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1. 发明申请

WO2012137113A1 IMAGE PROCESSING SYSTEM AND METHOD. 审中-公开
标题翻译：图像处理系统和方法。
公开(公告)号：WO2012137113A1
公开(公告)日：2012-10-11
申请号：PCT/IB2012/051536
申请日：2012-03-30
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GmbH , WENZEL, Fabian , TRUYEN, Roel , ERMES, Jean-Pierre, Franciscus, Alexander, Maria , DEN HARDER, Johan, Michiel
发明人： WENZEL, Fabian , TRUYEN, Roel , ERMES, Jean-Pierre, Franciscus, Alexander, Maria , DEN HARDER, Johan, Michiel
IPC分类号： G06T15/20 , H04N13/04
CPC分类号： G06T19/003 , G06F1/1694 , G06F3/04815 , G06F2200/1637 , G06F2203/04806 , G06T15/20 , H04N13/349 , H04N13/388 , H04N13/398
摘要： Image processing system 100 for enabling a user to navigate through image data having at least three spatial dimensions by displaying views 155 of the image data, the image processing system comprising an image device 110 comprising a display 130 for displaying the views of the image data and an orientation sensor 120 for measuring an orientation of the image device with respect to a reference orientation for providing rotation data 125 indicative of a device rotation of the image device, means 140 for establishing a center of rotation in the image data, and an image processor 150 for establishing the views of the image data in relation to the device rotation by, for establishing a current view, (i) receiving the rotation data from the orientation sensor, (ii) establishing a view rotation in relation to the device rotation, and (iii) establishing the current view in dependence on the view rotation around the center of rotation with respect to a reference view.
摘要翻译：图像处理系统100，用于使用户能够通过显示图像数据的视图155导航具有至少三个空间维度的图像数据，该图像处理系统包括图像装置110，该图像装置110包括用于显示图像数据的视图的显示器130和用于测量图像装置相对于参考方向的取向的方向传感器120，用于提供指示图像装置的装置旋转的旋转数据125，用于在图像数据中建立旋转中心的装置140和图像处理器 150，用于通过用于建立当前视图来建立与装置旋转相关的图像数据的视图，（i）从定向传感器接收旋转数据，（ii）建立与装置旋转相关的视图旋转;以及（iii）根据相对于参考视图围绕旋转中心的视图旋转来建立当前视图。

2. 发明申请

WO2012059851A1 IMAGE CONTENT BASED PREDICTION AND IMAGE CACHE CONTROLLER 审中-公开
标题翻译：基于图像内容的预测和图像缓存控制器
公开(公告)号：WO2012059851A1
公开(公告)日：2012-05-10
申请号：PCT/IB2011/054797
申请日：2011-10-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WENZEL, Fabian , NETSCH, Thomas , DRIES, Sebastian Peter Michael
发明人： WENZEL, Fabian , NETSCH, Thomas , DRIES, Sebastian Peter Michael
IPC分类号： G06T19/00
CPC分类号： H04L67/1097 , G06T19/003
摘要： Cache controller (120) for use in a system (180) comprising an image client (100) and an image server (140), the image client enabling a user to navigate through image data having at least three spatial dimensions by displaying views of the image data that are obtained from the image server in dependence on navigation requests of the user, and the cache controller comprising a processor (122) configured for obtaining content data indicative of a content shown in a current view of the image client (100), the current view representing a first viewpoint in the three spatial dimensions of the image data, the processor being further configured for predicting a view request of the image client in dependence on the content data, the view request corresponding to a view representing a second viewpoint in the three spatial dimensions of the image data, and a communication means (124) for obtaining the view from the image server in dependence on the view request, and for caching the view in a cache (130).
摘要翻译：用于在包括图像客户机（100）和图像服务器（140）的系统（180）中使用的高速缓存控制器（120），所述图像客户端使得用户能够通过显示所述图像客户端的视图来导航具有至少三个空间维度的图像数据图像数据，其根据用户的导航请求从图像服务器获得，并且所述高速缓存控制器包括被配置用于获取指示所述图像客户端（100）的当前视图中显示的内容的内容数据的处理器（122）所述当前视图表示所述图像数据的三个空间维度中的第一视点，所述处理器还被配置为根据所述内容数据来预测所述图像客户端的视图请求，所述视图请求对应于表示第二视点的视图图像数据的三个空间维度，以及用于根据视图请求从图像服务器获得视图的通信装置（124），以及用于将视图缓存在ca （130）。

