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1. 发明申请

WO2023067609A1 SYSTEM AND METHOD FOR MONITORING VARIATIONS IN RESPIRATORY BIOMARKERS BY ANALYSING TIDAL BREATHING WAVEFORMS 审中-公开
公开(公告)号：WO2023067609A1
公开(公告)日：2023-04-27
申请号：PCT/IL2022/051118
申请日：2022-10-23
申请人： NANOVATION G.S. LTD.
发明人： SHUSTER, Gregory , BACHAR, Nadav , DANINO, Noy , VOIGT, Wieland
IPC分类号： A61B5/087 , A61B5/08 , A61B5/113 , A61B5/00
摘要： Systems and methods for measuring and monitoring variations in respiratory biomarkers over time by analysing tidal breathing waveforms are presented, comprising: receiving, obtained measurements from a wearable non-invasive measurement system for a period of time; periodically calculating a plurality of sub-breath-cycle respiratory biomarkers of the subject based on the obtained measurements; and monitoring the plurality of sub-breath-cycle respiratory biomarkers of a subject for the period of time to observe an indication of variation in a respiratory function or lung function of the subject.

2. 发明申请

WO2023033278A1 무선형 호흡 모니터링 장치 审中-公开
公开(公告)号：WO2023033278A1
公开(公告)日：2023-03-09
申请号：PCT/KR2022/003434
申请日：2022-03-11
申请人： 서울대학교 산학협력단
发明人： 이규철 , 황윤재 , 김경호
IPC分类号： A61B5/08 , A61B5/087 , A61B5/00
摘要： 무선형 호흡 모니터링 장치에 관해 개시되어 있다. 상기 무선형 호흡 모니터링 장치는 사용자의 코 내부로 삽입되는 삽입부를 갖는 중간 본체부 및 상기 중간 본체부로부터 그 양측으로 연장되어 상기 사용자의 콧볼 부분을 감싸서 잡아주도록 구성된 연장 본체부를 포함하는 본체부 유닛, 상기 삽입부의 내측면에 설치되어 상기 사용자의 코 내부에 배치되는 것으로 압저항 특성을 갖는 복수의 나노 막대를 포함하고 상기 사용자의 호흡에 의한 기류 변화에 따른 상기 나노 막대의 변형에 의한 저항 변화를 이용해서 상기 사용자의 호흡 특성을 센싱하도록 구성된 압저항 센서를 포함할 수 있다.

3. 发明申请

WO2023278636A1 SYSTEMS, METHODS, AND COMPONENTS THEREOF RELATING TO POSITIONAL THERAPY FOR SLEEP APNEA 审中-公开
公开(公告)号：WO2023278636A1
公开(公告)日：2023-01-05
申请号：PCT/US2022/035604
申请日：2022-06-29
申请人： WESPER INC.
发明人： REUVENY, Amir , MORDECHAI, Ahud , PERLMAN, Mordechai , BENNETT, Nathan, Harold
IPC分类号： A61B5/00 , A61B2505/07 , A61B2562/0204 , A61B5/02438 , A61B5/0816 , A61B5/087 , A61B5/1114 , A61B5/1116 , A61B5/14542 , A61B5/4815 , A61B5/4818 , A61B5/4848 , A61B5/7275 , A61B5/7405 , A61B5/7455
摘要： Methods and systems for positional sleep therapy for sleep apnea and other disorders are disclosed. A method may include receiving first data indicative of a person's sleeping position from a first sensor and receiving second data indicative of a respiratory condition, a cardiac condition, a snoring condition, and/or an SpO2 level from a second sensor. The method may further include calculating a position-based risk value from the first data and calculating at least one biometric-based risk value from the second data. The method may further include comparing the calculated risk values to at least one threshold risk value to determine if at least one wake rule has been triggered. If at least one wake rule has been triggered, a stimulation component may be commanded to impart a wake stimulation to the person.

4. 发明申请

WO2022243875A1 MONITORING DEVICE AND SYSTEM 审中-公开
公开(公告)号：WO2022243875A1
公开(公告)日：2022-11-24
申请号：PCT/IB2022/054586
申请日：2022-05-17
申请人： ION HEAT SAS
发明人： BERNAL, Andres , RENDÓN, Juan David , ISAZA, Juan Daniel
IPC分类号： A61B5/08 , A61B5/087 , A61B5/00
摘要： The present disclosure relates to a monitoring device for measuring and monitoring breathing parameters and, optionally, oxygenation and/or vital sign parameters of a patient, the monitoring device being removably arrangeable at a portion of a device in fluid connection with an airway of the patient. The monitoring device comprises a first sensor arrangeable at the fluid connection for measuring parameters related to an airflow in the fluid connection to obtain measurement data; a processor adapted to receive the measurement data from the first sensor and configured to process the measurement data into at least one breathing parameter; and a transmitter adapted to transmit data comprising the at least one breathing parameter to an external device. The disclosure further relates to a system and method for measuring and monitoring breathing parameters and, optionally, oxygenation and/or vital sign parameters of a patient. The monitoring device, system, and method allow remote monitoring of breathing parameters of a patient.

