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1. 发明授权

US09561366B2 Conditional electrical stimulation 有权
标题翻译：有条件的电刺激
公开(公告)号：US09561366B2
公开(公告)日：2017-02-07
申请号：US13237216
申请日：2011-09-20
申请人： Xuan K. Wei , Eric H. Bonde
发明人： Xuan K. Wei , Eric H. Bonde
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61N1/3606 , A61N1/36107 , A61N1/36139 , A61N1/36175 , A61N1/36178
摘要： In general, the disclosure describes techniques for providing conditional electrical stimulation to a patient for pelvic health. An implantable medical device (IMD) may adjust the delivery cycle of the electrical stimulation applied to a patient in response to receiving a delivery cycle parameter associated with one or more of the following: a time in a time schedule, a control device output from a control device, and physiological information from a physiological information sensing device. As an example, the IMD may monitor a status of one or more inputs of the IMD and adjust the delivery cycle of the electrical stimulation applied to the patient based on the status of the input(s).
摘要翻译：通常，本公开描述了为患者提供有条件的电刺激以进行盆腔健康的技术。可植入医疗装置（IMD）可以响应于接收与以下一个或多个相关联的递送周期参数来调整施加到患者的电刺激的递送周期：时间表中的时间，来自控制装置和来自生理信息感测装置的生理信息。作为示例，IMD可以监视IMD的一个或多个输入的状态，并且基于输入的状态来调整施加到患者的电刺激的递送周期。

2. 发明申请

US20120130444A1 INCONTINENCE THERAPY 有权
标题翻译：不良治疗
公开(公告)号：US20120130444A1
公开(公告)日：2012-05-24
申请号：US13265702
申请日：2010-04-09
申请人： Xuan K. Wei , Eric H. Bonde , Keith A. Miesel , Mark S. Lent , Gregory F. Molnar
发明人： Xuan K. Wei , Eric H. Bonde , Keith A. Miesel , Mark S. Lent , Gregory F. Molnar
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61N1/0514 , A61N1/0551 , A61N1/36128 , A61N1/36135 , A61N1/37235 , A61N1/37252
摘要： Techniques for managing urinary or fecal incontinence include delivering a first type of therapy to generate a first physiological response and, upon detecting a trigger event, delivering a second type of therapy to generate a second physiological response. The first type of therapy can be delivered on a substantially regular basis, while the second type of therapy is delivered as needed to provide an additional boost of therapy. The trigger event for activating the delivery of the second type of therapy may include input from a sensor that indicates a bladder condition, patient activity level or patient posture, or patient input. In some examples, the therapy is stimulation therapy.
摘要翻译：用于管理尿失禁或大便失禁的技术包括递送第一类型的治疗以产生第一生理反应，并且在检测到触发事件时，递送第二类型的治疗以产生第二生理反应。第一种类型的治疗可以基本上定期地递送，而第二种类型的治疗根据需要被递送以提供额外的治疗效果。用于激活第二类治疗的递送的触发事件可以包括来自传感器的输入，其指示膀胱状况，患者活动水平或患者姿势或患者输入。在一些例子中，治疗是刺激疗法。

3. 发明申请

US20120010680A1 CONDITIONAL ELECTRICAL STIMULATION 有权
标题翻译：条件电刺激
公开(公告)号：US20120010680A1
公开(公告)日：2012-01-12
申请号：US13237216
申请日：2011-09-20
申请人： Xuan K. Wei , Eric H. Bonde
发明人： Xuan K. Wei , Eric H. Bonde
IPC分类号： A61N1/372 , A61N1/36
CPC分类号： A61N1/36007 , A61N1/3606 , A61N1/36107 , A61N1/36139 , A61N1/36175 , A61N1/36178
摘要： In general, the disclosure describes techniques for providing conditional electrical stimulation to a patient for pelvic health. An implantable medical device (IMD) may adjust the delivery cycle of the electrical stimulation applied to a patient in response to receiving a delivery cycle parameter associated with one or more of the following: a time in a time schedule, a control device output from a control device, and physiological information from a physiological information sensing device. As an example, the IMD may monitor a status of one or more inputs of the IMD and adjust the delivery cycle of the electrical stimulation applied to the patient based on the status of the input(s).
摘要翻译：通常，本公开描述了为患者提供有条件的电刺激以进行盆腔健康的技术。可植入医疗装置（IMD）可以响应于接收与以下一个或多个相关联的递送周期参数来调整施加到患者的电刺激的递送周期：时间表中的时间，来自控制装置和来自生理信息感测装置的生理信息。作为示例，IMD可以监视IMD的一个或多个输入的状态，并且基于输入的状态来调整施加到患者的电刺激的递送周期。

