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1. 发明授权

US11638423B2 Synthetic polymer film whose surface has microbicidal activity, multilayer structure having synthetic polymer film, sterilization method with the use of surface of synthetic polymer film, method for reactivating surface of synthetic polymer film, mold for production of synthetic polymer film, and mold manufacturing method 有权
公开(公告)号：US11638423B2
公开(公告)日：2023-05-02
申请号：US16201609
申请日：2018-11-27
申请人： Sharp Kabushiki Kaisha
发明人： Miho Yamada , Kiyoshi Minoura , Takahiro Nakahara , Seiji Takami
IPC分类号： A01N25/34 , A01N37/02 , A61L9/00 , A01N37/06 , B08B1/00 , B08B3/08 , B08B11/00 , A01N47/10 , A01N61/00 , A61L2/232
摘要： A synthetic polymer film (34A), (34B) having a surface which has a plurality of first raised portions (34Ap), (34Bp), wherein a two-dimensional size of the plurality of first raised portions (34Ap), (34Bp) is in a range of more than 20 nm and less than 500 nm when viewed in a normal direction of the synthetic polymer film (34A), (34B); and the surface has a microbicidal effect.

2. 发明申请

US20230021050A1 COMPOSITIONS AND METHODS OF THEIR USE 有权
公开(公告)号：US20230021050A1
公开(公告)日：2023-01-19
申请号：US17669766
申请日：2022-02-11
申请人： SYNEDGEN, INC.
发明人： Shenda M. Baker , William P. Wiesmann , Stacy Marie Townsend
IPC分类号： A61K31/726 , A61L2/232 , A61K31/722 , A61P1/14 , A61P1/00 , A61K9/00 , A61K47/10
摘要： Provided herein are methods of treating (e.g., inhibiting, modulating, reversing, or reducing the severity of at least one symptom of) a dysbiosis in a subject, the method comprising administering an effective amount of a composition described herein (e.g., a composition comprising polyglucosamine-arginine (PAAG)).

3. 发明申请

US20230011248A1 CELLULOSIC FIBERS COMPRISING INTERNALLY DISPERSED CUPROUS OXIDE NANOPARTICLES 有权
公开(公告)号：US20230011248A1
公开(公告)日：2023-01-12
申请号：US17371906
申请日：2021-07-09
申请人： The United States of America, as represented by the Secretary of Agriculture
发明人： MATTHEW B HILLYER , SUNGHYUN NAM , BRIAN D CONDON
IPC分类号： A01N59/20 , A61L2/232 , A61L9/012 , A01N25/34 , A23B4/20 , A23B4/24 , B65D65/42 , B65D81/28 , D06M11/42
摘要： The invention relates to treated cellulosic fibers comprising internally dispersed cuprous oxide (Cu2O) nanoparticles, methods of preparing such treated cellulosic fibers, and uses of such treated cellulosic fibers.

4. 发明授权

US11518967B2 Chlorine dioxide disinfecting cloth 有权
公开(公告)号：US11518967B2
公开(公告)日：2022-12-06
申请号：US16308152
申请日：2017-06-09
申请人： ALETHIA LIFE SCIENCES AG
发明人： Sebastian Oberwalder
IPC分类号： C11D17/04 , C11D3/48 , C11D3/395 , C11D11/00 , A61L2/232 , A61L2/18 , C11D3/04 , D21H21/36
摘要： The invention relates to highly effective disinfecting or sterilising cloths with chlorine dioxide as the main active ingredient. For this, the chlorine dioxide is only generated shortly before use by bringing a cloth impregnated with a chlorite or chlorate salt in contact with a clearly defined amount of a suitable activation agent that is fluid or dissolved or admixed in a fluid, and prepackaged as a single dose, for the generation of chlorine dioxide. In a preferred embodiment, the impregnated cloth and the activation fluid are packaged in a common packaging unit and the activation occurs by breaking through a barrier separating the cloth or the cloths and the activation fluid. In a further preferred embodiment, the packaging is a moulded part having two packaging spaces separated from one another by removable barriers, which can be converted into a moulded part with only one chamber via simple pressure in one direction. The activation fluid or the disinfecting cloth can contain further substances, such as the pH-value-controlling substances, surfactants, guanidine derivatives, aldehydes, phenoxyethanols, phosphate esters, alcohols, sulfoxides, etc. Preferably, the disinfecting cloth according to the invention is used for disinfecting and/or sterilising medical instruments and/or medical products and/or surfaces.

5. 发明申请

US20220314204A1 TITANIUM DIOXIDE CONTAINING PEROXO TITANIUM COMPLEX AND METHODS OF MANUFACTURING AND APPLICATION OF THE SAME 有权
公开(公告)号：US20220314204A1
公开(公告)日：2022-10-06
申请号：US17587987
申请日：2022-01-28
申请人： TiCoat, Inc.
发明人： Todd W. Hodrinsky , Marcel Janse
IPC分类号： B01J23/72 , B01J35/00 , B01J37/02 , B01J35/02 , A61L2/232 , B01J37/04 , B01J21/06
摘要： A surface coating composition may include titanium dioxide optionally combined with copper oxide to permanently bind to any surface to create a long lasting, self-cleaning, deodorizing, and antimicrobial surface, and preparation method thereof. A method of continuous flow process to create anatase TiO2 crystals with particle sizes ranging from about 0.1 nm to about 200 nm, or further ranging from about 0.1 nm to about 20 nm in size.

