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    • 7. 发明申请
    • IMAGE REGISTRATION SYSTEM WITH NON-RIGID REGISTRATION AND METHOD OF OPERATION THEREOF
    • 具有非刚性注册的图像注册系统及其操作方法
    • US20160027178A1
    • 2016-01-28
    • US14339352
    • 2014-07-23
    • Sony Corporation
    • Liangyin YuMing-Chang Liu
    • G06T7/00A61B6/03A61B6/00A61B5/055
    • A61B5/055A61B6/032A61B6/037A61B6/463A61B6/5235A61B6/5247G06T7/0012G06T7/33G06T2200/04G06T2207/10072G06T2207/30004G06T2207/30016G06T2219/2004
    • An image registration system, and a method of operation of an image registration system thereof, including: an imaging unit for obtaining a pre-operation non-invasive imaging volume and for obtaining an intra-operation non-invasive imaging volume; and a processing unit including: a rigid registration module for generating a rigid registered volume based on the pre-operation non-invasive imaging volume, a region of interest module for isolating a region of interest from the intra-operation non-invasive imaging volume, a point generation module, coupled to the region of interest module, for determining feature points of the region of interest, an optimization module, coupled to the point generation module, for matching the feature points with corresponding points of the rigid registered volume for generating a matched point cloud, and an interpolation module, coupled to the optimization module, for generating a non-rigid registered volume based on the matched point cloud for display on a display interface.
    • 一种图像配准系统及其图像配准系统的操作方法,包括:用于获得术前非侵入性成像体积并用于获得手术中的非侵入性成像体积的成像单元; 以及处理单元,其包括:刚性配准模块,用于基于所述预先操作的非侵入性成像体积产生刚性登记体积;感兴趣区域模块,用于将所述感兴趣区域与所述手术中的非侵入性成像体积隔离; 耦合到感兴趣区域模块的点生成模块,用于确定感兴趣区域的特征点,耦合到点生成模块的优化模块,用于使特征点与刚性登记体积的对应点匹配,以产生 匹配点云,以及耦合到优化模块的插值模块,用于基于匹配点云生成非刚性注册卷,以在显示界面上显示。
    • 10. 发明授权
    • Method and apparatus for automatic HER2 scoring of tissue samples
    • 用于组织样本自动HER2评分的方法和装置
    • US09014444B2
    • 2015-04-21
    • US13659408
    • 2012-10-24
    • Sony Corporation
    • Ming-Chang LiuXimin Zhang
    • G06K9/00G06K9/32G06T7/00
    • G06K9/0014G06T7/0012G06T2207/30024
    • Certain aspects of an apparatus and method for method and apparatus for automatic HER2 scoring of tissue samples may include for determining a cancer diagnosis score comprising identifying one or more nuclei in a slide image of a tissue sample, determine one or more membrane strengths in the slide image surrounding each of the one or more nuclei, classifying one or more cells, each corresponding to the one or more nuclei, in a class among a plurality of classes according to the one or more membrane strengths and determining a cancer diagnosis score based on a percentage of cells classified in each of the plurality of classes.
    • 用于组织样本的自动HER2评分的方法和装置的装置和方法的装置和方法的某些方面可以包括用于确定癌症诊断评分,包括识别组织样本的载玻片中的一个或多个核,确定载玻片中的一个或多个膜强度 围绕所述一个或多个核中的每一个的图像,根据所述一个或多个膜强度在多个类别中的类别中分类每个对应于所述一个或多个细胞核的一个或多个细胞,并且基于 分类为多个类别中的每一个的细胞的百分比。