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91. 发明授权

US06273870B1 Retractable needle and syringe combination 有权
标题翻译：伸缩针和注射器组合
公开(公告)号：US06273870B1
公开(公告)日：2001-08-14
申请号：US09575007
申请日：2000-05-19
申请人： David M. Garvin
发明人： David M. Garvin
IPC分类号： A61M500
CPC分类号： A61M5/3234 , A61M5/346 , A61M5/508 , A61M2005/3123 , A61M2005/3235 , A61M2005/3241
摘要： A combination hypodermic syringe and needle device in which the needle is retracted inside the syringe after completion of the injection. The device requires only one hand for operation wherein increasing the pressure on the plunger initiates an automatic retraction of the needle into the syringe. In operation, a collet is expanded and a spring biased needle retractor is engaged in response to the forward movement of a plunger. The forward end of the barrel carries a wedge which forces the collet to expand upon forward movement of the collet. A vent located in the plunger allows air to escape from the interior of the plunger as the needle assembly is retracted.
摘要翻译：组合式皮下注射器和针装置，其中在注射完成之后针在注射器内缩回。该装置仅需要一只手来操作，其中增加柱塞上的压力启动针自动缩回注射器。在操作中，弹簧夹头被膨胀并且响应于柱塞的向前运动而接合弹簧偏压的针牵开器。枪管的前端带有一个楔形件，迫使夹头在夹头向前移动时膨胀。当针组件缩回时，位于柱塞中的通风口允许空气从柱塞的内部逸出。

92. 发明授权

US06270483B1 Liquid discharge regulator and liquid feeder equipped with the same 有权
标题翻译：液体排放调节器和液体送料器配备相同
公开(公告)号：US06270483B1
公开(公告)日：2001-08-07
申请号：US09296536
申请日：1999-04-22
申请人： Keiichi Yamada , Mitsuyoshi Inoue , Hajime Nakazawa , Atsushi Yamamoto , Tatsuji Higashi
发明人： Keiichi Yamada , Mitsuyoshi Inoue , Hajime Nakazawa , Atsushi Yamamoto , Tatsuji Higashi
IPC分类号： A61M500
CPC分类号： A61M5/16877 , A61M5/141 , Y10T137/2559 , Y10T137/7839
摘要： A compact liquid discharge regulator is provided at low cost by arranging a channel spirally formed in the surf ace of a passage forming member. The surface of the passage forming member is brought into close contact with the inner surface of a housing part, and the channel functions as a liquid passage. In this construction, the sectional form and length of the channel can be formed at high precision in accordance with the design. Therefore, a desired pipe loss is obtainable only by designing in advance the sectional form and length of the channel so as to correspond to the pipe loss. Particularly, with injection molding, mass production of a passage forming member of identical pipe loss can be effected merely by preparing a mold corresponding to the pipe loss, thus leading to a considerable reduction in the manufacturing cost of the discharge regulator.
摘要翻译：通过在通道形成构件的冲浪中螺旋地形成通道来以低成本提供紧凑的液体排出调节器。通道形成构件的表面与壳体部分的内表面紧密接触，并且通道用作液体通道。在这种结构中，可以根据设计高精度地形成通道的截面形状和长度。因此，只有通过预先设计通道的截面形式和长度以便对应于管道损失，才能获得期望的管道损失。特别地，通过注射成形，可以仅通过制备与管道损失相对应的模具来实现大量生产具有相同管道损失的通道形成构件，从而导致放电调节器的制造成本的显着降低。

