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1. 发明授权

US11427535B2 Polyanionic delivery of nucleic acids 有权
公开(公告)号：US11427535B2
公开(公告)日：2022-08-30
申请号：US17172640
申请日：2021-02-10
申请人： Translate Bio, Inc.
发明人： Michael Heartlein , Frank DeRosa , Shrirang Karve
IPC分类号： C07C305/06 , C07C317/18 , A61K9/127 , A61K47/20 , A61K47/54 , A61K47/58 , A61K31/7105
摘要： Disclosed are dendritic anionic lipids which are compounds of Formula (I): wherein R and R1 are non-polar groups, L is a linking moiety, and Dm is a dendritic moiety of m generations, each as defined herein. These dendritic anionic lipids are useful for delivery and expression of m RNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.

2. 发明授权

US10961184B2 Polyanionic delivery of nucleic acids 有权
公开(公告)号：US10961184B2
公开(公告)日：2021-03-30
申请号：US16491475
申请日：2018-03-07
申请人： Translate Bio, Inc.
发明人： Michael Heartlein , Frank DeRosa , Shrirang Karve
IPC分类号： C07C305/06 , C07C317/18 , A61K9/127 , A61K47/20 , A61K47/54 , A61K47/58
摘要： Disclosed are dendritic anionic lipids which are compounds of Formula (I): wherein R and R1 are non-polar groups, L is a linking moiety, and Dm is a dendritic moiety of m generations, each as defined herein. These dendritic anionic lipids are useful for delivery and expression of m RNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.

3. 发明授权

US10435619B1 Compounds and method for enhanced oil recovery using sulfur surfactants 有权
公开(公告)号：US10435619B1
公开(公告)日：2019-10-08
申请号：US16448895
申请日：2019-06-21
申请人： INGEVITY SOUTH CAROLINA, LLC
发明人： Kimberley D. Macewan , Reinaldo C. Navarrete , Chao Yang
IPC分类号： C09K8/584 , C11D1/12 , E21B47/00 , E21B43/16 , C07D233/06 , C07C305/06 , C07D209/56 , C07D209/48 , C07D207/40 , C07D233/16
摘要： A method of enhanced oil recovery wherein: (a) a flooding composition is delivered into a subterranean reservoir; (b) the flooding composition includes a sulfur surfactant; and (c) the fluid produced from the subterranean reservoir can also be analyzed to determine if the surfactant is present in the fluid. The surfactant preferably includes a sulfonate moiety or other sulfur-containing moiety. The presence of the surfactant in the fluid produced from the subterranean reservoir is preferably determined by X-ray fluorescence spectroscopy, HPLC-AES, or HPLC-ICP.

4. 发明授权

US10370582B2 Compounds and method for enhanced oil recovery using sulfur surfactants 有权
公开(公告)号：US10370582B2
公开(公告)日：2019-08-06
申请号：US14774568
申请日：2014-03-13
申请人： Ingevity South Carolina, LLC
发明人： Kimberley D. MacEwan , Reinaldo C. Navarrete , Chao Yang
IPC分类号： C09K8/584 , C07D233/16 , C07D207/40 , C07D209/48 , C07D209/56 , C07C305/06 , C07D233/06 , E21B43/16 , E21B47/00
摘要： A method of enhanced oil recovery wherein: (a) a flooding composition is delivered into a subterranean reservoir; (b) the flooding composition includes a sulfur surfactant; and (c) the fluid produced from the subterranean reservoir can also be analyzed to determine if the surfactant is present in the fluid. The surfactant preferably includes a sulfonate moiety or other sulfur-containing moiety. The presence of the surfactant in the fluid produced from the subterranean reservoir is preferably determined by X-ray fluorescence spectroscopy, HPLC-AES, or HPLC-ICP.

