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1. 发明申请

WO2020049436A1 A METHOD FOR THE PREPARATION OF FLUOROALKYL NITRILES AND THEIR USE TO PREPARE RELATED FLUOROALKYL TETRAZOLES 审中-公开
公开(公告)号：WO2020049436A1
公开(公告)日：2020-03-12
申请号：PCT/IB2019/057377
申请日：2019-09-02
申请人： PI INDUSTRIES LTD.
发明人： KARRI, Phaneendrasai , PABBA, Jagadish , GURJAR, Bhagwan Lal , KLAUSENER, Alexander G.M.
IPC分类号： C07C253/20 , C07C255/10 , C07D257/04
摘要： The present invention relates to a method for the preparation of fluoroalkyl nitrile of Formula I and their use to prepare related fluoroalkyl tetrazole of Formula II in the presence of the dehydrating agent, wherein, x 1 and x 2 have the same meaning as defined in the description. The present invention also relates to an apparatus for the preparation of fluoroalkyl nitrile of Formula I and fluoroalkyl tetrazole of Formula II.

2. 发明申请

WO2007147888A1 MALONONITRILE COMPOUNDS 审中-公开
标题翻译：马来酸化合物
公开(公告)号：WO2007147888A1
公开(公告)日：2007-12-27
申请号：PCT/EP2007/056249
申请日：2007-06-22
申请人： BASF AKTIENGESELLSCHAFT , POHLMANN, Matthias , HOFMANN, Michael , BASTIAANS, Henricus Maria Martinus , RACK, Michael , CULBERTSON, Deborah L. , OLOUMI-SADEGHI, Hassan , HOKAMA, Takeo , PALMER, Christopher
发明人： POHLMANN, Matthias , HOFMANN, Michael , BASTIAANS, Henricus Maria Martinus , RACK, Michael , CULBERTSON, Deborah L. , OLOUMI-SADEGHI, Hassan , HOKAMA, Takeo , PALMER, Christopher
IPC分类号： C07C255/10 , A01N37/34
CPC分类号： C07C255/10 , A01N37/34 , A01N47/02 , C07C255/13 , C07C317/44 , C07C323/60 , C07C2601/14
摘要： Compounds of formula (I) wherein the symbols have the meaning given in the specification, as well as processes for preparing the compounds (I), pesticidal compositions and synergistic mixtures comprising compounds (I), methods for the control of insects, acarids or nematodes by contacting the pests or their food supply, habitat or breeding grounds with a pesticidally effective amount of compounds formula (I), and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites which comprises orally, topically or parenterally administering or applying to the animals a parasiticidally effective amount of compounds of formula (I).
摘要翻译：式（I）化合物，其中符号具有说明书中给出的含义，以及制备化合物（I），杀虫组合物和包含化合物（I）的协同混合物的方法，用于防治昆虫，螨虫或线虫的方法通过将害虫或其食物供应，栖息地或繁殖地与农药有效量的化合物（I）接触，以及用于治疗，控制，预防或保护动物免受寄生虫感染或侵袭的方法，其包括口服，局部或肠胃外给予动物杀虫剂有效量的式（I）化合物。

