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1. 发明申请

WO2009033588A3 SELF-CONTROLLED INSULIN DELIVERY SYSTEM 审中-公开
标题翻译：自我控制的胰岛素输送系统
公开(公告)号：WO2009033588A3
公开(公告)日：2010-05-20
申请号：PCT/EP2008007149
申请日：2008-09-02
申请人： HOFFMANN LA ROCHE , BURKHARDT WOLFGANG
发明人： BURKHARDT WOLFGANG
IPC分类号： A61K9/127 , A61K38/28 , A61K47/48
CPC分类号： A61K9/127 , A61K38/28
摘要： The present invention relates to a glucose sensitive vesicle (preferably a multi-lamellar liposome) comprising an insulin-independent glucose transporter integrated into the membrane of the liposome, which further comprises glucokinase, insulin, Mg++ and ATP. Glucose diffuses into the liposome depending on its concentration and will be converted to glucose-6-phosphate. The accumulation of glucose-6-phosphate eventually causes the vesicle to burst. Thus, these liposomes allow an automatic adjustment of insulin levels in a glucose-dependent manner and are, therefore, useful for the treatment of diabetic patients.
摘要翻译：本发明涉及包含整合到脂质体膜中的不依赖胰岛素的葡萄糖转运蛋白的葡萄糖敏感小泡（优选多层脂质体），其还包含葡糖激酶，胰岛素，Mg ++和ATP。葡萄糖根据其浓度扩散到脂质体中，并将转化为葡萄糖-6-磷酸。葡萄糖-6-磷酸的积累最终导致囊泡爆裂。因此，这些脂质体允许以葡萄糖依赖性方式自动调节胰岛素水平，因此可用于治疗糖尿病患者。

2. 发明申请

WO2004107826B1 MULTI FUNCTIONAL TIMEPIECE MODULE WITH APPLICATION SPECIFIC PRINTED CIRCUIT BOARDS 审中-公开
标题翻译：具有应用特定印刷电路板的多功能时序模块
公开(公告)号：WO2004107826B1
公开(公告)日：2005-06-23
申请号：PCT/US2004015347
申请日：2004-05-14
申请人： TIMEX GROUP BV , PLANCON MICHEL G , GALIE LOUIS M , SCHWARTZ HERBERT , STOTZ GERHARD , BURKHARDT WOLFGANG , ZACHMANN HELMUT , BURGHAUSEN ROLAND
发明人： PLANCON MICHEL G , GALIE LOUIS M , SCHWARTZ HERBERT , STOTZ GERHARD , BURKHARDT WOLFGANG , ZACHMANN HELMUT , BURGHAUSEN ROLAND
IPC分类号： G04G9/00 , G04G17/00 , H05K1/00 , H05K1/14 , H05K3/22 , G04C23/02 , G04B37/00
CPC分类号： G04G9/0082 , G04G9/0064 , G04G17/00 , H05K1/0292 , H05K1/141 , H05K3/225
摘要： An electronic device that includes functionality to perform at least two functions, a first of which may be timekeeping and the other of which is at least a function other than the first function. The electronic device comprises a multilayered module comprising a frame having a frame surface; at least two physically separable printed circuit boards, the first of which includes means related to at least the timekeeping and the second of which includes means related to at least the function other than timekeeping, wherein the first printed circuit board is intermediate the frame surface and the second printed circuit board; a battery compartment dimensioned for receiving a battery, wherein the battery compartment is asymmetrically positioned within the module thus creating a region above the first printed circuit board and proximate the battery compartment; and wherein the second printed circuit board is securable within the module and in the region; wherein the functionality of the electronic device can be changed and/or modified by a removal of the second printed circuit board and a replacement with another printed circuit board having means at least in part different from and/or in addition to the means of the second printed circuit board; whereby the first printed circuit board need not be removed to provide for such additional and/or different functionality provided by the replacement printed circuit board.
摘要翻译：一种电子设备，其包括执行至少两个功能的功能，第一功能可以是计时，而另一个功能至少是除了第一功能之外的功能。电子设备包括多层模块，其包括具有框架表面的框架; 至少两个物理上可分离的印刷电路板，其中第一个包括至少与计时相关的装置，其中第二个包括与除了计时以外的功能有关的装置，其中第一印刷电路板位于框架表面之间，第二印刷电路板; 尺寸适于接收电池的电池室，其中所述电池室非对称地定位在所述模块内，从而在所述第一印刷电路板上方并且靠近所述电池室; 并且其中所述第二印刷电路板在所述模块内和所述区域中是可固定的; 其中电子设备的功能性可以通过去除第二印刷电路板而改变和/或修改，并且用另一个印刷电路板进行替换，该印刷电路板至少部分地与第二印刷电路板的装置不同和/ 印刷电路板; 由此第一印刷电路板不需要被去除以提供由替换印刷电路板提供的附加和/或不同的功能。

