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    • 3. 发明授权
    • Detection/stimulation microlead with enhanced positioning
    • 检测/刺激microlead与增强的定位
    • US09248271B2
    • 2016-02-02
    • US14079298
    • 2013-11-13
    • SORIN CRM S.A.S.
    • Willy RégnierNicolas Shan
    • A61N1/00A61N1/05
    • A61N1/05A61N1/057
    • A microlead includes exposed areas forming stimulation electrodes. The microlead further includes a stimulation zone (ZS) defined by a first preshape of the microcable at the distal end thereof, in a region including the electrodes (30). The microlead further includes a retention zone (ZR) including a retainer shape adapted to abut the wall of the target vessel. The microlead further includes a stretching zone (ZEL) proximal to the retention zone. The stretching zone may be defined by a shape adapted to make the region elastically deformable in the longitudinal direction under the effect of an axial traction/compression stress. The axial traction/compression stiffness in the elongation zone is lower than that in the retention and stimulation areas.
    • 微孔包括形成刺激电极的暴露区域。 所述微引线还包括在包括所述电极(30)的区域中由所述微电极在其远端处的第一预塑膜限定的刺激区(ZS)。 微针还包括保持区(ZR),其包括适于邻接目标血管壁的保持器形状。 微珠还包括靠近保留区的拉伸区(ZEL)。 拉伸区域可以由适于使区域在轴向牵引/压缩应力的作用下在纵向方向上弹性变形的形状来限定。 延伸区域的轴向牵引/压缩刚度低于保留和刺激区域。
    • 4. 发明授权
    • Ventricular capture testing by analysis of an endocardial acceleration signal in an active implantable medical device
    • 通过分析活动植入式医疗装置中的心内膜加速度信号进行心室捕获测试
    • US09089711B2
    • 2015-07-28
    • US13942596
    • 2013-07-15
    • SORIN CRM S.A.S.
    • Lionel GiorgisAmel Amblard
    • A61N1/00A61N1/37G06K9/00A61N1/39A61N1/365
    • A61N1/3702A61N1/36578A61N1/371A61N1/3925G06K9/00536
    • A processor-based method for use with an active implantable medical device for cardiac pacing, resynchronization, and/or defibrillation includes forming a plurality of first and second endocardial acceleration vectors using a plurality of endocardial acceleration signals acquired using stimulation to cause capture and a spontaneous rhythm of the patient in the absence of ventricular pacing, respectively. An at least two dimension space is created using the first and second endocardial acceleration vectors, including two subspaces corresponding to the presence and absence of capture, respectively. Ventricular capture is tested for after acquiring a new endocardial acceleration signal. The testing includes forming a new endocardial acceleration signal based on the new vector. Presence or absence of capture is determined for the new signal based on the position of the new vector relative to the two subspaces.
    • 用于心脏起搏,再同步和/或除颤的主动植入医疗装置的基于处理器的方法包括使用多次使用刺激获得的心内加速度信号形成多个第一和第二心内膜加速度矢量以引起捕获和自发 分别在不存在心室起搏的情况下患者的节律。 使用第一和第二心内膜加速度矢量创建至少两个维度空间,其包括分别对应于存在和不存在捕获的两个子空间。 在获得新的心内膜加速度信号后测试心室捕获。 该测试包括基于新向量形成新的心内膜加速度信号。 基于新矢量相对于两个子空间的位置,确定新信号的存在或不存在。
    • 5. 发明授权
    • Electrical feedthrough in a metal wall of a housing of an active medical device and method of making the same
    • 有源医疗装置的壳体的金属壁中的电馈通及其制造方法
    • US09083161B2
    • 2015-07-14
    • US14034366
    • 2013-09-23
    • SORIN CRM S.A.S.