3. 发明申请

WO9829358A3 SURFACE MODIFIED CARBONATE MATERIALS 审中-公开
标题翻译：表面改性碳酸盐材料
公开(公告)号：WO9829358A3
公开(公告)日：1998-10-08
申请号：PCT/CA9701008
申请日：1997-12-30
申请人： HYDRO QUEBEC , CENTRE NAT RECH SCIENT , MICHOT CHRISTOPHE , ARMAND MICHEL , GAUTHIER MICHEL , CHOQUETTE YVES
发明人： MICHOT CHRISTOPHE , ARMAND MICHEL , GAUTHIER MICHEL , CHOQUETTE YVES
IPC分类号： C07D233/58 , B01F1/00 , B01J31/02 , B01J31/04 , B01J31/06 , B01J31/12 , B01J31/18 , B01J31/22 , C01B31/02 , C04B41/83 , C07B37/02 , C07B37/12 , C07B41/06 , C07B61/00 , C07C45/46 , C07C45/69 , C07C67/00 , C07C255/05 , C07C255/10 , C07C255/13 , C07C255/17 , C07C255/27 , C07C255/31 , C07C255/46 , C07C255/65 , C07C257/14 , C07C309/80 , C07C311/03 , C07C311/04 , C07C311/09 , C07C311/48 , C07C317/04 , C07C317/08 , C07C317/14 , C07C317/22 , C07C317/24 , C07C317/34 , C07C317/44 , C07D207/44 , C07D207/452 , C07D213/76 , C07D219/10 , C07D231/18 , C07D233/56 , C07D233/90 , C07D239/60 , C07D241/46 , C07D241/48 , C07D249/04 , C07D249/08 , C07D249/10 , C07D249/12 , C07D251/66 , C07D251/70 , C07D253/06 , C07D277/64 , C07D277/82 , C07D279/20 , C07D285/00 , C07D285/12 , C07D285/125 , C07D285/135 , C07D285/15 , C07D285/16 , C07D303/34 , C07D303/36 , C07D307/54 , C07D307/64 , C07D311/52 , C07D311/58 , C07D311/72 , C07D311/80 , C07D311/82 , C07D319/06 , C07D333/16 , C07D333/20 , C07D333/24 , C07D405/06 , C07D407/04 , C07D409/12 , C07D417/10 , C07D417/14 , C07D487/22 , C07F1/02 , C07F1/06 , C07F7/10 , C07F7/18 , C07F9/6584 , C07F11/00 , C07F15/00 , C07F17/02 , C08F2/00 , C08F2/48 , C08F4/00 , C08F4/04 , C08F4/46 , C08F4/60 , C08F12/22 , C08F12/26 , C08F12/30 , C08F16/14 , C08F216/14 , C08F222/30 , C08F228/02 , C08G59/68 , C08G65/22 , C08G65/334 , C08G73/00 , C08G73/02 , C08G75/00 , C08G75/14 , C08G77/04 , C08G77/388 , C08G85/00 , C08J3/20 , C08J3/24 , C08J3/28 , C08J7/04 , C08L101/00 , C09B47/04 , C09B57/00 , C09B69/00 , C09B69/02 , C09B69/10 , C09C1/56 , C09C3/10 , C09D11/00 , C09K9/02 , C25B9/00 , G02F1/15 , H01B1/04 , H01B1/06 , H01B1/12 , H01B3/20 , H01G9/02 , H01G11/54 , H01M4/00 , H01M4/02 , H01M4/131 , H01M4/133 , H01M4/134 , H01M4/40 , H01M4/48 , H01M4/485 , H01M4/50 , H01M4/505 , H01M4/52 , H01M4/525 , H01M4/58 , H01M4/60 , H01M4/62 , H01M4/66 , H01M4/96 , H01M6/00 , H01M6/04 , H01M6/06 , H01M6/16 , H01M6/18 , H01M8/00 , H01M10/052 , H01M10/0525 , H01M10/0565 , H01M10/0567 , H01M10/0568 , H01M10/36 , C04B41/00
CPC分类号： B01J31/0224 , B01J31/0215 , B01J31/0222 , B01J31/0225 , B01J31/0227 , B01J31/0235 , B01J31/0239 , B01J31/0247 , B01J31/0251 , B01J31/0252 , B01J31/0267 , B01J31/0271 , B01J31/0281 , B01J31/0288 , B01J31/0289 , B01J31/04 , B01J31/06 , B01J31/068 , B01J31/124 , B01J31/1815 , B01J31/2208 , B01J2231/122 , B01J2231/14 , B01J2231/326 , B01J2231/341 , B01J2231/348 , B01J2231/4205 , B01J2231/543 , B01J2531/35 , B01J2531/824 , C07B37/02 , C07B37/12 , C07C45/46 , C07C45/69 , C07C67/00 , C07C255/10 , C07C255/17 , C07C255/27 , C07C255/46 , C07C255/65 , C07C257/14 , C07C311/03 , C07C311/04 , C07C311/09 , C07C311/48 , C07C317/04 , C07C317/08 , C07C317/14 , C07C317/22 , C07C317/24 , C07C317/34 , C07C317/44 , C07C2601/10 , C07C2602/42 , C07D207/452 , C07D213/76 , C07D219/10 , C07D231/18 , C07D233/90 , C07D239/60 , C07D241/42 , C07D249/04 , C07D249/10 , C07D249/12 , C07D251/70 , C07D277/64 , C07D277/82 , C07D285/125 , C07D285/135 , C07D285/15 , C07D285/16 , C07D303/34 , C07D307/54 , C07D307/64 , C07D311/52 , C07D311/58 , C07D311/82 , C07D319/06 , C07D333/16 , C07D333/24 , C07D405/06 , C07D409/12 , C07D417/10 , C07D417/14 , C07F17/02 , C08F4/04 , C08G65/3344 , C09B69/00 , C09B69/02 , C09B69/10 , G02F1/1525 , G02F2001/151 , H01B1/122 , H01B1/128 , H01G9/022 , H01G9/038 , H01G11/02 , H01G11/62 , H01M4/00 , H01M4/02 , H01M4/131 , H01M4/133 , H01M4/134 , H01M4/382 , H01M4/405 , H01M4/48 , H01M4/485 , H01M4/505 , H01M4/525 , H01M4/5815 , H01M4/5825 , H01M4/60 , H01M4/625 , H01M4/661 , H01M6/00 , H01M6/04 , H01M6/164 , H01M6/166 , H01M6/168 , H01M6/181 , H01M6/183 , H01M10/052 , H01M10/0525 , H01M10/0565 , H01M10/0567 , H01M10/0568 , Y02E60/13 , Y10S430/127 , Y10T29/49108 , Y10T428/2918 , C07C49/84 , C07C49/553
摘要： Battery has an electrolyte comprising a solvent and a salt (I) comprising a hydroxonium, nitrosonium, ammonium, metal, organic or organometallic cation and a 5-membered (hetero)cyclic anion. Battery has an electrolyte comprising a solvent and a salt (I) comprising a hydroxonium, nitrosonium, ammonium, metal, organic or organometallic cation and a 5-membered (hetero)cyclic anion with the following formula: [Image] X1-X5-N=, -N->-, -C(Y)=, -C->(Y)-, -S(O)(Q)=, -S(Q)= or -P(Q')(Q)=, provided that no more than four comprise N, no more than two comprise S (nonadjacent) and no more than one comprises P; Q', Q : 1-8C perhaloalkyl, perhaloalkenyl or optionally substituted 6-12C aryl or aralkyl, each optionally containing O, S or N heteroatoms; Q : an alkyl, alkenyl, aryl, aralkyl, alkylaryl, alkenylaryl, alicyclic or heterocyclic group optionally substituted with halogen and/or ether, thioether, amine, imine, amide, carboxy, carbonyl, isocyanate, isothiocyanate and hydroxy groups; an aromatic group with ring(s) and/or substituent(s) containing heteroatoms; a polymeric group; or a group having one or more cationic and/or anionic ionophore groups; Y : H, F, Cl, Br, CN, SCN, NCS, NCO, NO2, perfluoroalkyl, perfluoroalkoxy, perfluoroalkylmethyl, tetrafluoroethoxy, SCF3, perfluoroalkylthio, tetrafluoroethylthio, trifluorovinyloxy, trifluorovinylthio, SO2F, SO2Q, COOQ, Q-N-SO2- (sic) or COQ; a group comprising one or more aromatic rings that optionally contain N, O, S or P and are optionally substituted with halogen, CN, CO2, SCN, N3, trifluorovinyloxy, (1-12C perfluoroalkyl)methyl, fluoroalkoxy, fluoroalkylthioxy, alkyl, alkenyl, oxaalkyl, oxaalkenyl, azaalkyl, azaalkenyl, thiaalkyl, thiaalkenyl, polymeric groups and groups having one or more cationic and/or anionic ionophore groups; alternatively, two of Y, Q, Q' and Q can form a 4- to 8-membered ring, or one of Y and Q is a multivalent group attached to a second 5-membered (hetero)cyclic anion, or one of Y and Q is a repeat unit of a polymer; provided that at least one Y or Q comprises a dissociating dipole.

