专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO2014043220A3 HIV-1 ENVELOPE PROTEINS AND FRAGMENTS THEREOF THAT POSSESS EPITOPES RECOGNIZED BY BROADLY NEUTRALIZING ANTIBODIES 审中-公开
标题翻译： HIV-1包膜蛋白和片段，其通过广泛中和抗体识别出抗原决定簇
公开(公告)号：WO2014043220A3
公开(公告)日：2016-10-27
申请号：PCT/US2013059243
申请日：2013-09-11
申请人： UNIV CALIFORNIA
发明人： BERMAN PHILLIP W , TATSUNO GWEN , YU BIN , MORALES JAVIER , MESA KATHRYN
IPC分类号： A61K39/21 , A61K31/7028 , C07K14/155 , C12N5/10
CPC分类号： A61K39/21 , A61K39/12 , C07K14/005 , C07K14/15 , C07K14/162 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12P21/005
摘要： HIV-1 envelope proteins and fragments that possess naturally occurring and novel engineered epitopes that can be used to elicit (and are recognized by) broadly neutralizing antibodies.
摘要翻译：具有天然存在和新型工程化表位的HIV-1包膜蛋白和片段，其可用于引发（并被广泛中和抗体识别）。

12. 发明申请

WO2016130562A3 METABOLIC ANALYSIS OF THE NUCLEOTIDE DE NOVO AND SALVAGE PATHWAYS 审中-公开
标题翻译：核苷酸代谢和代谢途径的代谢分析
公开(公告)号：WO2016130562A3
公开(公告)日：2016-09-29
申请号：PCT/US2016017172
申请日：2016-02-09
申请人： UNIV CALIFORNIA
发明人： RADU CAIUS , LE THUC
IPC分类号： A61K31/7042 , A61K51/02 , A61K51/04
CPC分类号： C07H19/073 , C07H19/173 , G01N2458/15
摘要： Provided herein are methods for simultaneously detecting an amount of de novo pathway deoxynucleotide triphosphate biosynthesis and an amount of salvage pathway deoxynucleotide triphosphate biosynthesis in a cell. The method includes contacting the cell with labeled de novo and salvage pathway precursors, allowing the cell to metabolize the precursors and identifying the labeled precursors. Also provided are compositions and kits comprising the de novo and salvage pathway precursors.
摘要翻译：本文提供了用于同时检测细胞中的从头路径脱氧核苷酸三磷酸生物合成量和一定量的补救途径脱氧核苷酸三磷酸生物合成的方法。该方法包括使细胞与标记的从头和补救途径前体接触，使细胞代谢前体并鉴定标记的前体。还提供了包含从头和补救途径前体的组合物和试剂盒。

13. 发明申请

WO2016064867A3 OPTICAL INTRAOCULAR SENSOR AND SENSING METHOD 审中-公开
标题翻译：光学眼内传感器和传感方法
公开(公告)号：WO2016064867A3
公开(公告)日：2016-08-25
申请号：PCT/US2015056449
申请日：2015-10-20
申请人： UNIV CALIFORNIA
发明人： PHAN ALEX , TRUONG PHUONG , WEINREB ROBERT N , LASHERAS JUAN , TALKE FRANK
IPC分类号： A61B3/16
CPC分类号： A61B3/16 , A61B3/14
摘要： An optical pressure sensor sized to be implanted at an intraocular location and formed from biocompatible materials. The sensor includes a rigid structure that supports a deformable structure arranged such that deformation of the deformable structure can be monitored optically when implanted in the intraocular location. A method for sensing intraocular pressure images the deformable structure and correlates an optical property affected by the state of deformation of the deformable structure to an intraocular pressure.
摘要翻译：一种光学压力传感器，其尺寸被设计成植入在眼内位置并由生物相容材料形成。该传感器包括刚性结构，该刚性结构支撑可变形结构，该可变形结构被布置成使得当植入眼内位置时可以对可变形结构的变形进行光学监测。一种用于感测眼内压图像的方法，该方法用于将可变形结构的变形状态影响的光学特性与眼内压相关联。

