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1. 发明授权

US10005698B2 Fertilizer composition and method for suspending fertilizer in an aqueous solution 有权
公开(公告)号：US10005698B2
公开(公告)日：2018-06-26
申请号：US15147117
申请日：2016-05-05
申请人： BFP Management, LLC
发明人： James Parker Kaiser, II
IPC分类号： C05G3/00 , B01L99/00 , A01C23/00 , A01C23/04 , C05B1/02 , C05B9/00 , C05C1/00 , C05C5/02 , C05C5/04 , C05C9/00 , C05G1/00 , B82Y35/00 , G01N15/10 , B82Y30/00 , G01N15/00 , H01J49/00
CPC分类号： C05G3/007 , A01C23/008 , A01C23/042 , A01C23/047 , B01L1/52 , B01L99/00 , B82Y30/00 , B82Y35/00 , C05B1/02 , C05B9/00 , C05C1/00 , C05C5/02 , C05C5/04 , C05C9/00 , C05G1/00 , C05G3/0005 , G01N15/10 , G01N2015/0038 , H01J49/0027 , Y02P60/214 , Y10S977/773 , Y10S977/775 , Y10S977/88 , Y10S977/902
摘要： A system and method for providing fertilizer for crop production in an aqueous solution comprising nano-sized fertilizer particles, which are free of any chemical side chain and free any micelle to protect the nano-sized particle from re-agglomeration, suspended therein for improved uptake by the population of the crop.

2. 发明授权

US09649381B2 Transporter protein-coupled nanodevices for targeted drug delivery 有权
公开(公告)号：US09649381B2
公开(公告)日：2017-05-16
申请号：US14534994
申请日：2014-11-06
申请人： Wayne State University
发明人： Harry Goshgarian , Guangzhao Mao , Yanhua Zhang
IPC分类号： A61K47/02 , A61K47/48 , A61K31/522 , B82Y5/00
CPC分类号： A61K47/02 , A61K9/1611 , A61K31/522 , A61K47/6415 , A61K47/6923 , B82Y5/00 , Y02A50/465 , Y10S977/775 , Y10S977/906 , Y10T428/2982
摘要： A tripartite nanodevice comprising a targeting portion, a carrier portion, and at least one molecule to be delivered is provided. In particular, a gold nanoparticle linked to a targeting protein and capable of delivering a stimulant for the treatment of respiratory or disease is described. A method of making and a method of using a device of this nature are also described.

3. 发明授权

US09320707B2 Aqueous suspensions of submicron 9-hydroxyrisperidone fatty acid esters 有权
标题翻译：亚微米9-羟基利培酮脂肪酸酯的水悬浮液
公开(公告)号：US09320707B2
公开(公告)日：2016-04-26
申请号：US13538469
申请日：2012-06-29
申请人： Marc Karel Jozef François , Willy Maria Albert Carlo Dries , Esther Dina Guido Basstanie
发明人： Marc Karel Jozef François , Willy Maria Albert Carlo Dries , Esther Dina Guido Basstanie
IPC分类号： A61K31/505 , A01N43/90 , A61K31/519 , A61K9/00 , A61K9/14
CPC分类号： A61K9/0019 , A61K9/145 , A61K9/146 , Y10S977/775 , Y10S977/915 , Y10S977/926
摘要： The present invention is concerned with a pharmaceutical composition suitable as a depot formulation for administration via intramuscular or subcutaneous injection, comprising: (1) as an active ingredient a therapeutically effective amount of a 9-hydroxyrisperidone fatty acid ester or a salt, or a stereoisomer or a stereoisomeric mixture thereof in submicron form and (2) a pharmaceutically acceptable carrier; wherein the pharmaceutically acceptable carrier is water and the active ingredient is suspended therein: and with a process of preparing such a composition. The invention further concerns such a pharmaceutical composition for use as a medicament in the treatment of psychosis, schizophrenia, schizoaffective disorders, non-schizophrenic psychoses, behavioral disturbances associated with neurodegenerative disorders, e.g. in dementia, behavioral disturbances in mental retardation and autism, Tourette's syndrome, bipolar mania, depression, anxiety.
摘要翻译：本发明涉及适合作为通过肌内或皮下注射给药的贮库制剂的药物组合物，其包含：（1）作为活性成分的治疗有效量的9-羟基利培酮脂肪酸酯或其盐或立体异构体或其亚微米形式的立体异构混合物和（2）药学上可接受的载体; 其中药学上可接受的载体是水，并且活性成分悬浮在其中;以及制备这种组合物的方法。本发明还涉及用作治疗精神病，精神分裂症，分裂情感障碍，非精神分裂症性精神病，与神经变性疾病相关的行为障碍的药物组合物。在痴呆症，精神发育迟滞和自闭症行为障碍，图雷特综合征，双相躁狂症，抑郁症，焦虑症。

