一种或多种用于基于将一组节点配对（例如，相关节点的配对）一次或多次来识别节点簇的一个或多个系统和/或技术。可以执行迭代变换，直到各个节点仅与其最小的相邻节点配对并且与没有其他节点配对。以这种方式，节点集群可以是可识别的。

3. 发明申请

US20120072554A1 NODE CLUSTERING 有权
标题翻译：节点聚类
公开(公告)号：US20120072554A1
公开(公告)日：2012-03-22
申请号：US12885897
申请日：2010-09-20
申请人： Fei Cao , Shaoyu Zhou , Zhuoqing Wu , Sijian Zhang , Siddhartha Roy , Michael A. Elizarov
发明人： Fei Cao , Shaoyu Zhou , Zhuoqing Wu , Sijian Zhang , Siddhartha Roy , Michael A. Elizarov
IPC分类号： G06F15/177 , G06F15/16
CPC分类号： G06Q30/02 , G06Q30/0201
摘要： Large sets of unorganized data may provide little value in identifying useful observations from such data. For example, an online merchant may maintain a database of millions of user IDs (e.g., a cookie ID, a login ID, a device ID, a network ID, etc.) along with content viewed and/or actions taken with the user IDs, where minimal associations are known between user IDs. It may be advantageous to link together user IDs of respective users to capture a comprehensive view of respective users' activities. Accordingly, one or more systems and/or techniques for identifying a cluster of nodes based upon transforming a set of node pairings (e.g., pairings of related nodes) one or more times are disclosed herein. Iterative transformations may be performed until respective nodes are paired with merely their smallest neighboring node and are paired with no other node. In this way, node clusters may be identifiable.
摘要翻译：大量无组织数据可能无法从这些数据中识别有用的观察结果。例如，在线商家可以维护数百万用户ID的数据库（例如，Cookie ID，登录ID，设备ID，网络ID等）以及与用户ID一起观看的内容和/或所采取的动作其中用户ID之间的最小关联是已知的。链接各个用户的用户ID可能是有利的，以捕获各个用户的活动的综合视图。因此，本文公开了一种或多种用于基于将一组节点配对（例如，相关节点的配对）一次或多次来识别节点簇的一个或多个系统和/或技术。可以执行迭代变换，直到各个节点仅与其最小的相邻节点配对并且与没有其他节点配对。以这种方式，节点集群可以是可识别的。

4. 发明授权

US08843394B2 Mapping identifiers 有权
标题翻译：映射标识符
公开(公告)号：US08843394B2
公开(公告)日：2014-09-23
申请号：US12818349
申请日：2010-06-18
申请人： Fei Cao , Shaoyu Zhou , Siddhartha Roy , Michael Elizarov , Zhuoqing Wu , James Zhang
发明人： Fei Cao , Shaoyu Zhou , Siddhartha Roy , Michael Elizarov , Zhuoqing Wu , James Zhang
IPC分类号： G06Q30/00 , G06Q30/02
CPC分类号： G06Q30/02 , G06Q30/0241 , G06Q30/0244 , G06Q30/0255
摘要： Systems and methods for mapping identifiers are provided. Activity logs illustrate activities and/or events associated with a plurality of identifiers. The identifiers may be registered identifiers, unregistered identifiers, or a combination thereof. When at least two identifiers share a linking attribute, the at least two identifiers may be mapped to one another, along with information associated therewith (if any) such as a user profile. Each subsequent line of an activity line may also be mapped to the identifiers of the initial single line when a linking attribute or an overlapping identifier is present. A number of identifiers associated with each other may be increased by mapping identifiers and, thus, a targeted audience for a customized advertisement may, in turn, be increased.
摘要翻译：提供了映射标识符的系统和方法。活动日志示出与多个标识符相关联的活动和/或事件。标识符可以是注册标识符，未注册标识符或其组合。当至少两个标识符共享链接属性时，可以将至少两个标识符与其相关联的信息（如果有的话）诸如用户简档映射到彼此。当存在链接属性或重叠标识符时，活动行的每个后续行也可以映射到初始单行的标识符。可以通过映射标识符来增加彼此关联的多个标识符，从而可以增加定制广告的目标受众。

