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首页 / 专利库 / 抗真菌多肽 / 专利数据
序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
61 Antifungal polypeptide and methods for controlling plant pathogenic fungi US10010731 2001-11-13 US20030041347A1 2003-02-27 Jihong Liang; Dilip Maganlal Shah; Yonnie S. Wu; Cindy A. Rosenberger; Salim Hakimi
Antifungal polypeptides, isolated from Medicago plants, are shown to control fungal damage to plants. DNA encoding the polypeptides was cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptides can be formulated into compositions useful in controlling undesired fungi.
62 Antifungal polypeptide and methods for controlling plant pathogenic fungi US09428805 1999-10-28 US06329504B1 2001-12-11 Jihong Liang; Dilip Maganlal Shah; Yonnie S. Wu; Cindy A. Rosenberger; Salim Hakimi
Antifungal polypeptides, isolated from Medicago plants, are shown to control fungal damage to plants. DNA encoding the polypeptides was cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptides can be formulated into compositions useful in controlling undesired fungi.
63 Antifungal polypeptide and methods for controlling plant pathogenic fungi US10681972 2003-10-09 US20040064850A1 2004-04-01 Jihong Liang; Dilip Maganlal Shah; Yonnie Shun Wu; Cindy Annette Rosenberger
An antifungal polypeptide, AlyAFP, that controls fungal damage to plants is provided. DNA encoding this polypeptide can be cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptide can be formulated into compositions that can be used to control undesired fingi on plants and elsewhere.
64 Antifungal polypeptide and methods for controlling plant pathogenic fungi US09829381 2001-04-09 US20020144306A1 2002-10-03 Jihong Liang; Dilip Maganlal Shah; Yonnie Shun Wu; Cindy Annette Rosenberger
An antifungal polypeptide, AlyAFP, that controls fungal damage to plants is provided. DNA encoding this polypeptide can be cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptide can be formulated into compositions that can be used to control undesired fungi on plants and elsewhere.
65 ANTIMICROBIAL POLYPEPTIDE FROM THE FUNGUS COPRINOPSIS CINEREA PCT/EP2014/072444 2014-10-20 WO2015059095A1 2015-04-30 AEBI, Markus; WIDER, Gerhard; KÜNZLER, Markus; ESSIG, Andreas; HOFMANN, Daniela

The present invention relates to new antimicrobial polypeptides, nucleic acids encoding them, as well as recombinant vectors, host cells, antibodies, uses and methods relating thereto.

66 ANTIFUNGAL POLYPEPTIDE AND METHODS FOR CONTROLLING PLANT PATHOGENIC FUNGI PCT/US9705709 1997-03-27 WO9737024A3 1998-02-19 LIANG JIHONG; SHAH DILIP MAGANLAL; WU YONNIE SHUN; ROSENBERGER CINDY ANNETTE
An antifungal polypeptide, AlyAFP, that controls fungal damage to plants is provided. DNA encoding this polypeptide can be cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptide can be formulated into compositions that can be used to control undesired fungi on plants and elsewhere.
67 ANTIFUNGAL POLYPEPTIDE AND METHODS FOR CONTROLLING PLANT PATHOGENIC FUNGI PCT/US1997005709 1997-03-27 WO1997037024A2 1997-10-09 MONSANTO COMPANY; LIANG, Jihong; SHAH, Dilip, Maganlal; WU, Yonnie, Shun; ROSENBERGER, Cindy, Annette
An antifungal polypeptide, AlyAFP, that controls fungal damage to plants is provided. DNA encoding this polypeptide can be cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptide can be formulated into compositions that can be used to control undesired fungi on plants and elsewhere.
68 ANTIFUNGAL POLYPEPTIDE AND METHODS FOR CONTROLLING PLANT PATHOGENIC FUNGI PCT/US1997022662 1997-12-11 WO1998026083A1 1998-06-18 MONSANTO COMPANY; LIANG, Jihong; SHAH, Dilip, M.; WU, Yonnie, S.; ROSENBERGER, Cindy, A.; HAKIMI, Salim
Antifungal polypeptides, isolated from Medicago plants, are shown to control fungal damage to plants. DNA encoding the polypeptides was cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptides can be formulated into compositions useful in controlling undesired fungi.