4. 发明申请

US20150313843A1 SOLID GANAXOLONE COMPOSITIONS AND METHODS FOR THE MAKING AND USE THEREOF 有权
标题翻译：固体GANAXOLONE组合物及其制备和使用方法
公开(公告)号：US20150313843A1
公开(公告)日：2015-11-05
申请号：US14709062
申请日：2015-05-11
申请人： Marinus Pharmaceuticals
发明人： Kenneth SHAW , Mingbao Zhang
IPC分类号： A61K9/10 , A61K31/57
CPC分类号： A61K31/573 , A61K9/0019 , A61K9/10 , A61K9/143 , A61K9/145 , A61K9/146 , A61K9/1676 , A61K9/2054 , A61K9/2059 , A61K9/2077 , A61K9/282 , A61K9/2846 , A61K9/2866 , A61K9/4808 , A61K9/4891 , A61K9/5026 , A61K9/5078 , A61K9/5084 , A61K31/57 , A61K47/02 , A61K47/26 , Y10S977/773 , Y10S977/775 , Y10S977/906 , Y10S977/915
摘要： In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter (D50) of the particles is from about 50 nm to about 500 nm.
摘要翻译：在某些实施方案中，本发明涉及包含稳定的颗粒的组合物，所述稳定颗粒包含加纳西酮，其中颗粒的体积加权中位数直径（D50）为约50nm至约500nm。

5. 发明授权

US09165979B2 Resistive memory 有权
标题翻译：电阻记忆
公开(公告)号：US09165979B2
公开(公告)日：2015-10-20
申请号：US14150654
申请日：2014-01-08
申请人： Bao Tran
发明人： Bao Tran
IPC分类号： H01L45/00 , H01L27/24 , G11C11/21 , B82Y10/00 , G11B9/14 , G11C11/54 , G11C13/02 , G11C13/04 , H01L51/42 , G11C13/00
CPC分类号： G01N33/0034 , B82Y10/00 , B82Y15/00 , B82Y40/00 , G01N27/122 , G01N27/128 , G01N27/4146 , G01N27/4148 , G11B9/14 , G11C11/21 , G11C11/54 , G11C13/0023 , G11C13/004 , G11C13/02 , G11C13/04 , H01L27/2463 , H01L45/12 , H01L45/1233 , H01L45/1253 , H01L45/16 , H01L51/4226 , H01L51/4253 , Y02E10/549 , Y10S977/762 , Y10S977/775 , Y10S977/938 , Y10S977/957
摘要： A memory device includes an upper conductive layer, a lower layer, and a resistive, optical or magnetic matrix positioned between the upper and lower layers.
摘要翻译：存储器件包括位于上层和下层之间的上导电层，下层和电阻式，光学或磁性矩阵。