14. 发明申请

WO2015188144A3 FLUORESCENCE METHOD FOR SENSING CHLORINATED DISACCHARIDES 审中-公开
标题翻译：用于感染氯化异黄酮的荧光方法
公开(公告)号：WO2015188144A3
公开(公告)日：2016-03-17
申请号：PCT/US2015034557
申请日：2015-06-05
申请人： UNIV CALIFORNIA
发明人： SINGARAM BAKTHAN , RESENDEZ ANGEL , WEBB DOMINIC-LUC
IPC分类号： G01N21/64
CPC分类号： G01N33/5308 , C07F5/025 , G01N21/6428 , G01N33/582 , G01N2021/6439 , G01N2400/00 , G01N2800/06 , G01N2800/70
摘要： Disclosed are systems for measuring the concentration of a disaccharide in an aqueous medium, the system comprising a boronic acid derivative and a fluorescent molecule. Also disclosed are methods of determining gastrointestinal permeability in a subject, the method comprising contacting an aqueous medium obtained from a subject with the above system to obtain a mixture, where the patient has consumed a known quantity of a disaccharide; measuring the fluorescence emission of the mixture; and correlating the extent of fluorescence emission to the concentration of the disaccharide in the aqueous medium; and correlating the concentration of the disaccharide in the aqueous medium to the gastrointestinal permeability in the subject. Also disclosed are methods of determining the concentration of a disaccharide in an aqueous medium, the method comprising contacting the aqueous medium comprising the disaccharide with the above system to obtain a mixture; measuring the fluorescence emission of the mixture; and correlating the extent of fluorescence emission to the concentration of the disaccharide in the aqueous medium.
摘要翻译：公开了用于测量水性介质中二糖浓度的系统，该系统包含硼酸衍生物和荧光分子。还公开了确定受试者胃肠通透性的方法，所述方法包括将获自受试者的水性培养基与上述系统接触以获得患者已经消耗已知量的二糖的混合物; 测量混合物的荧光发射; 并将荧光发射的程度与水性介质中的二糖的浓度相关联; 并将水性介质中的二糖的浓度与受试者的胃肠通透性相关联。还公开了确定水性介质中二糖浓度的方法，该方法包括使包含二糖的水性介质与上述体系接触以获得混合物; 测量混合物的荧光发射; 并将荧光发射的程度与水性介质中的二糖的浓度相关联。

15. 发明申请

WO2015123154A9 COMBO-HEPATITIS ANTIGEN ASSAYS AND KITS FOR DETECTION OF ACTIVE HEPATITIS VIRUS INFECTIONS 审中-公开
标题翻译：用于检测活动性肝炎病毒感染的抗氧化剂抗原测定和试剂盒
公开(公告)号：WO2015123154A9
公开(公告)日：2016-03-17
申请号：PCT/US2015015092
申请日：2015-02-10
申请人： UNIV CALIFORNIA
发明人： HU KE-QIN
IPC分类号： C12N5/07 , C12Q1/70 , G01N33/53
CPC分类号： G01N33/5767 , C12Q1/707 , C12Q2600/158 , G01N33/54386 , G01N33/5761 , G01N2333/02 , G01N2800/26
摘要： Disclosed herein are assays, systems, and kits for the detection and diagnosis of hepatitis virus infections in subjects.
摘要翻译：本文公开了用于检测和诊断受试者中的肝炎病毒感染的测定，系统和试剂盒。

