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1. 发明授权

US11666280B2 Catheter having a fiber optic force sensor with a mirror having a patterned reflectance 有权
公开(公告)号：US11666280B2
公开(公告)日：2023-06-06
申请号：US17832975
申请日：2022-06-06
申请人： Lake Region Manufacturing, Inc.
发明人： John Michael Hayes , James F. Kelley
IPC分类号： A61B5/00 , A61B18/00
CPC分类号： A61B5/6852 , A61B5/0066 , A61B5/0084 , A61B2018/00577
摘要： An ablation catheter Has a spring assembly residing between an ablation head and a proximal catheter body. Three optical fibers extend through a lumen in the catheter body. Three mirrors supported by the ablation head face proximally but are spaced distally from the optical fibers. The mirrors are provided with a pattern of reflectance that varies along a radius from a central area of reflectance. Light of a respective defined power shines from each of the optical fibers to a corresponding one of the mirrors with a reflected percentage of the respective defined light power being reflected back to the optical fiber. A percentage of the reflected percentage of the respective defined light power is captured by and travels along each optical fiber to a dedicated light wave detector connected to a controller. From the percentage of the reflected percentage of the light of the respective defined power received by each detector, the controller is programmed to calculate whether an axial or lateral force is imparted to the ablation head and, if so, the magnitude and vector of those forces.

2. 发明授权

US11197750B2 Embolic protection device 有权
公开(公告)号：US11197750B2
公开(公告)日：2021-12-14
申请号：US15825528
申请日：2017-11-29
申请人： Lake Region Manufacturing, Inc.
发明人： Brian Chouinard , David Keary , Aran Murray
IPC分类号： A61F2/01 , A61M25/10
摘要： Disclosed herein are devices and methods for providing embolic protection in a patient's vascular system. In particular, the devices detailed herein are supported by a flexible scaffold that is coupled to a filter. When deployed into the peripheral or coronary vasculature of a patient, the embolic protection devices of the present disclosure collect and remove embolic debris as a prophylactic measure to lessen the risk of embolic associated complications.

3. 发明申请

US20210087426A1 POLYURETHANE UREA-CONTAINING ADIPIC ACID DIHYDRAZIDE COATING WHERE ACTIVE HYDROGENS REACT WITH THE GLYCIDOL EPOXY GROUP TO FORM A DIOL 有权
公开(公告)号：US20210087426A1
公开(公告)日：2021-03-25
申请号：US17112257
申请日：2020-12-04
申请人： Lake Region Manufacturing, Inc.
发明人： Peter A. Edwards
IPC分类号： C09D175/04 , C08G18/38 , C08G18/75 , C08G18/76 , C08G18/58 , C08G18/48 , C08G18/34 , C08G18/24 , C08G18/32
摘要： A coating composition containing added diol functionality to a urethane, a urea, or polyurethane urea functional resin where an adipic acid dihydrazide chain extender, or free adipic acid dihydrazide active hydrogens react with the oxirane group found in glycidol is described. The combination of diisocyanate, a polyether segment, optionally at least one polyester diol segment, optionally at least one poly(tetrahydrofuran) diol segment, optionally and at least one dimethylol propionic acid diol segment, at least one dihydrazide segment and glycidol compound introduces an increased hydrophilic structure, by diol addition, in compositions that are usable as coatings, on for example, medical devices.

4. 发明申请

US20210023339A1 Catheter With Embedded Core Wires 有权
公开(公告)号：US20210023339A1
公开(公告)日：2021-01-28
申请号：US16938935
申请日：2020-07-25
申请人： Lake Region Manufacturing, Inc
发明人： John Michael Hayes
IPC分类号： A61M25/01 , A61M25/00 , A61M25/09
摘要： A kink-resistance catheter has at least a first pair of core wires residing in the catheter body on opposed side of a catheter lumen. The core wires have relatively stiff proximal ends but taper toward their distal ends. The tapered construction provides the core wires with a degree of distal flexibility that helps the catheter advance along a vasculature to a site of interest without kinking. Moreover, the core wires greatly improve the torsional rigidity of the catheter so that rotation of the catheter's proximal end translates into a substantially equivalent rotation at the distal end. If desired, shaping ribbons are provided in the catheter body adjacent to the distal ends of the core wires. The shaping ribbons can be pre-bent before a surgical procedure to help the physician advance the catheter along the vasculature. Finally, the core wires provide the ability to push the catheter through the vasculature without the need for the catheter to go over a guidewire already in-situ in the vasculature.