5. 发明授权

US09505973B2 Process for producing mineral oil using surfactants based on C16C18-containing alkyl propoxy surfactants 有权
标题翻译：基于含C16C18烷基丙氧基表面活性剂的表面活性剂生产矿物油的方法
公开(公告)号：US09505973B2
公开(公告)日：2016-11-29
申请号：US14069785
申请日：2013-11-01
申请人： Christian Bittner , Günter Oetter , Jack Tinsley , Christian Spindler , Gabriela Alvarez-Juergenson , Sophie Maitro-Vogel , Veronika Wloka , Marcus Guzmann
发明人： Christian Bittner , Günter Oetter , Jack Tinsley , Christian Spindler , Gabriela Alvarez-Juergenson , Sophie Maitro-Vogel , Veronika Wloka , Marcus Guzmann
IPC分类号： C09K8/60 , B01F17/00 , C07C305/06 , C09K8/584
CPC分类号： C09K8/602 , B01F17/0057 , B01F17/0064 , C07C305/06 , C09K8/584
摘要： The invention relates to a process for mineral oil production by means of Winsor Type III microemulsion flooding, in which an aqueous surfactant formulation comprising at least one ionic surfactant of the general formula R1—O—(CH2C(CH3)HO)m(CH2CH2O)n—XY−M+ is injected through injection boreholes into a mineral oil deposit, and crude oil is withdrawn from the deposit through production boreholes. The invention further relates to ionic surfactants of the general formula.
摘要翻译：本发明涉及一种通过Winsor III型微乳液驱油的矿物油生产方法，其中含有至少一种通式为R 1 -O-（CH 2 C（CH 3）HO）m（CH 2 CH 2 O） n-XY-M +通过注射钻孔注入矿物油沉积物中，原油通过生产钻孔从沉积物中排出。本发明还涉及通式的离子表面活性剂。

6. 发明授权

US09346752B2 Permanent attachment of pigments and dyes to surfaces containing Calkyl-OH functionality 有权
标题翻译：将颜料和染料永久性附着到含有C烷基-OH官能团的表面
公开(公告)号：US09346752B2
公开(公告)日：2016-05-24
申请号：US14124035
申请日：2012-07-12
申请人： Jason J. Locklin
发明人： Jason J. Locklin
IPC分类号： C07C317/18 , C07C317/24 , A61K8/46 , A61K8/49 , A61Q5/10 , A61K8/73 , C07C279/18 , C07C305/06 , C07C305/18 , D06P1/62
CPC分类号： C07C317/18 , A61K8/463 , A61K8/49 , A61K8/731 , A61K2800/57 , A61K2800/94 , A61Q5/10 , C07C279/18 , C07C305/06 , C07C305/18 , C07C317/24 , C07D279/18 , D06P1/627 , Y10T442/20
摘要： Embodiment of the present disclosure can include a compound, a structure bonded to the compound, and the like. In an embodiment, the compound can be a linker between an agent and a structure, where the agent can be a dye or a pigment and the structure can be a fiber, hair, or another structure.
摘要翻译：本公开的实施方案可以包括化合物，与化合物结合的结构等。在一个实施方案中，化合物可以是药剂和结构之间的接头，其中药剂可以是染料或颜料，并且结构可以是纤维，毛发或其它结构。

7. 发明申请

US20160024373A1 COMPOUNDS AND METHOD FOR ENHANCED OIL RECOVERY USING SULFUR SURFACTANTS 审中-公开
标题翻译：使用硫磺表面活性剂的增强油回收的化合物和方法
公开(公告)号：US20160024373A1
公开(公告)日：2016-01-28
申请号：US14774568
申请日：2014-03-13
申请人： Ingevity South Caroline, LLC
发明人： Kimberley D. MACEWAN , Reinaldo C. NAVARRETE , Chao YANG
IPC分类号： C09K8/584 , C07C305/06 , E21B47/00 , C07D209/56 , E21B43/16 , C07D233/06 , C07D209/48
CPC分类号： C09K8/584 , C07C305/06 , C07D207/40 , C07D209/48 , C07D209/56 , C07D233/06 , C07D233/16 , E21B43/16 , E21B47/00
摘要： A method of enhanced oil recovery wherein: (a) a flooding composition is delivered into a subterranean reservoir; (b) the flooding composition includes a sulfur surfactant; and (c) the fluid produced from the subterranean reservoir can also be analyzed to determine if the surfactant is present in the fluid. The surfactant preferably includes a sulfonate moiety or other sulfur-containing moiety. The presence of the surfactant in the fluid produced from the subterranean reservoir is preferably determined by X-ray fluorescence spectroscopy, HPLC-AES, or HPLC-ICP.
摘要翻译：一种提高采油的方法，其中：（a）淹水组合物被输送到地下储层中; （b）淹水组合物包含硫表面活性剂; 和（c）也可以分析从地下储层产生的流体，以确定表面活性剂是否存在于流体中。表面活性剂优选包括磺酸盐部分或其它含硫部分。表面活性剂在从地下储层产生的流体中的存在优选通过X射线荧光光谱法，HPLC-AES或HPLC-ICP来确定。

