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1. 发明申请

US20170258862A1 COMPOSITIONS FOR THE TREATMENT OF AGE RELATED DISORDERS 审中-公开
公开(公告)号：US20170258862A1
公开(公告)日：2017-09-14
申请号：US15510391
申请日：2015-09-11
申请人： SWEDISH HERBAL INSTITUTE RESEARCH & DEVELOPMENT AB
发明人： Karl Georg WIKMAN , Alexander PANOSSIAN
IPC分类号： A61K36/41 , A61K36/254 , A61K31/197 , A61K31/7048 , A61K31/7034 , A61K31/09 , A61K31/343 , A61K36/79 , A61K9/48
CPC分类号： A61K36/41 , A61K9/4825 , A61K9/4833 , A61K9/4858 , A61K31/09 , A61K31/197 , A61K31/343 , A61K31/7034 , A61K31/7048 , A61K36/25 , A61K36/254 , A61K36/79 , A61K2236/00 , A61K2236/33 , A61K2236/39 , A61K2236/51 , A61K2300/00
摘要： The invention is directed to compositions for the prophylaxis, treatment and recovery of age related disorders. Compositions comprising a combination of parts of plants or plant extracts belonging to Crassulaceae, Araliaceae and Schisandraceae for the prophylaxis and treatment of age related disorders.

2. 发明授权

US09700589B2 Compositions and methods for improved muscle metabolism 有权
公开(公告)号：US09700589B2
公开(公告)日：2017-07-11
申请号：US14612973
申请日：2015-02-03
申请人： Naturex SA
发明人： Antoine Charles Bily , Marjolaine Meyer , Karl Chevalier , Lise Laurençon , Nicolas Feuillere , Marc Roller , Simona Birtic
IPC分类号： A61K36/00 , A61K36/41 , A61K36/28 , A61K31/575 , A61K31/7028 , A61K9/00
CPC分类号： A61K36/41 , A61K9/0053 , A61K31/575 , A61K31/7028 , A61K36/28
摘要： A composition for improving muscle metabolism in a subject and methods for manufacturing and using same. Embodiments include compositions having an extract of Rhaponticum and an extract of Rhodiola. An extract of Rhaponticum may include amounts of ecdysterones including 20-hydroxyecdysone. An extract of Rhodiola my include salidrosides and rosavins, including rosavin. Suitable ingestion dosages of the composition may be operable to increase protein synthesis and reduce protein proteolysis in a subject.

3. 发明授权

US09629863B2 CDK5 inhibitors and therapeutic uses thereof 有权
公开(公告)号：US09629863B2
公开(公告)日：2017-04-25
申请号：US14586443
申请日：2014-12-30
申请人： The Hong Kong University of Science and Technology
发明人： Nancy Yuk-Yu Ip , Fanny Chui-Fun Ip , Wing Yu Fu , Guangmiao Fu
IPC分类号： A61K31/7048 , A61K31/353 , A61K31/352 , A61K36/41 , A61K31/19 , A61K31/7004 , A61K31/7016 , C07H15/10 , C07D311/62
CPC分类号： A61K31/7048 , A61K31/19 , A61K31/352 , A61K31/353 , A61K31/7004 , A61K31/7016 , A61K36/41 , C07D311/62 , C07H15/10
摘要： Natural occurring inhibitors of cyclin-dependent protein kinase 5 (Cdk5), isolated from the root of Rhodiola rosea are structurally different from the known Cdk inhibitors. They show selectivity among different Cdks and efficacy to inhibit Cdk via a mixed-type of inhibition, which should lead to less toxicity and side-effects. They are useful in preventing and treating diseases and disorders associated with aberrant Cdk5 activities, such as acute and/or chronic pain, neuropathic pain, diabetes mellitus, cancer, neurodegenerative diseases and neuropathological disorders.