93. 发明授权

US06270481B1 Patient-controlled medication delivery system 失效
标题翻译：患者控制的药物输送系统
公开(公告)号：US06270481B1
公开(公告)日：2001-08-07
申请号：US09334856
申请日：1999-06-16
申请人： Bradley R. Mason , Jeffrey T. Mason
发明人： Bradley R. Mason , Jeffrey T. Mason
IPC分类号： A61M500
CPC分类号： A61M5/1424 , A61M5/14244 , A61M5/1456
摘要： A portable, patient-controlled medication delivery system includes an infusion pump, a catheter assembly and an extension tubing set. The infusion pump retains a treatment fluid and provides a drive mechanism for delivering the treatment fluid to a patient. The catheter assembly has a medicine catheter which penetrates directly into the treatment site of the patient and the extension tubing set has an extension tube which connects the medicine catheter and infusion pump. The infusion pump includes a fluid reservoir, a dosage chamber, and a displacement piston displacable within the dosage chamber. An elastic member is also positioned in the infusion pump to exert a displacement force on the displacement piston. The elastic member is alternately transitionable between a more stressed position and a less stressed position. The elastic member elastically displaces the displacement piston in a first direction to expand the dosage chamber and draw the treatment fluid from the fluid reservoir into the dosage chamber when the elastic member transitions from the more stressed position to the less stressed position. The displacement piston is manually displaced in a second direction to contract the dosage chamber and discharge the treatment fluid from the dosage chamber to the treatment site when the elastic member transitions from the less stressed position to the more stressed position.
摘要翻译：便携式，患者控制的药物输送系统包括输液泵，导管组件和延伸管组。输注泵保持处理流体并提供用于将治疗流体递送到患者的驱动机构。导管组件具有直接穿入患者治疗部位的药导管，延伸管组具有连接药导管和输液泵的延伸管。输注泵包括流体储存器，剂量室和位于剂量室内的置换活塞。弹性构件也定位在输注泵中以在位移活塞上施加位移力。弹性构件在更受应力的位置和较小的应力位置之间可交替地转换。当弹性构件从较受应力的位置转变到较小的应力位置时，弹性构件沿着第一方向弹性移位位移活塞以扩展剂量室并将处理流体从流体储存器抽出到剂量室中。当弹性构件从较小的应力位置转变到较受应力的位置时，位移活塞在第二方向上手动地移位以收缩剂量室并将处理流体从剂量室排出到治疗部位。

94. 发明授权

US06267750B1 Set with angled needle 失效
标题翻译：用角针设置
公开(公告)号：US06267750B1
公开(公告)日：2001-07-31
申请号：US09116422
申请日：1998-07-15
申请人： David S. Utterberg
发明人： David S. Utterberg
IPC分类号： A61M500
CPC分类号： A61M5/158 , A61M1/16 , A61M5/3216 , A61M2005/1581
摘要： A cannula or needle set for fluid flow connection with the vascular system of a patient. In one embodiment, the set comprises a hollow, hypodermic needle having a longitudinal axis and a sharp end for skin penetration and connection with the vascular system. A hollow hub carries the needle at a needle opposite to the sharp end. A fluid flow port is defined in the hub at a position laterally spaced from the axis of the needle. An injection site aperture is defined in the hub at a position centrally intersected by the needle axis, the injection site aperture being closed by a recloseable, needle-penetrable wall.
摘要翻译：用于与患者的血管系统流体连通的插管或针组。在一个实施例中，该组包括中空的皮下注射针，其具有纵向轴线和用于皮肤穿透并与血管系统连接的尖端。中空的轮毂将针头固定在与尖端相对的针上。流体流动端口在与针的轴线横向间隔开的位置处限定在毂中。注射部位孔在轮毂中在与针轴中心相交的位置处限定，注射部位孔被可再封闭的针穿透壁封闭。

95. 发明授权

US06267748B1 Needle-retracting needle holder and syringe 失效
标题翻译：针回针针和注射器
公开(公告)号：US06267748B1
公开(公告)日：2001-07-31
申请号：US09341436
申请日：1999-08-23
申请人： Morten Gulliksen , Helge Kristiansen
发明人： Morten Gulliksen , Helge Kristiansen
IPC分类号： A61M500
CPC分类号： A61M5/3234
摘要： The invention relates to a needle bolder, for use in combination with a syringe and a needle, characterized in that the needle holder is provided with an expandable element and with retention means for the expandable element, so that contact of the expandable element with an injection causes expansion of the expandable element and, as a consequence retraction of the needle into the needle holder. The invention relates too to a syringe comprising said needle holder.
摘要翻译：本发明涉及一种用于与注射器和针头组合使用的针头胆汁，其特征在于，针保持器设置有可膨胀元件，并具有用于可膨胀元件的保持装置，使得可膨胀元件与注射器引起可膨胀元件的膨胀，并且因此将针退回到针架中。本发明也涉及包括所述针保持器的注射器。

