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1. 发明授权

US09561611B2 Multilayer bioabsorbable scaffolds and methods of fabricating 有权
标题翻译：多层生物可吸收支架及其制造方法
公开(公告)号：US09561611B2
公开(公告)日：2017-02-07
申请号：US14740063
申请日：2015-06-15
申请人： Abbott Cardiovascular Systems Inc.
发明人： Lothar W. Kleiner
IPC分类号： B29C47/06 , B29C47/00 , A61F2/06 , B29C49/04 , B29C47/26 , B29C55/24 , B29C55/04 , B29C49/22 , B32B27/00 , A61L31/06 , A61L31/14 , C08L67/04 , C08L71/02 , B29C47/14 , B29C47/56 , B29C47/70 , B32B27/36 , B29K96/00 , B29L31/00 , A61F2/82 , A61F2/915
CPC分类号： B29C47/0004 , A61F2/06 , A61F2/82 , A61F2002/91566 , A61F2210/0004 , A61F2210/0076 , A61L31/06 , A61L31/148 , B29C47/0009 , B29C47/0023 , B29C47/0054 , B29C47/0057 , B29C47/06 , B29C47/145 , B29C47/26 , B29C47/56 , B29C47/707 , B29C49/04 , B29C49/22 , B29C55/04 , B29C55/24 , B29K2096/00 , B29L2031/7546 , B32B27/00 , B32B27/36 , C08L67/04 , C08L71/02 , Y10T428/1393
摘要： A bioabsorbable scaffold composed of a multilayer structure of alternating layers of different polymers is disclosed. The multilayer structure can have 20 to 1000 layers and the individual thickness of the layers can be 0.2 to 5 microns. A method of making the scaffold including a layer multiplying extrusion process is disclosed.
摘要翻译：公开了由不同聚合物的交替层的多层结构构成的生物可吸收支架。多层结构可以具有20至1000层，并且层的单独厚度可以为0.2至5微米。公开了一种制造包括层叠挤出工艺的支架的方法。

2. 发明申请

US20160122916A1 BRAIDED TEXTILE SLEEVE WITH SELF-SUSTAINING EXPANDED AND CONTRACTED STATES AND METHOD OF CONSTRUCTION THEREOF 审中-公开
标题翻译：具有自主持续扩展和承包状态的BRAIDED TEXTILE SLEEVE及其构造方法
公开(公告)号：US20160122916A1
公开(公告)日：2016-05-05
申请号：US14928107
申请日：2015-10-30
申请人： Federal-Mogul Powertrain, Inc.
发明人： Amel Fathallah , Ana Maria Panea , Zhong Huai Zhang , Jimmy E. Teal , Tianqi Gao , Leigh Krauser
IPC分类号： D04C1/06
CPC分类号： D04C1/06 , B29B11/04 , B29B11/14 , B29C35/02 , B29C55/24 , B29K2101/10 , B29K2105/258 , B29L2023/001 , D04C1/02 , D10B2505/12
摘要： A textile sleeve and method of construction thereof is provided. The sleeve includes a braided, tubular wall extending lengthwise along a central longitudinal axis between opposite ends. The wall has a decreased length, increased cross-sectional area first state and an increased length, decreased cross-sectional area second state. Heat-set, yarns within the wall impart a bias on the wall, wherein the bias causes the wall to remain in each of the first and second states absent an externally applied force.
摘要翻译：提供纺织套筒及其构造方法。套筒包括编织的管状壁，其沿相对端之间的中心纵向轴线纵向延伸。墙壁长度减小，横截面积增加，长度增加，横截面积减小。热定形，壁内的纱线在壁上施加偏压，其中偏置导致壁保持在第一和第二状态中的每一个中，而不存在外部施加的力。