4. 发明授权

US09445624B2 Anti-fatigue composition of plant material and preparation method, use and products thereof 有权
标题翻译：植物材料抗疲劳组合物及其制备方法，用途及其产品
公开(公告)号：US09445624B2
公开(公告)日：2016-09-20
申请号：US13814129
申请日：2010-08-05
申请人： Chen Xie , Zhong Zhong
发明人： Chen Xie , Zhong Zhong
IPC分类号： A61K36/185 , A61K36/41 , A61K36/42 , A61K36/81 , A23L2/52 , A23L1/30 , A61K36/424 , A61K36/815
CPC分类号： A23L2/52 , A23L33/105 , A61K36/41 , A61K36/424 , A61K36/815 , A61K2300/00
摘要： The present invention provides a composition of a plant material with anti-fatigue activity, its preparation method, usage and related products. The said composition is manufactured from the following plant materials: 20-80% from the genus Rhodiola; 10-60% Gynostemma; 10-60% Lycium. The said composition can be used to manufacture health product, food or anti-fatigue medicine which is able to significantly reduce the fatigue symptoms of those people suffering from fatigue, improve sleeping quality with no impact on normal body physiology. It is shown that the medicine derived from the present is invention exerts its anti-fatigue effect through improving the functions of erythrocytes and thrombocytes to enhance the body's ability of supplying oxygen. The medicinal composition of the present invention is characterized by the small effective dose and good water solubility and thus suitable to be made into a variety of dosage forms for use.
摘要翻译：本发明提供具有抗疲劳活性的植物材料的组合物，其制备方法，用途及相关产品。所述组合物由以下植物材料制成：来自红景天属的20-80％; 绞股蓝10-60％ 10-60％枸杞子。所述组合物可用于制造健康产品，食品或抗疲劳药物，其能够显着降低患有疲劳的人的疲劳症状，改善睡眠质量，而不影响正常身体生理。表明本发明的药物是通过改善红细胞和血栓细胞的功能而发挥其抗疲劳作用，提高身体供氧的能力。本发明的药物组合物的特征在于有效剂量小，水溶性好，因此适于制成各种使用剂型。

5. 发明申请

US20160166602A1 Food Supplement Composition 审中-公开
标题翻译：食品添加剂组成
公开(公告)号：US20160166602A1
公开(公告)日：2016-06-16
申请号：US14569555
申请日：2014-12-12
申请人： Homeland Housewares, LLC
发明人： Lenny Sands
IPC分类号： A61K31/733 , A61K36/537 , A61K36/82 , A61K36/54 , A61K36/906 , A61K36/9066 , A61K36/81 , A61K36/258 , A61K36/53 , A61K36/41 , A61K36/31 , A61K35/748 , A61K36/899 , A61K36/48 , A61K36/05 , A61K36/87 , A61K36/73 , A61K36/61 , A61K36/07 , A61K36/88 , A61K36/67 , A61K36/064 , A23L1/30 , A61K36/185
CPC分类号： A61K31/733 , A23L33/105 , A23L33/14 , A23V2002/00 , A61K33/14 , A61K35/748 , A61K36/05 , A61K36/064 , A61K36/07 , A61K36/185 , A61K36/21 , A61K36/23 , A61K36/258 , A61K36/31 , A61K36/38 , A61K36/41 , A61K36/45 , A61K36/48 , A61K36/53 , A61K36/537 , A61K36/54 , A61K36/67 , A61K36/73 , A61K36/736 , A61K36/80 , A61K36/81 , A61K36/82 , A61K36/87 , A61K36/8962 , A61K36/899 , A61K36/906 , A61K36/9066 , A61K36/9068 , A61K2300/00 , A23V2200/02 , A23V2200/32 , A23V2200/324
摘要： A dietary supplement for promoting increased vitality, supporting mood, improving heart health, improving immune strength, improving antioxidant balance, protecting against free radical damage, improving bowel function, and enhancing flavonoid intake. The composition is a combination of cacao, chia seeds, green tea, cinnamon, ginger and turmeric in specific percents of the formulation. Other compositions include constituents of inulin, Ashwagandha, green tea, ginseng, Bacopa monnieri, Rhodiola and maca root. Still other compositions include a combination of Spirulina, wheat grass, alfalfa, chlorella and cinnamon powder. Other compositions include constituents of inulin, acerola, grape, beet, current, acai, raspberry, blackberry, pomegranate, lingonberry, mangosteen, and blueberry. Other compositions include maitake mushroom, purple corn, turmeric, cane juice, onion, basil, black pepper, coriander, oregano, rosemary, thyme, parsley, celery seed, bay leaf, tomato, garlic, yeast, salt, carrot, and spinach.
摘要翻译：一种膳食补充剂，用于促进活力增强，配合心情，改善心脏健康，提高免疫力，改善抗氧化平衡，防止自由基损伤，改善肠道功能，增强黄酮摄入。该组合物是制剂中特定百分比的可可，嘉年华，绿茶，肉桂，姜和姜黄的组合。其他组合物包括菊粉，Ashwagandha，绿茶，人参，Bacopa monnieri，Rhodiola和maca根的成分。其他组合物包括螺旋藻，小麦草，苜蓿，小球藻和肉桂粉的组合。其他组合物包括菊粉，黑醋栗，葡萄，甜菜，目前，阿卡，覆盆子，黑莓，石榴，芦荟，山竹果和蓝莓的成分。其他成分包括玉米蘑菇，紫玉米，姜黄，甘蔗汁，洋葱，罗勒，黑胡椒，香菜，牛至，迷迭香，百里香，欧芹，芹菜种子，月桂叶，番茄，大蒜，酵母，盐，胡萝卜和菠菜。