6. 发明授权

US08986836B2 Microspheres and their methods of preparation 有权
标题翻译：微球及其制备方法
公开(公告)号：US08986836B2
公开(公告)日：2015-03-24
申请号：US12720102
申请日：2010-03-09
申请人： Anima B. Bose , Junbing Yang
发明人： Anima B. Bose , Junbing Yang
IPC分类号： B32B5/18 , H01B1/04 , B82Y30/00 , C01B3/00 , C01B31/02 , C01B31/10 , A61M1/36
CPC分类号： H01B1/04 , A61K9/1611 , A61K47/02 , A61M1/3679 , B01J20/20 , B01J21/02 , B01J21/18 , B01J35/0033 , B01J35/08 , B82Y30/00 , C01B3/0021 , C01B3/0084 , C01B32/05 , C01B32/336 , H01B1/24 , Y02E60/325 , Y10S977/773 , Y10S977/775 , Y10S977/932 , Y10S977/948 , Y10S977/962 , Y10T428/2982 , Y10T428/2989
摘要： Carbon microspheres are doped with boron to enhance the electrical and physical properties of the microspheres. The boron-doped carbon microspheres are formed by a CVD process in which a catalyst, carbon source and boron source are evaporated, heated and deposited onto an inert substrate.
摘要翻译：碳微球掺杂硼以增强微球的电学和物理性能。硼掺杂碳微球通过CVD工艺形成，其中催化剂，碳源和硼源被蒸发，加热并沉积到惰性衬底上。

7. 发明授权

US08932553B2 Method for manufacturing cubic diamond nanocrystals 有权
标题翻译：立方晶体纳米晶体的制造方法
公开(公告)号：US08932553B2
公开(公告)日：2015-01-13
申请号：US13255691
申请日：2010-03-08
申请人： Patrick Curmi , Jean-Paul Boudou , Alain Thorel , Fedor Jelezko , Mohamed Sennour
发明人： Patrick Curmi , Jean-Paul Boudou , Alain Thorel , Fedor Jelezko , Mohamed Sennour
IPC分类号： C01B31/00 , B01J3/06 , B01F3/08 , C01B31/06 , C01B31/14 , C01B31/08 , B01J2/00 , B82Y30/00 , B82Y40/00
CPC分类号： C01B31/0206 , B01J2/00 , B82Y30/00 , B82Y40/00 , C01B32/15 , C01B32/25 , C01B32/28 , C01B32/354 , C01B32/384 , G01N33/582 , Y10S977/773 , Y10S977/775 , Y10T428/2982 , Y10T428/2991 , Y10T436/143333
摘要： A method for manufacturing cubic diamond nanocrystals (10) comprising the following successive steps: (a) providing crystalline diamond powder where the maximum particle size of the powder is equal or more than 2 um and equal or less than 1 mm; (b) milling said crystalline micron diamond powder using nitrogen jet milling micronization so as to manufacture a fine powder; (c) nanomilling the fine powder of step b) using a planetary tungsten carbide ball mill; (d) acid treating the nanomilled powder of step c); (e) extracting the cubic diamond nanocrystals (10) by centrifugation. Advantageously round-shaped cubic diamond nanocrystals are manufactured.
摘要翻译：一种用于制造立方晶体纳米晶体（10）的方法，包括以下连续步骤：（a）提供结晶金刚石粉末，其中粉末的最大粒径等于或大于2um且等于或小于1mm; （b）使用氮喷射微粉化研磨所述结晶微米金刚石粉末，以制造细粉; （c）使用行星式碳化钨球磨机纳米级步骤b）的细粉末; （d）酸处理步骤c）的纳米粉末; （e）通过离心提取立方晶体纳米晶体（10）。有利地制造圆形立方晶体纳米晶体。

