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1. 发明授权

US07945022B2 Radiation therapy plan dose perturbation system and method 有权
标题翻译：辐射治疗计划剂量扰动系统及方法
公开(公告)号：US07945022B2
公开(公告)日：2011-05-17
申请号：US12402785
申请日：2009-03-12
申请人： Benjamin E. Nelms , William E. Simon
发明人： Benjamin E. Nelms , William E. Simon
IPC分类号： A61N5/10
CPC分类号： A61N5/1071 , A61N5/1038 , A61N2005/1034 , A61N2005/1076
摘要： A method of determining a patient dose during or prior to therapy from an external radiation beam includes determining a dose distribution from a patient plan as delivered in a QA phantom at each appropriate beam angle and comparing the dose distribution determined from measurements or calculations to a corresponding treatment planning system (TPS) dose modeled distribution in the QA phantom and providing a correction distribution when applied to the TPS dose modeled distribution results in the dose distribution determined. The correction distribution may optionally be interpolated to non-measured points for each beam angle and geometrically projected toward the source of radiation through a volume that equals a dose volume of the TPS for a patient beam for each beam angle. The correction distribution is applied to the TPS patient dose volume for each beam angle for providing a corrected dose distribution in the patient.
摘要翻译：从外部辐射束确定治疗期间或之前的患者剂量的方法包括确定在每个适当的束角度下以质量检验模型传递的患者计划的剂量分布，并将从测量或计算确定的剂量分布与相应的治疗计划系统（TPS）剂量建模分布在QA体模中，并在应用于TPS剂量建模分布结果时提供校正分布，确定剂量分布。校正分布可以可选地内插到每个波束角的非测量点，并且通过相当于用于每个波束角度的患者波束的TPS的剂量体积的体积朝向辐射源几何投影。校正分布被应用于每个波束角的TPS患者剂量体积，以在患者体内提供校正的剂量分布。

2. 发明申请

US20110022360A1 MULTIPLE AXES SCANNING SYSTEM AND METHOD FOR MEASURING RADIATION FROM A RADIATION SOURCE 有权
标题翻译：用于测量辐射源辐射的多个轴扫描系统和方法
公开(公告)号：US20110022360A1
公开(公告)日：2011-01-27
申请号：US12840331
申请日：2010-07-21
申请人： William E. Simon , Mark Rose , Ronald J. Watts , Seth Brechbill , William Austhof , Thomas Allan Simon , Jakub Kozelka
发明人： William E. Simon , Mark Rose , Ronald J. Watts , Seth Brechbill , William Austhof , Thomas Allan Simon , Jakub Kozelka
IPC分类号： G06F15/00 , G01T1/00
CPC分类号： A61N5/1048 , A61N5/10 , A61N5/1075 , A61N5/1082 , A61N2005/1076
摘要： A three dimensional radiation measurement scanning system includes a circular drive operable with horizontal and vertical drives for moving a radiation detector through first, second and third orthogonal axes in a three dimensional scanning of the detector in a water tank. Motor are coupled to the drives and activated by a controller for providing the movement of the radiation detector which providing radiation field sensing signals for locations of the detector throughout the tank. A reference detector is fixed for comparing its radiation field measurements with those of the scanned radiation detector. An offset mount carries the radiation detector allowing it to be extended beyond the circular ring gear during horizontal movement of the radiation detector and thus position the radiation detector at wall surfaces of the water tank.
摘要翻译：三维辐射测量扫描系统包括圆形驱动器，其可操作于水平和垂直驱动器，用于在水箱中的检测器的三维扫描中通过第一，第二和第三正交轴移动辐射检测器。电动机耦合到驱动器并由控制器激活，以提供放射线检测器的运动，该辐射检测器为检测器在整个罐中的位置提供辐射场感测信号。参考检测器是固定的，用于将其辐射场测量与扫描的辐射探测器的辐射场测量值进行比较。偏移安装座承载放射线检测器，允许其在辐射检测器的水平移动期间延伸超过圆形环形齿轮，并且因此将辐射检测器定位在水箱的壁表面。

