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1. 发明授权

US10073156B2 Methods and systems for improved magnetic resonance acquisition 有权
公开(公告)号：US10073156B2
公开(公告)日：2018-09-11
申请号：US14412070
申请日：2013-06-28
申请人： SyntheticMR AB
发明人： Marcel Warntjes
IPC分类号： G01V3/00 , G01R33/50 , G01R33/561 , G01R33/563 , G01R33/56
CPC分类号： G01R33/50 , G01R33/5602 , G01R33/5613 , G01R33/5616 , G01R33/56341
摘要： A magnetic resonance imaging apparatus and method simultaneously measure physical properties including relaxation rates, proton densities, and apparent diffusion coefficients of a subject. The apparatus and method use a single magnetic resonance acquisition of the subject in order to measure the physical properties.

2. 发明申请

US20180136300A1 METHOD AND DEVICE FOR IMAGING BY MAGNETIC RESONANCE 审中-公开
公开(公告)号：US20180136300A1
公开(公告)日：2018-05-17
申请号：US15573340
申请日：2016-05-12
申请人： UNIVERSITE PARIS-SUD , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人： Ludovic Marie Xavier DE ROCHEFORT
IPC分类号： G01R33/58 , G01R33/50 , G01R33/561 , G01R33/563
CPC分类号： G01R33/586 , G01R33/448 , G01R33/50 , G01R33/54 , G01R33/5613 , G01R33/56341
摘要： A MRI device includes: structure applying a main magnetic field on an axis Z over a sample zone; structure emitting a magnetic field gradient and structure emitting a radiofrequency pulse, and a controller. The controller performs on the sample zone, a sequence including: a radiofrequency pulse and/or phase at each repetition; and a spatial gradient of the component along the Z axis. The controller is programmed so that, in the course of repeated applications of the pulse and of the gradient of the sequence of one and the same set: the radio frequency pulse follows, between its repeated applications, a periodic series for its amplitude and for a series U+t=v+i−v; and each repeated application of the gradient of magnetic field of the sequence a, according to a coding spatial direction, a non zero timing integral equal to A and identical for each application of gradient of this set.

3. 发明授权

US09625547B2 Magnetic resonance imaging method for the quantification of the T1 and/or T2 relaxation times in a sample 有权
公开(公告)号：US09625547B2
公开(公告)日：2017-04-18
申请号：US13852239
申请日：2013-03-28
申请人： UNIVERSITATSSPITAL BASEL
发明人： Rahel Heule , Oliver Bieri
IPC分类号： G01V3/00 , G01R33/44 , G01R33/561
CPC分类号： G01R33/448 , G01R33/5613
摘要： A magnetic resonance imaging (MRI) method for the quantification of the longitudinal (T1) and/or transverse (T2) relaxation times in a sample. According to the MRI method, a sample is subjected to an unbalanced steady state free precession (SSFP) sequence comprising a series of consecutive radiofrequency (RF) pulses. By means of the unbalanced SSFP sequence, a first order SSFP FID signal (F1), a lowest order SSFP FID signal (F0), and a lowest order SSFP Echo signal (F−1) are acquired. Based on the F0-signal, the F1-signal and the F−1-signal, the longitudinal (T1) and/or transverse (T2) relaxation times of the sample are determined.

4. 发明授权

US09612301B2 High-throughput and motion insensitive MRI accelerated with multi-echo planar acquisition and related systems 有权
公开(公告)号：US09612301B2
公开(公告)日：2017-04-04
申请号：US13982609
申请日：2012-02-13
申请人： Nan-kuei Chen
发明人： Nan-kuei Chen
IPC分类号： G01R33/32 , G01R33/561
CPC分类号： G01R33/32 , G01R33/5613 , G01R33/5616
摘要： Methods, systems, computer programs, circuits and workstations are configured to generate MRI images using an Echo-Planar Double-Echo Steady State (EP-DESS) pulse sequence and/or a Repeated Imaging with Echo-planar Navigation and Acceleration (RIENA) pulse sequence and image processing protocol to generate clinical MRI images.