4. 发明授权

US10201702B2 Pelvic floor muscle training 有权
公开(公告)号：US10201702B2
公开(公告)日：2019-02-12
申请号：US13305405
申请日：2011-11-28
申请人： Eric H. Bonde , Xuan K. Wei
发明人： Eric H. Bonde , Xuan K. Wei
IPC分类号： A61N1/36 , A61N1/372
摘要： Electrical stimulation is delivered to a patient based on input from a patient indicative of an intent of the patient to contract a pelvic floor muscle or an attempt by the patient to contract the pelvic floor muscle. The electrical stimulation is configured to induce a contraction of the pelvic floor muscle of the patient to strengthen the pelvic floor muscle.

5. 发明申请

US20120136413A1 PELVIC FLOOR MUSCLE TRAINING 审中-公开
标题翻译：皮肤地板肌肉训练
公开(公告)号：US20120136413A1
公开(公告)日：2012-05-31
申请号：US13305405
申请日：2011-11-28
申请人： Eric H. Bonde , Xuan K. Wei
发明人： Eric H. Bonde , Xuan K. Wei
IPC分类号： A61N1/36
CPC分类号： A61N1/36007 , A61N1/36071 , A61N1/36107 , A61N1/36132 , A61N1/37247
摘要： Electrical stimulation is delivered to a patient based on input from a patient indicative of an intent of the patient to contract a pelvic floor muscle or an attempt by the patient to contract the pelvic floor muscle. The electrical stimulation is configured to induce a contraction of the pelvic floor muscle of the patient to strengthen the pelvic floor muscle.
摘要翻译：基于来自患者的输入，电刺激被递送到患者，该患者指示患者意图收缩盆底肌肉或患者尝试收缩盆底肌肉。电刺激被配置为诱导患者的盆底肌肉的收缩以加强盆底肌肉。

6. 发明授权

US09155885B2 Incontinence therapy 有权
标题翻译：失禁治疗
公开(公告)号：US09155885B2
公开(公告)日：2015-10-13
申请号：US13265702
申请日：2010-04-09
申请人： Xuan K. Wei , Eric H. Bonde , Keith A. Miesel , Mark S. Lent , Gregory F. Molnar
发明人： Xuan K. Wei , Eric H. Bonde , Keith A. Miesel , Mark S. Lent , Gregory F. Molnar
IPC分类号： A61N1/00 , A61N1/36 , A61N1/372
CPC分类号： A61N1/36007 , A61N1/0514 , A61N1/0551 , A61N1/36128 , A61N1/36135 , A61N1/37235 , A61N1/37252
摘要： Techniques for managing urinary or fecal incontinence include delivering a first type of therapy to generate a first physiological response and, upon detecting a trigger event, delivering a second type of therapy to generate a second physiological response. The first type of therapy can be delivered on a substantially regular basis, while the second type of therapy is delivered as needed to provide an additional boost of therapy. The trigger event for activating the delivery of the second type of therapy may include input from a sensor that indicates a bladder condition, patient activity level or patient posture, or patient input. In some examples, the therapy is stimulation therapy.
摘要翻译：用于管理尿失禁或大便失禁的技术包括递送第一类型的治疗以产生第一生理反应，并且在检测到触发事件时，递送第二类型的治疗以产生第二生理反应。第一种类型的治疗可以基本上定期地递送，而第二种类型的治疗根据需要被递送以提供额外的治疗效果。用于激活第二类治疗的递送的触发事件可以包括来自传感器的输入，其指示膀胱状况，患者活动水平或患者姿势或患者输入。在一些例子中，治疗是刺激疗法。