6. 发明授权

US09327004B2 Topical compositions comprising fermented extracts of traditional chinese medicinal (TCM) ingredients, and methods of making and using same 有权
公开(公告)号：US09327004B2
公开(公告)日：2016-05-03
申请号：US14043021
申请日：2013-10-01
申请人： Jing Cheng , Chia-wen Chen , Steven Francis Schnittger , Ming Lu
发明人： Jing Cheng , Chia-wen Chen , Steven Francis Schnittger , Ming Lu
IPC分类号： A61K36/725 , A61K8/97 , A61K8/99 , A61Q19/00 , A61K36/752 , A61K36/756 , A61K36/804 , A61K36/8998 , A61K36/068 , A61K36/074 , A61K36/076 , A61K36/10 , A61K36/16 , A61K36/185 , A61K36/23 , A61K36/235 , A61K36/236 , A61K36/258 , A61K36/28 , A61K36/41 , A61K36/535 , A61K36/539 , A61K36/65 , A61K36/704 , A61K36/06 , A61K36/69
CPC分类号： A61K36/725 , A61K8/97 , A61K8/99 , A61K36/06 , A61K36/068 , A61K36/074 , A61K36/076 , A61K36/10 , A61K36/16 , A61K36/185 , A61K36/23 , A61K36/235 , A61K36/236 , A61K36/258 , A61K36/28 , A61K36/41 , A61K36/535 , A61K36/539 , A61K36/65 , A61K36/69 , A61K36/704 , A61K36/752 , A61K36/756 , A61K36/804 , A61K36/8998 , A61K2800/85 , A61Q19/00
摘要： The present invention relates to topical compositions containing fermented extracts of Traditional Chinese Medicinal (TCM) ingredients for improving the appearance and skin condition of the user. The topical compositions of the present invention are tailored for different users of different skin compositions according to TCM principles. The fermented TCM extracts are characterized by reduced odor and/or color in comparison with unfermented TCM extracts and are therefore more suitable for use in cosmetic products.

7. 发明授权

US09308232B2 Compositions and methods for enhancing brain function 有权
标题翻译：用于增强脑功能的组合和方法
公开(公告)号：US09308232B2
公开(公告)日：2016-04-12
申请号：US14453861
申请日：2014-08-07
申请人： KEYVIEW LABS, INC.
发明人： Josh Reynolds
IPC分类号： A01N43/40 , A01N43/42 , A61K36/41 , A61K31/4748 , A61K31/4375 , A61K36/82 , A61K36/77 , A61K31/455 , A61K31/4415 , A23L1/30 , A23L1/305 , A23L1/308 , A61K45/06 , A61K31/197 , A61K31/205 , A61K31/22 , A61K31/473 , A61K31/164 , A61K31/7034
CPC分类号： A61K36/41 , A23L33/105 , A23L33/15 , A23L33/175 , A23L33/21 , A23V2002/00 , A61K9/0053 , A61K9/28 , A61K31/164 , A61K31/197 , A61K31/205 , A61K31/22 , A61K31/221 , A61K31/223 , A61K31/4375 , A61K31/4415 , A61K31/455 , A61K31/473 , A61K31/4748 , A61K31/475 , A61K31/7028 , A61K31/7034 , A61K36/185 , A61K36/77 , A61K36/82 , A61K45/06 , A61K2300/00 , A23V2200/322 , A23V2250/21 , A23V2250/0612 , A23V2250/705 , A23V2250/7042 , A23V2250/7046
摘要： A nutritional supplement composition enhances cognitive function and includes huperzine A, vinpocetine, acetyl-L-carnitine, and rhodiola. The composition is formulated for oral administration. The huperzine A, vinpocetine, acetyl-L-carnitine, and rhodiola are in a ratio a:b:c:d: respectively such that a as the huperzine A is between about 0.8 and 1.2, b as vinpocetine is between about 80 and 120, c as rhodiola is about 1,600 and 2,400, and d as the acetyl-L-carnitine is between about 8,000 and 12,000.
摘要翻译：营养补充剂组合物增强认知功能，并且包括石杉碱甲，长春西汀，乙酰基-L-肉碱和红景天。将组合物配制成口服给药。石杉碱甲，长春西汀，乙酰基左旋肉碱和红景天分别以a:b:c:d::分别使得如石杉碱甲在约0.8和1.2之间，b是长春西汀在约80和120之间，作为红景天的c约为1,600和2,400，d作为乙酰基-L-肉碱为约8,000至12,000。

