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1. 发明申请

US20190247011A1 METHOD FOR IMAGING A SAMPLE WITH BLOOD AND ASSOCIATED DEVICES 审中-公开
公开(公告)号：US20190247011A1
公开(公告)日：2019-08-15
申请号：US16330948
申请日：2017-09-15
申请人： INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS , UNIVERSITE PARIS DIDEROT - PARIS 7 , SORBONNE UNIVERSITÉ
发明人： Zsolt LENKEI , Mathieu PERNOT , Mickael TANTER , Thomas DEFFIEUX
IPC分类号： A61B8/06 , A61B8/08 , A61B8/00
CPC分类号： A61B8/06 , A61B8/085 , A61B8/0891 , A61B8/14 , A61B8/145 , A61B8/4494 , A61B8/488 , A61B8/5207 , G01S7/52077 , G01S15/8925 , G01S15/8927 , G01S15/8981
摘要： The present invention aims at improving the Doppler imaging of a biological sample comprising blood. For this, it is proposed a method for imaging a biological sample (10), the sample (10) comprising blood (14) comprising diffusors and solid tissue (16), the method comprising obtaining observation, each observation being characterized by a different point spread function associating a signal to each location of the region of interest, the signal comprising a first contribution representative of the diffusors of blood vessels within the location, a second contribution representative of the tissue diffusors and a third contribution representative of blood signal associated to blood diffusors outside of the location, and estimating, for each location, the blood flow by using a statistical analysis.

2. 发明申请

US20190231320A1 ULTRASONIC SHEAR WAVE IMAGING WITH BACKGROUND MOTION COMPENSATION 审中-公开
公开(公告)号：US20190231320A1
公开(公告)日：2019-08-01
申请号：US16334792
申请日：2017-09-22
申请人： KONINKLIJKE PHILIPS N.V.
发明人： DAVID WESLEY CLARK
IPC分类号： A61B8/08 , A61B8/14 , A61B8/00
CPC分类号： A61B8/5276 , A61B8/14 , A61B8/4488 , A61B8/463 , A61B8/485 , G01S7/52022 , G01S7/52031 , G01S7/52042 , G01S7/52085 , G01S7/52095 , G01S15/8915 , G01S15/8981
摘要： An ultrasonic diagnostic imaging for analyzing shear wave characteristics utilizes a background motion compensation subsystem which acts as a spatial filter of pulse-to-pulse autocorrelation phases over the ROI of tracking pulse vectors to compensate for background motion. The subsystem is configured to compute the sum of all lag-1 autocorrelations of tracking line ensemble data over the tracking ROI, for each PRI. The inventive technique does not significantly reduce sensitivity to shear waves, because the shear wave is spatially smaller than the ROI.

3. 发明申请

US20170148144A1 SYSTEM FOR OBTAINING 3D IMAGES OF A FLOWING REGION BENEATH AN OBJECT USING SPECKLE REFLECTIONS 审中-公开
公开(公告)号：US20170148144A1
公开(公告)日：2017-05-25
申请号：US15424221
申请日：2017-02-03
申请人： Tessonics Corp.
发明人： Roman Gr. Maev , Jeffrey T. Sadler , Eugene Malyarenko
IPC分类号： G06T5/00 , G06T5/50 , G01S7/52 , G01S15/52 , G01S15/89
CPC分类号： G06T5/002 , A61B8/06 , A61B8/483 , A61B8/5223 , G01F1/66 , G01S7/52026 , G01S7/52028 , G01S15/52 , G01S15/8977 , G01S15/8981 , G01S15/8993 , G06T5/50 , G06T2207/10132 , G06T2207/20224 , G06T2207/30008 , G06T2207/30016 , G06T2207/30104
摘要： A method for imaging a flowing media within static regions includes obtaining a plurality of signals using the speckle properties of the flowing media. The plurality of signals are compared to one another such as by subtraction. The static regions are removed from the plurality of signals by the comparison. The remaining signals are combined (such as by summing) to produce an image of the flowing media.