96. 发明授权

US06264625B1 Method and apparatus for treating adult-onset dementia of the Alzheimer's type 失效
标题翻译：治疗老年痴呆症成人发痴呆的方法和装置
公开(公告)号：US06264625B1
公开(公告)日：2001-07-24
申请号：US08901023
申请日：1997-07-25
申请人： Edward Rubenstein , David L. Karshmer , Elliot C. Levinthal , Jaime S. Vargas , Tom A. Saul
发明人： Edward Rubenstein , David L. Karshmer , Elliot C. Levinthal , Jaime S. Vargas , Tom A. Saul
IPC分类号： A61M500
CPC分类号： A61M27/006
摘要： A method for treating a patient for adult-onset dementia of the Alzheimer's type by removing a portion of the patient's cerebrospinal fluid, preferably (although not necessarily) by transporting the fluid to another portion of the patient's body. The invention also provides an apparatus for removing cerebrospinal fluid including (1) a conduit with a first opening and a second opening, the first opening of the conduit being adapted to be disposed in fluid communication with a space within a patient's subarachnoid space, the second opening being adapted to be disposed in fluid communication with another portion of the patient's body; and (2) a flow rate control device attached to the conduit.
摘要翻译：通过将流体运送到患者身体的另一部分，优选地（尽管不是必需），通过去除患者的脑脊液的一部分来治疗患者成年人阿尔茨海默氏型痴呆症的方法。本发明还提供了一种用于去除脑脊液的装置，包括（1）具有第一开口和第二开口的导管，所述导管的第一开口适于与患者的蛛网膜下腔内的空间流体连通地设置，开口适于被设置成与患者身体的另一部分流体连通; 和（2）安装在导管上的流量控制装置。

97. 发明授权

US06261268B1 Needleless injection site 有权
标题翻译：无针注射部位
公开(公告)号：US06261268B1
公开(公告)日：2001-07-17
申请号：US09226664
申请日：1999-01-08
申请人： B{overscore (r)}üno Franz P. Mayer
发明人： B{overscore (r)}üno Franz P. Mayer
IPC分类号： A61M500
CPC分类号： A61M39/045 , A61M39/26 , A61M2039/267 , Y10S604/905
摘要： A needleless injection site comprising a housing defining proximal and distal ends and including a reseal member disposed therein. The reseal member has an elastically openable and closable aperture formed therein, and normally resides within the housing in a closed position wherein the aperture is in a closed configuration. The reseal member is deformable such that the application of distally directed pressure thereto will cause the reseal member to distally advance within the housing to an open position wherein the aperture assumes an open configuration. The removal of the distally directed pressure from the reseal member will cause it to resiliently return to the closed position wherein the aperture assumes the closed configuration.
摘要翻译：一种无针注射部位，包括限定近端和远端的壳体，并且包括设置在其中的重新密封构件。重新密封构件具有形成在其中的可弹性打开和关闭的孔，并且通常位于壳体内处于闭合位置，其中孔处于闭合构型。重新密封构件是可变形的，使得向其施加远离定向的压力将导致重新密封构件在壳体内向远侧前进到打开位置，其中孔呈现打开构型。从重新密封构件去除远端定向的压力将使其弹性地返回到关闭位置，其中孔呈现闭合构型。