8. 发明申请

US20150182572A1 PLANT EXTRACT AND THE PROCESS FOR TREATING HEPATIC FIBROSIS AND LIVER CANCER 有权
标题翻译：植物提取物和治疗肝硬化和肝癌的方法
公开(公告)号：US20150182572A1
公开(公告)日：2015-07-02
申请号：US14144264
申请日：2013-12-30
申请人： DEVELOPMENT CENTER FOR BIOTECHNOLOGY
发明人： Yuh-Shan Chung , Ma-Li Siu , Tzung-Hsien Lai , Szu-Chien Yeh
IPC分类号： A61K36/41
CPC分类号： A61K36/41 , A61K2236/00
摘要： An extract of Graptopetalum paraguayense prepared by a method that includes: extracting a Graptopetalum paraguayense (GP) starting material with an alcoholic solvent to produce an alcoholic extract and a residue; separating the residue from the alcoholic extract; extracting the residue with an aqueous dimethyl sulfoxide (DMSO) solvent to produce a DMSO extract; subjecting the DMSO extract to ultrafiltration using a filter having a selected molecular weight cutoff; drying a fraction retained by the filter to obtain the extract of Graptopetalum paraguayense. Uses of an extract of Graptopetalum paraguayense for the treatment or prevention of liver fibrosis, hepatic cirrhosis, liver cancer, recurrence of liver fibrosis after surgery, or recurrence of liver cancer after surgery.
摘要翻译：通过包括以下方法制备的Graptopetalum巴拉圭的提取物包括：用醇溶剂萃取Graptopetalum巴拉圭（GP）起始原料以产生醇提取物和残余物; 从酒精提取物中分离残留物; 用二甲基亚砜（DMSO）水溶液萃取残余物，得到DMSO提取物; 使用具有选择的分子量截止值的过滤器对DMSO提取物进行超滤; 干燥由过滤器保留的部分，以获得格拉菲叶醋巴拉圭的提取物。 Graptopetalum paraguayense的提取物用于治疗或预防肝纤维化，肝硬化，肝癌，手术后肝纤维化复发或手术后肝癌复发。

9. 发明申请

US20150157672A1 KITS AND METHODS FOR SUSTAINED WEIGHT LOSS 审中-公开
标题翻译：用于持续重量损失的套件和方法
公开(公告)号：US20150157672A1
公开(公告)日：2015-06-11
申请号：US14563764
申请日：2014-12-08
申请人： PHYTOLOGY LABS, INC.
发明人： Brian CAIRNS
IPC分类号： A61K36/03 , A61K36/82 , A61K36/87 , A61K36/77 , A61K31/475 , A61K36/53 , A61K36/73 , A61K36/752 , A61K36/38 , A61K36/48 , A61K36/185
CPC分类号： A61K36/03 , A61K31/405 , A61K31/475 , A61K31/522 , A61K36/185 , A61K36/38 , A61K36/41 , A61K36/48 , A61K36/484 , A61K36/53 , A61K36/63 , A61K36/74 , A61K36/752 , A61K36/81 , A61K36/82 , A61K36/87 , A61K36/88
摘要： Disclosed herein are compositions, methods and kits of effecting and prolonging weight loss by administering weight loss agents for treatment phases of predetermined durations.
摘要翻译：本文公开了通过给予预定持续时间的治疗阶段的减肥剂来影响和延长体重减轻的组合物，方法和试剂盒。

10. 发明授权

US08853170B2 Compositions comprising sugar-cysteine products 有权
标题翻译：包含糖 - 半胱氨酸产物的组合物
公开(公告)号：US08853170B2
公开(公告)日：2014-10-07
申请号：US13015952
申请日：2011-01-28
申请人： David Bagley , Scott Momii , Scott Nagasawa , Herbert T. Nagasawa
发明人： David Bagley , Scott Momii , Scott Nagasawa , Herbert T. Nagasawa
IPC分类号： A61K31/7056 , A61P3/02 , A61P9/10 , A23L1/30 , A23L2/52 , A61K31/198 , A61K31/7004 , A23L1/305 , A23L2/60 , A61K31/7008 , A61K9/00 , A23L1/302 , A61K31/426 , A23L1/304
CPC分类号： A61K31/426 , A23L2/52 , A23L2/60 , A23L33/10 , A23L33/105 , A23L33/15 , A23L33/16 , A23L33/175 , A23V2002/00 , A61K9/0095 , A61K31/122 , A61K31/197 , A61K31/198 , A61K31/30 , A61K31/353 , A61K31/4188 , A61K31/51 , A61K31/519 , A61K31/522 , A61K31/525 , A61K31/675 , A61K31/7004 , A61K31/7008 , A61K31/714 , A61K33/06 , A61K33/24 , A61K36/258 , A61K36/41 , A61K2300/00
摘要： The present invention provides compositions comprising sugar, cysteine, and/or sugar-cysteine products.
摘要翻译：本发明提供了包含糖，半胱氨酸和/或糖 - 半胱氨酸产物的组合物。

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