8. 发明申请

US20050245772A1 Derivatives of alcohols and olefins 审中-公开
公开(公告)号：US20050245772A1
公开(公告)日：2005-11-03
申请号：US11116892
申请日：2005-04-28
申请人： Howard Fong , Lizbeth Trevino , Brendan Murray , Manuel Cano , Terry Thomason
发明人： Howard Fong , Lizbeth Trevino , Brendan Murray , Manuel Cano , Terry Thomason
IPC分类号： C07C1/30 , C07C17/10 , C07C27/00 , C07C29/124 , C07C41/01 , C07C43/11 , C07C45/27 , C07C305/06 , C11D1/04 , C11D3/37
CPC分类号： C07C1/30 , C07C29/124 , C07C31/20 , C07C11/02
摘要： Derivatives of branched or linear olefins and alcohols made by halogenation of branched or n-alkanes of the same carbon number, preferably to make primary mono-haloalkanes, which may then be oxidized with metal oxides. The derivatives of primary alcohols of this invention include alcohol ethoxylates, alcohol sulfates, alcohol sulfated ethoxylates, surfactants, including those made with these ethoxylates and/or sulfated ethoxylates, detergents made with these surfactants, oxyalkylated alcohols, oxyalkylated alcohol sulfates, polymethacrylate esters, alkyl amines and their derivatives, linear phthalates, linear adipates, alcohol ether amines, alkyl glycerol ether sulfonates, thioproprionate esters, alkyl polyglucosides, alcohol phosphates, alcohol ether phosphates, esters of fatty acids, alcohol phosphites, and benzophenones. Secondary alcohol derivatives include secondary alcohol ethoxylates, secondary alcohol sulfates, secondary alcohol sulfated ethoxylates, surfactants, including those made with these ethoxylates and/or sulfated ethoxylates, and detergents made with these surfactants. Internal olefins derivatives included within the scope of this invention include alkylbenzene, alkylxylene, detergent alcohols, plasticizer alcohols, alkenyl succinates, ether secondary alcohols, and diols and polyols produced by catalytic dihydroxylation of internal olefins with the use of hydrogen peroxide. Alpha olefin derivatives included within the scope of this invention include internal olefins, alkylbenzene, alkylxylene, alkylphenol, alkylnaphthalene, detergent alcohols, plasticizer alcohols, alkylates of phenylbenzo compounds, alkyl ammonium salts of unsaturated fatty acids, alkyl amines and their derivatives, alpha olefin sulfonates, alkenyl succinates, polyalphaolefins, linear mercaptans, synthetic acids such as based on 1-butene, 1-hexene, or 1-octene, chlorinated alpha olefins, aluminum alkyls, alkyl diphenylether disulfonates, fatty acids, lubricant additives, and ether primary alcohols.

9. 发明授权

US06929896B2 Onium salts and the use therof as latent acids 失效
公开(公告)号：US06929896B2
公开(公告)日：2005-08-16
申请号：US10432263
申请日：2001-11-26
申请人： Hitoshi Yamato , Toshikag Asakura , Akira Matsumoto , Masaki Ohwa
发明人： Hitoshi Yamato , Toshikag Asakura , Akira Matsumoto , Masaki Ohwa
IPC分类号： C07B61/00 , C07C25/00 , C07C25/18 , C07C305/04 , C07C305/06 , C07C305/12 , C07C305/18 , C07C305/20 , C07C305/22 , C07C305/24 , C07C381/12 , C07D309/06 , C07D317/54 , C07D333/16 , C07H9/04 , C08G59/68 , C08G65/10 , G02B5/20 , G03F7/004 , G03F7/039 , H01L21/027 , G03F7/30
CPC分类号： C07H9/04 , B33Y70/00 , C07B2200/11 , C07C25/18 , C07C305/06 , C07C305/20 , C07C305/22 , C07C305/24 , C07C381/12 , C07C2601/14 , C07D309/06 , C07D317/54 , C07D333/16 , C08G59/68 , C08G65/105 , C40B40/00 , G03F7/0045 , G03F7/039 , Y10S430/111 , Y10S430/115 , Y10S430/118 , Y10S430/122 , Y10S430/123
摘要： A chemically amplified photoresist composition comprising, (a) a compound which cures upon the action of an acid or a compound whose solubility is increased upon the action of an acid; and (b) as photosensitive acid donor, at least one compound of the formula Ia, Ib, Ic, IIb or IIc wherein R1 is for example C1-C5alkyl, C3-C30cycloalkyl, C1-C5haloalkyl, C2-C12alkenyl, C4-C8cycloalkenyl, C6-C12bicycloalkenyl, phenyl, naphthyl, anthracyl, phenanthryl, or is a heteroaryl radical; all of which are unsubstituted or substituted; optionally some of the substituents form 5- or 6-membered rings with further substituents on the phenyl, naphthyl, anthracyl, phenanthryl, or heteroaryl ring or with one of the carbon atoms of the phenyl, naphtyl, anthracyl, phenanthryl, or heteroaryl ring; R′1 is for example C1-C12alkylene, C3-C30cycloalkylene, phenylene, naphtylene, diphenylene, or oxydiphenylene, wherein these radicals are unsubstituted or substituted; A and B for example are a direct bond; Ar1 and Ar2 independently of each other for example are phenyl, naphtyl, anthracyl, phenanthryl, or heteroaryl, all of which are unsubstituted or are substituted; Ar3, Ar4 and Ar5 for example have one of the meanings given for Ar1 and Ar2; Y is for example C3-C3-C30cycloalkylene, phenylene, naphthylene, diphenylene, or oxydiphenylene, all of which are unsubstituted or substituted.