69 ANTIFUNGISCHES POLYPEPTID, VERFAHREN ZU SEINER HERSTELLUNG EP91911239.0 1991-06-12 EP0535060A1 1993-04-07 ULBRICH, Norbert; HILGENFELD, Rolf; HÄNEL, Heinz; SACHSE, Burkhard; BRAUN, Peter; WINK, Joachim; ECKES, Peter; LOGEMANN, Jürgen; SCHELL, Jozef
Le polypeptide ayant la séquence: Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp-Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln-Ser-Gly-Lys-Thr-Ala-Ile-Cys-Lys-Cys-Tyr-Val-Lys-Lys-Cys-Pro-Arg-Asp-Gly-Ala-Lys-Cys-Glu-Phe-Asp-Ser-Tyr-Lys-Gly-Lys-Cys-Tyr-Cys peut être produit par fermentation d'Aspergillus giganteus et est utile comme fongicide. L'expression de ce gène polypeptidique dans des plantes permet d'inhiber fortement la croissance de champignons phytopathogènes sur la plante.
70 ANTIFUNGISCHES POLYPEPTID, VERFAHREN ZU SEINER HERSTELLUNG EP91911239.1 1991-06-12 EP0535060B1 1995-02-22 ULBRICH, Norbert; HILGENFELD, Rolf; HÄNEL, Heinz; SACHSE, Burkhard; BRAUN, Peter; WINK, Joachim; ECKES, Peter; LOGEMANN, Jürgen; SCHELL, Jozef
A polypeptide with the sequence: Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp-Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln-Ser-Gly-Lys-Thr-Ala-Ile-Cys-Lys-Cys-Tyr-Val-Lys-Lys-Cys-Pro-Arg-Asp-Gly-Ala-Lys-Cys-Glu-Phe-Asp-Ser-Tyr-Lys-Gly-Lys-Cys-Tyr-Cys can be produced by fermentation of Aspergillus giganteus and used as an antifungal agent. Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathological fungi on the plants.
71 Nucleic acids encoding antifungal polypeptides and uses thereof US12503952 2009-07-16 US07825294B2 2010-11-02 Daniel J. Altier; I. A. Ellanskaya; Jacob T. Gilliam; Jennie Hunter-Cevera; James K Presnail; Eric Schepers; Carl R. Simmons; Tamas Torok; Nasser Yalpani
Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include an amino acid sequence, and variants and fragments thereof, for an antipathogenic polypeptide that was isolated from a fungal fermentation broth. Nucleic acid molecules that encode the antipathogenic polypeptides of the invention, and antipathogenic domains thereof, are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention are also disclosed.
72 POLYCLONAL ANTIBODIES TO CLONED FUNGAL POLYPEPTIDE TARGETS US14028670 2013-09-17 US20140113317A1 2014-04-24 Hari M. Vijay
Described herein are processes for preparing a polyclonal antibody which specifically binds to a cDNA derived fungal allergen. Such antibodies, for example, polyclonal antibodies specific for cloned Alt a1 protein from A. alternata or the cloned allergen Ch 2.1 of C. herbarum, can be used in assays and kits for detecting allergens in house-hold dust.
73 ANTI-DANDRUFF COMPOSITION COMPRISING AN ANTIFUNGAL POLYPEPTIDE EP99972925.4 1999-11-26 EP1143995A1 2001-10-17 VIND, Jesper; SORENSEN, Niels Henrik
The present invention relates to an anti-dandruff composition comprising an antifungal polypeptide, to the use of an antifungal polypeptide for the treatment or prophylaxis of dandruff, to a method for the treatment or prophylaxis of dandruff, and to the use of an antifungal polypeptide for the preparation of a composition for the treatment or prophylaxis of dandruff. It has been found that the antifungal polypeptide with the amino acid sequence shown in Fig. 1 efficiently impedes the growth of the yeast P. ovale, even in low concentrations.
74 머리뿔가위벌 유래 항균 및 항진균 활성을 갖는 신규 폴리펩티드 KR1020150150975 2015-10-29 KR1020170049992A 2017-05-11 이경용; 윤형주; 이영보; 김남정
본발명은머리뿔가위벌유래항균및 항진균활성을갖는신규폴리펩티드, 이를코딩하는핵산서열, 상기폴리펩티드를유효성분으로함유하는항균및 항진균용조성물에관한것이다. 본발명에따른머리뿔가위벌유래항균및 항진균활성을갖는신규폴리펩티드는키모트립신, 서브틸리신 A, 프로테아제 K에대한저해활성을통해세균, 병원성곰팡이균과같은미생물의성장을효과적으로억제할수 있는바, 의약품, 세정제, 식물병방제제, 코팅제또는화장품과같은다양한분야의소재로서유용하게사용될수 있다.
