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1. 发明申请

WO2023063698A1 NOVEL CAPSID ASSEMBLY INHIBITORS 审中-公开
公开(公告)号：WO2023063698A1
公开(公告)日：2023-04-20
申请号：PCT/KR2022/015335
申请日：2022-10-12
申请人： AM SCIENCES INC , KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人： JEONG, Nakcheol , LEE, Misun , SIM, Heewoo , KIM, Myungjin , KIM, Jung-Hee , HAN, Soo Bong , JUNG, Young Sik , KIM, Hye jin , YUN, Chang Soo , CHO, Heeyeong , KIM, Mee Hyein , LEE, Joo Youn
IPC分类号： C07D487/04 , A61K31/55 , A61K31/4439 , A61P31/20 , A61P31/14 , A61P31/18 , C07D401/12
摘要： The present invention relates to a series of novel triazolomethylurea derivatives, and the use thereof for the inhibition of capsid assembly and the prevention or treatment of viral diseases through the inhibition.

2. 发明申请

WO2023063697A1 NOVEL CAPSID ASSEMBLY INHIBITORS 审中-公开
公开(公告)号：WO2023063697A1
公开(公告)日：2023-04-20
申请号：PCT/KR2022/015333
申请日：2022-10-12
申请人： AM SCIENCES INC , KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人： JEONG, Nakcheol , LEE, Misun , SIM, Heewoo , KIM, Myungjin , KIM, Jung-Hee , HAN, Soo Bong , JUNG, Young Sik , KIM, Hye jin , YUN, Chang Soo , CHO, Heeyeong , KIM, Mee Hyein , LEE, Joo Youn
IPC分类号： C07D403/02 , A61K31/506 , A61P31/12 , A61P31/20 , A61P31/14 , A61P31/18 , C07D403/14 , C07D401/14 , C07D491/052
摘要： The present invention relates to a series of novel pyrazolylmethylurea derivatives, and the use thereof for the inhibition of capsid assembly and the prevention or treatment of viral diseases through the inhibition.

3. 发明申请

WO2022124748A1 피라졸로피리미딘 설폰아마이드 유도체 및 이를 유효성분으로 포함하는 암 관련 질환의 예방 또는 치료용 약학적 조성물 审中-公开
公开(公告)号：WO2022124748A1
公开(公告)日：2022-06-16
申请号：PCT/KR2021/018409
申请日：2021-12-07
申请人： 한국화학연구원 KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY [KR]/[KR] , 계명대학교 산학협력단 INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY [KR]/[KR]
发明人： 전문국 JEON, Moon Kook , 최길돈 CHOI, Gil Don , 이윤한 LEE, Yun Han , 임병호 LIM, Byung Ho , 정명은 JUNG, Myoung Eun , 김연주 KIM, Yeon Ju
IPC分类号： C07D487/04 , A61K31/519 , A61K45/06 , A61P35/00
摘要： 본 발명은 하기 화학식 1로 표시되는 피라졸로피리미딘 설폰아마이드 유도체, 이의 이성질체 또는 이의 약학적으로 허용가능한 염을 제공한다. 본 발명에 따른 화학식 1의 피라졸로피리미딘 설폰아마이드 유도체는 우수한 Wee1 저해 활성 효과를 가지므로, 세포분열주기 조절 및 암줄기세포 기능 억제 등을 통해 암세포의 성장과 전이를 억제할 수 있으며, 암세포가 비정상적인 증식을 보이는 상태인 암 관련 질환의 예방 또는 치료에 유용하게 사용될 수 있다. 또한 본 발명에 따른 피라졸로피리미딘 설폰아마이드 유도체는 화학 항암제, 면역 항암제 및 표적 치료제 등의 화학요법 또는 방사선 요법과의 병용을 통해 암 관련 질환의 예방 또는 치료에 유용하게 사용될 수 있다. [화학식 1]

