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1. 发明授权

US11931809B2 Apparatus for the production of nanoparticles and method for producing nanoparticles 有权
公开(公告)号：US11931809B2
公开(公告)日：2024-03-19
申请号：US16828373
申请日：2020-03-24
申请人： Catalytic Instruments Gmbh & Co. KG
发明人： Adam Meyer Boies , Jacob John Swanson , Hans-Joachim Schulz
IPC分类号： B22F9/08 , B01J2/04 , B01L3/00 , B22F1/054 , B22F9/12 , B82Y40/00
CPC分类号： B22F9/12 , B01J2/04 , B01L3/00 , B01L3/5025 , B01L3/5027 , B22F1/054 , B22F1/056 , B22F9/082 , B22F2009/0832 , B22F2009/0896 , B22F2301/255 , B82Y40/00
摘要： An apparatus for the production of nanoparticles is provided. The apparatus includes a main tube that is closed at a bottom, an inlet channel arranged within the main tube and includes a first opening to the outside of the apparatus and a second opening to the main tube, and a main opening in the main tube. The main tube includes a sample position at the bottom, the cross section of the main tube at the sample position is smaller than at other positions of the main tube, and the second opening of the inlet channel is arranged closer to the sample position than the main opening. Furthermore, an arrangement for the production of nanoparticles and a method for producing nanoparticles are provided.

2. 发明授权

US11884596B2 Method for producing granules for ceramic production 有权
公开(公告)号：US11884596B2
公开(公告)日：2024-01-30
申请号：US17256114
申请日：2019-06-24
申请人： TOKUYAMA CORPORATION
发明人： Hironobu Fujimoto , Tsuyoshi Ikeda
IPC分类号： C04B35/626 , C04B35/581 , B01D1/18 , B01J2/04
CPC分类号： C04B35/62695 , C04B35/581 , C04B35/62625 , B01D1/18 , B01J2/04 , C04B2235/5436
摘要： The present invention aims to provide a method for producing granules for ceramic production, the method having high productivity and making it possible to obtain a ceramic which, when produced by press molding the granules and firing the resulting press molded product, has physical properties kept from lowering. The present invention is characterized by including: a slurry preparation step of preparing a slurry including a mixture containing a powder of an inorganic compound, a binder, and a solvent; a granulation step of introducing the slurry into a spray drying device to form a granulated substance containing the inorganic compound; an exhaust step of exhausting an atmospheric gas within the spray drying device via a cyclone having a surface made of ceramic; and a step of mixing a fine powder, which has been recovered by the cyclone during the exhaust step, with the granulated substance obtained in the granulation step.

3. 发明授权

US11794158B2 Microparticle production process and apparatus 有权
公开(公告)号：US11794158B2
公开(公告)日：2023-10-24
申请号：US17204676
申请日：2021-03-17
申请人： MIDATECH PHARMA (WALES) LIMITED
发明人： Paul Seaman , Huw Jones , Liam McAleer
IPC分类号： B01J2/08 , B01J2/04 , B01J2/18 , B01J2/06
CPC分类号： B01J2/08 , B01J2/04 , B01J2/06 , B01J2/18
摘要： Provided is an apparatus for producing solid polymeric microparticles, the apparatus comprising a plurality of liquid droplet generators for forming liquid droplets of a first liquid, and a nozzle for forming a jet of a second liquid, wherein the plurality of liquid droplet generators and the nozzle are arranged relative to each other such that, in use, liquid droplets from the plurality of liquid droplet generators pass through a gas into said jet of second liquid. Also provided is a process for producing solid microparticles, the process comprising: providing a first liquid comprising a solute and a solvent, the solute comprising a biocompatible polymer, the concentration of polymer in the first liquid being at least 10% w/v, ‘w’ being the weight of the polymer and ‘v’ being the volume of the solvent, providing a plurality of liquid droplet generators operable to generate liquid droplets, providing a jet of a second liquid, causing the plurality of liquid droplet generators to form liquid droplets of the first liquid, passing the liquid droplets through a gas to contact the jet of the second liquid so as to cause the solvent to exit the droplets, thus forming solid microparticles, the solubility of the solvent in the second liquid being at least 5 g of solvent per 100 ml of second liquid, the solvent being substantially miscible with the second liquid.

4. 发明授权

US11794155B2 Mechanical system that fluidizes, mixes, coats, dries, combines, chemically reacts, and segregates materials 有权
公开(公告)号：US11794155B2
公开(公告)日：2023-10-24
申请号：US17464370
申请日：2021-09-01
申请人： Resodyn Corporation
发明人： Peter A. Lucon , Lawrence C. Farrar
IPC分类号： B01F31/24 , B01J2/18 , B01F31/25 , B01J2/00 , B01J2/04 , B01F33/30 , B01F35/90 , B01F35/213 , B01F35/21 , B01F35/221 , B01F35/71 , B01F31/20
CPC分类号： B01F31/25 , B01F31/24 , B01F33/30 , B01F35/213 , B01F35/2115 , B01F35/2213 , B01F35/7179 , B01F35/90 , B01J2/006 , B01J2/04 , B01J2/18 , B01F31/265 , B01F2035/98
摘要： The present application is directed towards systems and methods for adding components to materials being fluidized in a vibratory mixer by use of atomizers or sprayers. A mechanical system can fluidizes, mix, coat, dry, combine, or segregate materials. The system may comprise a vibratory mixer, mixing vessel containing a first material and a sprayer to introduce a second material. The vibratory mixer may generate a fluidized bed of a first material and the sprayer, coupled to the mixing vessel, may introduce a second material onto the fluidized bed to mix the materials in a uniform and even fashion.

