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    • 1. 发明申请
    • ARTIFICIAL, FLEXIBLE VALVES AND METHODS OF FABRICATING AND SERIALLY EXPANDING THE SAME
    • 人工,柔性阀及其制造方法及其扩展方法
    • WO2015171743A3
    • 2015-12-17
    • PCT/US2015029442
    • 2015-05-06
    • BAYLOR COLLEGE MEDICINEUNIV RICE WILLIAM M
    • JUSTINO HENRIHARRINGTON DANIELCHUN KWONSOO
    • A61F2/24A61F2/82A61F2/86
    • A61F2/2418A61F2/2415A61F2220/0008A61F2230/0008A61F2230/0069A61F2250/0098
    • One aspect of the invention provides an artificial, flexible valve including: a stent defining a wall and a plurality of leaflets extending from the wall of the stent. The plurality of leaflets form a plurality of coaptation regions between two adjacent leaflets. The coaptation regions include extensions along a z-axis and adapted and are configured to form a releasable, but substantially complete seal when the leaflets are in a closed position. Another aspect of the invention provides an artificial, flexible valve including: a stent defining a wall and a plurality of leaflets extending from the wall of the stent. Each of the plurality of leaflets terminates in a commissure line. The commissure lines deviate from a hyperbola formed in the x-y plane by at least one deviation selected from the group consisting of: a deviation in the z-direction and one or more curves relative to the hyperbola.
    • 本发明的一个方面提供了一种人造的柔性阀,包括:支架,其限定壁和从支架的壁延伸的多个小叶。 多个传单在两个相邻传单之间形成多个接合区域。 接合区域包括沿z轴的延伸部分,并且适于并且构造成当传单处于关闭位置时形成可释放但基本上完整的密封。 本发明的另一方面提供一种人造的柔性阀,包括:支架,其限定壁和从支架的壁延伸的多个传单。 多个传单中的每一个终止于连合线。 连合线偏离在x-y平面上形成的双曲线,所述双曲线选自由以下组成的组中的至少一个偏差:z方向上的偏差和相对于双曲线的一个或多个曲线。