4. 发明申请

WO2022028941A1 A PROCESS FOR PREPARATION OF OXAZOLE COMPOUNDS 审中-公开
公开(公告)号：WO2022028941A1
公开(公告)日：2022-02-10
申请号：PCT/EP2021/070913
申请日：2021-07-27
申请人： DSM IP ASSETS B.V.
发明人： BONRATH, Werner , DAI, Le , DAI, Xixiang , LIU, Qiangqiang , PENG, Kun , STEMMLER, René Tobias , WU, Liuhai , ZHANG, Lei
IPC分类号： C07D263/34 , C07C255/10
摘要： The present invention provides a new process for producing an oxazole compound of formula (I), which can avoid toxic and corrosive reagent, and salts by-products and has high efficiency,formula (I). Wherein R is H, or lower alkyl or aryl optionally substituted by one or more substituents.

5. 发明申请

WO2021149051A1 COMPOSITIONS FOR CROP PROTECTION 审中-公开
公开(公告)号：WO2021149051A1
公开(公告)日：2021-07-29
申请号：PCT/IL2021/050062
申请日：2021-01-20
申请人： AGREMATCH LTD.
发明人： SHUB, Ifat , PHILLIP, Yael , GEVA, Yosef
IPC分类号： A01N37/20 , A01N37/34 , C07D207/337 , C07D213/56 , C07D231/40 , C07D233/66 , C07D277/46 , C07D307/54 , C07D333/26 , C07D309/34 , C07C233/05 , C07C233/09 , C07C233/13 , C07C233/20 , C07C255/02 , C07C255/10 , C07C255/29
摘要： The present invention provides compounds and herbicidal compositions comprising thereof. Further, use of herbicidal compositions or kit for controlling plant growth is also provided.

6. 发明申请

WO2014202765A1 PREPARATION OF CHIRAL 1-METHYL-2,3,4,5-1H-BENZODIAZEPINES VIA ASYMMETRIC REDUCTION OF ALPHA-SUBSTITUTED STYRENES 审中-公开
标题翻译：通过不对称还原ALPHA取代的苯乙烯制备正丙-1-甲基-2,3,4,5-1H-苯并二氮杂
公开(公告)号：WO2014202765A1
公开(公告)日：2014-12-24
申请号：PCT/EP2014/063048
申请日：2014-06-20
申请人： LEK PHARMACEUTICALS D.D.
发明人： STAVBER, Gaj , GAZIC SMILOVIC, Ivana , CLUZEAU, Jerome , RICHTER, Frank
IPC分类号： C07D223/16 , C07C67/03 , C07C69/635 , C07C201/12 , C07C205/09 , C07C209/34 , C07C209/48 , C07C211/29 , C07C217/40 , C07C233/18 , C07C253/30 , C07C255/10 , C07C311/17
CPC分类号： C07D223/16 , C07B53/00 , C07B2200/07 , C07C67/303 , C07C69/65 , C07C201/12 , C07C211/29 , C07C217/40 , C07C233/18 , C07C253/30 , C07C255/35 , C07C311/17 , C12P7/62 , C12P13/002 , C12P13/008 , C12P41/002 , C07C205/09
摘要： The present invention provides an asymmetric and economic synthesis of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1 H-benzo[d]azepine via novel intermediates applying an asymmetric enzymatic, biomimetic or catalytic reduction. The present invention also provides a novel green asymmetric catalytic reduction adapted for an aqueous medium to be applied in the synthesis of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1 H-benzo[d]azepine or novel intermediates.
摘要翻译：本发明通过应用不对称的酶，仿生或催化还原的新型中间体提供8-氯-1-甲基-2,3,4,5-四氢-1H-苯并[d]氮杂的不对称和经济合成。本发明还提供适用于合成8-氯-1-甲基-2,3,4,5-四氢-1H-苯并[d]吖庚因的水性介质的新颖的绿色不对称催化还原或新颖的中间体。