16. 发明申请

WO2016003626A3 METHOD FOR FABRICATING SUPERCONDUCTING DEVICES USING A FOCUSED ION BEAM 审中-公开
标题翻译：使用聚焦离子束制造超导体器件的方法
公开(公告)号：WO2016003626A3
公开(公告)日：2016-02-25
申请号：PCT/US2015035426
申请日：2015-06-11
申请人： UNIV CALIFORNIA
发明人： CYBART SHANE A , CHO ETHAN Y , DYNES ROBERT C , WONG TRAVIS J
IPC分类号： H01L39/22 , H01L39/24
CPC分类号： H01L39/2496 , H01L27/18 , H01L39/249 , H01L39/2493
摘要： Nano-scale junctions, wires, and junction arrays are created by using a focused high-energy ion beam to direct-write insulating or poorly conducting barriers into thin films of materials that are sensitive to disorder, including superconductors, ferromagnetic materials and semiconductors.
摘要翻译：通过使用聚焦的高能离子束将绝缘或导电不良的阻挡层直接写入对包括超导体，铁磁材料和半导体在内的无序物质的薄膜中，形成纳米级结，导线和接合阵列。

17. 发明申请

WO2015196133A3 ENERGY INFRASTRUCTURE SENSOR DATA RECTIFICATION USING REGRESSION MODELS 审中-公开
标题翻译：能源基础设施传感器数据使用回归模型进行数据恢复
公开(公告)号：WO2015196133A3
公开(公告)日：2016-02-25
申请号：PCT/US2015036779
申请日：2015-06-19
申请人： UNIV CALIFORNIA
发明人： GEORGESCU MICHAEL V , MEZIC IGOR
IPC分类号： G06F15/18
CPC分类号： G06N99/005 , G05B23/0221
摘要： A system and method are provided for physical data rectification using regression models. For example, the physical data may be energy infrastructure sensor data. The system may perform an estimation of sensor data during periods of data dropout using a regression model. The system may assess the accuracy of regression models through the comparison of probability distribution functions of physical data estimated using the regression model and actual physical data.
摘要翻译：提供了使用回归模型进行物理数据整理的系统和方法。例如，物理数据可以是能量基础设施传感器数据。系统可以使用回归模型在数据丢失期间执行传感器数据的估计。该系统可以通过比较使用回归模型估计的物理数据的概率分布函数和实际物理数据来评估回归模型的准确性。

18. 发明申请

WO2015187238A3 ULTRAFAST LIGHT EMITTING DIODES FOR OPTICAL WIRELESS COMMUNICATIONS 审中-公开
标题翻译：用于光纤无线通信的超声发光二极管
公开(公告)号：WO2015187238A3
公开(公告)日：2016-02-18
申请号：PCT/US2015023192
申请日：2015-03-27
申请人： UNIV CALIFORNIA
发明人： LIU ZHAOWEI , LU DANYONG DYLAN
IPC分类号： H01L33/06
CPC分类号： H01L33/0004 , H01L33/005 , H01L33/14 , H01L33/20 , H01L33/24 , H01L51/5048 , H01L51/5056 , H01L51/5209 , H01L51/5225 , H01L2933/0083
摘要： In one aspect, there is provided an apparatus including a light emitting diode. The apparatus may include a plurality of layers including a substrate layer, a buffer layer disposed on the substrate layer, a charge transport layer, a light emission layer, another charge transport layer, and/or a metamaterial layer. The other charge transport layer may have at least one channel etched into the other charge transport layer leaving a residual thickness of the other charge transport layer between a bottom of the etched channel and the light emission layer. A metamaterial layer may be contained in the at least one channel that is proximate to the residual thickness of the charge transport layer. The metamaterial may include a structure including at least one of a dielectric or a metal. The metamaterial may cause the light emitting diode to operate at higher frequencies and with higher efficiency.
摘要翻译：一方面，提供一种包括发光二极管的装置。该装置可以包括多个层，包括衬底层，设置在衬底层上的缓冲层，电荷传输层，发光层，另一电荷传输层和/或超材料层。另一个电荷传输层可以具有蚀刻到另一个电荷传输层中的至少一个沟道，留下在蚀刻沟道的底部和发光层之间的另一个电荷传输层的剩余厚度。超材料层可以包含在接近电荷传输层的剩余厚度的至少一个通道中。超材料可以包括包括电介质或金属中的至少一种的结构。超材料可能导致发光二极管以更高的频率和更高的效率工作。