10. 发明申请

US20050085547A1 Molecules for inducing differentiation of dendritic cells 审中-公开
标题翻译：用于诱导树突状细胞分化的分子
公开(公告)号：US20050085547A1
公开(公告)日：2005-04-21
申请号：US10748844
申请日：2003-12-31
申请人： Anil Chatterji , Krishnamurthy Natarajan , Venkatasamy Manivel , Kanury Subba Rao , Parameswaran Subrayan , Vinod Singh , Ramasamy Anand , Ehrlich Desa
发明人： Anil Chatterji , Krishnamurthy Natarajan , Venkatasamy Manivel , Kanury Subba Rao , Parameswaran Subrayan , Vinod Singh , Ramasamy Anand , Ehrlich Desa
IPC分类号： A61K31/16 , A61K31/185 , A61K31/19 , A61K31/194 , A61K31/195 , A61K31/255 , C07C305/06 , C07C307/02 , C07C309/17 , C07C309/18
CPC分类号： A61K31/255 , A61K31/16 , A61K31/185 , A61K31/19 , A61K31/194 , A61K31/195 , C07C305/06 , C07C307/02 , C07C309/17 , C07C309/18
摘要： The present invention is related to compounds having general formula Z-OC(CRn1Rn2)—CO-Z wherein Z=OH or NH2 and n1=n2=1 to 8, for modulation of immune response by differentiation dendritic cells consisting novel class of amino acid derivatives (sulfonic acid/sulfate derivatives of naturally occurring amino acids, and their amides) of the general formula ZOC—CR3R4—CR2(NHR1)—COOH, ZOC—CR5R6—CR3R4—C(NHR2)—COOH, ZOC—CR7R8—CR5R6—CR3R4—CR1(NHR2)—COOH wherein Z=OH or NH2; R1 to R8 denotes H, SO3H, or OSO3H. In addition, the dicarboxylic acids and their amides ZOC—(CH2)n—CR1R2—COOH, where Z=OH or NH2; and n=1, 2, 3. The groups R1/R2=H/SO3H or OSO3H or CH2—SO3H or CH2—OSO3H and vice versa. The factors also contain different divalent metal cations such as Mg, Ca and Zn. The composition consists of varying amounts of the above amino acid/dicarboxylic acid derivatives or their pharmaceutically acceptable alkali/alkaline earth metal salts or their salts, the processes for the preparation of the aforesaid compounds useful for the differentiation and maturation of dendritic cells.
摘要翻译：本发明涉及具有通式Z-OC（其中Z = OH或NH 2）的化合物（其中Z = OH或NH 2）并且n1 = n2 = 1至8，用于通过分化树突状细胞调节免疫应答，所述分化树突细胞由通式ZOC-CR的新一类氨基酸衍生物（天然存在的氨基酸的磺酸/硫酸酯衍生物及其酰胺）（NHR 1） - COOH，ZOC-CR 5 > R 6 -CR 3 R 4 -C（NHR 2）-COOH，ZOC-CR _{7 R＆lt; 8＆gt;＆lt; 5＆gt;＆lt; 6＆gt;＆lt; 6＆lt; 3＆lt; 3＆lt; 其中Z = OH或NH 2;其中Z = OH或NH 2;其中Z = OH或NH 2。 R 1至R 8表示H，SO 3 H或OSO 3 H。另外，二羧酸和它们的酰胺ZOC-（CH 2）n -OR 1 R 2 - COOH，其中Z = OH或NH 2; 基团R 1 / R 2 = H / SO 3 H或OSO 3， H或CH 2 -SO 3 H或CH 2 --OSO 3 H，反之亦然。这些因素还含有不同的二价金属阳离子如Mg，Ca和Zn。组合物由不同量的上述氨基酸/二羧酸衍生物或其药学上可接受的碱金属/碱土金属盐或其盐组成，用于制备用于树突状细胞分化和成熟的前述化合物的方法。}

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