7. 发明申请

WO2021077194A1 PROCESSO PARA OBTENÇÃO DE COMPOSIÇÕES FARMACÊUTICAS ANTITUMORAIS ATRAVÉS DE BUTADIENOS PUSH-PULL, COMPOSTOS E SEUS USOS 审中-公开
公开(公告)号：WO2021077194A1
公开(公告)日：2021-04-29
申请号：PCT/BR2020/050437
申请日：2020-10-23
申请人： ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A , FUNDAÇÃO UNIVERSIDADE FEDERAL DO ABC , INSTITUTO BUTANTAN
发明人： ORZARI RIBEIRO, Anderson , PASSARELLI GONÇALVES, Carolina , AUGUSTO MARIA, Durvanei , QUINCOCES SUÁREZ, José Agustín , SALUSTIANO ALMEIDA SAAVEDRA, Manuel
IPC分类号： C07C323/16 , C07C255/10 , C07C255/38 , C07C255/40 , C07C205/09 , C07C205/42 , C07C49/235 , C07C49/248 , A61C31/10 , A61K31/277 , A61K31/04 , A61K31/12 , A61P35/00 , A61P35/04
摘要： A presente invenção relata a obtenção de compostos carbonílicos e derivados, através de sínteses com alto rendimento e pureza, proporcionando princípios ativos antitumorais com propriedades antiproliferativas seletivas e atividade antimetastática. A presente invenção refere-se ao desenvolvimento de novos butadienos push-pull polifuncionais e seus derivados O e C-prenilados, benzoilados e iodados, com alta conjugação eletrônica na cadeia lateral. Estes compostos exibem alta seletividade antitumoral, provocando a morte celular por apoptose, mostram também propriedades antimetastáticas e não mutagênicas nos estudos experimentais realizados.

8. 发明申请

WO2017040518A1 NITROGEN-CONTAINING COMPOUNDS FOR ETCHING SEMICONDUCTOR STRUCTURES 审中-公开
标题翻译：用于蚀刻半导体结构的含氮化合物
公开(公告)号：WO2017040518A1
公开(公告)日：2017-03-09
申请号：PCT/US2016/049479
申请日：2016-08-30
申请人： L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE , AMERICAN AIR LIQUIDE, INC. , SURLA, Vijay , GUPTA, Rahul , PALLEM, Venkateswara R.
发明人： SURLA, Vijay , GUPTA, Rahul , PALLEM, Venkateswara R.
IPC分类号： H01L21/311 , C07C251/08 , C07C251/26 , C07C255/10
CPC分类号： H01L21/31116 , C07C251/08 , C07C251/26 , C07C255/10 , H01L21/31144
摘要： A method for etching silicon-containing films is disclosed. The method includes the steps of introducing a vapor of a nitrogen containing etching compound into a reaction chamber containing a silicon-containing film on a substrate, wherein the nitrogen containing etching compound is an organofluorine compound containing at least one C≡N or C=N functional group; introducing an inert gas into the reaction chamber; and activating a plasma to produce an activated nitrogen containing etching compound capable of etching the silicon-containing film from the substrate.
摘要翻译：公开了一种用于蚀刻含硅膜的方法。该方法包括以下步骤：将含氮蚀刻化合物的蒸气引入到含有含硅膜的反应室中，其中含氮蚀刻化合物是含有至少一个C≡N或C = N的有机氟化合物功能组将惰性气体引入反应室; 并激活等离子体以产生能够从衬底上蚀刻含硅膜的活性含氮蚀刻化合物。

9. 发明申请

WO2004105929A3 PHASE TRANSFER CATALYSIS SCRUBBER 审中-公开
标题翻译：相转移催化剂
公开(公告)号：WO2004105929A3
公开(公告)日：2005-05-06
申请号：PCT/US2004016348
申请日：2004-05-25
申请人： VALUE RECOVERY INC
发明人： JOYCE PETER J , BIELSKI ROMAN , BUCKMASTER TERRENCE P , HALPERN MARC
IPC分类号： B01D53/14 , B01D53/70 , B01J20060101 , B01J31/02 , C07C17/395 , C07C19/00 , C07C41/16 , C07C43/205 , C07C67/10 , C07C67/11 , C07C67/31 , C07C253/14 , C07C255/04 , C07C255/10 , C07C255/33 , C07C255/40 , C07C331/04
CPC分类号： C07C17/395 , B01D53/1487 , B01D53/70 , B01J31/0235 , C07C41/16 , C07C67/10 , C07C67/11 , C07C67/31 , C07C253/14 , C07C331/04 , C07C19/075 , C07C255/04 , C07C255/10 , C07C255/33 , C07C255/40 , C07C43/205 , C07C43/2055
摘要： A method and system for reactively destroying alkyl halides in volume or stream of gas. The method and device employ nucleophilic reaction of the alkyl halide under phase transfer catalysis conditions. The method and system are useful for scrubbing applications requiring the reduction of alkyl halide concentrations to very low levels.
摘要翻译：用于在体积或气体流中反应性地破坏卤代烷的方法和系统。该方法和装置在相转移催化条件下使用烷基卤的亲核反应。该方法和系统可用于洗涤需要将烷基卤浓度降低到非常低水平的应用。

