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1. 发明公开

US20230355313A1 SYSTEM AND METHOD FOR HARVESTING AND IMPLEMENTING HAIR GRAFT ON BODY SURFACE WITHOUT USING PRESERVATIVES 审中-公开
公开(公告)号：US20230355313A1
公开(公告)日：2023-11-09
申请号：US18356669
申请日：2023-07-21
申请人： Gajanan Anand Jadhao
发明人： Gajanan Anand Jadhao
IPC分类号： A61B34/10 , A61B17/3205 , A61F2/10 , A61F2/00
CPC分类号： A61B34/10 , A61B17/32053 , A61F2/10 , A61F2/0095 , A61B2034/105 , A61B2034/104 , A61B2017/00057
摘要： The present invention relates to a field of medical and hair transplant. More particularly, the present invention relates to a system and a method for harvesting and implementing hair graft on body surface. The system includes a harvester pointer communicatively connected with the processor, wherein the processor configured to instruct the harvester pointer to trace the marked points in the first area of the body surface of the subject and harvest the hairs through plunging mechanism; and an implanter pointer connected with the trimmer and communicatively connected with the processor, wherein the processor configured to instruct the implanter pointer to catch the trimmed hair graft from the trimmer and implant the hair graft at a particular marked point in the second area of the body surface of the subject through injection mechanism.

2. 发明授权

US11806445B2 Multi-layer skin substitute products and methods of making and using the same 有权
公开(公告)号：US11806445B2
公开(公告)日：2023-11-07
申请号：US16947053
申请日：2020-07-16
申请人： Wake Forest University Health Sciences
发明人： Anthony Atala , Gayoung Jeong , James J. Yoo , Sang Jin Lee , Young-Joon Seol
IPC分类号： A61F2/10 , A61L27/60 , B33Y80/00 , B33Y70/00 , C08L5/08 , A61L27/20 , C08L89/06 , C12N5/071 , B29C64/106 , B33Y10/00 , A61L27/18 , A61L27/38 , A61L27/52 , G01N33/50 , B29K75/00 , B29K105/00
CPC分类号： A61L27/60 , A61F2/10 , A61L27/18 , A61L27/20 , A61L27/3804 , A61L27/3813 , A61L27/3839 , A61L27/3891 , A61L27/52 , B29C64/106 , B33Y10/00 , B33Y70/00 , B33Y80/00 , C08L5/08 , C08L89/06 , C12N5/0698 , G01N33/502 , G01N33/5044 , A61F2210/0076 , A61F2240/001 , A61L2300/64 , A61L2430/34 , B29K2075/00 , B29K2105/0061 , C12N2502/091 , C12N2502/092 , C12N2502/094 , C12N2502/1305 , C12N2502/1323 , C12N2533/30 , C12N2533/54 , C12N2533/80
摘要： Provided are live, artificial, skin substitute products and methods of making and using the same, such as for wound treatment and compound testing, including compound testing for efficacy, toxicity, penetration, irritation and/or metabolism testing of drug candidates or compositions such as cosmetics.

