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    • 4. 发明授权
    • Air ducts formed in automotive structural members
    • 在汽车结构件中形成的空气管道
    • US08641134B2
    • 2014-02-04
    • US13437423
    • 2012-04-02
    • Robert S. SawyerMukesh KumarMartha E. Nefcy
    • Robert S. SawyerMukesh KumarMartha E. Nefcy
    • B60H1/24
    • B60H1/00564B60H1/245B60H1/246
    • An air duct for an automotive vehicle is blow molded with an elongated, hollow structural member to be used as a portion of a body of the vehicle. The structural member has an inner wall defining an elongated cavity communicating with first and second access holes at respective longitudinal positions along the structural member. A parison comprised of a thermally insulating material is inserted into the internal cavity. A source of inflation gas is connected to a mouth portion or the parison. The parison is heated and inflated within the internal cavity to an expanded shape to form the air duct disposed against the inner wall and spanning the first and second access holes. The air duct at one of the access holes is configured as an air inlet. The air duct at the other one of the access holes is configured as an air outlet.
    • 用于机动车辆的空气管道是吹塑成型的,具有细长的中空结构件,用作车身的一部分。 结构构件具有限定在沿着结构构件的各个纵向位置处与第一和第二进入孔连通的细长腔的内壁。 将由隔热材料构成的型坯插入内部空腔。 膨胀气体源连接到口部或型坯。 型坯在内腔内被加热膨胀成扩张形状,以形成靠在内壁上并横跨第一和第二进入孔的空气通道。 一个进入孔的空气管道被构造为空气入口。 在另一个进入孔的空气管道被配置为空气出口。
    • 5. 发明申请
    • Air Ducts Formed in Automotive Structural Members
    • 空气管道组成汽车结构件
    • US20130257106A1
    • 2013-10-03
    • US13437423
    • 2012-04-02
    • Robert S. SawyerMukesh KumarMartha E. Nefcy
    • Robert S. SawyerMukesh KumarMartha E. Nefcy
    • B60H1/26B29C49/22
    • B60H1/00564B60H1/245B60H1/246
    • An air duct for an automotive vehicle is blow molded with an elongated, hollow structural member to be used as a portion of a body of the vehicle. The structural member has an inner wall defining an elongated cavity communicating with first and second access holes at respective longitudinal positions along the structural member. A parison comprised of a thermally insulating material is inserted into the internal cavity. A source of inflation gas is connected to a mouth portion or the parison. The parison is heated and inflated within the internal cavity to an expanded shape to form the air duct disposed against the inner wall and spanning the first and second access holes. The air duct at one of the access holes is configured as an air inlet. The air duct at the other one of the access holes is configured as an air outlet.
    • 用于机动车辆的空气管道是吹塑成型的,具有细长的中空结构件,用作车身的一部分。 结构构件具有限定在沿着结构构件的各个纵向位置处与第一和第二进入孔连通的细长腔的内壁。 将由隔热材料构成的型坯插入内部空腔。 膨胀气体源连接到口部或型坯。 型坯在内腔内被加热膨胀成扩张形状,以形成靠在内壁上并横跨第一和第二进入孔的空气通道。 一个进入孔的空气管道被构造为空气入口。 在另一个进入孔的空气管道被配置为空气出口。
    • 8. 发明申请
    • COMPOSITIONS COMPRISING ANTI-ICAM-1 ANTIBODIES
    • 包含抗ICAM-1抗体的组合物
    • US20110052601A1
    • 2011-03-03
    • US12390246
    • 2009-02-20
    • Shyam S. MohapatraAruna BeheraHiroto MatsuseMukesh Kumar
    • Shyam S. MohapatraAruna BeheraHiroto MatsuseMukesh Kumar
    • A61K39/42A61P11/00A61P31/12
    • C12N15/1138C12N15/111C12N2310/11C12N2320/32
    • There is provided a method of preventing a respiratory infection by administering an effective amount of an agent for regulating ICAM-1 expression. Also provided is a composition for the prevention of respiratory infection including an agent which regulates ICAM expression. method of preventing RSV infection by administering an effective amount of an agent that interferes with the binding of RSV to ICAM-1. A method of preventing RSV infection by administering an effective amount of an agent that down regulates the expression of ICAM-1, thereby decreasing RSV binding to ICAM-1 is also provided. There is provided a method of treating RSV infection by administering an effective amount of an agent for down regulating ICAM-1 expression. A method of blocking RSV-ICAM-1 interaction by administering an effective amount of agents for blocking ICAM sites of binding is provided. Also provided is a compound for blocking RSV-ICAM-1 interaction including an agent for blocking ICAM sites of binding.
    • 提供了一种通过施用有效量的用于调节ICAM-1表达的试剂来预防呼吸道感染的方法。 还提供了用于预防呼吸道感染的组合物,包括调节ICAM表达的药剂。 通过施用有效量的妨碍RSV与ICAM-1的结合的试剂来预防RSV感染的方法。 还提供了通过施用有效量的下调ICAM-1的表达的试剂,从而降低RSV与ICAM-1的结合来预防RSV感染的方法。 提供了通过施用有效量的用于下调ICAM-1表达的试剂来治疗RSV感染的方法。 提供了通过施用有效量的阻断ICAM结合位点的试剂阻断RSV-ICAM-1相互作用的方法。 还提供了用于阻断RSV-ICAM-1相互作用的化合物,其包括用于阻断结合的ICAM位点的试剂。