5. 发明授权

US09345854B2 Distal shield for packaged guidewire 有权
标题翻译：用于包装导丝的远端屏蔽
公开(公告)号：US09345854B2
公开(公告)日：2016-05-24
申请号：US13685009
申请日：2012-11-26
申请人： Lake Region Manufacturing, Inc.
发明人： Rick Benesh
IPC分类号： A61M25/00 , B65D73/00 , A61M25/09
CPC分类号： A61M25/002 , A61M25/09 , B65D73/0021
摘要： A distal tip protector, protection shield, or packaging insert to protect the distal segment of a guidewire projecting from a guidewire carrier.
摘要翻译：远端尖端保护器，保护屏蔽或包装插入物，用于保护从导丝线载体突出的导丝的远端部分。

6. 发明授权

US09255173B2 Oxirane (ethylene oxide) polyurethane coatings 有权
标题翻译：环氧乙烷（环氧乙烷）聚氨酯涂料
公开(公告)号：US09255173B2
公开(公告)日：2016-02-09
申请号：US13834988
申请日：2013-03-15
申请人： LAKE REGION MANUFACTURING, INC.
发明人： Peter Anthony Edwards
IPC分类号： C09D163/00 , C09D175/04 , C08G59/00 , C08G18/00 , C08G18/28 , C08G59/22 , C08G59/28 , C08G59/32 , C08G18/10 , C08G65/32 , C08G65/332 , C08G18/08 , C08G18/48 , C08G18/66 , C08G18/73 , C08G18/76 , C09D175/08 , C08G18/40 , C08G18/42
CPC分类号： C09D175/08 , C08G18/0823 , C08G18/0866 , C08G18/4018 , C08G18/4238 , C08G18/4808 , C08G18/4833 , C08G18/4854 , C08G18/6692 , C08G18/73 , C08G18/7671 , C08G2210/00 , C08G18/12 , C08G18/2845 , C08G18/3834 , C08G18/10
摘要： The present invention relates to hydrophilic, i.e., water loving coatings (hereafter referred to as “WLC”). Polyurethane epoxy alkylene oxide coatings usable as coatings on for example, medical devices are a preferred WLC.
摘要翻译：本发明涉及亲水性，即水性涂层（以下称为“WLC”）。可用作例如医疗装置的涂层的聚氨酯环氧环氧烷涂料是优选的WLC。

7. 发明授权

US07627382B2 Medical devices with aromatic polyimide coating 有权
标题翻译：具有芳香族聚酰亚胺涂层的医疗器械
公开(公告)号：US07627382B2
公开(公告)日：2009-12-01
申请号：US11137162
申请日：2005-05-25
申请人： Chris Minar , Andrew Senn , William Whealon , Bruce Rittenour
发明人： Chris Minar , Andrew Senn , William Whealon , Bruce Rittenour
IPC分类号： A61N1/04
CPC分类号： A61N1/056 , A61L29/085 , A61L31/10 , A61M25/0045 , A61M25/09 , A61M2025/09091 , C08L79/08
摘要： Medical devices that include on at least some portion thereof an aromatic polyimide of the structure: wherein R is a tetravalent aromatic radical, preferably containing at least one ring of six carbon atoms, said ring characterized by benzenoid unsaturation, the four carbonyl groups being attached directly to separate carbon atoms in a ring and each pair of carbonyl groups being attached to adjacent carbon atoms in a ring of the R radical; and wherein R′ is a divalent benzenoid radical selected from the group consisting of wherein R″ is selected from the group consisting of an alkylene chain having 1-3 carbon atoms, R′″ and R″″ are selected from the group consisting of alkyl and aryl. In one embodiment the medical device is a coated lead body.Coated guide wires are a further embodiment.Methods of application are a further embodiment.
摘要翻译：在其至少一部分上包含以下结构的芳族聚酰亚胺的医疗装置：其中R是四价芳族基团，优选含有至少一个六个碳原子的环，所述环的特征在于苯不饱和键，四个羰基直接连接以分离环中的碳原子，并且每对羰基连接到R基团的环中的相邻碳原子; 并且其中R'是选自下组的二价苯环基，其中R“选自具有1-3个碳原子的亚烷基链，R”和R“'选自由烷基和芳基构成的基团。在一个实施例中，医疗装置是涂覆的引线体。涂覆导丝是另一个实施例。应用方法是另一实施例。

8. 发明申请

US20090143702A1 Non-metallic guide wire 审中-公开
标题翻译：非金属导丝
公开(公告)号：US20090143702A1
公开(公告)日：2009-06-04
申请号：US12367375
申请日：2009-02-06
申请人： Mark G. Fleischhacker
发明人： Mark G. Fleischhacker
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guide wire having a non-metallic, non-woven core wire is disclosed. Monofilar, polymeric fibers of multifilar helically-wound non-metallic fibers are preferred core wire materials. The guide wire optionally includes further coatings and other materials on the core wire. In one embodiment, a non-metallic distal coil wire is disclosed. The guide wire of this invention is particularly useable for magnetic resonance imaging applications.
摘要翻译：公开了一种具有非金属非编织芯线的导丝。多股螺旋缠绕非金属纤维的单丝聚合物纤维是优选的芯线材料。引导线可选地包括在芯线上的其它涂层和其它材料。在一个实施例中，公开了非金属远端线圈线。本发明的引导丝特别适用于磁共振成像应用。