7. 发明授权

US08954162B2 Medical device implantation 有权
标题翻译：医疗器械植入
公开(公告)号：US08954162B2
公开(公告)日：2015-02-10
申请号：US11739982
申请日：2007-04-25
申请人： Eric H. Bonde , Martin T. Gerber
发明人： Eric H. Bonde , Martin T. Gerber
IPC分类号： A61M31/00 , A61B17/34 , A61N1/05 , A61N1/36 , A61B17/06 , A61B17/00
CPC分类号： A61N1/0526 , A61B17/06109 , A61B17/3468 , A61B2017/00946 , A61B2017/06052 , A61N1/0551 , A61N1/36071
摘要： The disclosure is directed to a method for implanting a medical device proximate to a target tissue site within an occipital region of a patient, such as proximate to an occipital nerve or a trigeminal nerve. The method comprises introducing an implant tool into a patient to define an insertion path to the target tissue site. The implant tool includes a shape memory cannula and a malleable needle at least partially disposed within an inner lumen of the cannula. The shape of the needle may be changed to accommodate different anatomical structures/features of the patient. Upon withdrawal of the needle from the cannula, the cannula may change shape, thereby changing the shape of the insertion path.
摘要翻译：本公开涉及一种用于将医疗设备植入接近患者枕骨区域内的目标组织部位（例如靠近枕骨神经或三叉神经）的方法。该方法包括将植入物工具引入患者以限定到目标组织部位的插入路径。植入物工具包括形状记忆套管和至少部分地设置在套管的内腔内的有韧性的针。可以改变针的形状以适应患者的不同解剖结构/特征。当针从套管中取出时，套管可以改变形状，从而改变插入路径的形状。

8. 发明授权

US08486089B2 Introducer for lead delivery 有权
标题翻译：引导员提供铅交货
公开(公告)号：US08486089B2
公开(公告)日：2013-07-16
申请号：US12706225
申请日：2010-02-16
申请人： Phillip C. Falkner , Eric H. Bonde , Dale F. Seeley , Patrick P. Senarith , Steven L. Waldhauser , Kendra Yasger
发明人： Phillip C. Falkner , Eric H. Bonde , Dale F. Seeley , Patrick P. Senarith , Steven L. Waldhauser , Kendra Yasger
IPC分类号： A61B19/00
CPC分类号： A61B17/3431 , A61B17/3401 , A61B17/3468 , A61B2017/3447 , A61M25/0026 , A61M25/0662 , A61M2025/0024 , A61M2025/0037 , A61N1/0551
摘要： Devices and methods for implanting leads along a spinal cord include an introducer having a main body defining a lumen and one or more collapsible and expandable side sheaths attached to the main body. The side sheaths may be collapsed as the introducer is positioned in a desired location of a patient to maintain a low profile. Once the introducer is placed, the side sheaths may be expanded to receive a lead. A lead may also be inserted through a lumen of the main body. Once the leads are inserted, the introducer may be withdrawn over the leads, leaving the leads implanted in the desired region in a desired orientation.
摘要翻译：用于沿脊髓植入引线的装置和方法包括导引器，其具有限定内腔的主体和附接到主体的一个或多个可折叠和可扩张的侧护套。当导引器位于患者的期望位置以保持低轮廓时，侧鞘可能会折叠。一旦放置引导器，侧护套可以被扩张以接收引线。引线也可以插入通过主体的内腔。一旦导线被插入，导引器可以被引出在引线上，留下导线以期望的方向注入所需区域。