3. 发明授权

US09492196B2 Hair implant anchors and systems and methods for use thereof 有权
标题翻译：头发植入物锚固件及其使用的系统和方法
公开(公告)号：US09492196B2
公开(公告)日：2016-11-15
申请号：US13511182
申请日：2010-11-24
申请人： Dvir Keren , Boaz Shenhav
发明人： Dvir Keren , Boaz Shenhav
IPC分类号： A61B17/34 , A61F2/10 , A61B17/00 , A61B17/04
CPC分类号： A61B17/3468 , A61B2017/00752 , A61B2017/00867 , A61B2017/00969 , A61B2017/0409 , A61B2017/0412 , A61B2017/0458 , A61F2/10
摘要： A hair implant anchor usable with a hair implant anchor deployment device for inserting one or more hairs into a tissue portion is provided. The hair implant anchor includes a holder configured to grip one or more hairs and one or more selectably deployable leaves formed with the holder. When the anchor is in its first configuration prior to implantation of the hairs, the leaves are constrained by the deployment device in a position generally parallel to an insertion axis, and in a second configuration, subsequent to implantation of the hair, the leaves adopt a position extended away from the insertion axis, thereby securing the holder and hair gripped thereby within the tissue portion. The invention also provides a method for use of the anchor, a hair implantation system, a multi-hair implantation system and a hair implantation assembly.
摘要翻译：提供了一种可用于将一个或多个毛发插入组织部分的头发植入物锚固器展开装置的头发植入物锚固件。头发植入物锚固件包括构造成夹持一个或多个毛发和由保持器形成的一个或多个可选择地展开的叶的保持器。当在植入毛发之前锚固件处于其第一构型时，叶片被展开装置约束在与插入轴线大致平行的位置，并且在第二构造中，在植入毛发之后，叶片采用位置从插入轴线延伸，从而将保持器和头发固定在组织部分内。本发明还提供了一种使用锚固件，头发植入系统，多头发植入系统和毛发植入组件的方法。

4. 发明授权

US09408691B2 Locator device for medical procedures on the body surface and method of its use 有权
标题翻译：身体表面医疗程序定位装置及其使用方法
公开(公告)号：US09408691B2
公开(公告)日：2016-08-09
申请号：US13831145
申请日：2013-03-14
申请人： Restoration Robotics, Inc.
发明人： Zander H. Oostman , Clifford A. Oostman, Jr.
IPC分类号： A61F2/10 , A61B17/00
CPC分类号： A61B90/39 , A61B34/30 , A61B90/37 , A61B2017/00752 , A61B2034/2065 , A61B2034/2068 , A61B2090/363 , A61B2090/3937 , A61B2090/3983 , A61B2090/3991 , A61F2/10 , A61F2/105
摘要： Devices and methods are described for performing a procedure on multiple adjacent segments of a body surface. The methods generally involve positioning a locator device on a body surface to delineate a first body surface segment. A first portion of the locator device may be moved while leaving a second portion of the locator device in place as a reference. The second portion of the locator may then be moved to reform the locator device and delineate a second segment of the body surface. Locator devices comprising two detachable portions are also described.
摘要翻译：描述了用于在身体表面的多个相邻节段上执行过程的装置和方法。所述方法通常涉及将定位装置定位在身体表面上以描绘第一身体表面段。定位装置的第一部分可以移动，同时使定位装置的第二部分作为参考就位。定位器的第二部分然后可被移动以改变定位装置并描绘身体表面的第二部分。还描述了包括两个可拆卸部分的定位装置。

5. 发明授权

US09314262B2 Follicular extraction method and device 有权
标题翻译：滤泡提取方法及装置
公开(公告)号：US09314262B2
公开(公告)日：2016-04-19
申请号：US11102550
申请日：2005-04-08
申请人： James A. Harris
发明人： James A. Harris
IPC分类号： A61B17/50 , A61B17/3205 , A61B17/34 , A61B17/00 , A61B17/30 , A61B17/32 , A61F2/10
CPC分类号： A61B17/32053 , A61B17/3468 , A61B2017/00752 , A61B2017/306 , A61B2017/320044 , A61F2/10
摘要： A method and device for the extraction of follicular units from a donor area on a patient. The method includes scoring the outer skin layers with a sharp punch, and then inserting a blunt punch into the incision to separate the hair follicle from the surrounding tissue and fatty layer. The method and device will significantly decrease the amount of follicular transection and increase the rate at which follicular units can be extracted.
摘要翻译：用于从患者的供体区域提取滤泡单位的方法和装置。该方法包括用锋利的冲头对外表皮层进行刻痕，然后将钝的冲头插入切口以将毛囊与周围组织和脂肪层分离。方法和装置将显着减少卵泡切除量，增加滤泡单位提取率。

