专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20220411442A1 POLYCYCLIC AMINES AS OPIOID RECEPTOR MODULATORS 有权
公开(公告)号：US20220411442A1
公开(公告)日：2022-12-29
申请号：US16885604
申请日：2020-05-28
申请人： XIAODONG WANG , Hua Zhong
发明人： XIAODONG WANG , Hua Zhong
IPC分类号： C07F5/02 , C07D401/04 , C07D205/04 , C07D409/04 , C07D211/14 , C07D417/04 , C07D413/04 , C07D401/14 , C07D207/09 , C07D211/34 , C07D405/04 , C07D417/06 , C07D223/04 , C07D401/12 , C07D223/06 , C07D417/10 , C07D409/14 , C07D409/06 , C07D417/14 , C07D405/14 , C07D451/02 , C07D473/00 , C07D471/08 , C07D513/04 , C07D475/00
摘要： The present invention provides a genus of polycyclic amines that are useful as opioid receptor modulators. The compounds of the invention are useful in both therapeutic and diagnostic methods, including for treating pain, neurological disorders, cardiac disorders, bowel disorders, drug and alcohol addiction, drug overdose, urinary disorders, respiratory disorders, sexual dysfunction, psoriasis, graft rejection or cancer.

2. 发明授权

US10676456B2 Polycyclic amines as opioid receptor modulators 有权
公开(公告)号：US10676456B2
公开(公告)日：2020-06-09
申请号：US15917866
申请日：2018-03-12
申请人： Xiaodong Wang , Hua Zhong
发明人： Xiaodong Wang , Hua Zhong
IPC分类号： C07D401/04 , C07D409/04 , C07D211/34 , C07D417/04 , C07D413/04 , C07D401/14 , C07D205/04 , C07D207/12 , C07D211/42 , C07D405/04 , C07D207/09 , C07D225/02 , C07D401/06 , C07D211/26 , C07D417/10 , C07D413/10 , C07D211/32 , C07D409/08 , C07D401/10 , C07D409/06 , C07D405/14 , C07D417/14 , C07D403/06 , C07D413/14 , C07D471/08 , C07D473/00 , C07D491/056 , C07D513/04 , C07D487/04 , C07F5/04 , C07D211/22 , C07D413/06 , C07D401/12 , C01F5/04 , C07D409/14 , C07F5/02
摘要： The present invention provides a genus of polycyclic amines that are useful as opioid receptor modulators. The compounds of the invention are useful in both therapeutic and diagnostic methods, including for treating pain, neurological disorders, cardiac disorders, bowel disorders, drug and alcohol addiction, drug overdose, urinary disorders, respiratory disorders, sexual dysfunction, psoriasis, graft rejection or cancer.

3. 发明授权

US07882283B2 Virtualization support in a multiprocessor storage area network 有权
标题翻译：多处理器存储区域网络中的虚拟化支持
公开(公告)号：US07882283B2
公开(公告)日：2011-02-01
申请号：US11605843
申请日：2006-11-28
申请人： Maurilio Cometto , Jeevan Kamisetty , Arindam Paul , Hua Zhong , Varagur V. Chandrasekaran
发明人： Maurilio Cometto , Jeevan Kamisetty , Arindam Paul , Hua Zhong , Varagur V. Chandrasekaran
IPC分类号： G06F3/00 , G06F13/12 , G06F13/38 , G06F5/00
CPC分类号： H04L67/1097 , G06F3/0613 , G06F3/0635 , G06F3/067
摘要： Support for virtualization in a storage area networks may be provided using a variety of techniques. In one embodiment of the present invention, exchange level load balancing may be provided by determining if input/outputs (IOs) received by a device are new. If a particular IO is new, the IO may be assigned to a particular data path processor and an context may be created corresponding to the IO and to the processor. Then, when an event corresponding to the IO is received, the event may be forwarded to the processor assigned to the IO.
摘要翻译：可以使用各种技术来提供对存储区域网络中的虚拟化的支持。在本发明的一个实施例中，可以通过确定由设备接收的输入/输出（IO）是否新的来提供交换级负载平衡。如果特定IO是新的，则可以将IO分配给特定的数据路径处理器，并且可以对应于IO和处理器创建上下文。然后，当接收到与IO相对应的事件时，事件可以被转发到分配给IO的处理器。