3. 发明申请

US20160059510A1 STRETCH-SLEEVE FILM 审中-公开
标题翻译：拉伸膜片
公开(公告)号：US20160059510A1
公开(公告)日：2016-03-03
申请号：US14781624
申请日：2014-04-15
申请人： DOW GLOBAL TECHNOLOGIES LLC
发明人： Kurt Brunner , Hans Jörg Forster , Thomas Galatik
IPC分类号： B32B1/08 , B32B27/32 , B32B27/08
CPC分类号： B32B1/08 , B29C55/24 , B29C63/18 , B29L2009/00 , B32B1/02 , B32B27/08 , B32B27/32 , B32B33/00 , B32B2270/00 , B32B2307/54 , B32B2307/72 , B32B2323/046 , B32B2439/00
摘要： The present invention concerns a film (1), which contains at least one inner layer (3, 4, 5) and two outer layers (2, 6) enclosing at least one inner layer (3, 4, 5) where the, at least one, inner layer (3, 4, 5) contains a polymer A in a quantity from 70 to 100 wt. %, preferably 80 to 99 wt. % and especially preferably from 90 to 99 wt. %, relative to the total weight of the inner layer (3, 4, 5), which is characterized by special interesting properties, where the outer layers (2, 6) contain a mixture of polymer A and a polymer B, where polymer B is selected from the group consisting of low-density polyethylenes, said film (1) having a thickness from 30 to 70 μm, preferably 35 to 60 μm and especially 40 to 55 and an elastic restoring capacity of more than 95% at an elongation of 55%. The present invention also concerns a process for the production of a film, the use of the wealth. As a stretch-sleeve up film and articles provided with the oil of the invention, such as packaging. The present disclosure is directed to a stretch-sleeve film and articles including the stretch-sleeve film. The stretch-sleeve film includes at least three layers including two skin layers and a core layer. The core layer includes at least 75 wt % of an ethylene/a-olefin copolymer (A) characterized by (i) a density from 0.890 g/cc to 0.920 g/cc; (ii) a Mw/Mn from 2.0 to 4.0; (iii) a ZSVR less than 6.0; and (iv) a CDC from 85 to 150. At least one skin layer includes a polymeric material selected from the ethylene/a-olefin copolymer (A), a low density polyethylene, a medium density polyethylene, and combinations thereof. The stretch-sleeve film has an elastic recovery at 55% stretch of at least 95%.
摘要翻译：本发明涉及一种膜（1），其包含至少一个内层（3,4,5）和两个包围至少一个内层（3,4,5）的外层（2,6），其中，在至少一个，内层（3,4,5）含有70至100重量％的聚合物A。％，优选80〜99wt。％，特别优选为90〜99重量％。相对于内层（3,4,5）的总重量，其特征在于特殊的有趣性质，其中外层（2,6）含有聚合物A和聚合物B的混合物，其中聚合物B 选自低密度聚乙烯，所述膜（1）的厚度为30〜70μm，优选为35〜60μm，特别优选为40〜55，弹性恢复能力在伸长率时大于95％ 55％。本发明还涉及制作薄膜的方法，使用这种财富。作为拉伸套管膜和具有本发明的油的物品，例如包装。本公开涉及拉伸套筒膜和包括拉伸套筒膜的制品。拉伸套筒膜包括至少三层，包括两个表皮层和芯层。芯层包括至少75wt％的乙烯/α-烯烃共聚物（A），其特征在于（i）密度为0.890g / cc至0.920g / cc; （ii）2.0〜4.0的Mw / Mn; （iii）小于6.0的ZSVR; 至少一个表皮层包括选自乙烯/α-烯烃共聚物（A），低密度聚乙烯，中密度聚乙烯及其组合的聚合物材料。拉伸套筒膜在55％拉伸时的弹性回复率至少为95％。