6. 发明申请

US20220117105A1 METHOD OF MANUFACTURING ANTIBACTERIAL COVER WINDOW, AND ANTIBACTERIAL COVER WINDOW MANUFACTURED THEREBY 有权
公开(公告)号：US20220117105A1
公开(公告)日：2022-04-14
申请号：US17493470
申请日：2021-10-04
申请人： UTI INC.
发明人： Kukhyun SUNWOO , Tea Joo HA , Jae Suk OH , Jung Cheol NOH
IPC分类号： H05K5/03 , G03F7/00 , G03F7/16 , A61L2/232 , A61L2/238
摘要： Disclosed is a method of manufacturing an antibacterial cover window. The method includes a first step of preparing a substrate, a second step of forming a mask pattern on the substrate through a patterning process, a third step of forming an antibacterial layer on the substrate on which the mask pattern is formed, and a fourth step of removing the mask pattern to obtain an antibacterial pattern formed on the substrate. Through the method, it is possible to produce a cover window with antibacterial patterns regularly and uniformly distributed over the entire area thereof. Thus, the cover window has long-lasting excellent antibacterial property over the entire area thereof.

7. 发明申请

US20220016198A1 METHODS FOR DISRUPTING BIOFILMS 有权
公开(公告)号：US20220016198A1
公开(公告)日：2022-01-20
申请号：US17443445
申请日：2021-07-26
申请人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
发明人： Zvi HAYOUKA
IPC分类号： A61K38/03 , A61K38/16 , A61L2/00 , C08G69/10 , A61K31/785 , B65B55/00 , A61L2/232 , A61P31/04 , A61L2/18
摘要： The present invention provides methods for disrupting biofilms and/or preventing the formation of biofilms along with medical items that contain a coating or covering made of compositions for achieving such disruption or prevention. In particular, the compositions of the present invention provide random-sequence peptide mixtures for use in disrupting bacterial biofilms; the random-sequence peptides having hydrophobic and/or cationic amino acids, wherein the ratio of the total hydrophobic and cationic amino acids in the mixture is predefined.

8. 发明申请

US20210337788A1 POLYMERIC MICELLES CONTAINING AN ESSENTIAL OIL COMPOUND AND A METHOD OF MAKING SAME 有权
公开(公告)号：US20210337788A1
公开(公告)日：2021-11-04
申请号：US17232808
申请日：2021-04-16
申请人： JMO Ideas Inc.
发明人： Barkev Keoshkerian , Francesco Merante , Siyam Subair
IPC分类号： A01N25/34 , A01N65/22 , A01N27/00 , A01N31/08 , B01J13/08 , B01J13/14 , A61L2/232 , D06M16/00
摘要： A method of making an anti-microbial nano-particle containing an essential oil compound (EOC) can include the steps of: a) mixing a quantity of an amphiphilic polymer with a quantity of a solvent to produce a suspension b) heating the suspension to a processing temperature that is higher than a glass transition temperature of the amphiphilic polymer thereby formatting a plurality of polymeric micelles within the solvent, each micelle having a hydrophilic outer portion encasing a hydrophobic core and having a micelle diameter of less than about 80 nm; and c) adding a quantity of an essential oil (EOC) or components of such into the suspension so that a concentration of the essential oil compound is between about 0.2% and about 20% wt, whereby the EOC diffuses into and are encapsulated within the hydrophobic cores of each micelle.

9. 发明授权

US10967086B2 Silver nanoparticle-enhanced photosensitizers as antibiofilm agents 有权
公开(公告)号：US10967086B2
公开(公告)日：2021-04-06
申请号：US16577844
申请日：2019-09-20
申请人： University Of Cincinnati
发明人： Peng Zhang , Rebecca Nogueira e Silva , Hong Tang
IPC分类号： A61L2/232 , A01N57/36 , A61K47/69 , A61K41/00
摘要： The present invention relates generally to compositions and methods of killing biofilm using a surface plasmon coupled to a photosensitizer. A nanostructure (10) may include a silver nanoparticle core (12), a mesoporous silica shell (14), and a photosensitizer (16). A method of killing biofilm may include contacting biofilm with a nanostructure (10) including a silver nanoparticle core (12), a mesoporous silica shell (14), and a photosensitizer (16) to form a blend and exposing the blend to light.

10. 发明申请

US20200376254A1 AUTOMATIC DISINFECTION OF A VASCULAR ACCESS DEVICE CONNECTOR 审中-公开
公开(公告)号：US20200376254A1
公开(公告)日：2020-12-03
申请号：US16878264
申请日：2020-05-19
申请人： Becton, Dickinson and Company
发明人： S. Ray Isaacson , George Mansour , Brian Tanner , He Bai , Lijun Wang , Shaun Staley
IPC分类号： A61M39/16 , A61L2/26 , A61L2/232
摘要： A device to couple a vascular access device to a medical device may include a body, a spring, and a housing. The body may include a distal end, a proximal end, and a lumen extending through the distal end and the proximal end. The proximal end of the body may include a connector. The housing may be coupled to a proximal end of the spring and may enclose the connector. A distal end of the spring may be coupled to the body. The housing may include a flap, which may include an antimicrobial compound. When the housing is disposed in a proximal position, the flap may cover the connector, the antimicrobial compound may contact the connector, and the spring may be uncompressed. In response to movement of the housing from the proximal position to a distal position, the spring may be compressed and the flap may open.

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