3. 发明申请

WO2012042449A2 IMAGE AND ANNOTATION DISPLAY 审中-公开
标题翻译：图像和声明显示
公开(公告)号：WO2012042449A2
公开(公告)日：2012-04-05
申请号：PCT/IB2011/054189
申请日：2011-09-23
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GmbH , DRIES, Sebastian Peter Michael , WENZEL, Fabian , NETSCH, Thomas
发明人： DRIES, Sebastian Peter Michael , WENZEL, Fabian , NETSCH, Thomas
IPC分类号： G06T19/00
CPC分类号： G06T19/20 , G06T19/00 , G06T2219/004 , G06T2219/008
摘要： A system (100) for displaying a multi-dimensional image and an annotation located therein, the system comprising receiving means (110) for receiving: the multi- dimensional image, the annotation, and representation data associated with the annotation, the representation data being indicative of a preferred representation of the multi-dimensional image and the annotation located therein; display means (130) for displaying an initial representation (300) of the multi-dimensional image and the annotation located therein; input means (120) for enabling a user to provide a visualization request when the initial representation shows at least a first part (310) of the annotation; and the display means (130) being arranged for, after receiving the visualization request, displaying the preferred representation (400) of the multi-dimensional image and the annotation located therein in accordance with the representation data, the preferred representation showing at least a second part (410) of the annotation, the second part being different from the first part.
摘要翻译：一种用于显示位于其中的多维图像和注释的系统（100），所述系统包括接收装置（110），用于接收：所述多维图像，所述注释和与所述注释相关联的表示数据，所述表示数据是指示多维图像和位于其中的注释的优选表示; 显示装置（130），用于显示多维图像的初始表示（300）和位于其中的注释; 输入装置（120），用于当所述初始表示显示至少所述注释的第一部分（310）时，使用户能够提供可视化请求; 并且所述显示装置（130）被布置用于在接收到所述可视化请求之后，根据所述表示数据显示所述多维图像和位于其中的注释的优选表示（400），所述优选表示显示至少第二注释的部分（410），第二部分与第一部分不同。

4. 发明申请

WO2013072843A1 METHOD TO COMPUTE AND PRESENT BRAIN AMYLOID IN GRAY MATTER 审中-公开
标题翻译：计算和存在灰质中的脑亚胺的方法
公开(公告)号：WO2013072843A1
公开(公告)日：2013-05-23
申请号：PCT/IB2012/056379
申请日：2012-11-13
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH
发明人： THIELE, Frank, Olaf , WENZEL, Fabian
IPC分类号： A61B6/03 , G01T1/29 , G06T7/00
CPC分类号： A61B5/0035 , A61B5/0042 , A61B5/055 , A61B6/037 , A61B6/466 , A61B6/501 , A61B6/5247 , G01R33/481 , G06T7/0012 , G06T7/0014 , G06T2207/10088 , G06T2207/10104 , G06T2207/30016
摘要： An imaging work station (20) includes one or more processors programmed to receive (170)an image depicting a distribution of a radiotracer in a brain or other region of interest. The radiotracer includes at least one of [18F]-Flutemetamol, [18F]-Florbetaben, and [18F]-Florbetapir which highlights amyloid deposits. The image and a template or an MRI image of the region of interest which includes a segmented anatomical feature, such as gray matter, are registered (180)to a common space. A volume representation of the image which depicts the distribution of the radiotracer in the segmented gray matter and suppresses the radiotracer outside of the segmented anatomical feature in white matter is extracted (210).
摘要翻译：成像工作站（20）包括被编程为接收（170）描绘大脑或其他感兴趣区域中的放射性示踪剂的分布的图像的一个或多个处理器。放射性示踪剂包括突出淀粉样蛋白沉积物的[18 F] - 十六烷基胺，[18 F] - 格列贝星和[18F] - 格列贝皮中的至少一种。包括分割的解剖特征（例如灰质）的感兴趣区域的图像和模板或MRI图像被记录（180）到公共空间。提取了描绘分段灰质中放射性示踪剂的分布并且抑制白质中分段解剖特征之外的放射性示踪剂的图像的体积表示（210）。

