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1. 发明申请

US20090208206A1 SYSTEMS AND METHODS FOR PRIVATE NETWORK-TO-NETWORK INTERFACE OUT-OF-BAND SIGNALING AND PATH BLOCKING 有权
标题翻译：用于私有网络到网络接口的带外信号和路径阻塞的系统和方法
公开(公告)号：US20090208206A1
公开(公告)日：2009-08-20
申请号：US12032773
申请日：2008-02-18
申请人： Vagish Madrahalli , Nilesh Patil , Hongxing Meng
发明人： Vagish Madrahalli , Nilesh Patil , Hongxing Meng
IPC分类号： H04J14/00 , H04B10/20
CPC分类号： H04L45/026 , H04L45/02
摘要： The present invention provides systems and methods to mix In-Band (IB) and Out-of-Band (OOB) signaling mechanisms under the Private Network-to-Network (PNNI) protocol for optical control plane connectivity. The present invention provides mechanisms for establishing and controlling OOB control plane communications. By default, the mechanisms treat all links as IB to discover nodes and links using IB mechanisms. For any blocked links, the link can be configured as OOB if there is a data communication network (DCN) connection to the remote node
摘要翻译：本发明提供了在专用网络到网络（PNNI）协议下混合带内（IB）和带外（OOB）信令机制的系统和方法，用于光学控制平面连接。本发明提供了用于建立和控制OOB控制平面通信的机制。默认情况下，机制将所有链路视为IB，以使用IB机制发现节点和链路。对于任何阻塞的链接，如果存在与远程节点的数据通信网络（DCN）连接，则链接可以配置为OOB

2. 发明授权

US08045551B2 Systems and methods for private network-to-network interface out-of-band signaling and path blocking 有权
标题翻译：私有网络到网络接口带外信令和路径阻塞的系统和方法
公开(公告)号：US08045551B2
公开(公告)日：2011-10-25
申请号：US12032773
申请日：2008-02-18
申请人： Vagish Madrahalli , Nilesh Patil , Hongxing Meng
发明人： Vagish Madrahalli , Nilesh Patil , Hongxing Meng
IPC分类号： H04L12/28 , H04L12/56 , H04J14/00
CPC分类号： H04L45/026 , H04L45/02
摘要： The present invention provides systems and methods to mix In-Band (IB) and Out-of-Band (OOB) signaling mechanisms under the Private Network-to-Network (PNNI) protocol for optical control plane connectivity. The present invention provides mechanisms for establishing and controlling OOB control plane communications. By default, the mechanisms treat all links as IB to discover nodes and links using IB mechanisms. For any blocked links, the link can be configured as OOB if there is a data communication network (DCN) connection to the remote node.
摘要翻译：本发明提供了在专用网络到网络（PNNI）协议下混合带内（IB）和带外（OOB）信令机制的系统和方法，用于光学控制平面连接。本发明提供了用于建立和控制OOB控制平面通信的机制。默认情况下，机制将所有链路视为IB，以使用IB机制发现节点和链路。对于任何阻塞的链接，如果存在与远程节点的数据通信网络（DCN）连接，则链接可以配置为OOB。

3. 发明授权

US07897724B2 Solid phase Fmoc chemistry process to prepare peptides 失效
标题翻译：固相Fmoc化学过程制备肽
公开(公告)号：US07897724B2
公开(公告)日：2011-03-01
申请号：US11729047
申请日：2007-03-27
申请人： Divya Lal Saksena , Shrikant Mishra , Chandrakesan Muralidharan , Nilesh Patil , Nikhil Umesh Mohe , Mandar Ravindra Maduskar
发明人： Divya Lal Saksena , Shrikant Mishra , Chandrakesan Muralidharan , Nilesh Patil , Nikhil Umesh Mohe , Mandar Ravindra Maduskar
IPC分类号： C07K1/06
CPC分类号： C07K14/75 , C07K14/78 , Y02P20/582
摘要： The present invention relates to an improved process for the preparation of N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1→6)-disulfide of formula (1), which involves assembling a peptide chain comprising of six amino acids and a thioalkyl carboxylic acid in a required sequence on a solid support to obtain a peptide bound resin of formula (2), capping the free amino groups after each coupling, cleaving Dde group in the peptide of formula (2) from the solid support to obtain peptide-solid support of formula (3), guanylating the peptide of formula (3) at ε-lysine-NH2 in an organic solvent to obtain peptide-solid support of formula (4), cleaving and deprotecting all groups in the peptide of formula (4) from the solid support to obtain peptide-amide formula (5), oxidizing the SH-peptide of formula (5) with an appropriate oxidizing agent to obtain the crude peptide-amide of formula (1) and purifying the crude peptide-amide of formula (1) by chromatographic technique. The solid support is either resin or a cellulose support like cotton, gauze, fabric, paper and perloza beads. The described process is simple, easy, environment friendly, takes lesser time and more cost effective.
摘要翻译：本发明涉及一种制备N6-（氨基亚氨基甲基）-N2-（3-巯基-1-氧代丙基）-L-赖氨酰甘氨酰-L-α-天冬氨酰-L-色氨酰-L-脯氨酰基-L- 半胱氨酰胺，式（1）的环状（1→6） - 二硫化物，其包括在固体支持物上以所需的顺序将包含六个氨基酸的肽链和硫代烷基羧酸组装以获得式（2）的肽结合树脂），在每次偶联后封端游离氨基，从固体支持物切割式（2）的肽中的Dde基团以获得式（3）的肽 - 固体支持物，在式（3）的肽上进行脒化，赖氨酸-NH 2在有机溶剂中得到式（4）的肽固体支持物，从固体支持物中切割和脱保护基团中所有基团的肽，得到肽 - 酰胺式（5），氧化SH- 式（5）的肽与适当的氧化剂反应，得到式（1）的粗肽 - 酰胺并纯化粗蛋白 e通过色谱技术制备式（1）的肽 - 酰胺。固体支持物是树脂或纤维素载体，如棉，纱布，织物，纸和perloza珠。描述的过程简单，容易，环保，花费更少的时间和更具成本效益。