5. 发明授权

US09594136B2 Magnetic resonance imaging apparatus and RF pulse control method 有权
标题翻译：磁共振成像装置和RF脉冲控制方法
公开(公告)号：US09594136B2
公开(公告)日：2017-03-14
申请号：US13808659
申请日：2011-06-28
申请人： Kenji Nakanishi , Hiroyuki Itagaki
发明人： Kenji Nakanishi , Hiroyuki Itagaki
IPC分类号： G01R33/54 , G06F17/11 , G01R33/561 , G01R33/565
CPC分类号： G01R33/543 , G01R33/5613 , G01R33/565 , G06F17/11
摘要： Disclosed are a magnetic resonance imaging apparatus and an RF pulse control method wherein an RF pulse sequence in a start-up sequence is set as a monotonically increasing flip angle with offset, in order to reduce ghosts, blurring, and other artifacts during measurement in a transient state. For example, the sum of two adjacent consecutive terms in a monotonically increasing sequence is set as the flip angle. Specifically, the number of RF pulses in the RF pulse sequence and the flip angle for the RF pulses in an SSFP sequence are set, and the monotonically increasing flip angle with offset is found, based on the set number of RF pulses in the RF pulse sequence and the flip angle for the RF pulses in the SSFP sequence, and used as the RF pulse sequence.
摘要翻译：公开了一种磁共振成像装置和RF脉冲控制方法，其中启动序列中的RF脉冲序列被设置为具有偏移的单调增加的翻转角，以便减少在测量期间的重影，模糊和其他伪像暂态例如，将单调递增序列中的两个相邻连续项的和设置为翻转角。具体地，设置RF脉冲序列中的RF脉冲的数量和SSFP序列中的RF脉冲的翻转角，并且基于RF脉冲中的设定的RF脉冲数，找到具有偏移的单调增加的翻转角序列和SSFP序列中RF脉冲的翻转角，并用作RF脉冲序列。

6. 发明授权

US09541624B2 Method and apparatus for magnetic resonance imaging 有权
标题翻译：用于磁共振成像的方法和装置
公开(公告)号：US09541624B2
公开(公告)日：2017-01-10
申请号：US14037619
申请日：2013-09-26
申请人： Cai Xia Fu
发明人： Cai Xia Fu
IPC分类号： G01R33/56 , G01R33/565 , G01R33/561
CPC分类号： G01R33/56527 , G01R33/5607 , G01R33/5613 , G01R33/56509
摘要： In a method and apparatus for magnetic resonance imaging, a flip angle and/or inversion time of a spectrum suppression pulse is calculated according to a steady state condition of a longitudinal magnetization component of a spectrum composition suppressed by the spectrum suppression pulse and a zero crossing point condition of the longitudinal magnetization component. Raw magnetic resonance image data are acquired by applying a magnetic resonance imaging sequence that includes the spectrum suppression pulse provided with the flip angle and/or the inversion time.
摘要翻译：在用于磁共振成像的方法和装置中，根据由频谱抑制脉冲抑制的频谱成分的纵向磁化分量的稳态条件和过零点来计算频谱抑制脉冲的翻转角和/或反转时间纵向磁化分量的点状态。原始磁共振图像数据通过应用包括具有翻转角和/或反转时间的频谱抑制脉冲的磁共振成像序列来获取。

7. 发明授权

US09526423B2 Method for non-contrast enhanced magnetic resonance angiography 有权
公开(公告)号：US09526423B2
公开(公告)日：2016-12-27
申请号：US15164159
申请日：2016-05-25
申请人： GHOST MEDICAL TECHNOLOGIES, LTD
发明人： Robert Edelman
IPC分类号： A61B5/00 , G01R33/563 , G01R33/567 , A61B5/02 , A61B5/0402 , A61B5/055 , G01R33/56 , G01R33/561 , G01R33/565
CPC分类号： A61B5/004 , A61B5/02007 , A61B5/0402 , A61B5/055 , A61B5/7285 , A61B5/7292 , G01R33/5607 , G01R33/5613 , G01R33/5635 , G01R33/56509 , G01R33/5673
摘要： A method for non-contrast enhanced magnetic resonance angiography (“MRA”) that has a short scan time and is insensitive to patient motion is provided. More particularly, the method provides significant arterial conspicuity and substantial venous signal suppression. A two-dimensional single shot acquisition is employed and timed to occur a specific time period after the occurrence of an R-wave in a contemporaneously recorded electrocardiogram. In this manner, k-space data is acquired that is substantially insensitive to variations in arterial flow velocity, or heart rate, and that further substantially suppresses unwanted venous signal in a prescribed imaging slice.

8. 发明申请

US20160262618A1 METHOD FOR NON-CONTRAST ENHANCED MAGNETIC RESONANCE ANGIOGRAPHY 有权
标题翻译：非对比增强磁共振成像方法
公开(公告)号：US20160262618A1
公开(公告)日：2016-09-15
申请号：US15164159
申请日：2016-05-25
申请人： GHOST MEDICAL TECHNOLOGIES, LTD.
发明人： Robert Edelman
IPC分类号： A61B5/00 , A61B5/055
CPC分类号： A61B5/004 , A61B5/02007 , A61B5/0402 , A61B5/055 , A61B5/7285 , A61B5/7292 , G01R33/5607 , G01R33/5613 , G01R33/5635 , G01R33/56509 , G01R33/5673
摘要： A method for non-contrast enhanced magnetic resonance angiography (“MRA”) that has a short scan time and is insensitive to patient motion is provided. More particularly, the method provides significant arterial conspicuity and substantial venous signal suppression. A two-dimensional single shot acquisition is employed and timed to occur a specific time period after the occurrence of an R-wave in a contemporaneously recorded electrocardiogram. In this manner, k-space data is acquired that is substantially insensitive to variations in arterial flow velocity, or heart rate, and that further substantially suppresses unwanted venous signal in a prescribed imaging slice.
摘要翻译：提供了具有短扫描时间并且对患者运动不敏感的非对比度增强磁共振血管造影（“MRA”）的方法。更具体地，该方法提供显着的动脉显着性和显着的静脉信号抑制。采用二维单次采集并定时发生在同时记录的心电图中出现R波之后的特定时间段。以这种方式，获得对动脉血流速度或心率的变化基本上不敏感的k空间数据，并且进一步基本上抑制规定的成像切片中的不希望的静脉信号。