5. 发明申请

WO2008155682A1 MODEL-BASED DIFFERENTIAL DIAGNOSIS OF DEMENTIA AND INTERACTIVE SETTING OF LEVEL OF SIGNIFICANCE 审中-公开
标题翻译：基于模型的差异诊断和意义层次的交互设置
公开(公告)号：WO2008155682A1
公开(公告)日：2008-12-24
申请号：PCT/IB2008/052081
申请日：2008-05-27
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V., , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WENZEL, Fabian , YOUNG, Stewart, M. , VIK, Torbjoern , THIELE, Frank, O. , BUCHERT, Ralph
发明人： WENZEL, Fabian , YOUNG, Stewart, M. , VIK, Torbjoern , THIELE, Frank, O. , BUCHERT, Ralph
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T2200/24 , G06T2207/10104 , G06T2207/20092 , G06T2207/30016
摘要： When detecting and classifying hypo-metabolic regions in the brain to facilitate dementia diagnosis, a patient's brain scan image, generated using an FDG-PET scan, is compared to a plurality of hypo-metabolic region patterns in brain scan images associated with a plurality of types of dementia. In a fully automated mode, the patient's scan is compared to all scans stored in a knowledge base, and a type of dementia associated with a most likely match is output to a user along with a highlighted image of the patient' s brain. In a semi-automated mode, a user specifies two or more types of dementia, and the patient's scan is compared to scans typical of the specified types. Diagnosis information including respective likelihoods for each type is then output to the user. Additionally, the user can adjust a threshold significance level to increase or decrease a number of voxels that are included in hypo-metabolic regions highlighted in the patient' s brain scan image.
摘要翻译：当检测和分类大脑中的低代谢区域以促进痴呆诊断时，将使用FDG-PET扫描产生的患者的脑扫描图像与多个相关联的脑扫描图像中的多个低代谢区域模式进行比较痴呆症类型。在完全自动化模式下，将患者的扫描与存储在知识库中的所有扫描进行比较，并且将与最可能匹配相关联的一种类型的痴呆与患者大脑的突出显示的图像一起输出给用户。在半自动模式下，用户指定两种或更多种类型的痴呆，并将患者的扫描与特定类型的典型扫描进行比较。然后，向用户输出包括各种类型的各自可能性的诊断信息。此外，用户可以调整阈值显着性水平以增加或减少患者脑扫描图像中突出显示的次代谢区域中包含的体素数量。

6. 发明申请

WO2013105042A2 IMAGE PROCESSING APPARATUS 审中-公开
标题翻译：图像处理设备
公开(公告)号：WO2013105042A2
公开(公告)日：2013-07-18
申请号：PCT/IB2013/050210
申请日：2013-01-10
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH
发明人： DRIES, Sebastian Peter Michael , NETSCH, Thomas , WENZEL, Fabian
IPC分类号： G06T19/00
CPC分类号： G06T15/00 , G06F19/00 , G06F19/321 , G06T7/0012 , G06T7/30 , G06T19/00 , G06T2207/30061 , G06T2210/41 , G06T2219/008
摘要： Image processing apparatus 110 for processing a medical image, comprising an input 120 for obtaining the medical image 122 and medical data 124, the medical image constituting a field of view in three-dimensional [3D] patient data, and the medical data showing an anatomical context of a content of the field of view, an output 130 for providing an output image 160 comprising the medical image and a visualization of the medical data, the medical data constituting non-patient specific medical data, and the imaging processing apparatus further comprising a processor 140 for (i) performing an image alignment between the medical image and the medical data for obtaining a transformation providing a position of the content with respect to its anatomical context, and (ii) using the transformation for establishing a graphical representation of the field of view in the visualization of the medical data at said position.
摘要翻译：用于处理医学图像的图像处理装置110，包括用于获得医学图像122和医疗数据124的输入120，构成三维[3D]患者数据中的视野的医学图像，以及显示解剖学的医学数据视频内容的上下文，用于提供包括医学图像的输出图像160和医学数据的可视化的输出130，构成非患者特定医疗数据的医疗数据，以及成像处理设备，还包括处理器140，用于（i）在医学图像和医疗数据之间执行图像对准以获得相对于其解剖学上下文提供内容的位置的变换，以及（ii）使用用于建立场的图形表示的变换在所述位置处的医疗数据的可视化中。