4. 发明申请

US20070249806A1 Solid phase Fmoc chemistry process to prepare peptides 失效
标题翻译：固相Fmoc化学过程制备肽
公开(公告)号：US20070249806A1
公开(公告)日：2007-10-25
申请号：US11729047
申请日：2007-03-27
申请人： Divya Saksena , Shrikant Mishra , Chandrakesan Muralidharan , Nilesh Patil , Nikhil Mohe , Mandar Maduskar
发明人： Divya Saksena , Shrikant Mishra , Chandrakesan Muralidharan , Nilesh Patil , Nikhil Mohe , Mandar Maduskar
IPC分类号： C07K7/60 , C07K7/06
CPC分类号： C07K14/75 , C07K14/78 , Y02P20/582
摘要： The present invention relates to an improved process for the preparation of N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(16)-disulfide of formula (1), which involves assembling a peptide chain comprising of six amino acids and a thioalkyl carboxylic acid in a required sequence on a solid support to obtain a peptide bound resin of formula (2), capping the free amino groups after each coupling, cleaving Dde group in the peptide of formula (2) from the solid support to obtain peptide-solid support of formula (3), guanylating the peptide of formula (3) at ε-lysine-NH2 in an organic solvent to obtain peptide-solid support of formula (4), cleaving and deprotecting all groups in the peptide of formula (4) from the solid support to obtain peptide-amide formula (5), oxidizing the SH-peptide of formula (5) with an appropriate oxidizing agent to obtain the crude peptide-amide of formula (1) and purifying the crude peptide-amide of formula (1) by chromatographic technique. The solid support is either resin or a cellulose support like cotton, gauze, fabric, paper and perloza beads. The described process is simple, easy, environment friendly, takes lesser time and more cost effective
摘要翻译：本发明涉及一种制备N 6 - （氨基亚氨基甲基）-N 2 - （3-巯基-1-氧代丙基）-L-赖氨酰甘氨酰基 - L-α-天冬氨酰基-L-色氨酰-L-脯氨酰基-L-半胱氨酰胺，式（1）的环状（16） - 二硫化物，其包括以所需顺序组装包含六个氨基酸的肽链和硫代烷基羧酸在固体支持物上获得式（2）的肽结合树脂，每次偶联后封端游离氨基，从固体支持物切割式（2）的肽中的Dde基团以获得式（3）的肽 - 固体支持物），在有机溶剂中在ε-赖氨酸-NH 2上对式（3）的肽进行脒化，得到式（4）的肽固体支持物，将式（4）的肽中的所有基团切割和脱保护（4）从固体支持物得到肽 - 酰胺配方（5），用合适的氧化剂氧化式（5）的SH-肽，得到粗肽 - 酰胺通过色谱技术纯化式（1）的粗肽酰胺。固体支持物是树脂或纤维素载体，如棉，纱布，织物，纸和perloza珠。描述的过程简单，容易，环保，花费更少的时间和更具成本效益