5. 发明申请

WO2022209847A1 口腔挿入具及び睡眠時無呼吸症候群の有無を検出するためのキット审中-公开
公开(公告)号：WO2022209847A1
公开(公告)日：2022-10-06
申请号：PCT/JP2022/011570
申请日：2022-03-15
申请人：帝人ファーマ株式会社
发明人：中村　俊貴 , 原田　雄樹
IPC分类号： A61B5/087
摘要：【課題】ＮＥＰ法（ＮｅｇａｔｉｖｅＥｘｐｉｒａｔｏｒｙＰｒｅｓｓｕｒｅ法）において、精度よく閉塞性睡眠時無呼吸症候群の有無を検出するために用いる口腔挿入具の提供。【解決手段】ユーザーの口腔に挿入される口腔挿入具であって、筒状のベース部であって、前記ベース部を貫通する空気口部を有する前記ベース部と、前記ベース部の端から長軸方向に延伸する延伸部であって、前記延伸部の一部にスリットを有する前記延伸部と、を有することを特徴とする、口腔挿入具。

6. 发明申请

WO2022189814A1 TRIBOELECTRIC RESPIRATION MONITORING SENSOR AND A FACE MASK COMPRISING SUCH A TRIBOELECTRIC RESPIRATION MONITORING SENSOR 审中-公开
公开(公告)号：WO2022189814A1
公开(公告)日：2022-09-15
申请号：PCT/HU2022/050021
申请日：2022-03-08
申请人： BUDAPESTI MŰSZAKI ÉS GAZDASÁGTUDOMÁNYI EGYETEM
发明人： HE, Haijun , GUO, Jian , MOLNÁR, DR., Kolos
IPC分类号： A61B5/08 , A61B5/087 , A61B5/00
摘要： The present invention relates to a triboelectric respiration monitoring sensor (10), comprising first and second flat electrodes (12, 14) arranged opposite each other and at a fixed distance from each other, in said first electrode (12) one or more air permeable openings (12a) are formed, and a triboelectric nanofiber layer (44) is arranged on the side of the second electrode (14) facing the first electrode (12), and a flexible triboelectric nanofiber membrane (42) is attached to the first electrode (12) in a manner that allows the membrane (42) to deflect in the direction of the electrodes (12, 14) and contact the nanofiber layer (44). The invention further relates to a face mask (100) comprising a triboelectric respiration monitoring sensor (10) according to the invention.

7. 发明申请

WO2022189429A1 METHOD FOR DETERMINING RESPIRATORY TIMING PARAMETERS FROM RESPIRATORY MONITORING MEASUREMENTS OF A SUBJECT 审中-公开
公开(公告)号：WO2022189429A1
公开(公告)日：2022-09-15
申请号：PCT/EP2022/055887
申请日：2022-03-08
申请人： ONERA TECHNOLOGIES B.V.
发明人： ROSSI, Alessandro , SCHNEIDER, Hartmut
IPC分类号： A61B5/08 , A61B5/00 , A61B5/087
摘要： The present disclosure relates to a method (M0) for providing respiratory timing parameters from respiratory monitoring measurements of a subject, the method comprising the steps of: providing (M1) a respiratory effort signal (E) and a respiratory flow signal (F) of a subject; determining (M2a) an ensemble of peaks (pE) in the respiratory effort signal (E) and determining (M2b) an ensemble of valleys (vE) in the respiratory effort signal (E); and identifying (M3) times associated with the valleys (vE) as preliminary inspiratory onset times (t'io); refining (M4) preliminary inspiratory onset times (t'io) within respective peak-to-peak time intervals (Tpp) of the respiratory effort signal (E) by: determining (M41) first derivative (F1d) of the respiratory flow signal (F) in a respective peak-to-peak interval (Tpp); determining (M42) local peaks (pF1d) and valleys (vF1d) in the respiratory flow signal first derivative (F1d); determining (M43) a time midpoint (tmid) between the time of a local valley (vF1d) in the respiratory flow signal first derivative (F1d) closest in time to the later endpoint in the respective peak-to-peak time interval (Tpp) and the time of a local peak (pF1d) in the respiratory flow signal derivative (F1d) in the respective peak-to-peak time interval (Tpp); evaluating (M44) whether the respiratory effort signal (E) at the determinedtime midpoint (tmid) satisfies a predetermined inspiratory onset time condition, and if satisfied, selecting (M45) the determined time midpoint (tmid) as an inspiratory onset time (tio) instead of the preliminary inspiratory onset time (t'io) for that peak-to-peak interval (Tpp), whereas if the condition is not satisfied, keep the preliminary inspiratory onset time as the inspiratory onset time for that peak-to-peak interval.