9. 发明申请

US20120323254A1 MEDICAL ASSEMBLIES AND METHODS FOR IMPLEMENTATION OF MULTIPLE MEDICAL LEADS THROUGH A SINGLE ENTRY 审中-公开
标题翻译：通过单次进入实施多个医疗领域的医疗组装和方法
公开(公告)号：US20120323254A1
公开(公告)日：2012-12-20
申请号：US13525560
申请日：2012-06-18
申请人： Eric H. Bonde , Phillip C. Falkner , John B. Horrigan , Stuart R. MacDonald , Madeline A. Mannion
发明人： Eric H. Bonde , Phillip C. Falkner , John B. Horrigan , Stuart R. MacDonald , Madeline A. Mannion
IPC分类号： A61N1/05 , A61M25/09 , A61B17/34
摘要： Assemblies and methods provide for implantation of multiple medical leads to a defined space within the body, such as the epidural space, through a single entry. A catheter having multiple lumens or alternatively a single oblong lumen may be used. A distal end of the catheter enters the defined space through the single entry such that the distal ends of the multiple lumens or the oblong lumen are present in the defined space. Medical leads are introduced through the multiple lumens or the oblong lumen into the defined space. In some cases, the distal end of the catheter may be deflectable to direct the medical leads within the defined space. In other cases, sheaths may be present within each lumen of the catheter where the sheaths may be extended into the defined space and deflect to direct the medical leads that are being passed through a lumen of the sheaths.
摘要翻译：组件和方法提供通过单个入口将多个医疗引线植入身体内的限定空间，例如硬膜外腔。可以使用具有多个腔或可选地单个长圆形管腔的导管。导管的远端通过单个入口进入限定的空间，使得多个管腔或长圆形管腔的远端存在于限定的空间中。医疗引线通过多个管腔或长圆形腔引入定义的空间。在一些情况下，导管的远端可以是可偏转的，以将医疗引线引导到限定的空间内。在其他情况下，护套可以存在于导管的每个内腔中，其中护套可以延伸到限定的空间中并且偏转以引导通过护套的内腔的医疗引线。

10. 发明授权

US08204575B2 Locating guide 失效
标题翻译：定位指南
公开(公告)号：US08204575B2
公开(公告)日：2012-06-19
申请号：US11835296
申请日：2007-08-07
申请人： Eric M. Stetz , Eric H. Bonde , Yelena G. Tropsha , Thomas Chun
发明人： Eric M. Stetz , Eric H. Bonde , Yelena G. Tropsha , Thomas Chun
IPC分类号： A61B5/05
CPC分类号： A61B90/39 , A61B90/11 , A61B2090/376 , A61B2090/3916 , A61B2090/3983 , A61N1/0551 , A61N1/08
摘要： A locating guide for locating a target tissue site within a patient includes a body, a first substantially radiopaque reference marker on the body, and a second substantially radiopaque reference marker extending from a major surface of the body. The reference markers provide reference points that extend in at least two dimensions, and may be useful for registering a medical image of tissue with an actual location on or within the patient in order to more accurately and precisely locate a target tissue site within the patient. In some embodiments, the second reference marker is oriented at a predetermined angle relative to the major surface of the body, and provides a guide that a clinician may reference in order to orient a medical element introducer when introducing the introducer into the patient to access a particular target tissue site.
摘要翻译：用于定位患者内的目标组织部位的定位引导件包括主体，身体上的第一基本上不透射线的参考标记以及从主体的主表面延伸的第二基本不透射线的参考标记。参考标记提供在至少两个维度上延伸的参考点，并且可用于将具有实际位置的组织的医学图像登记在患者身上或内部，以便更精确地和精确地定位患者内的目标组织部位。在一些实施例中，第二参考标记物相对于主体的主表面以预定角度定向，并且提供临床医生可引用的引导件，以便在将导引器引入患者时进行定位以导向医疗元件导入器特定目标组织部位。

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