75 ANTI-DANDRUFF COMPOSITION COMPRISING AN ANTIFUNGAL POLYPEPTIDE PCT/DK1999/000659 1999-11-26 WO00032220A1 2000-06-08
The present invention relates to an anti-dandruff composition comprising an antifungal polypeptide, to the use of an antifungal polypeptide for the treatment or prophylaxis of dandruff, to a method for the treatment or prophylaxis of dandruff, and to the use of an antifungal polypeptide for the preparation of a composition for the treatment or prophylaxis of dandruff. It has been found that the antifungal polypeptide with the amino acid sequence shown in Fig. 1 efficiently impedes the growth of the yeast P. ovale, even in low concentrations.
76 Antifungal polypeptide from alfalfa and methods for controlling plant pathogenic fungi US09003198 1998-01-07 US06316407B1 2001-11-13 Jihong Liang; Dilip Maganlal Shah; Yonnie S. Wu; Cindy A. Rosenberger; Salim Hakimi
Antifungal polypeptides, isolated from Medicago plants, are shown to control fungal damage to plants. The polypeptides can be formulated into compositions useful in controlling undesired fungi.
77 Antifungal polypeptide AlyAFP from Alyssum and methods for controlling plant pathogenic fungi US09829381 2001-04-09 US06653280B2 2003-11-25 Jihong Liang; Dilip Maganlal Shah; Yonnie Shun Wu; Cindy Annette Rosenberger
An antifungal polypeptide, AlyAFP, that controls fungal damage to plants is provided. DNA encoding this polypeptide can be cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptide can be formulated into compositions that can be used to control undesired fungi on plants and elsewhere.
78 ANTIFUNGAL POLYPEPTIDE AND METHODS FOR CONTROLLING PLANT PATHOGENIC FUNGI EP97920175.0 1997-03-27 EP0904375A2 1999-03-31 LIANG, Jihong; SHAH, Dilip, Maganlal; WU, Yonnie, Shun; ROSENBERGER, Cindy, Annette
An antifungal polypeptide, AlyAFP, that controls fungal damage to plants is provided. DNA encoding this polypeptide can be cloned into vectors for transformation of plant-colonizing microorganisms or plants, thereby providing a method of inhibiting fungal growth on plants. The polypeptide can be formulated into compositions that can be used to control undesired fungi on plants and elsewhere.
79 Immunogenic composition against helicobacter infection, polypeptide for use in the composition, and nucleic acid sequence encoding the polypeptide JP2007252748 2007-09-27 JP2008086316A 2008-04-17 LABIGNE AGNES; SUERBAUM SEBASTIEN; FERRERO RICHARD; THIBERGE JEAN-MICHEL
<P>PROBLEM TO BE SOLVED: To provide an immunogenic composition inducing a protective antibody against Helicobacter infection. <P>SOLUTION: The immunogenic composition comprises (i) at least one subunit of a urease structural polypeptide derived from Helicobacter pylori or its fragment recognizable by antibodies reacting with Helicobacter felis urease and/or at least one subunit of a urease structural polypeptide derived from Helicobacter felis or its fragment recognizable by antibodies reacting with Helicobacter pylori urease and/or (ii) a heat shock protein (HSP), or chaperonin, derived from Helicobacter or a fragment of the protein. The preparation of such immunogenic composition by recombinant means is also provided. <P>COPYRIGHT: (C)2008,JPO&INPIT
80 Antifungal Plant Proteins, Peptides, And Methods Of Use US14888011 2014-04-29 US20160208278A1 2016-07-21 Dilip Shah
Provided are transgenic plants expressing MtDef5 antifungal proteins and peptides exhibiting high levels of resistance to susceptible fungi. Such transgenic plants contain a recombinant DNA construct comprising a natural or heterologous signal peptide sequence operably linked to a nucleic acid sequence encoding these molecules. Also provided are methods of producing such plants, methods of protecting plants against susceptible fungal infection and damage, as well as compositions that can be applied to the locus of plants, comprising microorganisms expressing these molecules, or these molecules themselves, as well as pharmaceutical compositions containing these molecules. Human and veterinary therapeutic use of MtDef5 antifungal proteins and peptides to treat susceptible fungal infections are also encompassed by the invention.