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    • 3. 发明授权
    • Dendritic polymers with enhanced amplification and interior functionality
    • 具有增强的扩增和内部功能的树枝状聚合物
    • US07985424B2
    • 2011-07-26
    • US11630044
    • 2005-12-21
    • Donald A. TomaliaDouglas R. SwansonBaohua HuangVeera Reddy PulgamJoseph R. HeinzelmannSonke SvensonLori A. ReynaMichael A. ZhuravelAbhay Singh ChauhanCordell R. DeMattei
    • Donald A. TomaliaDouglas R. SwansonBaohua HuangVeera Reddy PulgamJoseph R. HeinzelmannSonke SvensonLori A. ReynaMichael A. ZhuravelAbhay Singh ChauhanCordell R. DeMattei
    • A61K9/14
    • C08G63/46A01N25/10A61K8/85A61K9/0019A61K9/5146A61Q15/00A61Q17/005C08G83/003H01M4/86H01M8/10Y02P70/56
    • Dendritic polymers with enhanced amplification and interior functionality are disclosed. These dendritic polymers are made by use of fast, reactive ring-opening chemistry (or other fast reactions) combined with the use of branch cell reagents in a controlled way to rapidly and precisely build dendritic structures, generation by generation, with cleaner chemistry, often single products, lower excesses of reagents, lower levels of dilution, higher capacity method, more easily scaled to commercial dimensions, new ranges of materials, and lower cost. The dendritic compositions prepared have novel internal functionality, greater stability (e.g., thermal stability and less or no reverse Michael's reaction), and reach encapsulation surface densities at lower generations. Unexpectedly, these reactions of polyfunctional branch cell reagents with polyfunctional cores do not create cross-linked materials. Such dendritic polymers are useful as demulsifiers for oil/water emulsions, wet strength agents in the manufacture of paper, proton scavengers, polymers, nanoscale monomers, calibration standards for electron microscopy, making size selective membranes, and agents for modifying viscosity in aqueous formulations such as paint. When these dendritic polymers have a carried material associated with their surface and/or interior, then these dendritic polymers have additional properties for carrying materials due to the unique characteristics of the dendritic polymer, such as for drug delivery, transfection, and diagnostics.
    • 公开了具有增强的扩增和内部功能的树枝状聚合物。 这些树枝状聚合物通过使用快速,反应性开环化学(或其他快速反应)结合使用分支细胞试剂以受控方式快速和精确地构建树突状结构,一代代,具有更清洁的化学,通常 单一产品,较低的试剂过量,较低的稀释水平,更高的容量方法,更容易缩放到商业尺寸,新的材料范围以及更低的成本。 制备的树枝状组合物具有新颖的内部功能,更高的稳定性(例如,热稳定性和较少的或没有反向的迈克尔反应),并且在较低的代次下达到包封表面密度。 出乎意料的是,多官能分支细胞试剂与多官能核心的这些反应不产生交联材料。 这种树枝状聚合物可用作油/水乳液的破乳剂,纸张制造中的湿强剂,质子清除剂,聚合物,纳米尺寸单体,用于电子显微镜的校准标准品,制备尺寸选择性膜,以及用于在水性制剂中改性粘度的试剂 作为油漆。 当这些树枝状聚合物具有与其表面和/或内部相关的载体材料时,由于树枝状聚合物的独特特征,例如用于药物递送,转染和诊断,这些树枝状聚合物具有携带材料的附加性质。
    • 4. 发明授权
    • Acryl-modified polyester resin composition and method of preparing the same
    • 丙烯酸改性聚酯树脂组合物及其制备方法
    • US07339017B2
    • 2008-03-04
    • US10748577
    • 2003-12-30
    • Ju-Kil LeeDeok-Min Park
    • Ju-Kil LeeDeok-Min Park
    • C08F222/10B05D7/16
    • C08L67/07C08F290/06C08G63/46
    • A condensation polymerization of apolyhydric alcohol and a polybasic acid in a solvent is performed to give a polyester resin. The polyester resin and an unsaturated polybasic acid are polymerized to give a polyester resin intermediate of following formula (1) having a carbon-carbon double bond at one end. The polyester resin intermediate is polymerized with an acryl monomer to give an acryl-modified polyester resin composition. Due to the polymerization of the polyester resin intermediate having the carbon-carbon double bond and the acryl monomer, a paint including the acryl-modified polyester resin composition has advantages of a polyester resin and the acryl resin, R—CH2—O—CO—CH═CH—X  (1) wherein R represents a polyester polymer residue, and X represents a methyl or carboxylic group.
    • 进行多元醇与多元酸在溶剂中的缩聚,得到聚酯树脂。 将聚酯树脂和不饱和多元酸聚合,得到一端具有碳 - 碳双键的下式(1)的聚酯树脂中间体。 聚酯树脂中间体与丙烯酸单体聚合,得到丙烯酸改性的聚酯树脂组合物。 由于具有碳 - 碳双键的聚酯树脂中间体和丙烯酸单体的聚合,包含丙烯酸改性聚酯树脂组合物的涂料具有聚酯树脂和丙烯酸树脂的优点, =“In-line Formulas”end =“lead”?> R-CH 2 -O-CO-CH-CH-X(1)<βin-line-formula description =“In- 线式“end =”tail“?>其中R表示聚酯聚合物残基,X表示甲基或羧基。