3. 发明申请

US20090252292A1 RADIATION THERAPY PLAN DOSE PERTURBATION SYSTEM AND METHOD 有权
标题翻译：辐射治疗计划剂量刺激系统及方法
公开(公告)号：US20090252292A1
公开(公告)日：2009-10-08
申请号：US12402785
申请日：2009-03-12
申请人： William E. Simon , Benjamin E. Nelms
发明人： William E. Simon , Benjamin E. Nelms
IPC分类号： A61N5/10 , H05G1/42 , G01T1/02
CPC分类号： A61N5/1071 , A61N5/1038 , A61N2005/1034 , A61N2005/1076
摘要： A method of determining a patient dose during or prior to therapy from an external radiation beam includes determining a dose distribution from a patient plan as delivered in a QA phantom at each appropriate beam angle and comparing the dose distribution determined from measurements or calculations to a corresponding treatment planning system (TPS) dose modeled distribution in the QA phantom and providing a correction distribution when applied to the TPS dose modeled distribution results in the dose distribution determined. The correction distribution may optionally be interpolated to non-measured points for each beam angle and geometrically projected toward the source of radiation through a volume that equals a dose volume of the TPS for a patient beam for each beam angle. The correction distribution is applied to the TPS patient dose volume for each beam angle for providing a corrected dose distribution in the patient.
摘要翻译：从外部辐射束确定治疗期间或之前的患者剂量的方法包括确定在每个适当的束角度下以质量检验模型传递的患者计划的剂量分布，并将从测量或计算确定的剂量分布与相应的治疗计划系统（TPS）剂量建模分布在QA体模中，并在应用于TPS剂量建模分布结果时提供校正分布，确定剂量分布。校正分布可以可选地内插到每个波束角的非测量点，并且通过相当于用于每个波束角度的患者波束的TPS的剂量体积的体积朝向辐射源几何投影。校正分布被应用于每个波束角的TPS患者剂量体积，以在患者体内提供校正的剂量分布。

4. 发明授权

US08044359B2 Three dimensional dosimetry using solid array geometry 有权
标题翻译：使用固体阵列几何的三维剂量测定
公开(公告)号：US08044359B2
公开(公告)日：2011-10-25
申请号：US12401949
申请日：2009-03-11
申请人： William E. Simon
发明人： William E. Simon
IPC分类号： G01T1/02
CPC分类号： A61N5/1071 , A61N5/1038 , A61N2005/1034 , A61N2005/1076
摘要： A dosimeter comprising an ionizing radiation detector array is used to generally encompass a three dimensional geometric shape such as that employed as a phantom in radiation dosimetry measurements. The ionizing radiation detector array may include passive or active detectors. The active detectors in the array may comprise diodes, ionization chambers, luminescent sensors or amorphous silicon. The three dimensional geometric shape may comprise a shape defined by a closed directrix, wherein each of a plurality of detectors within the ionizing detector array is within an envelope defined by a generatrix of the directrix. The closed directrix may be an open or closed cylinder, or a structure having a cross section described by a polygon. The plurality of detectors may only be positioned on or at least proximate the envelope.
摘要翻译：包括电离辐射检测器阵列的剂量计用于通常包含三维几何形状，例如在辐射剂量测量中用作幻影的形状。电离辐射检测器阵列可以包括无源或有源检测器。阵列中的有源检测器可以包括二极管，电离室，发光传感器或非晶硅。三维几何形状可以包括由封闭的线阵定义的形状，其中电离检测器阵列内的多个检测器中的每一个在由该阵列的母线限定的包络内。封闭的准线可以是开放的或封闭的圆柱体，或具有由多边形描述的横截面的结构。多个检测器可以仅位于信封上或至少靠近信封。

5. 发明授权

US4871914A Low-cost radon detector 失效
标题翻译：低成本氡探测器
公开(公告)号：US4871914A
公开(公告)日：1989-10-03
申请号：US46933
申请日：1987-05-05
申请人： William E. Simon , Thomas L. Powers , Glenn W. Ernsberger
发明人： William E. Simon , Thomas L. Powers , Glenn W. Ernsberger
IPC分类号： G01T1/167 , G01T1/17 , G01T1/178 , G01T1/24
CPC分类号： G01T1/178 , G01T1/247 , Y10S250/02
摘要： A low-cost radon detector using a solid state diode having a depletion layer disposed close enough to a test medium that alpha particles deposit their energy in the depletion layer. The signal produced by the diode is amplified and pulses are discriminated for levels over a threshold typical of pulse levels produced by radioactive decay of radon daughters on the surface of the sensor. More than one amplifier and threshold detector are provided, and the sensor can have plural solid state diodes. Pulses occurring exclusively on one channel are counted and pulses occurring in coincidence on more than one channel are ignored as instances of transient disturbance. A conductive enclosure around the sensor element can be biased to force radon daughter ions to plate out the sensor, whereupon decay of the daughters produces pulses falling closely into pulse height ranges well above the noise threshold. Pulse counts and time lapse are monitored both long term and short term.
摘要翻译：一种低成本氡检测器，其使用具有耗尽层的固态二极管，该耗尽层与测试介质足够靠近，α粒子将其能量沉积在耗尽层中。由二极管产生的信号被放大，并且脉冲被鉴别在传感器表面上由氡气的放射性衰变产生的脉冲水平典型值的阈值之上。提供了多个放大器和阈值检测器，并且传感器可以具有多个固态二极管。在一个通道上专门出现的脉冲被计数，并且在多个通道上以一致的脉冲被忽略，因为瞬时干扰的情况。传感器元件周围的导电外壳可被偏置以迫使氡子离子平衡传感器，于是女儿的衰减产生的脉冲紧密地落入远高于噪声阈值的脉冲高度范围内。长期和短期监测脉搏计数和时间流逝。