4. 发明申请

US20150273189A1 EXPANDABLE FLUOROPOLYMER DEVICE FOR DELIVERY OF THERAPEUTIC AGENTS AND METHOD OF MAKING 审中-公开
标题翻译：用于输送治疗药物的可扩展的氟聚合物装置和制备方法
公开(公告)号：US20150273189A1
公开(公告)日：2015-10-01
申请号：US14734930
申请日：2015-06-09
申请人： ATRIUM MEDICAL CORPORATION
发明人： Steve A. HERWECK , Peter GINGRAS , Paul MARTAKOS , Theodore KARWOSKI
IPC分类号： A61M25/10
CPC分类号： A61M25/1029 , A61L29/041 , A61M25/10 , A61M2025/0057 , A61M2025/105 , A61M2025/1075 , B29C48/00 , B29C48/09 , B29C55/24 , B29C2049/465 , B29K2027/18 , B29L2022/022 , B29L2031/753 , B32B2305/026 , C08L27/18
摘要： A method of making a radially expandable fluid delivery device includes providing a tube of biocompatible fluoropolymer material with a predetermined porosity based on an extrusion and expansion forming process, applying a radial expansion force to the tube expanding the tube to a predetermined diameter dimension, and removing the radial expansion force. The tube is radially inelastic while sufficiently pliable to be collapsible and inflatable from a collapsed configuration to an expanded configuration upon introduction of an inflation force, such that the expanded configuration occurs upon inflation to the predetermined diameter dimension. The fluid delivery device is constructed of a microporous, biocompatible fluoropolymer material having a microstructure that can provide a controlled, uniform, low-velocity fluid distribution through the walls of the fluid delivery device to effectively deliver fluid to the treatment site without damaging tissue proximate the walls of the device.
摘要翻译：一种制造可径向膨胀的流体递送装置的方法包括：基于挤出和膨胀成形方法提供具有预定孔隙率的生物相容性氟聚合物材料管，向扩管管的管施加径向膨胀力至预定直径尺寸，径向膨胀力。该管是径向无弹性的，同时在引入膨胀力时足够柔软地可从折叠构型膨胀到膨胀构型，使得膨胀构型在膨胀到预定直径尺寸时发生。流体输送装置由具有微结构的微孔生物相容性含氟聚合物材料构成，微结构可以通过流体输送装置的壁提供受控的，均匀的低速流体分配，以有效地将流体输送到治疗部位，而不会损伤邻近的设备的墙壁。

5. 发明申请

US20150157444A1 TAPERED IMPLANTABLE DEVICE AND METHODS FOR MAKING SUCH DEVICES 有权
标题翻译：用于制造这样的装置的带刀片的可植入装置和方法
公开(公告)号：US20150157444A1
公开(公告)日：2015-06-11
申请号：US14557927
申请日：2014-12-02
申请人： W. L. Gore & Associates, Inc.
发明人： Edward H. Cully , Jeffrey B. Duncan , Marc A. Schlaud , Arthur R. Studley, IV
IPC分类号： A61F2/04 , B29C53/08 , A61F2/95
CPC分类号： A61F2/04 , A61F2/06 , A61F2/07 , A61F2/95 , A61F2240/00 , A61F2240/001 , A61F2250/0039 , A61F2250/0058 , B29C53/083 , B29C53/086 , B29C55/005 , B29C55/22 , B29C55/24 , B29C55/30 , B29C57/04 , B29K2027/18 , B29L2031/7534
摘要： A tapered implantable device includes an ePTFE tubular member having a tapered length portion. The tapered length portion provides rapid recovery properties. The tapered length portion can feature a microstructure that includes a multiplicity of bent fibrils.
摘要翻译：锥形可植入装置包括具有锥形长度部分的ePTFE管状构件。锥形长度部分提供快速恢复性能。锥形长度部分可以具有包括多个弯曲原纤维的微结构。

6. 发明申请

US20140107762A1 Biodegradable stent with enhanced fracture toughness 有权
$Biodegradable stent with enhanced fracture toughness$
公开(公告)号：US20140107762A1
公开(公告)日：2014-04-17
申请号：US13998199
申请日：2013-10-09
申请人： Abbott Cardiovascular Systems Inc.
发明人： David C. Gale , Bin Huang , Timothy A. Limon , Vincent J. Gueriguian , Anthony J. Abbate , Klaus Kleine , Stephen Schaible , Jonathan P. Durcan , Thierry Glauser , Bethany Steichen , James Oberhauser , Manish Gada , Lothar Kleiner , Mary Beth Kossuth , Yunbing Wang , Daniel Castro , David Wrolstad
IPC分类号： A61F2/90
CPC分类号： A61F2/90 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61L31/06 , A61L31/14 , B29C35/045 , B29C49/0005 , B29C49/14 , B29C49/4823 , B29C55/24 , B29C69/001 , B29C2049/0089 , B29C2793/0009 , B29K2067/00 , B29K2067/046 , B29K2105/258 , B29K2995/006 , B29L2031/7534 , C08L67/04
摘要： Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.