6. 发明授权

US09289286B1 Hair transplant procedure with a time delay between implant site preparation and graft implantation 有权
标题翻译：头发移植程序，在植入部位准备和移植物植入之间具有时间延迟
公开(公告)号：US09289286B1
公开(公告)日：2016-03-22
申请号：US13453977
申请日：2012-04-23
申请人： Robert Michael Bernstein , William R. Rassman
发明人： Robert Michael Bernstein , William R. Rassman
IPC分类号： A61F2/10 , A61B17/34 , A61B17/00
CPC分类号： A61F2/10 , A61B17/3468 , A61B2017/00752
摘要： The method of implanting hair grafts in which implant wounds are made at sites for implanting the hair grafts and the implantation is delayed while the implant wounds are allowed a period to heal. The period for healing may be at least 18 hours after the wounds are made.
摘要翻译：植入头发移植物的方法在其中植入伤口在用于植入头发移植物和植入的部位处制造延迟，同时允许植入物伤口一段时间愈合。伤口愈合的时间可能至少在创伤18小时后。

7. 发明申请

US20150223840A1 Hair Restoration 审中-公开
标题翻译：头发修复
公开(公告)号：US20150223840A1
公开(公告)日：2015-08-13
申请号：US14679205
申请日：2015-04-06
申请人： Pilofocus, Inc.
发明人： Carlos K. Wesley , Trevor K. Lewis
IPC分类号： A61B17/34 , A61F2/10 , A61B17/32
CPC分类号： A61B17/3468 , A61B1/00087 , A61B1/313 , A61B17/320016 , A61B17/32002 , A61B17/32053 , A61B17/32093 , A61B17/34 , A61B90/50 , A61B2017/00752 , A61B2017/32004 , A61B2090/378 , A61B2217/005 , A61F2/10 , F04C2270/041
摘要： A surgical apparatus for hair removal surgery includes an extraction module, a visualization component and a bridging component. The extraction module includes independently controllable coring and clipping devices. The visualization component acts to align a target hair follicle with the extraction module. The extraction module also includes at least one independently controllable suction port. The instrument also includes a dissection module having a tissue separating device.
摘要翻译：用于脱毛手术的手术装置包括提取模块，可视化部件和桥接部件。提取模块包括可独立控制的取芯和夹持装置。可视化组件用于将目标毛囊与提取模块对齐。提取模块还包括至少一个可独立控制的吸入口。该仪器还包括具有组织分离装置的解剖模块。

8. 发明申请

US20150110750A1 METHODS FOR USING AUTOLOGOUS FIBROBLASTS TO ALTER SKIN IDENTITY 审中-公开
标题翻译：使用自动胶原蛋白改善皮肤特性的方法
公开(公告)号：US20150110750A1
公开(公告)日：2015-04-23
申请号：US14397877
申请日：2013-04-30
申请人： THE JOHNS HOPKINS UNIVERSITY , The Government of the United States of America, as represented by the Secretary of the Army
发明人： Luis Andres Garza , Sewon Kang , Jon H. Meyerle
IPC分类号： A61K35/12 , C12N5/071
CPC分类号： A61K35/33 , A61F2/10 , A61K35/36 , A61L27/3804 , A61L27/60 , C12N5/0625 , C12N5/0656
摘要： The present invention relates to the field of autologous fibroblasts. More specifically, the present invention provides methods and compositions comprising autologous fibroblasts and uses thereof to alter skin identity. In certain embodiments, volar fibroblasts can be expanded for the ability to induce volar skin at the stump site in amputees. In other embodiments, fibroblasts from haired scalp can be expanded to ameliorate alopecias.
摘要翻译：本发明涉及自体成纤维细胞的领域。更具体地，本发明提供包含自体成纤维细胞的方法和组合物及其用于改变皮肤特性的用途。在某些实施方案中，可以扩展成体成纤维细胞以在截肢者的残端部位诱导皮肤皮肤的能力。在其它实施方案中，来自头发头皮的成纤维细胞可以扩大以改善脱发。