4. 发明申请

WO2017095042A1 DEVELOPMENT OF BIOMASS PRETREATMENT TECHNOLOGY VIA CONTROLLED FEEDING SYSTEM OF FIBROUS BIOMASS INTO CONTINUOUS HIGH-PRESSURE REACTOR 审中-公开
标题翻译：利用纤维生物质控制进料系统将生物质预处理技术发展为连续式高压反应器
公开(公告)号：WO2017095042A1
公开(公告)日：2017-06-08
申请号：PCT/KR2016/013094
申请日：2016-11-14
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人： YU, Ju-Hyun , EOM, In-Yong , JEGAL, Jong-Geon , KOO, Myung-Hoi
IPC分类号： B01J4/00 , B01J19/24 , B01J19/00 , B01F7/08 , C12P1/00 , B01J3/00 , B01J3/02 , B65G33/18 , B02C19/22 , B02C7/02
CPC分类号： B02C23/24 , B01F7/00866 , B01F7/085 , B01F7/086 , B01J3/00 , B01J3/02 , B01J4/00 , B01J19/00 , B01J19/24 , B02C7/02 , B02C7/04 , B02C19/22 , B65G33/18 , C12P1/00
摘要： The present disclosure relates to a high-pressure reactor for continuous hydrolysis of lignocellulosic biomass and a method for continuous high-pressure pretreatment. The present disclosure is very useful in continuous high-temperature, high-pressure steam explosion and hydrolysis of biomass because the surface area can be increased and the aspect ratio (fiber width/fiber length) can be decreased through quick hydration and abrasion and various crushed lignocellulosic biomass having different properties can be continuously injected into the high-pressure reactor, regardless of the kind of biomass.
摘要翻译：本公开涉及用于木质纤维素生物质的连续水解的高压反应器和用于连续高压预处理的方法。本公开在连续高温，高压蒸汽爆炸和生物质水解中非常有用，因为可以增加表面积并且通过快速水化和磨损以及各种压碎可以降低纵横比（纤维宽度/纤维长度）无论生物质的种类如何，具有不同特性的木质纤维素生物质都可以连续地注入高压反应器中。

5. 发明申请

WO2017008033A1 PYRROLIDINE CARBOXAMIDO DERIVATIVES AND METHODS FOR PREPARING AND USING THE SAME 审中-公开
标题翻译：吡咯烷羧酰胺衍生物及其制备和使用方法
公开(公告)号：WO2017008033A1
公开(公告)日：2017-01-12
申请号：PCT/US2016/041563
申请日：2016-07-08
申请人： REASEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY , KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人： CHOI, Gildon , RHEE, Sang, Dal , ALI, Imran , CHAE, Chong, Hak , PARK, Seok Hee , JEON, Moon, Kook , LEE, Youn, Sook , LEE, Kwangho
IPC分类号： C07D207/04 , C07D207/10 , C07D403/06 , A61K31/40 , A61K31/4025 , A23L1/30
CPC分类号： C07K5/1024 , A61K38/00 , C07K5/0823 , C07K5/1008 , C07K5/1016
摘要： Pyrrolidine carboxamido derivatives, optical isomers thereof, and salts thereof that are able to prevent, improve, and/or treat inflammatory conditions, including inflammatory bowel disease, and methods for preparing and using the same are provided.
摘要翻译：提供能够预防，改善和/或治疗炎症性疾病，包括炎症性肠病的吡咯烷甲酰胺衍生物，其光学异构体及其盐及其制备和使用方法。