5. 发明申请

US20110313847A1 MAPPING IDENTIFIERS 有权
标题翻译：映射标识符
公开(公告)号：US20110313847A1
公开(公告)日：2011-12-22
申请号：US12818349
申请日：2010-06-18
申请人： Fei Cao , Shaoyu Zhou , Siddhartha Roy , Michael Elizarov , Zhuoqing Wu , James Zhang
发明人： Fei Cao , Shaoyu Zhou , Siddhartha Roy , Michael Elizarov , Zhuoqing Wu , James Zhang
IPC分类号： G06Q30/00
CPC分类号： G06Q30/02 , G06Q30/0241 , G06Q30/0244 , G06Q30/0255
摘要： Systems and methods for mapping identifiers are provided. Activity logs illustrate activities and/or events associated with a plurality of identifiers. The identifiers may be registered identifiers, unregistered identifiers, or a combination thereof. When at least two identifiers share a linking attribute, the at least two identifiers may be mapped to one another, along with information associated therewith (if any) such as a user profile. Each subsequent line of an activity line may also be mapped to the identifiers of the initial single line when a linking attribute or an overlapping identifier is present. A number of identifiers associated with each other may be increased by mapping identifiers and, thus, a targeted audience for a customized advertisement may, in turn, be increased.
摘要翻译：提供了映射标识符的系统和方法。活动日志示出与多个标识符相关联的活动和/或事件。标识符可以是注册标识符，未注册标识符或其组合。当至少两个标识符共享链接属性时，可以将至少两个标识符与其相关联的信息（如果有的话）诸如用户简档映射到彼此。当存在链接属性或重叠标识符时，活动行的每个后续行也可以映射到初始单行的标识符。可以通过映射标识符来增加彼此关联的多个标识符，从而可以增加定制广告的目标受众。

6. 发明申请

US20140135393A1 SUBSTITUTED CATHECHOLS AS INHIBITORS OF IL-4 AND IL-5 FOR THE TREATMENT BRONCHIAL ASTHMA 审中-公开
标题翻译：作为IL-4和IL-5的抑制剂作为治疗性胆碱性哮喘的替代物
公开(公告)号：US20140135393A1
公开(公告)日：2014-05-15
申请号：US14110869
申请日：2012-04-11
申请人： Santu Bandyopadhyay , Balaram Ghosh , Parasuraman Jaisankar , Bikas Chandra Pal , Siddhartha Roy , Balaram Ghosh , Parasuraman Jaisankar , Bikas Pal , Nahid Ali , Siddhartha Roy , Bholanath Paul , Arjun Ram , Siddhartha Roy , Bholanath Paul , Arjun Ram , Ulaganathan Mabalirajan , Nahid Ali , Arun Bandopadhyay , Aditya Konar , Jayashree Bagchi Chakraborty , Indrani Chowdhury Mukherjee , Jaydeep Chaudhuri , Sanjit Kumar Mahato , Anirban Manna , Roma Sinha , Prayot Bhattacharya , Jayaraman Vinayagam , Deba Prasad Jana , Sushovan Chowdhury
发明人： Santu Bandyopadhyay , Balaram Ghosh , Parasuraman Jaisankar , Bikas Chandra Pal , Siddhartha Roy , Balaram Ghosh , Parasuraman Jaisankar , Bikas Pal , Nahid Ali , Siddhartha Roy , Bholanath Paul , Arjun Ram , Siddhartha Roy , Bholanath Paul , Arjun Ram , Ulaganathan Mabalirajan , Nahid Ali , Arun Bandopadhyay , Aditya Konar , Jayashree Bagchi Chakraborty , Indrani Chowdhury Mukherjee , Jaydeep Chaudhuri , Sanjit Kumar Mahato , Anirban Manna , Roma Sinha , Prayot Bhattacharya , Jayaraman Vinayagam , Deba Prasad Jana , Sushovan Chowdhury
IPC分类号： C07C39/19 , C07C251/40 , C07D317/50 , C07C255/36 , C07C69/732 , C07C69/017 , C07C251/66
CPC分类号： C07C39/19 , A61K31/05 , A61K31/15 , A61K31/215 , A61K31/277 , A61K31/36 , C07C69/017 , C07C69/732 , C07C251/40 , C07C251/66 , C07C255/36 , C07D317/50
摘要： The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation.
摘要翻译：本发明涉及通过抑制IL-4或IL-5途径抑制来治疗支气管哮喘的通式1的化合物。本发明还涉及通式1化合物通过抑制IL-4或IL-5途径治疗支气管的用途。本发明还涉及通过口服，鼻内，途径或通过吸入需要的哺乳动物施用化合物或所述组合物来抑制IL-4或IL-5途径来治疗哮喘的方法。通式1的化合物可用于减少血管周围和支气管炎。