9. 发明申请

US20150072963A1 COMPOSITIONS AND METHODS FOR REGULATING HAIR GROWTH 审中-公开
标题翻译：用于调节头发生长的组合物和方法
公开(公告)号：US20150072963A1
公开(公告)日：2015-03-12
申请号：US14386160
申请日：2013-03-15
申请人： The Trustees of the University of Pennsylvania
发明人： George Cotsarelis , Garret Fitzgerald , Luis Garza
IPC分类号： A61K8/49 , A61K8/36 , A61F2/10 , G01N30/72 , A61B17/3205 , A61K8/63 , A61K8/35
CPC分类号： A61F2/10 , A61B17/3205 , A61K8/36 , A61K8/46 , A61K8/492 , A61K8/4926 , A61K31/403 , A61K31/473 , A61K31/506 , A61K31/557 , A61K31/7088 , A61K31/713 , A61K2800/78 , A61K2800/782 , A61Q7/00 , G01N30/7233 , G01N2333/70596 , G01N2500/04 , A61K2300/00
摘要： The invention relates to compositions and methods for regulating hair growth. Specifically, the invention relates to regulating hair growth by regulating the activity one of the prostaglandin D2 (PGD2) receptors, DP-2 (GPR44). Compositions and methods for regulating hair growth include inhibiting hair growth by administering a DP-2 agonist, or stimulating hair growth by administering a DP-2 antagonist.
摘要翻译：本发明涉及用于调节毛发生长的组合物和方法。具体地，本发明涉及通过调节前列腺素D2（PGD2）受体DP-2（GPR44）的活性来调节毛发生长。用于调节毛发生长的组合物和方法包括通过施用DP-2激动剂抑制毛发生长，或通过施用DP-2拮抗剂刺激毛发生长。

10. 发明申请

US20150032129A1 Biological Unit Removal Tools and Methods 有权
标题翻译：生物单位清除工具和方法
公开(公告)号：US20150032129A1
公开(公告)日：2015-01-29
申请号：US14513454
申请日：2014-10-14
申请人： Restoration Robotics, Inc.
发明人： Clifford A. Oostman, JR. , Miguel G. Canales
IPC分类号： A45D26/00 , A61B17/3205
CPC分类号： A45D26/00 , A61B10/0266 , A61B10/0275 , A61B17/32053 , A61B17/32093 , A61B17/322 , A61B2010/0208 , A61B2017/00752 , A61B2017/00969 , A61B2017/320064 , A61B2217/005 , A61B2217/007 , A61F2/10
摘要： Tools and methods are provided for removing biological units from a body surface utilizing a removal tool. The tools may incorporate retention members and mechanisms configured to impede movement of the biological unit in the direction of a distal end of the tool and to improve retention of the biological unit in the tool. Some of the retention members are stationary and some are movable within the lumen of the biological unit removal tools. The distal tips of the tools are desirably configured to reduce the chance of transection of a biological unit, such as by including both cutting segments and blunt relief segments. A number of dual concentric tube embodiments permit a division of removal functions. Distal fluid or gas delivery may be used to help separating biological units from surrounding tissue.
摘要翻译：提供了用于使用去除工具从身体表面去除生物单元的工具和方法。工具可以包括保持构件和机构，其构造成阻止生物单元沿着工具的远端的方向移动，并且改善生物单元在工具中的保留。一些保持构件是固定的，并且一些保持构件可在生物单元去除工具的内腔内移动。工具的远侧末端期望地构造成减少生物单元横切的机会，例如通过包括切割段和钝的释放段。多个双同心管实施例允许除去功能的划分。可以使用远端液体或气体输送来帮助将生物单位与周围组织分离。

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