7. 发明申请

US20140096358A1 DEVICE AND METHOD FOR FIELD XPANSION 有权
标题翻译：用于现场XPANSION的装置和方法
公开(公告)号：US20140096358A1
公开(公告)日：2014-04-10
申请号：US14116298
申请日：2011-07-27
申请人： 3M INNOVATIVE PROPERTIES COMPANY
发明人： Ming Zhang , Jinquan Yang , Zheng Huang , Zhigang Xu , Jiangjiang Ma
IPC分类号： H02G15/18
CPC分类号： H02G15/1826 , B29C55/24 , B29C61/065 , B29C63/18 , B29K2021/00 , H02G15/182 , Y10T29/4987 , Y10T29/53391 , Y10T29/53657
摘要： A device and a method for a field expansion. A support core (30) is inserted into the device by a field expansion apparatus. The field expansion apparatus has a pressure applying means (20) defining a radially expandable inner surface and a flat surface radially outwardly extending from the radially expandable inner surface. The device comprises an elastomeric tubing (10) and an adapter (40). The elastomeric tubing (10) has a forward end opposite a rearward end and an axial bore extending therethrough configured to receive the support core (30). The adapter (40) has a step portion (41) defined by a radial outer surface (42) and a flat surface (43) radially outwardly extending from the radial outer surface (42), and an axial bore (44) extending therethrough. The axial bore (44) has a diameter substantially the same as the diameter of the axial bore (12) of the elastomeric tubing (10). The adapter (40) is positioned substantially coaxially with the elastomeric tubing (10) between the pressure applying means (20) and the elastomeric tubing (10) such that, in response to inserting the support core (30) from the rearward end into the elastomeric tubing (10), the flat surface of the adapter (40) is pushed against the flat surface of the pressure applying means (20) by the elastomeric tubing (10); the interface between a rearward end of the adapter (40) and the forward end of the elastomeric tubing (10) is of high friction so that the adapter (40) and the elastomeric tubing (10) expand radially in unison, and the radial outer surface of the adapter (40) exerts a radially outward pressure against the radially expandable inner surface of the pressure applying means (20). device and method for field expansion device and method for field expansion
摘要翻译：一种用于现场扩展的设备和方法。通过现场扩张装置将支撑芯（30）插入到装置中。场扩展装置具有限定径向可膨胀的内表面的压力施加装置（20）和从径向可膨胀的内表面径向向外延伸的平坦表面。该装置包括弹性管（10）和适配器（40）。弹性体管道（10）具有与后端相对的前端和延伸穿过其构造成接纳支撑芯（30）的轴向孔。适配器（40）具有由径向外表面（42）和从径向外表面（42）径向向外延伸的平坦表面（43）和从其延伸的轴向孔（44）限定的台阶部分（41）。轴向孔（44）具有与弹性管（10）的轴向孔（12）的直径基本相同的直径。适配器（40）与压力施加装置（20）和弹性体管（10）之间的弹性体管（10）基本上同轴地定位，使得响应于从后端将支撑芯（30）插入到弹性管（10），适配器（40）的平坦表面通过弹性管（10）推压到压力施加装置（20）的平坦表面上。适配器（40）的后端与弹性体管道（10）的前端之间的界面具有高摩擦力，使得适配器（40）和弹性体管道（10）一致地径向扩张，并且径向外部适配器（40）的表面对压力施加装置（20）的径向可膨胀的内表面施加径向向外的压力。现场扩容装置及方法及现场扩展方法

8. 发明授权

US08365382B2 Method of forming a clamping ring and a clamping ring 有权
标题翻译：形成夹紧环和夹紧环的方法
公开(公告)号：US08365382B2
公开(公告)日：2013-02-05
申请号：US12667453
申请日：2007-07-02
申请人： Bengt Hedström
发明人： Bengt Hedström
IPC分类号： B23P19/00
CPC分类号： B29C57/00 , B29C55/24 , B29C57/02 , B29C65/66 , B29C65/68 , B29C66/5224 , B29C66/742 , B29D23/001 , B29K2023/06 , B29K2023/0691 , B29K2105/24 , B29K2305/00 , F16L13/14 , F16L47/22 , Y10T24/44 , Y10T24/44983 , Y10T29/49798 , Y10T29/49909 , Y10T29/49911 , Y10T29/49913 , B29C65/00
摘要： A pipe from a plastic material having memory properties is extruded. The extruded pipe is cut to form a pipe part (7). The pipe part (7) is warmed and the end (6b) of the pipe part (7) is bent. The pipe part (7) forms a clamping ring (6) and the bent end (6b) of the pipe part (7) forms a stop edge (10) in the clamping ring (6).
摘要翻译：来自具有记忆性的塑料材料的管材被挤出。将挤压管切割成管部（7）。管部（7）被加热，管部（7）的端部（6b）弯曲。管部（7）形成夹紧环（6），管部（7）的弯曲端（6b）在夹紧环（6）中形成止动边缘（10）。