9. 发明申请

US20160139228A1 A MULTI-ECHO LENGTH AND OFFSET VARIED SATURATION (Me-LOVARS) METHOD FOR CHEMICAL EXCHANGE SATURATION TRANSFER (CEST) MR IMAGING 审中-公开
标题翻译：用于化学交换饱和转移（CEST）MR成像的多重长度和偏差饱和度（Me-LOVARS）方法
公开(公告)号：US20160139228A1
公开(公告)日：2016-05-19
申请号：US14895620
申请日：2014-06-03
申请人： KENNEDY KRIEGER INSTITUTE, INC. , THE JOHNS HOPKINS UNIVERSITY
发明人： Michael T. McMahon , Xiaolei Song , Jiadi Xu
IPC分类号： G01R33/561 , G01R33/56 , A61B5/055
CPC分类号： G01R33/5613 , A61B5/0042 , A61B5/055 , G01R33/5601 , G01R33/5605
摘要： The present invention provides a novel approach for CEST MR imaging, called Multi-echo Length and Offset VARied Saturation (Me-LOVARS) CEST. This method allows efficient collection of additional CEST data without penalty in scan time, which could be useful for enhancing the contrast, increasing the specificity or improving quantification of exchange. As CEST-MRI has shown promise at both the pre-clinical and clinical levels, including for detecting and grading brain tumors and evaluating ischemia, using either endogenous CEST contrast or through administration of CEST contrast agents. This fast and robust imaging method is suitable for accelerating image collection and widening the scope of applications for CEST-MRI.
摘要翻译：本发明提供了一种称为多回波长度和偏移饱和饱和度（Me-LOVARS）CEST的CEST MR成像的新方法。这种方法可以有效地收集附加的CEST数据，而不会在扫描时间内造成损失，这可能有助于增强对比度，提高特异性或提高交换量化。由于CEST-MRI在临床前和临床水平上均显示出希望，包括用于检测和分级脑肿瘤并评估局部缺血，使用内源性CEST对比剂或通过施用CEST造影剂。这种快速健壮的成像方法适用于加速图像采集和扩大CEST-MRI的应用范围。

10. 发明授权

US09297870B2 Magnetic resonance examination with instrument detection 有权
标题翻译：磁共振检查与仪器检测
公开(公告)号：US09297870B2
公开(公告)日：2016-03-29
申请号：US13700137
申请日：2011-05-19
申请人： Johan Samuel Van Den Brink
发明人： Johan Samuel Van Den Brink
IPC分类号： G01V3/00 , G01R33/385 , G01R33/28 , G01R33/561 , G01R33/54
CPC分类号： G01R33/3852 , G01R33/285 , G01R33/288 , G01R33/54 , G01R33/5613
摘要： An magnetic resonance examination system for examination of an object comprises an RF system to generate an RF transmission field and gradient system to generate temporary magnet gradient fields. A control module includes a sequence controller to control the RF system and the gradient system to produce acquisition sequences including RF pulses and magnetic gradient pulses to generate magnetic resonance signals. The sequence controller is configured to produce an detection scan including a steady state gradient echo acquisition sequence to generate steady state gradient echo signals and an RF spoiled echo acquisition sequence to produce RF spoiled echo signals. The control module further including an analysis unit to compare the gradient echo signals to the RF spoiled echo signals and for detection of an instrument in the object from the comparison of the gradient echoes and the RF spoiled echoes.
摘要翻译：用于检查物体的磁共振检查系统包括用于产生RF传输场的RF系统和用于产生临时磁体梯度场的梯度系统。控制模块包括用于控制RF系统和梯度系统以产生包括RF脉冲和磁梯度脉冲的采集序列以产生磁共振信号的序列控制器。序列控制器被配置为产生包括稳态梯度回波采集序列的检测扫描，以产生稳态梯度回波信号和RF损坏的回波采集序列以产生RF损坏回波信号。控制模块还包括分析单元，用于将梯度回波信号与RF损坏的回波信号进行比较，并且用于通过梯度回波和RF损坏回波的比较来检测物体中的仪器。

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