6. 发明申请

WO2016186454A1 ADSORBENTS COMPRISING ORGANIC-INORGANIC HYBRID NANOPOROUS MATERIALS FOR SORPTION OF WATER OR ALCOHOL AND USE THEREOF 审中-公开
标题翻译：含有有机无机杂化纳米材料的吸附剂用于水或酒精的吸收及其使用
公开(公告)号：WO2016186454A1
公开(公告)日：2016-11-24
申请号：PCT/KR2016/005276
申请日：2016-05-18
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
发明人： CHANG, Jong San , LEE, U Hwang , HWANG, Young Kyu , SERRE, Christian , DEVIC, Thomas , CADIAU, Amandine , STOCK, Norbert , REIMER, Nele , WHARMBY, Michael T.
IPC分类号： B01J20/02 , F24F3/14 , B01J20/22 , F25B17/02 , B01J20/00
CPC分类号： B01J20/226 , B01D53/04 , B01D53/261 , B01D2253/204 , B01D2257/704 , B01D2257/80 , B01D2259/40088 , B01J20/28057 , B01J20/28069 , B01J20/3085 , B01J20/3433 , B01J20/3483 , H01L51/5259 , H01M10/4235
摘要： Provided are a water and/or alcohol adsorbent including organic-inorganic hybrid nanoporous materials, and use thereof, and more particularly, a water and/or alcohol adsorbent having a high adsorption amount at a low relative humidity or partial pressure, of which desorption/regeneration is possible at a low temperature, the water and/or alcohol adsorbent including organic-inorganic hybrid nanoporous materials having 0.5 to 3 mol of a hydroxyl group (OH) or a hydroxide anion group (OH - ) per 1 mol of a central metal ion, and use thereof.
摘要翻译：提供包括有机 - 无机杂化纳米多孔材料的水和/或醇吸附剂及其用途，更具体地，涉及在低相对湿度或分压下具有高吸附量的水和/或醇吸附剂，其中解吸/ 在低温下再生是可能的，水和/或醇吸附剂包括有机 - 无机混合纳米多孔材料，每1摩尔中心金属具有0.5-3摩尔羟基（OH）或氢氧根阴离子基团（OH-）离子及其用途。

7. 发明申请

WO2011146918A2 MACROCYCLIC COMPOUNDS AND METHODS OF TREATMENT 审中-公开
标题翻译： MACROCYCLIC化合物和治疗方法
公开(公告)号：WO2011146918A2
公开(公告)日：2011-11-24
申请号：PCT/US2011/037545
申请日：2011-05-23
申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. , DUKE UNIVERSITY , KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , LUESCH, Hendrik , HONG, Jiyong , KIM, Seong, Hwan
发明人： LUESCH, Hendrik , HONG, Jiyong , KIM, Seong, Hwan
CPC分类号： A61K31/429 , A61K45/06 , C07D498/18 , A61K2300/00
摘要： The instant invention describes macrocyclic compounds having therapeutic activity, and methods of treating disorders such as methods of modulating bone processes, and methods of treating bone-related disease, disorders, and symptoms thereof.
摘要翻译：本发明描述了具有治疗活性的大环化合物和治疗疾病如调节骨过程的方法的方法，以及治疗骨相关疾病，病症和症状的方法。

8. 发明申请

WO2011071213A1 PHOSPHOR-TITANIUM DIOXIDE NANOCOMPOSITE USEFUL AS PHOTOCATALYST AND METHOD FOR PREPARATION THEREOF 审中-公开
标题翻译：作为光催化剂有用的二氧化钛 - 二氧化钛纳米复合材料及其制备方法
公开(公告)号：WO2011071213A1
公开(公告)日：2011-06-16
申请号：PCT/KR2010/002940
申请日：2010-05-10
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , RYU, Ho Jin , CHANG, Tae Sun , THUBE, Dilip Raosaheb
发明人： RYU, Ho Jin , CHANG, Tae Sun , THUBE, Dilip Raosaheb
IPC分类号： B82B1/00 , B01J21/06 , B01J23/10
CPC分类号： B01J35/004 , B01J23/10 , B01J37/033 , C02F1/32 , C02F1/725 , C02F2305/10
摘要： Provided are a phosphor-titanium dioxide nanocomposite useful as a photocatalyst and a method for preparing the same, more particularly a novel phosphor-titanium dioxide nanocomposite including nanoparticles prepared from a CaAl 2 O 4 :Eu 2+ ,Nd 3+ phosphor and a titanium(IV) precursor by a sol-gel method, having superior thermal stability to be present as anatase crystal phase even after heat treatment at 400 ºC to 600 ºC and exhibiting continued catalytic activity in a broad wavelength region of UV to visible and under a light-free condition using the energy stored in the phosphor, and a method for preparing the same.
摘要翻译：提供可用作光催化剂的磷光体 - 二氧化钛纳米复合材料及其制备方法，更具体地说，包括由CaAl 2 O 4：Eu 2+，Nd 3+荧光体和钛（IV）前体通过溶胶制备的纳米颗粒的新型磷光体 - 二氧化钛纳米复合材料 - 凝胶法，即使在400℃至600℃的热处理后也具有优异的热稳定性，作为锐钛矿晶相存在，并且在紫外线的宽波长范围内在可见光和无光条件下使用储存的能量表现出持续的催化活性在荧光体中，以及其制备方法。