4. 发明申请

US20160066890A1 Method for Ultrasound Color Doppler Imaging 审中-公开
标题翻译：超声彩色多普勒成像方法
公开(公告)号：US20160066890A1
公开(公告)日：2016-03-10
申请号：US14944759
申请日：2015-11-18
申请人： Texas Instruments Incorporated
发明人： Udayan Dasgupta , David P. Magee , Murtaza Ali
IPC分类号： A61B8/08 , A61B8/06
CPC分类号： G01S15/8981 , A61B8/06 , A61B8/13 , A61B8/461 , A61B8/488 , A61B8/5207 , G01S7/52095 , G01S15/8979
摘要： Methods for color Doppler imaging in an ultrasound imaging system are disclosed herein. Ultrasound radio frequency RF data is demodulated using a nested processing loop including an inner loop and an outer loop. A plurality of Wall filter coefficients are fetched from ultrasound imaging system memory in a single memory access cycle. The plurality Wall filter coefficients are applied to a plurality of complex ultrasound data values in a single execution cycle. The Wall filtered ultrasound data are provided to a flow estimator.
摘要翻译：本文公开了超声成像系统中彩色多普勒成像的方法。使用包括内环和外环的嵌套处理环来解调超声射频RF数据。在单个存储器访问周期中，从超声成像系统存储器中获取多个壁滤波器系数。多个Wall滤波器系数在单个执行周期中被应用于多个复数超声数据值。将经过滤波的超声波数据提供给流量估计器。

5. 发明申请

US20160000398A1 SCANNING TO IDENTIFY AND DELIMIT STATIONARY FLUID POOLS 审中-公开
标题翻译：扫描识别和定位静态流体池
公开(公告)号：US20160000398A1
公开(公告)日：2016-01-07
申请号：US14770287
申请日：2014-02-26
申请人： KONINKLIJKE PHILIPS N.V.
发明人： BALASUNDAR IYYAVU RAJU , AJAY ANAND , JOHN PETRUZZELLO
IPC分类号： A61B8/08 , A61B8/14 , A61B8/06
CPC分类号： A61B8/085 , A61B8/06 , A61B8/14 , A61B8/4427 , A61B8/4488 , A61B8/485 , A61B8/488 , A61B8/5207 , A61B8/5223 , A61B8/5246 , G01S7/52022 , G01S7/52042 , G01S15/8981 , G01S15/8988
摘要： Dynamically identifying a stationary body of fluid (102) within a test volume by scanning within the volume can entail using a first part of a pulse sequence to acoustically interrogate a region within the volume to detect pre-existing movement (124) and, via a separate acoustic interrogation constituting the second part of the pulse sequence, acoustically interrogating the region to distinguish solid from fluid. The scanning is with both interrogations as a unit, so as to span the volume with the interrogations. The body is identified, dynamically based on an outcome of the interrogations. The scanning may span, for the identifying, a current field of view (116), including normal tissue, within an imaging subject. The procedure, from scanning to identifying, may be performed automatically and without need for user intervention, although the user can optionally change the field of view to further search for stationary fluid.
摘要翻译：通过在体积内扫描来动态地识别测试体积内的静止体（102）可能需要使用脉冲序列的第一部分来声学地询问体积内的区域以检测预先存在的运动（124），并且经由单独的声学询问构成脉冲序列的第二部分，以声学方式询问该区域以区分固体和流体。扫描以两个询问为单位，以便在询问时跨越卷。基于询问的结果动态地识别身体。用于识别成像对象内的包括正常组织的当前视野（116）的扫描可以跨越。尽管用户可以可选地改变视场以进一步搜索静止的流体，但是可以自动执行从扫描到识别的过程，而不需要用户干预。

6. 发明授权

US09066679B2 Ultrasonic technique for assessing wall vibrations in stenosed blood vessels 有权
标题翻译：用于评估狭窄血管壁振动的超声技术
公开(公告)号：US09066679B2
公开(公告)日：2015-06-30
申请号：US12815310
申请日：2010-06-14
申请人： Kirk W. Beach , Yongmin Kim , Siddhartha Sikdar
发明人： Kirk W. Beach , Yongmin Kim , Siddhartha Sikdar
IPC分类号： A61B8/00 , A61B8/08 , A61B5/02 , G01S7/52 , G01S15/89 , A61B5/00 , A61B8/06 , A61B8/13
CPC分类号： A61B8/08 , A61B5/02007 , A61B5/7257 , A61B8/06 , A61B8/0816 , A61B8/13 , G01S7/52026 , G01S7/52034 , G01S7/52036 , G01S7/52071 , G01S15/8981
摘要： A real-time signal processing technique for ultrasonic imaging of tissue vibrations for localizing the source of a bruit in a 2D image with respect to the anatomy and/or for obtaining simultaneous information about vibrations and the underlying blood flow. The bruit can be quantitatively assessed using an ensemble of ultrasound echoes. Signal processing enables estimation of wall displacement and the display of time-resolved vibration spectrum. Vibrations are detected and color-coded according to their amplitude and frequency and overlaid on the B-mode and/or color-flow image in real time. Proposed vibration imaging algorithms use data acquired during conventional ultrasonic color-flow imaging and the clutter signal, normally suppressed in color-flow imaging, to detect and characterize tissue vibrations. Three vibration imaging algorithms based on parametric modeling of vibrations and other criteria distinguish between clutter, blood flow, and vibrations. The techniques are usable to detect, locate, image, and quantitatively grade stenoses in blood vessels.
摘要翻译：一种用于组织振动超声成像的实时信号处理技术，用于相对于解剖结构定位二维图像中的血管源，和/或用于获得关于振动和潜在血流的同时信息。可以使用超声回波的整体来定量评估。信号处理使得能够估计壁位移和时间分辨振动谱的显示。根据振幅和频率对振动进行检测和颜色编码，并实时覆盖在B模式和/或彩色流动图像上。建议的振动成像算法使用在常规超声彩色流动成像期间获取的数据和通常在彩色流动成像中抑制的杂波信号来检测和表征组织振动。基于振动参数建模和其他标准的三种振动成像算法区分了杂波，血流和振动。该技术可用于检测，定位，成像和定量评估血管狭窄。