6. 发明授权

US4442496A Radiation energy measurement apparatus 失效
标题翻译：辐射能量测量仪器
公开(公告)号：US4442496A
公开(公告)日：1984-04-10
申请号：US446501
申请日：1982-12-03
申请人： William E. Simon , Richard D. Richards
发明人： William E. Simon , Richard D. Richards
IPC分类号： G01T1/36 , H05G1/26 , G01D18/00
CPC分类号： G01T1/36 , H05G1/26 , H05G1/265
摘要： A radiation analysis instrument is described for measuring the characteristics of radiation emanating from a source (XS). The instrument includes two absorbers (a, b) and corresponding detectors (10, 12) with the detectors being disposed in the path of the radiation and the absorbers being interposed between the corresponding detector and the source. A circuit (16) digitizes the analog signals derived by the two detectors and provides the digital values to a microcomputer (18) which stores these digitals values within a memory (50). A microprocessor (48) processes the digital signals stored within the memory (50) to analyze characteristics of the radiation emitted from and the potential applied across the source (XS). This instrument is particularly useful in measuring the kVp applied to X-ray tubes.
摘要翻译：描述了辐射分析仪器，用于测量从源（XS）发出的辐射特性。仪器包括两个吸收器（a，b）和相应的检测器（10,12），其中检测器设置在辐射的路径中，并且吸收器插入在相应的检测器和源之间。电路（16）将由两个检测器导出的模拟信号数字化，并将数字值提供给将这些数字值存储在存储器（50）内的微计算机（18）。微处理器（48）处理存储在存储器（50）内的数字信号，以分析从源（XS）上施加的辐射和施加的电位的特性。该仪器特别适用于测量应用于X射线管的kVp。

7. 发明授权

US08321179B2 Multiple axes scanning system and method for measuring radiation from a radiation source 有权
标题翻译：用于测量辐射源辐射的多轴扫描系统和方法
公开(公告)号：US08321179B2
公开(公告)日：2012-11-27
申请号：US12840331
申请日：2010-07-21
申请人： William E. Simon , Mark Rose , Ronald J. Watts , Seth Brechbill , William Austhof , Thomas Allan Simon , Jakub Kozelka
发明人： William E. Simon , Mark Rose , Ronald J. Watts , Seth Brechbill , William Austhof , Thomas Allan Simon , Jakub Kozelka
IPC分类号： G01T1/00
CPC分类号： A61N5/1048 , A61N5/10 , A61N5/1075 , A61N5/1082 , A61N2005/1076
摘要： A three dimensional radiation measurement scanning system includes a circular drive operable with horizontal and vertical drives for moving a radiation detector through first, second and third orthogonal axes in a three dimensional scanning of the detector in a water tank. Motor are coupled to the drives and activated by a controller for providing the movement of the radiation detector which providing radiation field sensing signals for locations of the detector throughout the tank. A reference detector is fixed for comparing its radiation field measurements with those of the scanned radiation detector. An offset mount carries the radiation detector allowing it to be extended beyond the circular ring gear during horizontal movement of the radiation detector and thus position the radiation detector at wall surfaces of the water tank.
摘要翻译：三维辐射测量扫描系统包括圆形驱动器，其可操作于水平和垂直驱动器，用于在水箱中的检测器的三维扫描中通过第一，第二和第三正交轴移动辐射检测器。电动机耦合到驱动器并由控制器激活，以提供放射线检测器的运动，该辐射检测器为检测器在整个罐中的位置提供辐射场感测信号。参考检测器是固定的，用于将其辐射场测量与扫描的辐射探测器的辐射场测量值进行比较。偏移安装座承载放射线检测器，允许其在辐射检测器的水平移动期间延伸超过圆形环形齿轮，并且因此将辐射检测器定位在水箱的壁表面。