7. 发明授权

US08519154B2 Method for treatment of bronchial asthma 有权
标题翻译：治疗支气管哮喘的方法
公开(公告)号：US08519154B2
公开(公告)日：2013-08-27
申请号：US13365979
申请日：2012-02-03
申请人： Sibabrata Mukhopadhyay , Mumu Chakraborty , Tulika Mukherjee , Arun Bandyopadhyay , Dipak Kar , Tanima Banerjee , Aditya Konar , Debaprasad Jana , Siddhartha Roy , Santu Bandyopadhyay , Balram Ghosh , Mabalirajan Ulaganathan , Rakesh Kamal Johri , Subhash Chander Sharma , Gurdarshan Singh , Bholanath Paul , Vasanta Madhava Sharma Gangavaram , Jhillu Singh Yadav , Radha Krishna Palakodety
发明人： Sibabrata Mukhopadhyay , Mumu Chakraborty , Tulika Mukherjee , Arun Bandyopadhyay , Dipak Kar , Tanima Banerjee , Aditya Konar , Debaprasad Jana , Siddhartha Roy , Santu Bandyopadhyay , Balram Ghosh , Mabalirajan Ulaganathan , Rakesh Kamal Johri , Subhash Chander Sharma , Gurdarshan Singh , Bholanath Paul , Vasanta Madhava Sharma Gangavaram , Jhillu Singh Yadav , Radha Krishna Palakodety
IPC分类号： C07D209/82 , C07D209/88 , A61K31/403
CPC分类号： C07D209/86 , A61K31/404
摘要： The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthma and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients.Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2═CH3 or CHO; R3═H or OCH3; R4═H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.
摘要翻译：本发明涉及一种治疗支气管哮喘和慢性阻塞性肺疾病（COPD）的方法，其包括向患有哮喘和COPD的患者施用有效剂量的咔唑衍生物或其盐，任选地与药学上可接受的赋形剂。用作磷酸二酯酶-4（PDE-4）酶抑制剂的通式1化合物的结构式，用于治疗哮喘和哮喘相关疾病的信号分子抑制剂如下：其中R1 = H或OCH3; R2 = CH3或CHO; R3 = H或OCH3; R4 = H或OCH3用于从植物Murraya Koenigii的树皮中分离通式1的化合物的草药路线以及用于从碱性化合物如香草醛制备这些化合物的化学途径也被报道。

8. 发明授权

US09302967B2 Substituted cathechols as inhibitors of IL-4 and IL-5 for the treatment of bronchial asthma 有权
标题翻译：取代的导管胆固醇作为IL-4和IL-5的抑制剂用于治疗支气管哮喘
公开(公告)号：US09302967B2
公开(公告)日：2016-04-05
申请号：US14110869
申请日：2012-04-11
申请人： Santu Bandyopadhyay , Balaram Ghosh , Parasuraman Jaisankar , Bikas Chandra Pal , Siddhartha Roy , Bholanath Paul , Arjun Ram , Ulaganathan Mabalirajan , Nahid Ali , Arun Bandopadhyay , Aditya Konar , Jayashree Bagchi Chakraborty , Indrani Choudhury Mukherjee , Jaydeep Chaudhuri , Sanjit Kumar Mahato , Anirban Manna , Roma Sinha , Pradyot Bhattacharya , Jayaraman Vinayagam , Deba Prasad Jana , Sushovan Chowdhury
发明人： Santu Bandyopadhyay , Balaram Ghosh , Parasuraman Jaisankar , Bikas Chandra Pal , Siddhartha Roy , Bholanath Paul , Arjun Ram , Ulaganathan Mabalirajan , Nahid Ali , Arun Bandopadhyay , Aditya Konar , Jayashree Bagchi Chakraborty , Indrani Choudhury Mukherjee , Jaydeep Chaudhuri , Sanjit Kumar Mahato , Anirban Manna , Roma Sinha , Pradyot Bhattacharya , Jayaraman Vinayagam , Deba Prasad Jana , Sushovan Chowdhury
IPC分类号： A61K31/14 , A61K31/05 , C07C39/19 , A61K31/15 , A61K31/215 , A61K31/277 , A61K31/36 , C07C69/017 , C07C69/732 , C07C251/40 , C07C251/66 , C07C255/36 , C07D317/50
CPC分类号： C07C39/19 , A61K31/05 , A61K31/15 , A61K31/215 , A61K31/277 , A61K31/36 , C07C69/017 , C07C69/732 , C07C251/40 , C07C251/66 , C07C255/36 , C07D317/50
摘要： The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation.
摘要翻译：本发明涉及通过抑制IL-4或IL-5途径抑制来治疗支气管哮喘的通式1的化合物。本发明还涉及通式1化合物通过抑制IL-4或IL-5途径治疗支气管的用途。本发明还涉及通过口服，鼻内，途径或通过吸入需要的哺乳动物施用化合物或所述组合物来抑制IL-4或IL-5途径来治疗哮喘的方法。通式1的化合物可用于减少血管周围和支气管炎。