9. 发明申请

US20120318400A1 Polyvinyl Chloride Formulations 有权
标题翻译：聚氯乙烯配方
公开(公告)号：US20120318400A1
公开(公告)日：2012-12-20
申请号：US13595397
申请日：2012-08-27
申请人： Mark A. Smith , Thomas Marti , Bryan St. Onge , Henri St. Onge
发明人： Mark A. Smith , Thomas Marti , Bryan St. Onge , Henri St. Onge
IPC分类号： C08L27/06 , F16L9/12 , F16L13/02 , C08K13/02 , B32B1/08
CPC分类号： C08L27/06 , B29C55/24 , B29C63/34 , B29C65/02 , B29C65/2015 , B29C65/2061 , B29C65/2092 , B29C65/7841 , B29C65/8215 , B29C65/8246 , B29C66/022 , B29C66/02241 , B29C66/02245 , B29C66/1142 , B29C66/5221 , B29C66/71 , B29C66/90 , B29C66/91411 , B29C66/919 , B29C66/929 , B29C66/949 , B29K2027/06 , B32B1/08 , B32B27/00 , C08K13/02 , F16L9/22 , F16L47/02 , F16L55/1654 , F16L55/1656 , Y10T156/1016 , Y10T156/1043 , Y10T428/1379 , Y10T428/139 , Y10T428/19
摘要： An extrudable polyvinyl chloride composition comprising from 80 to 99.9 percent by weight polyvinyl chloride for use in extruding a first part and a second part, wherein a fusion joint between the first extruded part and the second extruded part is formed by: A) composition at least a portion of a first terminal edge of the first extruded part and a first terminal edge of the second extruded part; B) engaging the melted terminal edges; and C) maintaining pressure between the engaged terminal edges to create a fused joint having a strength that is at least 50% of the tensile strength of the extruded part as measured by ASTM D638-2a. The extruded parts can be pipe sections.
摘要翻译：一种可挤出的聚氯乙烯组合物，其包含80至99.9重量％的用于挤出第一部分和第二部分的聚氯乙烯，其中第一挤出部分和第二挤出部分之间的熔接接头通过以下形成：A）至少组成第一挤出部分的第一端边缘的一部分和第二挤压部分的第一端边缘; B）接合熔化的端边; 和C）保持所接合的端部边缘之间的压力以产生具有通过ASTM D638-2a测量的至少挤出部件的拉伸强度的50％的强度的熔接。挤出的部件可以是管道部分。

10. 发明申请

US20110190872A1 Crush Recoverable Polymer Scaffolds Having a Low Crossing Profile 有权
标题翻译：具有低交叉轮廓的粉碎可回收聚合物支架
公开(公告)号：US20110190872A1
公开(公告)日：2011-08-04
申请号：US13015474
申请日：2011-01-27
申请人： Boris Anukhin , Michael H. Ngo , Mikael Trollsas , Syed Hossainy , John Papp
发明人： Boris Anukhin , Michael H. Ngo , Mikael Trollsas , Syed Hossainy , John Papp
IPC分类号： A61F2/82 , B29C55/24 , B29C69/00
CPC分类号： A61F2/89 , A61F2/82 , A61F2/915 , A61F2002/91508 , A61F2002/91575 , A61F2240/002 , A61M25/1034 , B23P11/005 , B29C55/24 , B29C69/00 , Y10T29/49908
摘要： A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold also has a reduced crimped profile and a modification of the scaffold's ring structure at the crowns that contributes to the reduced crimped profile.
摘要翻译：医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。支架在被气囊部署之后，在支架的直径被挤压或压碎50％后，提供约90％的压碎回收率。支架还具有减小的卷边轮廓和在冠部处的支架环形结构的改进，其有助于减小卷曲轮廓。

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