3. 发明申请

WO2006134158A2 DATE DISPLAY ASSEMBLY FOR AN ELECTRONIC DEVICE 审中-公开
标题翻译：日期显示装置用于电子设备
公开(公告)号：WO2006134158A2
公开(公告)日：2006-12-21
申请号：PCT/EP2006063262
申请日：2006-06-15
申请人： TIMEX GROUP BV , SCHWARTZ HERBERT , BURKHARDT WOLFGANG
发明人： SCHWARTZ HERBERT , BURKHARDT WOLFGANG
IPC分类号： G04C17/00 , G04B19/247
CPC分类号： G04C17/0066 , G04B19/247
摘要： A date display assembly (100) for displaying the day of the month in an electronic device. The assembly comprises a units ring (105) and a tens disc (120), the units ring comprising at least one series of numerals from 0 to 9 and the tens disc comprising a series of numerals from at least 1 to 3 and optionally the numeral 0. The units ring and the tens disc are positioned relative to each other so as to display in the space of a window (122) two numerals side by side, one of which is carried by the units ring (105) and the other of which is carried by the tens disc (120). The units ring is divided into ten sectors or a multiple of ten sectors each separating the numerals 0 to 9, the one sector separating the numerals 9 - 0 having an angular extent equal to 3/4 of the angular extent of the sectors separating the other numerals. In the preferred embodiment, the device is a timepiece and a wristwatch in particular.
摘要翻译：一种用于在电子设备中显示月份的日期的日期显示组件（100）。组件包括单元环（105）和十位盘（120），所述单元环包括至少一个从0到9的一系列数字，并且所述十位盘包括至少1至3的一系列数字，并且可选地包括数字单元环和十位盘相对于彼此定位，以便在窗口（122）的空间中并列显示两个数字，其中一个由单元环（105）承载，另一个由单元环其由数十个盘（120）承载。单元环被分成十个扇区或十个扇区的倍数，每个扇区分隔数字0到9，一个扇区分隔数字9-0的角度范围等于扇区分隔另一个的角度范围的3/4 数字。在优选实施例中，该装置特别是钟表和手表。

4. 发明申请

WO2006134156A2 DATE DISPLAY ASSEMBLY FOR A TIMEPIECE 审中-公开
标题翻译：日期显示总成为时间表
公开(公告)号：WO2006134156A2
公开(公告)日：2006-12-21
申请号：PCT/EP2006/063259
申请日：2006-06-15
申请人： TIMEX GROUP B.V. , SCHWARTZ, Herbert , BURKHARDT, Wolfgang
发明人： SCHWARTZ, Herbert , BURKHARDT, Wolfgang
IPC分类号： G04C17/00 , G04B19/24
CPC分类号： G04B19/247 , G04C17/0058 , G04C17/0066
摘要： A date display assembly for an electronic device, the assembly comprising a ones date ring assembly (21), a tens date disc assembly (6) and a gear assembly (7B) comprising a four-legged blocking star (12) and a four-legged driving star (11). The driving star (11) is used for driving the tens disc (6) and the blocking star (12) is used to maintain the proper orientation of the tens disc.
摘要翻译：一种用于电子设备的日期显示组件，该组件包括一个日期环组件（21），一个十位日期盘组件（6）和一个包括四腿阻塞星（12）和四脚架组件（8）的齿轮组件（7B）有腿的驾驶明星（11）。驱动星（11）用于驱动十位盘（6），并且阻挡星（12）用于保持十位盘的正确取向。