8. 发明申请

US20130048883A1 SYSTEMS AND METHODS FOR PREVENTING UNSAFE MEDICAL TREATMENT 审中-公开
标题翻译：用于预防不安全医疗治疗的系统和方法
公开(公告)号：US20130048883A1
公开(公告)日：2013-02-28
申请号：US13601308
申请日：2012-08-31
申请人： William E. Simon , Jeffrey A. Simon , Michael Bealer , Kai Wundke , Jeffrey Michael Kapatoes , Matthew J. Daniels , Sanjeev Saini
发明人： William E. Simon , Jeffrey A. Simon , Michael Bealer , Kai Wundke , Jeffrey Michael Kapatoes , Matthew J. Daniels , Sanjeev Saini
IPC分类号： A61N5/00
CPC分类号： A61N5/1048 , A61N2005/1074 , A61N2005/1094
摘要： A treatment safety device is operable by a computer-based treatment safety module to prevent, by at least one of an operational interlock and a warning indicator, a medical treatment unless the treatment safety module determines that predetermined treatment verification criteria are met. The treatment safety device can tie into an existing operational interlock, such as an electrical door interlock. In a radiation oncology application, the treatment safety module verification criteria can include a satisfactory correspondence between elements of a pending treatment and an intended treatment.
摘要翻译：处理安全装置可由基于计算机的治疗安全模块操作，以通过操作互锁和警告指示器中的至少一个来防止医疗，除非治疗安全模块确定满足预定的治疗验证标准。治疗安全装置可以结合现有的操作互锁，例如电动门互锁。在放射肿瘤学应用中，治疗安全模块验证标准可以包括未决治疗的要素与预期治疗之间令人满意的对应关系。

9. 发明申请

US20090250618A1 THREE DIMENSIONAL DOSIMETRY USING SOLID ARRAY GEOMETRY 有权
标题翻译：使用固体几何几何的三维度量
公开(公告)号：US20090250618A1
公开(公告)日：2009-10-08
申请号：US12401949
申请日：2009-03-11
申请人： William E. Simon
发明人： William E. Simon
IPC分类号： G01T1/02 , G01T1/26
CPC分类号： A61N5/1071 , A61N5/1038 , A61N2005/1034 , A61N2005/1076
摘要： A dosimeter comprising an ionizing radiation detector array is used to generally encompass a three dimensional geometric shape such as that employed as a phantom in radiation dosimetry measurements. The ionizing radiation detector array may include passive or active detectors. The active detectors in the array may comprise diodes, ionization chambers, luminescent sensors or amorphous silicon. The three dimensional geometric shape may comprise a shape defined by a closed directrix, wherein each of a plurality of detectors within the ionizing detector array is within an envelope defined by a generatrix of the directrix. The closed directrix may be an open or closed cylinder, or a structure having a cross section described by a polygon. The plurality of detectors may only be positioned on or at least proximate the envelope.
摘要翻译：包括电离辐射检测器阵列的剂量计用于通常包含三维几何形状，例如在辐射剂量测量中用作幻影的形状。电离辐射检测器阵列可以包括无源或有源检测器。阵列中的有源检测器可以包括二极管，电离室，发光传感器或非晶硅。三维几何形状可以包括由封闭的线阵定义的形状，其中电离检测器阵列内的多个检测器中的每一个在由该阵列的母线限定的包络内。封闭的准线可以是开放的或封闭的圆柱体，或具有由多边形描述的横截面的结构。多个检测器可以仅位于信封上或至少靠近信封。

10. 发明授权

US6125335A Wide field calibration of a multi-sensor array 失效
标题翻译：多传感器阵列的宽场校准
公开(公告)号：US6125335A
公开(公告)日：2000-09-26
申请号：US58639
申请日：1998-04-10
申请人： William E. Simon , Jie Shi , Craig A. Iannello
发明人： William E. Simon , Jie Shi , Craig A. Iannello
IPC分类号： G01T1/29 , H01L21/00
CPC分类号： G01T1/29
摘要： A method has been developed to calibrate the relative radiation response of sensors in an array by substitutional analysis of the sensor outputs caused by a radiation field wider than the array. The array is positioned in the wide field in such a way that the sensor positions in the array are exchanged once by translation in order to calculate ratios of neighboring detector sensitivity and once by rotation in order to calculate ratios of mirror detector sensitivities. There is no dependence on dose reproducibility, field flatness or symmetry. The method requires that the profile shape produced by the machine during each measurement be reproducible and that the array movements do not affect the scattering conditions.
摘要翻译：已经开发了一种通过由比阵列更宽的辐射场引起的传感器输出的替代分析来校准阵列中的传感器的相对辐射响应的方法。该阵列定位在宽场中，使得阵列中的传感器位置通过平移交换一次，以便计算相邻检测器灵敏度的比率，并且通过旋转计算一次以便计算镜检测器灵敏度的比率。不依赖于剂量重现性，场平坦度或对称性。该方法要求在每个测量期间由机器产生的轮廓形状是可重现的，并且阵列运动不影响散射条件。

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