9. 发明授权

US08150994B2 Providing flow control and moderation in a distributed message processing system 有权
标题翻译：在分布式消息处理系统中提供流量控制和审核
公开(公告)号：US08150994B2
公开(公告)日：2012-04-03
申请号：US11144412
申请日：2005-06-03
申请人： Wayne A. Clark , Lee B. Graber , Kartik Paramasivam , Siddhartha Roy , Sanjib Saha , Sumitra Sujanani
发明人： Wayne A. Clark , Lee B. Graber , Kartik Paramasivam , Siddhartha Roy , Sanjib Saha , Sumitra Sujanani
IPC分类号： G06F15/16
CPC分类号： H04L47/22 , G06Q10/06 , H04L47/10 , H04L47/25
摘要： Systems and methods for controlling the work load on a distributed system comprising a plurality of stages are provided. The capacity of a present stage is monitored, using either various resources of the present stage or rates of work completion and work receipt of the present stage. Information indicating the capacity of a succeeding stage are obtained and communicated to the present stage. The monitored capacity information of the present stage and the communicated information of the succeeding stage, either alone or in combination, are used to determine if a throttling action is necessary to control the load of work at the present stage. A provided throttling technique inserts an appropriate delay before the present stage to allow the present stage to process an amount of work without saturating the capacity of the present stage. This technique is applied at each stage of the distributed system to control the work load of the overall system by controlling the work load at each stage.
摘要翻译：提供了用于控制包括多个级的分布式系统上的工作负载的系统和方法。使用现阶段的各种资源或工作完成率和现阶段工作收到情况监测现阶段的能力。获得指示后续能力的信息并传达到现阶段。目前阶段的监控能力信息和后续阶段的通信信息单独或组合用于确定是否需要节流动作来控制现阶段的工作负荷。提供的节流技术在当前阶段之前插入适当的延迟，以允许当前阶段处理一定量的工作而不使本阶段的容量饱和。该技术应用于分布式系统的各个阶段，通过控制各阶段的工作负荷来控制整个系统的工作负荷。

10. 发明申请

US20090233868A1 Small antiviral peptides against hepatitis C virus 审中-公开
标题翻译：针对丙型肝炎病毒的小抗病毒肽
公开(公告)号：US20090233868A1
公开(公告)日：2009-09-17
申请号：US12284728
申请日：2008-09-24
申请人： Saumitra Das , Siddhartha Roy , Upasana Ray , Asit Kumar Manna , Tanmoy Mondal , Romi Gupta , Renuka Pudi , Sudhamani Sonny
发明人： Saumitra Das , Siddhartha Roy , Upasana Ray , Asit Kumar Manna , Tanmoy Mondal , Romi Gupta , Renuka Pudi , Sudhamani Sonny
IPC分类号： A61K38/16 , C07K14/00 , C07K7/00 , C12N15/11 , C12N15/00 , A61K38/10 , A61K38/08 , A61K31/7088
CPC分类号： C07K14/4713 , A61K31/7088 , A61K38/00
摘要： Disclosed herein is a small 7 amino-acid peptide, corresponding to the C terminus of RRM2 of the human La protein that binds to the IRES element of hepatitis C virus RNA and its derivatives. This disclosure demonstrates that this 7-mer interacts with the HCV IRES element both in vitro and in vivo and can compete against cellular La protein in binding to the HCV RNA. It is also shown here that this 7-mer peptide is able to inhibit HCV-IRES mediated translation in vivo which, in turn, leads to decreased viral replication.
摘要翻译：本文公开了一种小的7个氨基酸的肽，其对应于人类La蛋白的RRM2的C末端，其结合丙型肝炎病毒RNA及其衍生物的IRES元件。该公开内容表明，该7-聚体在体外和体内与HCV IRES元件相互作用，并且可以与结合HCV RNA的细胞La蛋白竞争。这里还显示，这种7聚体肽能够在体内抑制HCV-IRES介导的翻译，这又导致病毒复制的减少。

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