4. 发明授权

US07576238B2 Process for the preparation of substituted tetralin and substituted indane derivatives 有权
标题翻译：制备取代的四氢化萘和取代的茚满衍生物的方法
公开(公告)号：US07576238B2
公开(公告)日：2009-08-18
申请号：US11958618
申请日：2007-12-18
申请人： Fan Zhang-Plasket , Hua Zhong , Frank Villani
发明人： Fan Zhang-Plasket , Hua Zhong , Frank Villani
IPC分类号： C07C381/00
CPC分类号： C07C323/52 , C07B2200/07 , C07C211/27 , C07C303/08 , C07C319/02 , C07C319/14 , C07C319/20 , C07C319/28 , C07C2602/08 , C07C2602/10 , C07C309/88
摘要： The present invention relates to novel processes for the preparation of substituted tetralin and substituted indane derivatives. The present invention is further directed to novel processes for the preparation of intermediates in the preparation of the substituted tetralin and substituted indane derivatives.
摘要翻译：本发明涉及制备取代的四氢化萘和取代的茚满衍生物的新方法。本发明进一步涉及在制备取代的四氢化萘和取代的二氢化茚衍生物时制备中间体的新方法。

5. 发明授权

US07266478B2 Knitwear modeling 失效
标题翻译：针织造型
公开(公告)号：US07266478B2
公开(公告)日：2007-09-04
申请号：US10850653
申请日：2004-05-21
申请人： Ying-Qing Xu , Baining Guo , Hua Zhong , Heung-Yeung Shum
发明人： Ying-Qing Xu , Baining Guo , Hua Zhong , Heung-Yeung Shum
IPC分类号： G06F17/50
CPC分类号： D04B37/00
摘要： Knitwear modeling is disclosed. A macrostructure corresponding to a three-dimensional object is generated, based on a stitch pattern and optionally a color pattern. Yarn microstructure is generated and applied to the macrostructure to yield a knitwear model. The stitch positions of the macrostructure can be perturbed to achieve stitch position irregularities. The fluffiness of the yarn microstructure can be controlled. In an alternative embodiment, a two-dimensional knitwear texture is generated, which can then be mapped to a three-dimensional object to yield a knitwear model.
摘要翻译：披露了针织品造型。基于针迹图案和可选的颜色图案，生成对应于三维物体的宏观结构。生产纱线微观结构并应用于宏观结构以产生针织品模型。可以扰动宏观结构的缝合位置以达到缝合位置不规则。可以控制纱线微结构的蓬松性。在替代实施例中，生成二维针织品纹理，然后将其映射到三维对象以产生针织品模型。

6. 发明授权

US07205384B2 Process for preparing peptidyl heterocyclic ketone derivatives 有权
标题翻译：肽基杂环酮衍生物的制备方法
公开(公告)号：US07205384B2
公开(公告)日：2007-04-17
申请号：US10902755
申请日：2004-07-29
申请人： Michael Breslav , Bruce Harris , Birdella Kenney , Thomas Maier , Armin Roessler , Frank Villani , Ulrich Weigl , Fan Zhang-Plasket , Hua Zhong
发明人： Michael Breslav , Bruce Harris , Birdella Kenney , Thomas Maier , Armin Roessler , Frank Villani , Ulrich Weigl , Fan Zhang-Plasket , Hua Zhong
IPC分类号： A61K38/00
CPC分类号： C07D277/64 , C07D417/12
摘要： The present invention relates to novel processes for the preparation of peptidyl heterocyclic ketones of the general formula (I) wherein all variables are as herein defined. The present invention further relates to novel pharmaceutical salts and processes for their preparation. The peptidyl heterocyclic ketones of formula (I) are potent and selective inhibitors of tryptase, useful for the treatment and prevention of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis.
摘要翻译：本发明涉及制备通式（I）的肽基杂环酮的新方法，

7. 发明授权

US07132544B2 Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof 有权
公开(公告)号：US07132544B2
公开(公告)日：2006-11-07
申请号：US11243277
申请日：2005-10-04
申请人： Hua Zhong , Silke Dubberke , Stefan Müller , Armin Rossler , Thomas W. Schultz , Daniel J. Korey , Thomas Otten , Donald G. Walker , Ahmed Abdel-Magid
发明人： Hua Zhong , Silke Dubberke , Stefan Müller , Armin Rossler , Thomas W. Schultz , Daniel J. Korey , Thomas Otten , Donald G. Walker , Ahmed Abdel-Magid
IPC分类号： C07D401/04 , C07D233/64
CPC分类号： C07D401/04 , C07D213/51
摘要： The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification below. The present invention further relates to a process for preparing the compound of formula (II) and novel crystalline structures of the compound of formula (II).