5. 发明申请

WO2005052698A3 PERPETUAL CALENDAR FOR A TIMEPIECE 审中-公开
标题翻译：时间表的PERPETUAL CALENDAR
公开(公告)号：WO2005052698A3
公开(公告)日：2005-10-20
申请号：PCT/US2004034024
申请日：2004-10-13
申请人： TIMEX GROUP BV , PLANCON MICHEL G , GALIE LOUIS M , BURKHARDT WOLFGANG , STOTZ GERHARD , ZACHMANN HELMUT , GRAU SIEGFRIED
发明人： PLANCON MICHEL G , GALIE LOUIS M , BURKHARDT WOLFGANG , STOTZ GERHARD , ZACHMANN HELMUT , GRAU SIEGFRIED
IPC分类号： G04B20060101 , G04B19/20 , G04C17/00
CPC分类号： G04C17/0066
摘要： A timepiece comprising a date display, comprising a date display assembly comprising a date ring, a first gearing assembly being meshingly coupled to the date ring for causing the rotation of the date ring; and a stepping motor comprising a rotor, wherein the rotor of the stepping motor is rotateable coupled to the at least one or more wheels of the first gearing assembly, wherein the rotation of the rotor causes the date ring to rotate; a date-keeping assembly operatively coupled to the date display assembly, comprising: at least a second gearing assembly comprising at least an hour wheel and a detection wheel assembly, wherein at least certain rotational increments of the detection wheel, and the clockwise or counterclockwise direction thereof, causes the rotor of the stepping motor to rotate so that the date ring can be rotated in one of a clockwise or counterclockwise direction; whereby the rotation of the hour wheel through a predetermined midnight position results in that the stepping motor causes the date ring to rotate a predetermined number of degrees, thereby advancing either in the forward or backward direction a displayed digit on the date ring representing a valid date. Methodologies for setting and adjustment are also provided.
摘要翻译：一种包括日期显示的钟表，包括日期显示组件，包括日期环，与所述日期环啮合的第一齿轮组件，用于引起所述日期环的旋转; 以及包括转子的步进马达，其中所述步进马达的转子可旋转地联接到所述第一齿轮组件的所述至少一个或多个车轮，其中所述转子的旋转使得所述日期环旋转; 可操作地联接到日期显示组件的日期保持组件，包括：至少第二传动组件，其包括至少一个小时轮和检测轮组件，其中所述检测轮的至少一定的旋转增量以及顺时针或逆时针方向使步进电动机的转子旋转，使得日期环能够以顺时针或逆时针方向中的一个方向旋转; 由此，通过预定的午夜位置的时轮的旋转导致步进电机使日期环旋转预定的数量，从而在向前或向后方向上前进表示有效日期的日期环上的显示的数字。还提供了设置和调整方法。

6. 发明申请

WO2009033588A2 SELF-CONTROLLED INSULIN DELIVERY SYSTEM 审中-公开
标题翻译：自我控制的胰岛素输送系统
公开(公告)号：WO2009033588A2
公开(公告)日：2009-03-19
申请号：PCT/EP2008/007149
申请日：2008-09-02
申请人： F. HOFFMANN-LA-ROCHE AG , BURKHARDT, Wolfgang
发明人： BURKHARDT, Wolfgang
IPC分类号： A61K9/127 , A61K38/28
CPC分类号： A61K9/127 , A61K38/28
摘要： The present invention relates to a glucose sensitive vesicle (preferably a multi-lamellar liposome) comprising an insulin-independent glucose transporter integrated into the membrane of the liposome, which further comprises glucokinase, insulin, Mg++ and ATP. Glucose diffuses into the liposome depending on its concentration and will be converted to glucose-6-phosphate. The accumulation of glucose-6-phosphate eventually causes the vesicle to burst. Thus, these liposomes allow an automatic adjustment of insulin levels in a glucose-dependent manner and are, therefore, useful for the treatment of diabetic patients.
摘要翻译：本发明涉及包含整合到脂质体膜中的不依赖胰岛素的葡萄糖转运蛋白的葡萄糖敏感小泡（优选多层脂质体），其还包含葡糖激酶，胰岛素，Mg ++和ATP。葡萄糖根据其浓度扩散到脂质体中，并将转化为葡萄糖-6-磷酸。葡萄糖-6-磷酸的积累最终导致囊泡爆裂。因此，这些脂质体允许以葡萄糖依赖性方式自动调节胰岛素水平，因此可用于治疗糖尿病患者。