7. 发明授权

US08992429B2 Ultrasonic diagnostic apparatus 有权
标题翻译：超声波诊断仪
公开(公告)号：US08992429B2
公开(公告)日：2015-03-31
申请号：US12023515
申请日：2008-01-31
申请人： Takeshi Sato
发明人： Takeshi Sato
IPC分类号： A61B8/00 , G01S15/89 , G01S7/52 , A61B8/06 , A61B8/13
CPC分类号： G01S15/8981 , A61B8/06 , A61B8/13 , G01S7/52077
摘要： An ultrasonic diagnostic apparatus has an IQ signal acquiring unit, a signal generating unit, a first Doppler signal extracting unit and a second Doppler signal extracting unit. The IQ signal acquiring unit acquires a plurality of groups including an ultrasonic reception IQ signal, under respective interference conditions that differ from one another. The signal generating unit generates an added signal by adding the groups, and to generate an added amplitude signal by adding the amplitudes of the groups. The first Doppler signal extracting unit extracts a first Doppler signal that corresponds to motion from the added signal. The second Doppler signal extracting unit configured to extract a second Doppler signal having a property that differ from the property of the first Doppler signal. At this point, the Doppler signal extracting units are configured so as to extract the Doppler signals respectively while reducing an artifact due to tissue motion.
摘要翻译：超声波诊断装置具有IQ信号获取单元，信号生成单元，第一多普勒信号提取单元和第二多普勒信号提取单元。 IQ信号获取单元在彼此不同的各个干扰条件下获取包括超声波接收IQ信号的多个组。信号生成单元通过相加组生成相加信号，并且通过相加组的幅度来生成相加幅度信号。第一多普勒信号提取单元从相加信号中提取对应于运动的第一多普勒信号。第二多普勒信号提取单元，被配置为提取具有与第一多普勒信号的属性不同的属性的第二多普勒信号。此时，多普勒信号提取单元被配置为分别提取多普勒信号，同时减少由于组织运动引起的伪像。

8. 发明申请

US20140147013A1 DIRECT ECHO PARTICLE IMAGE VELOCIMETRY FLOW VECTOR MAPPING ON ULTRASOUND DICOM IMAGES 审中-公开
标题翻译：直接ECHO颗粒图像速度矢量图在超声DICOM图像上映射
公开(公告)号：US20140147013A1
公开(公告)日：2014-05-29
申请号：US13879006
申请日：2011-10-11
申请人： Robin Shandas , Fuxing Zhang , Jiusheng Chen , Luciano A. Mazzaro
发明人： Robin Shandas , Fuxing Zhang , Jiusheng Chen , Luciano A. Mazzaro
IPC分类号： A61B8/14 , G06T7/00
CPC分类号： A61B8/14 , A61B8/481 , A61B8/5207 , A61B8/5246 , G01S15/8981 , G01S15/8984 , G06T7/0016
摘要： An Echo PIV analysis process, apparatus and algorithm are developed to reduce noise and analyze DICOM images representing a fluid flow of a plurality of particles. A plurality of DICOM images representing sequential image pairs of a plurality of particles is received. The plurality of DICOM sequential image pairs are grouped. The sequential image pairs are correlated to create N cross correlation maps. An average cross-correlation transformation is applied to each cross correlation map to create an image pair vector map for each image pair. A maximizing operation is applied to one or more of the N adjacent image pair vector maps to create a modified image pair vector map for the one or more of the N image pairs. The maps are combined to create a corresponding temporary vector map that are averaged to obtain a mean velocity vector field of the sequential image pairs.
摘要翻译：开发了回波PIV分析过程，装置和算法以减少噪声并分析表示多个粒子的流体流的DICOM图像。接收表示多个粒子的连续图像对的多个DICOM图像。多个DICOM顺序图像对被分组。顺序图像对被相关以产生N个互相关图。将平均互相关变换应用于每个互相关图以为每个图像对创建图像对矢量图。将最大化操作应用于N个相邻图像对矢量图中的一个或多个，以创建N个图像对中的一个或多个的修改图像对矢量图。将地图组合以产生平均以获得顺序图像对的平均速度矢量场的相应临时矢量图。