7. 发明申请

WO2010073190A1 CLASSIFYING ABNORMAL GROWTHS IN A HUMAN BODY 审中-公开
标题翻译：分类人体异常生长
公开(公告)号：WO2010073190A1
公开(公告)日：2010-07-01
申请号：PCT/IB2009/055787
申请日：2009-12-16
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , WIEMKER, Rafael , CARLSEN, Ingwer, C. , BUELOW, Thomas , KABUS, Sven , OPFER, Roland , SABCZYNSKI, Joerg , SCHULZ, Heinrich , WENZEL, Fabian , YOUNG, Stewart
发明人： WIEMKER, Rafael , CARLSEN, Ingwer, C. , BUELOW, Thomas , KABUS, Sven , OPFER, Roland , SABCZYNSKI, Joerg , SCHULZ, Heinrich , WENZEL, Fabian , YOUNG, Stewart
IPC分类号： G06K9/64 , G06T7/00
CPC分类号： G06T7/0014 , G06K9/6211 , G06T2207/10072 , G06T2207/30064
摘要： The invention relates to a method of classifying abnormal growths in a human body. For support of diagnosis and clinical decisions in respect of cancer patients, a database of earlier cases is searched, and the cases with the most resembling constellation of positions, sizes etc. of such growths are presented to the clinical user, together with their respective diagnosis, therapy choice and outcome. The resemblance is not based on the similarity of an individual growth, such as a tumor, but rather on the similarity of the constellation of the entirety of, for example, tumors, metastases and lymph nodes, as identified in diagnostic measurements and on scans of the patient. Techniques such as physical examination, CT scan, PET scan, and MRI scan may be used to collect the data for the constellation records in the database.
摘要翻译：本发明涉及一种对人体异常生长进行分类的方法。为了支持癌症患者的诊断和临床决定，搜索早期病例的数据库，并且将这些生长的位置，大小等最相似的星座的病例呈现给临床用户以及它们各自的诊断，治疗选择和结局。相似之处并不是基于单个生长（例如肿瘤）的相似性，而是基于如诊断测量中确定的整个肿瘤，转移灶和淋巴结的星座的相似度，以及扫描患者。可以使用诸如身体检查，CT扫描，PET扫描和MRI扫描的技术来收集数据库中的星座记录的数据。

8. 发明申请

WO2013080101A3 IMAGE SERVER AND METHOD 审中-公开
公开(公告)号：WO2013080101A3
公开(公告)日：2013-06-06
申请号：PCT/IB2012/056655
申请日：2012-11-23
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS INTELLECTUAL PROPERTY&STANDARDS GMBH
发明人： WENZEL, Fabian , NETSCH, Thomas , DRIES, Sebastian, Peter, Michael , VOGELS, Franciscus, Theodorus, Gerardus, Maria , MAKKAPATI, Vishnu, Vardhan
IPC分类号： H04N7/32 , G06F19/00 , G06T19/00
摘要： Image server 110 for transmitting, to an image client 150, a plurality of two- dimensional [2D] views 122 of three-or higher dimensional [3D] image data for enabling a user operating the image client to navigate through the 3D image data by viewing different ones of the plurality of 2D views, the image server comprising an input 120 for obtaining the plurality of 2D views, a transmitter 130 for transmitting the plurality of 2D views in a transmission order 142 to the image client, and a processor 140 for (i) analyzing contents of the plurality of 2D views for obtaining a respective plurality of view properties, and (ii) establishing the transmission order in dependence on the plurality of view properties for transmitting the plurality of 2D views,based on a decreasing degree of information content of the 2D views.