    • Bertrand BoutaudHélène Viatgé
    • H02G3/22H02G3/02A61N1/375
    • H02G3/02A61N1/3754H01G4/35Y10T29/49155Y10T29/49162Y10T29/49165
    • A method for making an hermetic and electrically insulating feedthrough in the metal wall of a housing of a device, preferably of an active medical device, is disclosed. The method includes: a) forming electrically insulating layers (24, 26) on each of the internal and external sides of the wall (10), b) on the internal side of the wall, forming a non-through groove with a closed contour (30) defining in the wall a metal islet (28) that is physically and electrically isolated from the rest of the wall, by removing the entire thickness of the electrically insulating internal layer (26) and the wall (10), leaving intact a sufficient thickness of the electrically insulating external layer (24) so that the external layer mechanically supports the metal islet, and c) on the external and internal sides respectively, exposing pads (34, 36) for making an electrical contact to the metallic islet, by a localized removal of material of the electrically insulating external and internal layers (24, 26), respectively.
    • 公开了一种用于在装置的壳体的金属壁中制造气密和电绝缘馈通的方法,优选地为主动医疗装置。 该方法包括:a)在壁的内侧上的壁(10)的内侧和外侧的每一侧上形成电绝缘层(24,26),b)形成具有封闭轮廓的非贯通槽 (30),通过去除所述电绝缘内层(26)和所述壁(10)的整个厚度,在所述壁中限定与所述壁的其余部分物理和电隔离的金属岛(28),从而保持完整 电绝缘外层(24)的足够的厚度使得外层机械地支撑金属岛,以及c)分别在外侧和内侧,用于与金属岛形成电接触的暴露焊盘(34,36) 通过分别去除电绝缘的外层和内层(24,26)的材料。
    • 6. 发明授权
    • Retractable screw intracardiac lead for cardiac stimulation and/or defibrillation
    • 用于心脏刺激和/或除颤的可伸缩螺丝心脏内铅
    • US09037265B2
    • 2015-05-19
    • US12768588
    • 2010-04-27
    • Jean-Francois Ollivier
    • Jean-Francois Ollivier
    • A61N1/00A61N1/05
    • A61N1/0573A61N1/0472A61N1/05A61N1/057
    • A retractable screw-type stimulation or defibrillation intracardiac lead is disclosed. According to one embodiment, the lead comprises a flexible hollow sheath (12) having at its distal end a lead head (10) and a connector (66) at its proximal end. The connector comprises a pin (62) connected to a lead head electrode (18). The lead head comprises a tubular body (28), at least one electrode (18, 20) for stimulation or defibrillation, a moving element translationally and rotationally moving within the tubular body in a helical motion, an anchoring screw (24) axially moving with respect to the tubular body, and a deployment mechanism (22) to deploy the anchoring screw out of the tubular body (28). The lead is a co-radial type, and the moving element (26) secured to the anchoring screw is connected to the tubular body (28) by a helical guide (46) and a coupling finger (56) protruding between two successive turns of the helical guide (46) for transforming a rotary movement imparted to the lead body in a deployment or retraction movement of the moving element (26). The helical guide (46) is resiliently compressible, with a free end (52) with a flat area (54) facing a flange (38) in vis-à-vis, so as to pinch the coupling finger (56) and to perform the function of a clutch limiting the torque transmitted to the anchoring screw by the rotation of the lead body, even in case of continuation of this rotation.