5. 发明授权

US11766650B2 System and method to produce particles of organic substances 有权
公开(公告)号：US11766650B2
公开(公告)日：2023-09-26
申请号：US17796189
申请日：2020-11-17
申请人： NANOFORM FINLAND OYJ
发明人： Ilkka Lassila
IPC分类号： B01J2/04 , A61K9/16 , A61K9/51 , B01J3/00 , B01J3/08
CPC分类号： B01J2/04 , A61K9/1682 , A61K9/5192 , B01J3/008 , B01J3/08
摘要： Disclosed are systems and methods for producing particles of organic substances, in particular nanoparticles and microparticles of active pharmaceutical ingredients, wherein the particles are collected in the aid of an extension member engaged to a collection chamber and positioning a nozzle.

6. 发明授权

US11708463B2 Spray drying process for low aspect ratio particles comprising poly[(methyl methacrylate)-co-(methacrylic acid)] 有权
公开(公告)号：US11708463B2
公开(公告)日：2023-07-25
申请号：US17044712
申请日：2019-04-01
申请人： Capsugel Belgium NV
发明人： Kimberly Shepard , Michael Morgen
IPC分类号： C08J3/12 , B01J2/04 , A61K9/16 , C08F220/06 , C08F220/14
CPC分类号： C08J3/122 , B01J2/04 , C08F220/06 , C08F220/14 , A61K9/1635 , A61K9/1682
摘要： Embodiments of a spray-drying process for producing low aspect ratio particles of poly[(methyl methacrylate)-co-(methacrylic acid)] (PMMAMA) are disclosed. In some examples, at least 95% of PMMAMA-containing particles made by the process have an aspect ratio

7. 发明授权

US11634338B1 Process for producing aluminum chlorohydrate particles 有权
公开(公告)号：US11634338B1
公开(公告)日：2023-04-25
申请号：US15455651
申请日：2017-03-10
申请人： USALCO, LLC
发明人： Bruce Wonder
IPC分类号： C01F7/56 , C01F7/57 , B01J2/02 , B01J2/04
摘要： A method of producing particles of aluminum chlorohydrate includes (a) feeding a solution of aluminum chloride through an atomizer associated with a spray dryer, so that a spray of droplets of the solution is formed in the spray dryer, (b) operating the dryer at a temperature sufficient to cause transformation of the droplets into crystal particulates and to dry the crystal particulates, such dried crystal particulates being aluminum chlorohydrate, and (c) recovering the dried crystal particulates. A product produced by the process is also described.

8. 发明申请

US20230077586A1 Microparticle Production Platform, Method of Producing Microparticles and a Pharmaceutical Composition 有权
公开(公告)号：US20230077586A1
公开(公告)日：2023-03-16
申请号：US17801496
申请日：2021-02-25
申请人： Midatech Pharma (Wales) Limited
发明人： Paul Seaman , Connor Davies , Louis King
IPC分类号： B01J2/04 , B01J2/18 , A61K9/16 , A61K38/13 , A61K38/12
摘要： The present invention comprises an apparatus and method for producing a microparticle and pharmaceutical compositions thereof. The apparatus and method rely on continuous inkjet (CIJ) printing to provide high quality microparticles at an improved rate.

9. 发明申请

US20230058525A1 SYSTEM AND METHOD TO PRODUCE PARTICLES OF ORGANIC SUBSTANCES 有权
公开(公告)号：US20230058525A1
公开(公告)日：2023-02-23
申请号：US17796189
申请日：2020-11-17
申请人： NANOFORM FINLAND OYJ
发明人： Ilkka LASSILA
IPC分类号： B01J2/04 , B01J3/08 , A61K9/16 , A61K9/51
摘要： Disclosed are systems and methods for producing particles of organic substances, in particular nanoparticles and microparticles of active pharmaceutical ingredients, wherein the particles are collected in the aid of an extension member engaged to a collection chamber and positioning a nozzle.

10. 发明申请

US20230008121A1 APPARATUSES AND METHODS FOR FORMATION OF PARTICLES 有权
公开(公告)号：US20230008121A1
公开(公告)日：2023-01-12
申请号：US17782368
申请日：2020-12-04
申请人： SIGILON THERAPEUTICS, INC.
发明人： Michael Beauregard , Faith C. David-Hegerich , John Patrick Golden , Joseph Gordon , Erika Ellen Johnston , Robert James Miller , Justin David Morse , Peter Calvin Costello
IPC分类号： G01N1/31 , B01D43/00 , B01J2/04 , B01J13/08
摘要： Described herein are apparatuses and methods for conditioning particles. In some embodiments, the apparatuses and methods are configured for first-in-first-out transit of particles through a chamber containing a conditioning fluid.

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