5. 发明申请

US20050113586A1 Biphasic process for epoxidation of olefinic compound using chromate or dichromate catalyst 失效
标题翻译：使用铬酸盐或重铬酸盐催化剂对烯烃化合物进行环氧化的双相过程
公开(公告)号：US20050113586A1
公开(公告)日：2005-05-26
申请号：US10721796
申请日：2003-11-26
申请人： Vasant Choudhary , Nilesh Patil
发明人： Vasant Choudhary , Nilesh Patil
IPC分类号： C07D301/19
CPC分类号： C07D301/19
摘要： The present invention relates to a biphasic process for the epoxidation of an organic compound by organic compound by organic hydroperoxide. More particularly, the present invention relates to a biphasic process for the epoxidation of an organic compound by organic hydroperoxide to the corresponding epoxide, using chromate or dichromate anions as the catalyst in aqueous medium.
摘要翻译：本发明涉及通过有机氢过氧化物对有机化合物进行环氧化的双相方法。更具体地说，本发明涉及通过有机氢过氧化物将有机化合物环氧化成相应的环氧化物的双相方法，其中使用铬酸盐或重铬酸盐阴离子作为水介质中的催化剂。

6. 发明申请

US20050065355A1 Process for epoxidation of a liquid olefinic organic compound using a supported nano-gold catalyst 失效
标题翻译：使用负载型纳米金催化剂对液态烯属有机化合物进行环氧化的方法
公开(公告)号：US20050065355A1
公开(公告)日：2005-03-24
申请号：US10665356
申请日：2003-09-22
申请人： Vasant Choudhary , Nilesh Patil , Balu Uphade , Prabhas Jana
发明人： Vasant Choudhary , Nilesh Patil , Balu Uphade , Prabhas Jana
IPC分类号： C07D301/12 , C07D301/19
CPC分类号： C07D301/19
摘要： The present invention relates to a process for the liquid phase epoxidation of a normally liquid olefinic compound to corresponding organic epoxide compound using aqueous or anhydrous organic hydroperoxide as an oxidizing agent in the presence of a supported nano-gold catalysts at the effective organic hydroperoxide/olefinic compound mole ratio, catalyst/olefinic compound weight ratio and temperature to yield the epoxide.
摘要翻译：本发明涉及在负载的纳米金催化剂存在下，在有效的有机氢过氧化物/烯属物上使用水或无机有机氢过氧化物作为氧化剂，将正常液体的烯属化合物液相环氧化成相应的有机环氧化合物的方法化合物摩尔比，催化剂/烯烃化合物的重量比和温度，得到环氧化物。

7. 发明申请

US20080182781A1 Process for the Preparation of Peptides 审中-公开
标题翻译：肽的制备方法
公开(公告)号：US20080182781A1
公开(公告)日：2008-07-31
申请号：US10592118
申请日：2004-10-10
申请人： Divya Saksena , Shrikant Mishra , Chandrakesan Muralidharan , Milind Thakare , Nilesh Patil , Aruna Khare
发明人： Divya Saksena , Shrikant Mishra , Chandrakesan Muralidharan , Milind Thakare , Nilesh Patil , Aruna Khare
IPC分类号： A61K38/12 , C07K7/64 , C07K7/06
CPC分类号： C07K7/06 , Y02P20/55
摘要： The present invention relates to an improved process for the preparation of N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1→6)-disulfide of formula (1), which involves assembling amino acid residues and a thioalkyl carboxylic acid with appropriate protecting groups on a solid phase resin, cleaving the peptide thus obtained from the resin with concomitant removal of side chain protecting groups except Acm protecting group of thiol moiety to obtain peptide amide of formula (3), converting lysine residue of peptide amide of formula (3) having protected thiol group to homoarginine residue by guanylation to obtain peptide of formula (4), preparing silver peptide of formula (5), followed by simultaneous deprotection, obtaining silver peptide of formula (5) and oxidation of silver peptide to obtain crude peptide amide comprising compound of formula (1) and finally subjecting to chromatographic purification. The described process is simple, easy, environment friendly and cost effective.
摘要翻译：本发明涉及一种制备N 6 - （氨基亚氨基甲基）-N 2 - （3-巯基-1-氧代丙基-L-赖氨酰甘氨酰-L- -α-天冬氨酰基-L-色氨酰-L-脯氨酰基-L-半胱氨酰胺，式（1）的环状（1-> 6） - 二硫化物，其包括将氨基酸残基和硫代烷基羧酸与固体上适当的保护基团组装通过除去除巯基部分的Acm保护基之外的侧链保护基除去由树脂得到的肽，从而得到式（3）的肽酰胺，转化具有被保护的硫醇的式（3）的肽酰胺的赖氨酸残基通过胍基化得到高精氨酸残基，得到式（4）的肽，制备式（5）的银肽，然后同时去保护，得到式（5）的银肽和银肽的氧化，得到粗肽酰胺，式（1），最后进行色谱 c净化。描述的过程简单，容易，环保，成本效益高。

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