9. 发明申请

WO2011027921A2 CATALYST FOR DIRECT PRODUCTION OF LIGHT OLEFINS AND PREPARATION METHOD THEREOF 审中-公开
标题翻译：直接生产光油的催化剂及其制备方法
公开(公告)号：WO2011027921A2
公开(公告)日：2011-03-10
申请号：PCT/KR2009/004998
申请日：2009-09-04
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , KANG, Suk-Hwan , BAE, Jong-Wook , JUN, Ki-won , LEE, Yun-Jo , KIM, Hyo Jean
发明人： KANG, Suk-Hwan , BAE, Jong-Wook , JUN, Ki-won , LEE, Yun-Jo , KIM, Hyo Jean
IPC分类号： B01J23/70
CPC分类号： B01J23/8892 , B01J23/002 , B01J23/02 , B01J23/78 , B01J35/1009 , B01J35/1014 , B01J37/0201 , B01J37/0205 , B01J37/0242 , B01J37/031 , B01J37/033 , B01J37/08 , B01J37/10 , B01J37/18 , B01J2523/00 , C07C1/044 , C07C2523/02 , C07C2523/04 , C07C2523/34 , C07C2523/72 , C07C2523/745 , C07C2523/75 , C07C2523/78 , C07C2523/889 , C10G2/332 , Y02P20/52 , C07C11/04 , C07C11/08 , C07C11/06 , B01J2523/13 , B01J2523/23 , B01J2523/842 , B01J2523/845 , B01J2523/72 , B01J2523/17
摘要： Disclosed herein is a novel F-T catalyst system suitable for the selective production of light olefins from syngas produced from natural gas (syngas to olefins; STO), which contains an iron-based catalyst and a calcium oxide (CaOx) prepared by a sol-gel process and shows an increased yield of C 2 -C 4 light olefins and improved catalyst stability.
摘要翻译：本文公开了一种新型的FT催化剂体系，其适用于从由天然气（合成气至烯烃; STO）生产的合成气中选择性生产轻质烯烃，其中含有铁基催化剂和通过溶胶 - 凝胶制备的氧化钙（CaO x）并显示了C2-C4轻质烯烃的产率提高和催化剂稳定性的提高。

10. 发明申请

WO2011013880A2 METHOD FOR PREPARING DIALKYL CARBONATE 审中-公开
标题翻译：制备碳酸二乙酯的方法
公开(公告)号：WO2011013880A2
公开(公告)日：2011-02-03
申请号：PCT/KR2009/006726
申请日：2009-11-27
申请人： KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY , KOH, Jae Cheon , KIM, Chul Ung , KIM, Yun Min
发明人： KOH, Jae Cheon , KIM, Chul Ung , KIM, Yun Min
IPC分类号： C07C68/00
CPC分类号： C07C68/00 , C07C69/96
摘要： The present invention provides a method for preparing dialkyl carbonate from urea or alkyl carbamate and alkyl alcohol using an ionic liquid comprising a cation, which produces a hydrogen ion, and a hydrophobic anion containing fluorine with high temperature stability in the presence of catalyst containing a metal oxide or hydrotalcite. Since the present invention can prepare dialkyl carbonate at a pressure lower than those of existing methods, it does not require an expensive pressure control device and peripheral devices for maintaining high pressure including the installation cost. It is also the method for preparing a dialkyl carbonate with high yield, thus improving economical efficiency. Moreover, the method of the present invention hardly produces any waste during the process and is thus an eco-friendly method.
摘要翻译：本发明提供一种在含有金属的催化剂存在下，使用含有产生氢离子的阳离子的离子液体和含有氟的疏水性阴离子从尿素或烷基氨基甲酸酯和烷基醇制备碳酸二烷基酯的方法，氧化物或水滑石。由于本发明可以以比现有方法低的压力制备碳酸二烷基酯，所以不需要昂贵的压力控制装置和用于保持高压的外围装置，包括安装成本。也是以高产率制备碳酸二烷基酯的方法，从而提高了经济性。此外，本发明的方法在该方法中几乎不产生浪费，因此是一种环保方法。

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