9. 发明申请

US20130303907A1 Device and System For Imaging and Blood Flow Velocity Measurement 审中-公开
标题翻译：用于成像和血流速度测量的装置和系统
公开(公告)号：US20130303907A1
公开(公告)日：2013-11-14
申请号：US13892108
申请日：2013-05-10
申请人： Volcano Corporation
发明人： Paul Douglas Corl
IPC分类号： A61B8/06 , A61B8/00 , A61B8/12
CPC分类号： A61B8/06 , A61B8/0883 , A61B8/0891 , A61B8/12 , A61B8/4245 , A61B8/445 , A61B8/4461 , A61B8/463 , A61B8/488 , A61B8/5207 , A61B8/5246 , A61B8/5269 , A61B8/543 , G01S15/8981
摘要： Apparatuses, systems, and methods for intravascular ultrasound (IVUS) imaging and blood flow velocity measurement within a vessel using a rotational IVUS catheter are disclosed. The rotational IVUS catheter includes a transducer that is mounted to the catheter at an angle relative to the longitudinal axis of the catheter shaft, such that the imaging surface is substantially nonperpendicular to the angle of the blood flow. The IVUS imaging system includes the rotational IVUS catheter with the tilted transducer, sequencing hardware to generate a series of uniformly spaces transmit pulses and acquisitions per encoder pulse, and signal processing hardware to extract the phase from the ultrasound echo signals for velocity estimation at every pixel of the IVUS image. The system is configured to generate a hybrid IVUS image showing both structural and velocity characteristics of the vessel and the blood therein.
摘要翻译：公开了使用旋转IVUS导管在血管内进行血管内超声（IVUS）成像和血流速度测量的装置，系统和方法。旋转IVUS导管包括以相对于导管轴的纵向轴线成一定角度安装到导管的换能器，使得成像表面基本上不垂直于血流的角度。 IVUS成像系统包括具有倾斜换能器的旋转IVUS导管，测序硬件以产生一系列均匀空间，每个编码器脉冲发射脉冲和采集，以及信号处理硬件，从超声回波信号中提取相位，用于每个像素的速度估计的IVUS图像。该系统被配置为产生显示血管的结构和速度特征以及血液中的血液的混合IVUS图像。

10. 发明申请

US20130094729A1 SINGULAR VALUE FILTER FOR IMAGING OR DETECTION 有权
标题翻译：用于成像或检测的单值过滤器
公开(公告)号：US20130094729A1
公开(公告)日：2013-04-18
申请号：US13650821
申请日：2012-10-12
申请人： F. William Mauldin, JR. , John A, Hossack , Abhay V. Patil
发明人： F. William Mauldin, JR. , John A, Hossack , Abhay V. Patil
IPC分类号： G06K9/40 , B06B1/06
CPC分类号： G06K9/6247 , A61B8/0891 , A61B8/481 , A61B8/485 , A61B8/5207 , G01S7/52039 , G01S7/52041 , G01S7/52042 , G01S7/52046 , G01S15/8915 , G01S15/8981
摘要： Apparatus or techniques can include obtaining information indicative of energy, such as ultrasonic energy, reflected from a tissue region, forming respective input matrices representative of the obtained information, the input matrices respectively comprising an ensemble-of-interest and at least one ensemble corresponding to a spatial location nearby a spatial location corresponding to the ensemble-of-interest, performing respective singular value decompositions on the respective input matrices to obtain respective sets of singular values corresponding to respective sets of singular vectors, obtaining respective output matrices including weighting a respective projection of a respective ensemble-of-interest onto at least one of the singular vectors included in a respective set of singular vectors, and, using the respective output matrices, at least one of determining a characteristic, or constructing an image, of at least a portion of the tissue region.
摘要翻译：设备或技术可以包括获得指示诸如超声波能量的信息的信息，例如从组织区域反射，形成表示所获得信息的相应输入矩阵，输入矩阵分别包括感兴趣集合和至少一个对应于相邻于感兴趣集合的空间位置附近的空间位置，在各个输入矩阵上执行各自的奇异值分解，以获得对应于各组奇异矢量的各组奇异值，获得各自的输出矩阵，包括对相应投影加权将相关的感兴趣整体集合到包含在相应的一组奇异矢量中的奇异矢量中的至少一个，并且使用相应的输出矩阵，确定至少一个部分组织区域。

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