    • 公开了一种可伸缩的螺旋型刺激或除颤心脏内的铅。 根据一个实施例,引线包括柔性中空护套(12),其远端处具有引导头(10)和在其近端处的连接器(66)。 连接器包括连接到引线头电极(18)的引脚(62)。 引导头包括管状体(28),用于刺激或除颤的至少一个电极(18,20),以螺旋运动在管状体内平移和旋转移动的移动元件,与轴向移动的锚定螺钉(24) 相对于管状体,以及展开机构(22),用于将锚固螺钉展开出管状体(28)。 引导件是同向径向型,并且固定到锚定螺钉的移动元件(26)通过螺旋引导件(46)和连接指状件(56)连接到管状体(28),联接指状物(56)在两个连续的 所述螺旋引导件(46)用于在所述移动元件(26)的展开或缩回运动中变换被赋予所述引线主体的旋转运动。 螺旋引导件(46)是可弹性压缩的,具有相对于相对的面向凸缘(38)的平坦区域(54)的自由端(52),以便夹紧联接手指(56)并执行 离合器的功能,即使在继续旋转的情况下也限制了通过引线体的旋转而传递到锚定螺钉的扭矩。
    • 8. 发明授权
    • Pacing lead for a left cavity of the heart, implanted in the coronary system
    • 心脏左心室起搏,植入冠状动脉系统
    • US09014822B2
    • 2015-04-21
    • US13960640
    • 2013-08-06
    • Sorin CRM S.A.S.
    • Jean-François Ollivier
    • A61N1/05
    • A61N1/0587A61N1/056A61N1/0573A61N2001/0585
    • A pacing lead for a left cavity of the heart, implanted in the coronary system. This lead (24) includes a lead body with a hollow sheath (26, 28) of deformable material, having a central lumen open at both ends, and at least one telescopic microcable (42) of conductive material. The microcable slides along the length of the lead body and extends beyond the distal end (32) thereof. The party emerging beyond the distal end is an active free part (34) comprising a plurality of distinct bare areas (36, 38, 50, 50′, 50″), intended to come into contact (40) with the wall of a target vein (22) of the coronary system (14-22), so as to form a network of stimulation electrodes electrically connected together in parallel. The microcable further comprises, proximally, a connector to a generator of active implantable medical device such as a pacemaker or a resynchronizer.
    • 心脏左腔的起搏线,植入冠状动脉系统。 该引线(24)包括具有可变形材料的中空护套(26,28)的引线本体,其具有在两端敞开的中心管腔和至少一个导电材料的可伸缩微电缆(42)。 微型可滑动件沿着引线体的长度滑动并且延伸超出其远端(32)。 出现在远端之外的派对是主动的自由部分(34),其包括多个不同的裸露区域(36,38,50,50',50“),其旨在与目标的壁接触(40) 静脉(22),以形成并联电连接在一起的刺激电极网络。 微型电缆还包括近端地连接到主动植入式医疗装置(例如起搏器或再同步器)的发生器。
    • 9. 发明申请
    • PACING CONFIGURATION FOR AN IMPLANTABLE MEDICAL DEVICE
    • 可植入医疗器械的配置
    • US20150005838A1
    • 2015-01-01
    • US14484415
    • 2014-09-12
    • SORIN CRM S.A.S.
    • Fabrizio RenestoLionel Giorgis
    • A61N1/365
    • A61N1/36578A61N1/3627A61N1/3682A61N1/3684A61N1/3686A61N1/3706
    • An implantable medical device includes a sensor configured to generate an endocardial acceleration (EA) signal representative of activity of a patient's heart. The device further includes one or more circuits configured to identify within the EA signal at least one EA signal component corresponding to at least one peak of endocardial acceleration, and extract from the at least one EA signal component at least two characteristic parameters. The one or more circuits are further configured to generate a composite index based on a combination of the at least two characteristic parameters, determine a plurality of values of the composite index for a plurality of pacing configurations, and select a current pacing configuration from among the plurality of pacing configurations based on the plurality of values of the composite index.
    • 可植入医疗装置包括被配置为产生代表患者心脏活动的心内加速度(EA)信号的传感器。 该装置还包括一个或多个电路,其被配置为在EA信号内识别与至少一个心内膜加速度峰值对应的至少一个EA信号分量,并从至少一个EA信号分量提取至少两个特征参数。 所述一个或多个电路还被配置为基于所述至少两个特征参数的组合来生成复合索引,确定多个起搏配置的复合索引的多个值,并且从所述多个起搏配置中选择当前起搏配置 基于复合索引的多个值的多个起搏配置。