7. 发明申请

WO2008045379A3 ELECTRONIC DEVICE WITH CHANGEABLE DISPLAY CONFIGURATIONS 审中-公开
标题翻译：具有可更改显示配置的电子设备
公开(公告)号：WO2008045379A3
公开(公告)日：2008-11-13
申请号：PCT/US2007021487
申请日：2007-10-04
申请人： TIMEX GROUP BV , GALIE LOUIS M , BURKHARDT WOLFGANG , STOTZ GERHARD , SCHNELL HANS G , BURGHAUSEN ROLAND
发明人： GALIE LOUIS M , BURKHARDT WOLFGANG , STOTZ GERHARD , SCHNELL HANS G , BURGHAUSEN ROLAND
IPC分类号： G04B19/00
CPC分类号： G04G17/045 , G04G9/00
摘要： A display assembly for a wearable electronic device. The display assembly is disposed within a housing of the wearable electronic device. The electronic device is constructed to receive at least a first and second dial assembly each of which is adapted to provide a different display configuration. The display assembly comprises a liquid crystal display assembly comprising at least two display sections, driving means for providing driving signals to the respective display sections; and a controller, operatively coupled to the driving means, for signaling the driving means to provide the driving signals; wherein the display configuration of the wearable electronic device is changeable based on the dial assembly operatively coupled within the housing, wherein the first dial assembly provides for the viewability of at least the first display section and the second dial assembly provides for the viewability of at least the second display section. A method of customizing the display of a wearable electronic device is also provided. In a specific embodiment, the wearable electronic device is a wristwatch.
摘要翻译：一种用于可穿戴电子装置的显示组件。显示组件设置在可穿戴电子设备的壳体内。电子设备被构造成接收至少一个第一和第二拨盘组件，每个拨盘组件适于提供不同的显示配置。显示组件包括：液晶显示组件，包括至少两个显示部分，用于向各个显示部分提供驱动信号的驱动装置; 以及控制器，可操作地耦合到所述驱动装置，用于发信号通知所述驱动装置以提供所述驱动信号; 其中所述可佩戴电子装置的显示结构基于可操作地联接在所述壳体内的所述刻度盘组件而是可改变的，其中所述第一拨盘组件提供至少所述第一显示部分的可视性，并且所述第二拨盘组件提供至少可视性第二显示部。还提供了一种定制可穿戴电子装置的显示的方法。在具体实施例中，可穿戴电子装置是手表。

8. 发明申请

WO2008045379A2 ELECTRONIC DEVICE WITH CHANGEABLE DISPLAY CONFIGURATIONS 审中-公开
标题翻译：具有可变显示配置的电子设备
公开(公告)号：WO2008045379A2
公开(公告)日：2008-04-17
申请号：PCT/US2007/021487
申请日：2007-10-04
申请人： TIMEX GROUP B.V. , GALIE, Louis, M. , BURKHARDT, Wolfgang , STOTZ, Gerhard , SCHNELL, Hans, G. , BURGHAUSEN, Roland
发明人： GALIE, Louis, M. , BURKHARDT, Wolfgang , STOTZ, Gerhard , SCHNELL, Hans, G. , BURGHAUSEN, Roland
IPC分类号： G04B19/00
CPC分类号： G04G17/045 , G04G9/00
摘要： A display assembly for a wearable electronic device. The display assembly is disposed within a housing of the wearable electronic device. The electronic device is constructed to receive at least a first and second dial assembly each of which is adapted to provide a different display configuration. The display assembly comprises a liquid crystal display assembly comprising at least two display sections, driving means for providing driving signals to the respective display sections; and a controller, operatively coupled to the driving means, for signaling the driving means to provide the driving signals; wherein the display configuration of the wearable electronic device is changeable based on the dial assembly operatively coupled within the housing, wherein the first dial assembly provides for the viewability of at least the first display section and the second dial assembly provides for the viewability of at least the second display section. A method of customizing the display of a wearable electronic device is also provided. In a specific embodiment, the wearable electronic device is a wristwatch.
摘要翻译：
用于可穿戴电子设备的显示组件。显示组件设置在可穿戴电子设备的外壳内。电子设备被构造成接收至少第一和第二拨号组件，每个拨号组件适于提供不同的显示配置。该显示组件包括液晶显示组件，该液晶显示组件包括至少两个显示部分，用于向各个显示部分提供驱动信号的驱动装置; 以及控制器，可操作地耦合到所述驱动装置，用于向所述驱动装置发信号以提供所述驱动信号; 其中所述可穿戴电子装置的显示配置可基于可操作地耦合在所述外壳内的所述拨盘组件而改变，其中所述第一拨盘组件提供至少所述第一显示区段的可视性，并且所述第二拨盘组件提供至少可见度第二显示部分。还提供了定制可穿戴电子设备的显示的方法。在具体实施例中，可穿戴电子设备是手表。