9. 发明申请

US20010021831A1 Hollow lumen cable apparatus 有权
标题翻译：中空管线电缆设备
公开(公告)号：US20010021831A1
公开(公告)日：2001-09-13
申请号：US09780658
申请日：2001-02-09
申请人： Lake Region Manufacturing, Inc.
发明人： Mark G. Fleischhacker , Joseph F. Fleischhacker JR. , Thomas E. Hargreaves , Donald W. Hanson
IPC分类号： A61M025/00
CPC分类号： A61B17/3207 , A61B17/29 , A61B17/32002 , A61B18/245 , A61M1/1008 , A61M1/101 , A61M1/122 , A61M1/125 , A61M25/0105 , A61M25/09 , A61M2025/09066 , A61M2025/09091 , A61M2025/09191
摘要： A hollow lumen cable is formed by helically winding inner and outer coils with the helices of each coil being in an abutting relationship and the outer coil inner peripheral diameter being less than the outer peripheral diameter of the inner coil. Preferably, each coil is multifilar. After the coils are wound, an unwinding force is applied to the outer coil and the inner coil is inserted into the outer coil to have its winding inclined opposite to that of the outer coil; and thence, the outer coil is allowed to contract to form an interference fit with the inner coil. The cable may be incorporated as part of a medical apparatus. The cable is bendable about the tight radii and has a high torque transfer resolution while having a small cable outer diameter, a relatively long life, and has a hollow lumen in which there is no structure or through which fluid, wires or medial devices may pass. Also, there is a handle assembly for operating a movable guide wire between positions for straightening the guide wire and allowing it to assume its generally J-shape.
摘要翻译：通过螺旋地缠绕内圈和外圈，每个线圈的螺旋处于邻接关系并且外圈的内圆周直径小于内圈的外圆周直径形成中空的管腔电缆。优选地，每个线圈是多相的。在卷绕线圈之后，向外部线圈施加退绕力，并且将内部线圈插入到外部线圈中以使其卷绕与外部线圈相反倾斜; 从而允许外部线圈收缩以与内部线圈形成过盈配合。电缆可以作为医疗装置的一部分并入。电缆可以围绕紧密的半径弯曲，并且具有高的扭矩传递分辨率，同时具有小的电缆外径，寿命较长，并且具有中空的管腔，其中不存在流体，电线或中间装置可以通过的结构。而且，还有一个手柄组件，用于在可引导导线的平直位置和使其呈现大致J形的位置之间操作可动导丝。

10. 发明授权

US5634897A Rheolytic occlusion removal catheter system and method 失效
标题翻译：溶血性闭塞导管系统及方法
公开(公告)号：US5634897A
公开(公告)日：1997-06-03
申请号：US134089
申请日：1993-10-08
申请人： Creg W. Dance , Steven J. Erb
发明人： Creg W. Dance , Steven J. Erb
IPC分类号： A61B17/22 , A61M1/00
CPC分类号： A61B17/32037 , A61B17/22 , A61M1/0058 , A61B2017/22038 , A61M2205/32
摘要： A catheter for insertion in body vessels for removing occlusions or obstructions such as thrombus, clot, plaque and other vascular or arterial deposits without generating distal emboli. Removal of freshly or recently formed obstructions is a preferred application. Concurrently or subsequently, suction or aspiration removal of the resulting occlusion debris is disclosed. A catheter system of this invention comprises elongate, hollow, inner and outer coaxial catheters having distal and proximal ends. The distal end of the outer catheter terminates short of the distal end of the inner catheter. The catheters may be independently movable with respect to each other. The inner catheter wall defines a central lumen which fluidically couples the proximal and distal ends of the inner catheter and through which a guidewire can pass. The central lumen has a reduced diameter distal portion which, with an occluder means (e.g., a guidewire), is adapted to restrict distal fluid delivery therethrough. The distal end of the inner catheter is fluidically coupled to a diffusion manifold which includes a plurality of fluid diffusion orifices. Located between the diffusion manifold and the distal end of the outer catheter is a diffuser, The diffuser, which may be fixedly or rotatively mounted, is located so that fluid exiting from the diffusion orifices impinges thereon and is dispersed toward the occlusion.
摘要翻译：用于插入体内血管的导管，用于去除闭塞或障碍物，如血栓，凝块，斑块和其他血管或动脉沉积物，而不产生远端栓塞。清除新近或最近形成的障碍物是优选的应用。同时或随后，公开了吸入或抽吸所得到的闭塞碎片。本发明的导管系统包括具有远端和近端的细长，中空，内和外同轴导管。外导管的远端终止于内导管的远端。导管可以相对于彼此独立地移动。内导管壁限定了一个中心管腔，其与内导管的近端和远端流体连接，并且导丝可以通过该内导管。中心腔具有直径减小的远端部分，其具有封闭器装置（例如，导丝），适于限制远端流体通过其输送。内导管的远端流体耦合到包括多个流体扩散孔的扩散歧管。位于扩散歧管和外导管的远端之间的是扩散器。可以固定地或可旋转地安装的扩散器被定位成使得从扩散孔排出的流体撞击在其上并且朝向闭塞分散。

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