8. 发明申请

WO2022144178A1 GENERATING A MODEL OF THE AIRWAY OF A SLEEPING SUBJECT 审中-公开
公开(公告)号：WO2022144178A1
公开(公告)日：2022-07-07
申请号：PCT/EP2021/086052
申请日：2021-12-16
申请人： KONINKLIJKE PHILIPS N.V.
发明人： KAHLERT, Joachim, Johannes , DOS SANTOS DA FONSECA, Pedro, Miguel, Ferreira , WILLARD, Nicolaas, Petrus , GRASSI, Angela
IPC分类号： A61B5/113 , A61B5/00 , A61B5/087
摘要： A system and method for generating a non-linear model of the airway of a sleeping subject is provided. The system comprises an interface adapted to obtain an airway model configured to represent respiratory airflow in the airway of the subject; a movement sensor arrangement configured to detect movement of the chest or abdomen of a subject; an airflow sensor arrangement configured to detect an airflow in the airway of the subject; and a processor arrangement. The processor arrangement is configured to determine a movement pattern from detected movement of the chest or abdomen of the subject; determine an airflow pattern from detected airflow in the airway of the subject and modify the airway model based on the movement pattern and the airflow pattern so as to generate a subject-specific piecewise linearized non-linear airway model for the subject representing respiratory airflow in the airway of the subject in a sleep state. The system may be used for patient stratification and sleep apnea therapy selection, wherein sleep apnea therapy selection covers the primary selection of a single or combination therapy, as well as the dynamic adaption of the selected therapies during sleep.

9. 发明申请

WO2022139256A1 폐용적신호의 변화를 통한 비정상 호흡 검출 장치 및 그 방법 审中-公开
公开(公告)号：WO2022139256A1
公开(公告)日：2022-06-30
申请号：PCT/KR2021/018474
申请日：2021-12-07
申请人： 주식회사 바이랩
发明人： 장극영 , 위헌
IPC分类号： A61B5/08 , A61B5/087 , A61B5/00
摘要： 본 발명은 폐용적신호의 변화를 통한 비정상 호흡 검출 장치 및 그 방법에 관한 것으로, 피검자로부터 획득한 폐용적신호의 변화를 이용하여 비정상적인 멀티 호흡 이벤트, 비정상적인 호흡 주기를 가지는 단일 호흡 이벤트 또는 이들의 조합을 검출하여, 상기 피검자에 대한 무호흡(Apnea), 저호흡(Hypopnea), 서호흡(Bradypnea) 및 흡기시 호흡 정지(Inspiratory Breath Hold)를 포함하는 복수의 비정상 호흡을 검출하는 장치 및 방법에 관한 것이다.

10. 发明申请

WO2022139005A1 호흡훈련 시스템 및 이에 포함되는 호흡측정장치 审中-公开
公开(公告)号：WO2022139005A1
公开(公告)日：2022-06-30
申请号：PCT/KR2020/018856
申请日：2020-12-22
申请人： 주식회사 프로젝트레인보우
发明人： 홍장택
IPC分类号： A61B5/087 , A61B5/08 , A63B23/18 , A63B71/06 , G16H20/30 , A61B5/00
摘要： 본 발명은 사용자에게 호흡훈련 컨텐츠를 제공하는 호흡훈련 시스템에 관한 것이다. 상기 호흡훈련 시스템은, 상기 호흡훈련 컨텐츠를 표시하는 디스플레이장치, 상기 사용자의 호흡이 인가되는 유로부의 내부압력에 대한 호흡정보, 및 상기 유로부의 위치변화에 대한 위치변화정보를 측정하는 호흡측정장치 및 상기 측정 데이터를 수신하고, 상기 측정 데이터를 기초로 상기 호흡훈련 컨텐츠의 동작을 제어하는 제어장치를 포함하되, 상기 제어장치는, 상기 위치변화정보를 기초로, 상기 호흡훈련 컨텐츠 내에 포함된 포인터의 위치를 변경하고, 상기 호흡정보를 기초로, 상기 포인터에 대한 입력을 수행하는 것을 포함한다.

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