9. 发明申请

WO2007074146A1 MULTIMODE ELECTRONIC DEVICE WITH CALIBRATING/SETTING MECHANISM 审中-公开
标题翻译：具有校准/设置机构的多模电子设备
公开(公告)号：WO2007074146A1
公开(公告)日：2007-07-05
申请号：PCT/EP2006/070170
申请日：2006-12-22
申请人： TIMEX GROUP B.V. , BURKHARDT, Wolfgang , STOTZ, Gerhard , SCHNELL, Hans , DIETRICH, Martin , KALMBACH, Ulrich , PLANCON, Michel
发明人： BURKHARDT, Wolfgang , STOTZ, Gerhard , SCHNELL, Hans , DIETRICH, Martin , KALMBACH, Ulrich , PLANCON, Michel
IPC分类号： G04C9/00 , G04C17/00
CPC分类号： G04C17/0058 , G04C9/08
摘要： An electronic device comprising a controller having an integrated circuit operable in at least a first and second mode, and a dial (20) having a window (22) through which at least one indicator is visible, wherein the electronic device comprises a mode indicator (30) positioned on an actuation mechanism side of the dial, wherein the mode indicator (30) has at least a first indicator and a second indicator each respectively representative of one of the at least two modes within which the electronic device is operable; a gearing assembly comprising one or more wheels, being meshingly coupled to the mode indicator so that the rotation of the one or more wheels causes the rotation of the mode indicator; an actuation mechanism, rotateably coupled to the at least one or more wheels of the gearing assembly, wherein the rotation of the actuation mechanism causes the rotation of the mode indicator; wherein the integrated circuit controls the actuation of the actuation mechanism so as to initiate the rotation of the mode indicator; and actuation means, operatively coupled to the controller, for selecting the mode within which the integrated circuit is operable, wherein the mode within which the integrated circuit is operating is visible through the window (22) in the dial (20); wherein the mode in which the integrated circuit is operating is indicated by the indicator visible in the window.
摘要翻译：一种电子设备，包括具有可在至少第一和第二模式中操作的集成电路的控制器，以及具有窗口（22）的表盘（20），至少一个指示器通过所述窗口可见，其中所述电子设备包括模式指示器 30）定位在所述表盘的致动机构侧上，其中所述模式指示器（30）至少具有第一指示器和第二指示器，每个指示器和第二指示器分别代表所述电子设备可操作的所述至少两种模式中的一种模式; 包括一个或多个车轮的齿轮组件，其啮合地联接到所述模式指示器，使得所述一个或多个车轮的旋转引起所述模式指示器的旋转; 致动机构，其可旋转地联接到所述齿轮组件的所述至少一个或多个轮，其中所述致动机构的旋转引起所述模式指示器的旋转; 其中所述集成电路控制所述致动机构的致动，以便启动所述模式指示器的旋转; 以及可操作地耦合到所述控制器的用于选择所述集成电路可操作的模式的致动装置，其中所述集成电路正在操作的模式通过所述拨盘（20）中的窗口（22）是可见的; 其中集成电路正在操作的模式由窗口中可见的指示器指示。

10. 发明申请

WO2006134158A3 DATE DISPLAY ASSEMBLY FOR AN ELECTRONIC DEVICE 审中-公开
公开(公告)号：WO2006134158A3
公开(公告)日：2006-12-21
申请号：PCT/EP2006/063262
申请日：2006-06-15
申请人： TIMEX GROUP B.V. , SCHWARTZ, Herbert , BURKHARDT, Wolfgang
发明人： SCHWARTZ, Herbert , BURKHARDT, Wolfgang
IPC分类号： G04C17/00 , G04B19/247
摘要： A date display assembly (100) for displaying the day of the month in an electronic device. The assembly comprises a units ring (105) and a tens disc (120), the units ring comprising at least one series of numerals from 0 to 9 and the tens disc comprising a series of numerals from at least 1 to 3 and optionally the numeral 0. The units ring and the tens disc are positioned relative to each other so as to display in the space of a window (122) two numerals side by side, one of which is carried by the units ring (105) and the other of which is carried by the tens disc (120). The units ring is divided into ten sectors or a multiple of ten sectors each separating the numerals 0 to 9, the one sector separating the numerals 9 - 0 having an angular extent equal to 3/4 of the angular extent of the sectors separating the other numerals. In the preferred embodiment, the device is a timepiece and a wristwatch in particular.

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