8. 发明授权

US08920766B2 Quantum nanostructures, compositions thereof, and methods of making and using same 有权
标题翻译：量子纳米结构，其组合物，及其制造和使用方法
公开(公告)号：US08920766B2
公开(公告)日：2014-12-30
申请号：US13972485
申请日：2013-08-21
申请人： University of Rochester
发明人： Todd D. Krauss , Christopher M. Evans
IPC分类号： B82Y40/00 , C01B17/20 , C01B19/00 , C01B19/04 , C01G11/00 , C01G11/02 , G01N21/64
CPC分类号： G01N21/6486 , B82Y40/00 , C01B19/007 , C01G11/02 , C01P2002/85 , C01P2004/04 , C01P2004/51 , C01P2004/64 , C01P2006/60 , C09K11/565 , Y10S977/70 , Y10S977/773 , Y10S977/774 , Y10S977/775 , Y10S977/813 , Y10S977/824 , Y10S977/825 , Y10S977/927
摘要： Provided are methods for making quantum nanostructures based on use of a combination of nucleation and growth precursors. The methods can be used to provide quantum nanostructures of a selected size. Also provided are quantum nanostructures, compositions comprising the quantum nanostructures, and uses of the quantum nanostructures. The quantum nanostructures can be used, for example, in imaging applications.
摘要翻译：提供了基于使用成核和生长前体的组合制备量子纳米结构的方法。该方法可用于提供所选尺寸的量子纳米结构。还提供了量子纳米结构，包含量子纳米结构的组合物和量子纳米结构的用途。量子纳米结构可用于例如成像应用中。

9. 发明授权

US08894957B2 Method of producing nanophosphor particles 有权
标题翻译：生产纳米荧光粉颗粒的方法
公开(公告)号：US08894957B2
公开(公告)日：2014-11-25
申请号：US12292894
申请日：2008-11-28
申请人： Soon-jae Kwon , Hyun-sik Kim
发明人： Soon-jae Kwon , Hyun-sik Kim
IPC分类号： C01F17/00 , C09K11/77
CPC分类号： C09K11/7797 , C09K11/7712 , Y10S977/775
摘要： Provided is a method of producing spherical nanophosphor particles having a uniform size distribution. When nanophosphor obtained using the method is used in a flat panel display, the flat panel display has higher screen brightness and a higher resolution.
摘要翻译：提供具有均匀尺寸分布的球形纳米荧光体颗粒的制造方法。当使用该方法获得的纳米荧光体用于平板显示器时，平板显示器具有较高的屏幕亮度和更高的分辨率。

10. 发明授权

US08889188B2 Luminescent conducting nano-drug crystal ultra-thin film self-assembly and uses 有权
标题翻译：发光导电纳米药物晶体超薄膜自组装和使用
公开(公告)号：US08889188B2
公开(公告)日：2014-11-18
申请号：US11813265
申请日：2005-12-29
申请人： Yan Fang
发明人： Yan Fang
IPC分类号： A61K9/14 , A61K38/44 , A61K9/51 , A61K31/137 , A61K31/52 , A61K45/06
CPC分类号： A61K38/446 , A61K9/14 , A61K9/51 , A61K31/137 , A61K31/52 , A61K45/06 , Y10S977/775
摘要： This invention involves two fields of photoelectron information materials and pharmaceuticals, especially refers to the self-assembly of conducting photoluminescence nanomedicine crystals and thin films and their preparation processes. In the invention, self-assembling unitary, binary, ternary and quaternary complexes of an antioxidase antioxidant, an agonist of the β-adrenergic receptors, an agonist of the P2-purinergic receptors and an antagonist of benzalkonium-typed calcium channels is to employ an interaction of inelastic electron tunneling, which possesses photoelectron properties of inelastic electron tunneling and photoluminescence with the central wavelength ˜500 nm and the wavelength wide ˜200 nm in the size-controlled square or cubic geometrical complexes. The invention is not only beneficial for drug discovery targeted disease mechanisms, but also profitable for inventions of photoelectron sensing new materials.
摘要翻译：本发明涉及光电子信息材料和药物的两个领域，特别是指导电光致发光纳米医药晶体和薄膜的自组装及其制备方法。在本发明中，抗氧化酶抗氧化剂，β-肾上腺素能受体的激动剂，P2-嘌呤能受体的激动剂和苯扎氯铵型钙通道的拮抗剂的自组装单一，二元，三元和四价复合物是采用非弹性电子隧道的相互作用，其具有在大小控制的正方形或立方几何复合物中具有中心波长〜500nm和波长宽〜200nm的非弹性电子隧道和光致发光的光电子性质。本发明不仅有利于药物发现靶向疾病机制，而且对于光电子感测新材料的发明也是有利的。

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