98. 发明授权

US06248095B1 Low-cost medication delivery pen 失效
标题翻译：低成本药物输送笔
公开(公告)号：US06248095B1
公开(公告)日：2001-06-19
申请号：US09027607
申请日：1998-02-23
申请人： Lucio Giambattista , Carlos Guillermo , John Burbank
发明人： Lucio Giambattista , Carlos Guillermo , John Burbank
IPC分类号： A61M500
CPC分类号： A61M5/31593 , A61M5/24 , A61M5/31551 , A61M5/31558 , A61M5/31561 , A61M5/31585 , A61M2205/581 , A61M2205/582
摘要： A medication delivery pen having very few parts allowing it to be manufactured at a very low-cost. The medication delivery pen also includes an automatic release mechanism to allow the user to easily reset the dose on the medication delivery pen and a mechanism for allowing the lead screw to easily retract back into the body of the medication delivery pen when the vial retainer has been removed to receive a new vial.
摘要翻译：具有很少零件的药物输送笔允许以非常低的成本制造。药物输送笔还包括自动释放机构，以允许使用者容易地重新设置药物输送笔上的剂量，以及一种机构，用于当小瓶保持器已被使用时允许导螺杆容易地缩回到药物输送笔的主体内移除以接收新的小瓶。

99. 发明授权

US06248093B1 Compact pump drive system 有权
标题翻译：紧凑型泵驱动系统
公开(公告)号：US06248093B1
公开(公告)日：2001-06-19
申请号：US09429352
申请日：1999-10-28
申请人： Sheldon Moberg
发明人： Sheldon Moberg
IPC分类号： A61M500
CPC分类号： A61M5/162 , A61M5/1452 , A61M5/1456 , A61M5/14566 , A61M5/16831 , A61M39/10 , A61M39/12 , A61M39/14 , A61M2005/1623 , A61M2205/581 , A61M2205/582 , Y10S128/12
摘要： An improved pump is provided for controlled delivery of fluids wherein the pump includes a reservoir and a movable piston. A plunger slide is in removable contact with the movable piston. A motor, is operably coupled to a drive member, such as a drive screw. The motor is disposed in-line with the drive member and the plunger slide. The drive member is operably connected to the plunger slide and is disposed to be substantially enclosed by the plunger slide when the plunger slide is in at least one position. The drive member is adapted to advance the plunger slide in response to operation of the motor.
摘要翻译：提供改进的泵用于控制输送流体，其中泵包括储存器和活动活塞。柱塞滑块与可移动活塞可拆卸接触。电动机可操作地联接到诸如驱动螺杆的驱动构件。马达与驱动部件和柱塞滑块配合配置。驱动构件可操作地连接到柱塞滑块，并且当柱塞滑块处于至少一个位置时被布置为基本上被柱塞滑块封闭。驱动构件适于响应于电动机的操作而推进柱塞滑块。

100. 发明授权

US06247485B1 Miniature valve for filling the reservoir of an apparatus for the transdermal administration of medicine 有权
标题翻译：用于填充用于透皮给药的装置的储存器的微型阀
公开(公告)号：US06247485B1
公开(公告)日：2001-06-19
申请号：US09285000
申请日：1999-07-20
申请人： Carole Rossi , Philippe Millot , Daniel Esteve , Claude Mikler , Eric Teillaud
发明人： Carole Rossi , Philippe Millot , Daniel Esteve , Claude Mikler , Eric Teillaud
IPC分类号： A61M500
CPC分类号： F16K99/0001 , A61M37/00 , A61M2205/0244 , F15C5/00 , F16K99/003 , F16K99/0067 , F16K2099/0074 , F16K2099/008 , F16K2099/0086 , Y10T137/1647
摘要： A miniature valve for filling the reservoir of an apparatus for the transdermal administration of a medicine including a) a substrate, b) a fuel charge arranged on the substrate opposite the passage to be opened through it, and c) an electric resistor placed in contact with the fuel charge so that the supply of this resistor with a predetermined electric energy ensures the combustion of the charge and the opening of the passage by local rupture of the substrate under the pressure of the fuel gases of the charge. The device is useful for filling a medicine reservoir for the transdermal administration medicine aided by inophoresis.
摘要翻译：一种用于填充用于经皮给药的药物的储存器的微型阀，包括：a）基底; b）布置在所述基底上的燃料电荷，所述燃料电荷与所述待通过的通道相对; c）电阻器，燃料电荷使得具有预定电能的该电阻器的供应通过在电荷的燃料气体的压力下的基板的局部破裂来确保电荷的燃烧和通道的打开。该装置可用于填充用于透皮给药药物的药物储存器，辅助通过吸气。

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