10. 发明申请

WO0200608A3 A PROCESS FOR THE PREPARATION OF 2,2-DIMETHYL-5-(4-CHLOROBENZYL) CYCLOPENTANONE AND AN INTERMEDIATE USEFUL THEREFOR 审中-公开
标题翻译：制备2,2-二甲基-5-（4-氯苄基）环戊酮的方法及其中间体有用的方法
公开(公告)号：WO0200608A3
公开(公告)日：2002-05-30
申请号：PCT/EP0106578
申请日：2001-06-11
申请人： BASF AG
发明人： WONG GEORGE S K
IPC分类号： C07C45/65 , C07B61/00 , C07C45/67 , C07C49/697 , C07C253/30 , C07C255/04 , C07C255/10 , C07C255/46 , C07C253/00
CPC分类号： C07C255/46 , C07C45/673 , C07C49/697 , C07C2601/08
摘要： A process for the preparation of 2,2-dimethyl-5-(4-chlorobenzyl)cyclopentanone (I) by reaction isobutyronitrile with 1-bromo-3-chloropropane in the presence of a first base in a non-polar solvent to afford 5-chloro-2,2-dimethylpentanenitrile; treating said 5-chloro-2,2-dimethylpentanenitrile with a cyanide-delivering reagent in the presence of a phase-transfer catalyst to form 2,2-dimethyladiponitrile; cyclizing said 2,2-dimethyladiponitrile in the presence of a second base in a non-polar solvent to afford 3,3-dimethyl-2-amino-1-cyanocyclopentene; hydrolyzing said 3,3-dimethyl-2-amino-1-cyanocyclopentene in the presence of an acid to give 5-cyano-2,2-dimethylcyclopentanone; treating said 5-cyano-2,2-dimethylcyclopentanone with 4-chlorobenzyl chloride in the presence of a third base in a polar aprotic solvent to form 5-(4-chorobenzyl)-5-cyano-2,2-dimethylcyclopentanone; and hydrolyzing said 5-(4-chlorobenzyl)-5-cyano-2,2-dimethylcyclopentanone in the presence of an acid to give the desired 5-(4-chlorobenzyl)-2,2-dimethylcyclopentanone; the compound, 5-(4-chlorobenzyl)-5-cyano-2,2-dimethylcyclopentanone.
摘要翻译：通过反应异丁腈与1-溴-3-氯丙烷在非极性溶剂中的第一碱存在下制备2,2-二甲基-5-（4-氯苄基）环戊酮（I）的方法，得到5 氯-2,2-二甲基戊腈; 在相转移催化剂存在下用氰化物递送剂处理所述5-氯-2,2-二甲基戊腈以形成2,2-二甲基己二腈; 在第二碱的存在下在非极性溶剂中使所述2,2-二甲基己二腈环化，得到3,3-二甲基-2-氨基-1-氰基环戊烯; 在酸存在下水解所述3,3-二甲基-2-氨基-1-氰基环戊烯，得到5-氰基-2,2-二甲基环戊酮; 在极性非质子溶剂中在第三碱存在下用4-氯苄基氯处理所述5-氰基-2,2-二甲基环戊酮以形成5-（4-氯苄基）-5-氰基-2,2-二甲基环戊酮; 并在酸存在下水解所述5-（4-氯苄基）-5-氰基-2,2-二甲基环戊酮，得到所需的5-（4-氯苄基）-2,2-二甲基环戊酮; 化合物，5-（4-氯苄基）-5-氰基-2,2-二甲基环戊酮。

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