9. 发明申请

WO2013118001A1 INTERACTIVE OPTIMIZATION OF SCAN DATABASES FOR STATISTICAL TESTING 审中-公开
标题翻译：用于统计测试的扫描数据库的交互式优化
公开(公告)号：WO2013118001A1
公开(公告)日：2013-08-15
申请号：PCT/IB2013/050361
申请日：2013-01-15
申请人： KONINKLIJKE PHILIPS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH
发明人： WENZEL, Fabian , THIELE, Frank Olaf , YOUNG, Stewart
IPC分类号： G06F19/00
CPC分类号： G06F19/321 , G06F17/30091 , G06F17/30247 , G06F17/3053 , G06F19/00 , G06T7/0014 , G06T2207/30168
摘要： Generating a patient image collective (34) includes receiving a plurality of candidate images (20) and associated data. At least one inclusion/exclusion rule (44) is applied to the plurality of candidate images and associated data which results in subsets of candidate images (32). The candidate images are tested which result in at least one quality measure (40). The at least one quality measure (40) and associated candidate images are reviewed. The at least one inclusion/exclusion rule (44) is refined based on the reviewed at least one quality measure (40) by at least one of: adding a rule, modifying a rule, deleting a rule, removing a candidate image; and adding a candidate image. The steps of applying the at least one inclusion/exclusion rule through refining the at least one inclusion/exclusion rule are repeated until an optimized collective of images is generated based on a collective size and the at least one quality measure (40). The generated collective is outputted to a data store (34).
摘要翻译：生成患者图像集合（34）包括接收多个候选图像（20）和相关联的数据。至少一个包含/排除规则（44）被应用于导致候选图像（32）的子集的多个候选图像和相关联的数据。测试候选图像，其导致至少一个质量测量（40）。评估至少一个质量测量（40）和相关联的候选图像。基于所审查的至少一个质量度量（40），至少一个包含/排除规则（44）通过以下至少一个来进行细化：添加规则，修改规则，删除规则，移除候选图像; 并添加候选图像。重复通过细化所述至少一个包含/排除规则来应用所述至少一个包含/排除规则的步骤，直到基于集体大小和所述至少一个质量度量（40）来生成优化的图像集合。生成的集合被输出到数据存储器（34）。

10. 发明申请

WO2008107809A2 AUTOMATED DIAGNOSIS AND ALIGNMENT SUPPLEMENTED WITH PET/MR FLOW ESTIMATION 审中-公开
标题翻译：用PET / MR流量估计补充的自动诊断和对齐
公开(公告)号：WO2008107809A2
公开(公告)日：2008-09-12
申请号：PCT/IB2008/050545
申请日：2008-02-14
申请人： KONINKLIJKE PHILIPS ELECTRONICS, N.V. , U.S. PHILIPS CORPORATION , YOUNG, Stewart, M. , KUHN, Michael , WENZEL, Fabian , CARLSEN, Ingwer, C. , MEETZ, Kirsten , BUCHERT, Ralph
发明人： YOUNG, Stewart, M. , KUHN, Michael , WENZEL, Fabian , CARLSEN, Ingwer, C. , MEETZ, Kirsten , BUCHERT, Ralph
IPC分类号： A61B5/055 , A61B6/00
CPC分类号： A61B6/5247 , A61B5/0035 , A61B5/055 , A61B5/4088 , A61B6/037 , A61B6/507
摘要： A scanner (10) is used to provide images for automated diagnoses of neurodegenerative diseases, such as Alzheimer s disease. The images are registered (90) to a template (78). The aligned image is analyzed (60) in relation to reference image data (76, 80) which has been registered to the template which is contained in a knowledge maintenance engine (70) for similar patterns of hypo-intensity that would indicate (in the case of an FDG tracer) reduced glucose uptake in the brain. The most appropriate reference images for the analysis of the present study are chosen by a filter (74). The present study is then given a dementia score (84) as a diagnostic feature vector that indicates to a clinician the type and severity of the ailment based on the analysis. The scanner (10) can produce PET or other metabolic and MR images for diagnosis. The MR can be used to measure blood flow rate into the brain. From the blood flow rate and the metabolic image, tracer, e.g. FDG, uptake maps can be generated for use in the automated diagnoses.
摘要翻译：扫描器（10）用于提供用于自动诊断神经变性疾病如阿尔茨海默氏病的图像。将图像（90）注册到模板（78）。对已经注册到包含在知识维护引擎（70）中的模板的参考图像数据（76,80）进行对准的图像的分析（60），用于类似的低强度模式，其将指示（在 FDG示踪剂的情况）降低了脑中的葡萄糖摄取。用于本研究分析的最合适的参考图像由滤波器（74）选择。然后，本研究给予痴呆评分（84）作为诊断特征向量，其基于分析向临床医生指示疾病的类型和严重程度。扫描仪（10）可以产生PET或其他代谢和MR图像进行诊断。 MR可用于测量进入脑部的血液流量。从血流速度和代谢图像，示踪剂，例如，可以生成FDG，摄影图可用于自动诊断。

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