19. 发明申请

WO2016015009A1 REFLECTANCE BASED PULSE OXIMETRY SYSTEMS AND METHODS 审中-公开
标题翻译：基于反射的脉冲氧化测量系统和方法
公开(公告)号：WO2016015009A1
公开(公告)日：2016-01-28
申请号：PCT/US2015042107
申请日：2015-07-24
申请人： UNIV CALIFORNIA
发明人： ANA ARIAS , CLAIRE LOCHNER , ADRIEN PIERRE , YASSER KHAN
IPC分类号： A61B5/00
CPC分类号： A61B5/14552 , A61B5/0205 , A61B5/024 , A61B5/6815 , A61B5/6826
摘要： Pulse oximeter devices include a first light emitting element that emits red light, a second light emitting element that emits green light or IR light; and a sensor element that detects red and green (or IR) light and that outputs signals representing detected red and green (or IR) light. The pulse oximeter device further includes a flexible substrate, wherein the first light emitting element, the second light emitting element and the sensor element are formed on the flexible substrate. The sensor element is configured to detect the emitted red and green light transmitted through tissue containing blood, and in certain aspects, the sensor element is configured to detect the emitted red and green (or IR) light reflected by tissue containing blood. A signal processing element (e.g., a processor) receives and processes the signals representing detected red and green (or IR) light output by the sensor element to produce signals representing blood oxygenation content.
摘要翻译：脉搏血氧仪装置包括发射红光的第一发光元件，发射绿光或IR光的第二发光元件; 以及检测红色和绿色（或IR）光并且输出表示检测到的红色和绿色（或IR）光的信号的传感器元件。脉搏血氧仪装置还包括柔性基板，其中第一发光元件，第二发光元件和传感器元件形成在柔性基板上。传感器元件被配置为检测透射通过含有血液的组织的发射的红色光和绿色光，并且在某些方面，传感器元件被配置为检测由含有血液的组织反射的红色和绿色（或IR）光。信号处理元件（例如处理器）接收并处理表示由传感器元件输出的检测到的红色和绿色（或IR）光的信号，以产生表示血氧含量的信号。

20. 发明申请

WO2015191859A2 SUTURELESS ANASTOMOSIS DEVICE 审中-公开
标题翻译：无感觉解剖装置
公开(公告)号：WO2015191859A2
公开(公告)日：2015-12-17
申请号：PCT/US2015035343
申请日：2015-06-11
申请人： UNIV CALIFORNIA
发明人： WANG AIJUN , BOUDREAULT DAVID , SITKIN NICOLE , PIVETTI CHRISTOPHER
IPC分类号： A61B17/12
CPC分类号： A61B17/11 , A61B17/00491 , A61B34/73 , A61B2017/00411 , A61B2017/00477 , A61B2017/00876 , A61B2017/1107 , A61B2017/1132
摘要： A sutureless anastomosis device is provided herein comprising an outer tube defining an outer lumen and an inner tube formed of a compliant material defining an inner lumen. The inner tube is disposed within the outer lumen. In various embodiments, the anastomosis device is implanted such that proximal ends of the outer and inner tubes are secured around an outer surface of a proximal blood vessel, the distal end of the outer tube is secured to an outer surface of a distal blood vessel, and the distal end of the inner tube is secured to an inner surface of the distal blood vessel. Such a configuration connects the proximal blood vessel and distal blood vessel together in a manner that limits or eliminates turbulent flow through the anastomosis device. Methods of implantation are also disclosed.
摘要翻译：本文提供了一种无缝合吻合装置，其包括限定外腔的外管和由限定内腔的顺应性材料形成的内管。内管设置在外腔内。在各种实施例中，植入吻合装置，使得外管和内管的近端固定在近端血管的外表面上，外管的远端固定到远端血管的外表面，并且内管的远端固定到远端血管的内表面。这样的构造将近端血管和远端血管连接在一起，以限制或消除穿过吻合装置的湍流。还公开了植入方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式