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    • 5. 发明申请
    • COMPOSITION FOR PROMOTING THE STABILITY OF STEM CELLS
    • 促进干细胞稳定性的组合物
    • WO2012074265A3
    • 2012-08-23
    • PCT/KR2011009140
    • 2011-11-29
    • RNL BIO CO LTDPARK HYEONG-GEUNKANG SUNG KEUNRA JEONG CHANYIM CHA-OK
    • PARK HYEONG-GEUNKANG SUNG KEUNRA JEONG CHANYIM CHA-OK
    • C12N5/0775A61K35/12C07K14/475C12N5/02
    • C12N5/0663A61K35/28
    • The present invention relates to a composition which can promote the stability of stem cells, and more specifically relates to a composition for promoting the stability of stem cells which contains a mesenchymal stem cell culture and base. The composition for promoting the stability of stem cells according to the present invention has the advantageous effect of promoting the stability of stem cells and maintaining a high survival rate, and, in injectable cell therapeutic agent products that contain the composition for promoting the stability of stem cells according to the present invention, the survival rate of the stem cells comprised in the cell therapeutic agent can be maintained at at least 80% for a long time (10 days), and thus the composition for promoting the stability of stem cells according to the present invention can be used in long-duration transportation of injectable cell therapeutic agent products and, as a consequence of the high survival rates of the stem cells comprised in the cell therapeutic agent, the advantages in cell therapy are outstanding and hence the invention can also be used to advantage in the production of high-quality injectable cell therapeutic agent products.
    • 本发明涉及能够促进干细胞稳定性的组合物,更具体而言,涉及含有间充质干细胞培养物和碱的用于促进干细胞稳定性的组合物。 根据本发明的用于促进干细胞稳定性的组合物具有促进干细胞稳定性并维持高存活率的有利效果,并且在含有用于促进干细胞稳定性的组合物的注射用细胞治疗剂产品 根据本发明的细胞,包含在细胞治疗剂中的干细胞的存活率可以长时间(10天)维持在至少80%,因此根据本发明的用于促进干细胞稳定性的组合物 本发明可以用于可注射细胞治疗剂产品的长时间运输,并且由于细胞治疗剂中包含的干细胞的高存活率的结果,细胞疗法的优点是突出的,因此本发明可以 也可用于生产高质量注射用细胞治疗剂产品。