8. 发明授权

US07067671B2 Process for the preparation of tetrasubstituted imidazole derivatives and novel crystalline structures thereof 失效
标题翻译：制备四取代咪唑衍生物的方法及其新型晶体结构
公开(公告)号：US07067671B2
公开(公告)日：2006-06-27
申请号：US10081553
申请日：2002-02-22
申请人： Hua Zhong , Silke Dubberke , Stefan Müller , Armin Rossler , Thomas W. Schultz , Daniel J. Korey , Thomas Otten , Donald G. Walker , Ahmed Abdel-Magid
发明人： Hua Zhong , Silke Dubberke , Stefan Müller , Armin Rossler , Thomas W. Schultz , Daniel J. Korey , Thomas Otten , Donald G. Walker , Ahmed Abdel-Magid
IPC分类号： C07D401/04
CPC分类号： C07D401/04 , C07D213/51
摘要： The present invention relates to a process for preparing tetrasubstituted imidazole derivatives of the general formula (I) wherein R1, R2, R3 and R4 are as defined in the specification below. The present invention further relates to a process for preparing the compound of formula (II) and novel crystalline structures of the compound of formula (II).
摘要翻译：本发明涉及制备通式（I）的四取代咪唑衍生物的方法，其中R 1，R 2，R 3和R 3， R 4如下面的说明书中所定义。本发明还涉及制备式（II）化合物和式（II）化合物的新结晶结构的方法。

9. 发明授权

US09128953B1 Asynchronous multi-node filesystem coordinated replication 有权
标题翻译：异步多节点文件系统协调复制
公开(公告)号：US09128953B1
公开(公告)日：2015-09-08
申请号：US12460677
申请日：2009-07-21
申请人： Pratap Singh , Hua Zhong
发明人： Pratap Singh , Hua Zhong
IPC分类号： G06F17/30
CPC分类号： G06F17/30174 , G06F17/30212 , G06F17/3023
摘要： A system for replicating a filesystem running on multiple nodes comprising an originator system and a replica system. The originator system includes a plurality of nodes. The replica system includes a plurality of nodes and a processor. The plurality of nodes of the replica system are paired with the plurality of nodes of the originator system. The processor is configured to receive an indicator of a node of the plurality of nodes of the replica system finishing replication for a view of a filesystem at a point in time. The processor is further configured to indicate that replication for the view of the filesystem is complete in the event that all replica system nodes have received their indication for the view.
摘要翻译：用于复制在包含发起者系统和副本系统的多个节点上运行的文件系统的系统。发起者系统包括多个节点。复制系统包括多个节点和处理器。复制系统的多个节点与发起者系统的多个节点配对。所述处理器被配置为接收所述副本系统的所述多个节点中的节点的指示符，以完成针对文件系统的视图在某个时间点的复制。处理器还被配置为指示在所有副本系统节点已经接收到其对于视图的指示的情况下，用于文件系统的视图的复制是完整的。

10. 发明授权

US08900150B2 Intracardiac imaging system utilizing a multipurpose catheter 有权
标题翻译：使用多用途导管的心内成像系统
公开(公告)号：US08900150B2
公开(公告)日：2014-12-02
申请号：US12982968
申请日：2010-12-31
申请人： D. Curtis Deno , Anthony D. Hill , Hua Zhong
发明人： D. Curtis Deno , Anthony D. Hill , Hua Zhong
IPC分类号： A61B8/12 , A61B5/06 , A61B18/14 , A61B18/00 , A61B19/00 , A61B5/00
CPC分类号： A61B8/0883 , A61B5/0422 , A61B5/06 , A61B5/061 , A61B5/063 , A61B5/7217 , A61B8/12 , A61B8/463 , A61B8/5238 , A61B18/14 , A61B34/20 , A61B2018/00755 , A61B2018/00839 , A61B2018/00875 , A61B2034/2051 , A61B2034/2053 , A61B2562/0209 , A61B2562/046 , Y10S128/916
摘要： A three dimensional physiological mapping system utilizing an intracardiac echo catheter capable of being located in six degrees of freedom by a visualization, navigation, or mapping system. An echocardiography image of the intracardiac echo catheter may be projected within a geometric model of the visualization, navigation, or mapping system where the location of the projected image is adjusted in response to user input identifying a structure present in the echocardiography image and the geometric model.
摘要翻译：利用心内回波导管的三维生理测绘系统能够通过可视化，导航或绘图系统位于六自由度。心内回波导管的超声心动图可以投射在可视化，导航或映射系统的几何模型内，其中根据用户输入来调整投影图像的位置，该用户输入识别存在于超声心动图图像和几何模型中的结构。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式